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Nature Medicine, ISSN 1078-8956, 01/2013, Volume 19, Issue 1, pp. 57 - 64
Chemotherapeutic agents are widely used for cancer treatment. In addition to their direct cytotoxic effects, these agents harness the host's immune system,... 
MEDICINE, RESEARCH & EXPERIMENTAL | CANCER-CHEMOTHERAPY | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GEMCITABINE | BETA | CELL BIOLOGY | 5-FLUOROURACIL | INHIBITION | MICROENVIRONMENT | ANTITUMOR IMMUNITY | BEARING MICE | T-CELLS | Neoplasms - metabolism | Cell Proliferation | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Cathepsin B - genetics | Humans | Caspase 1 - metabolism | Deoxycytidine - pharmacology | Signal Transduction - immunology | Neoplasms - genetics | RNA Interference | Female | Antineoplastic Agents - pharmacology | Interleukin-1beta - biosynthesis | Dendritic Cells - metabolism | bcl-2-Associated X Protein - genetics | Interleukin-17 - secretion | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cathepsin B - metabolism | Mice, Knockout | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Caspase 1 - genetics | Cell Line, Tumor | Fluorouracil - pharmacology | Mice | Mice, Inbred BALB C | RNA, Small Interfering | Receptors, Interleukin-1 - antagonists & inhibitors | Deoxycytidine - analogs & derivatives | Chemotherapy | Gemcitabine | Cathepsins | Physiological aspects | Dosage and administration | Research | Health aspects | Fluorouracil | Cancer | Cells | Inflammatory diseases | Tumors | Engineering Sciences | Automatic
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 7, p. e11765
Background: Chronic inflammation of the arterial wall is a key element in the pathogenesis of atherosclerosis, yet the factors that trigger and sustain the... 
FATTY STREAKS | SELECTIVE INHIBITOR | TOLL-LIKE RECEPTOR-4 | MULTIDISCIPLINARY SCIENCES | INNATE IMMUNE-RESPONSE | GENE-EXPRESSION | EPOXYSUCCINYL PEPTIDES | SMOOTH-MUSCLE CELLS | CATHEPSIN-B | NALP3 INFLAMMASOME | CUTTING EDGE | Potassium - metabolism | RNA, Small Interfering - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - metabolism | Cytoplasm - metabolism | Monocytes - metabolism | Chromatography, Thin Layer | Cytochalasin D - pharmacology | Cholesterol - chemistry | Lysosomes - metabolism | Interleukin-1beta - metabolism | Carrier Proteins - physiology | Lysosomes - drug effects | Phagocytosis - drug effects | Cells, Cultured | Phagocytosis - physiology | Cathepsin B - metabolism | RNA, Small Interfering - physiology | Inflammation - immunology | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Caspase Inhibitors | Blotting, Western | Monocytes - drug effects | Carrier Proteins - genetics | Microscopy, Confocal | Macrophages - metabolism | Lipopolysaccharides - pharmacology | Cholesterol - pharmacology | Inflammation - genetics | Macrophages - drug effects | Cathepsins | Inflammation | Interleukins | Macrophages | Cholesterol | Atherosclerosis | Atherogenesis | Pathogenesis | Interleukin | Lipids | Esters | Activation | Regulatory sequences | Caspase-1 | Proteins | Cell activation | E coli | Cathepsin B | Occupational health | Lipid metabolism | Lesions | Enzymes | Cytokines | Secretion | Crystals | Caspase | Metabolism | Gene expression | Interleukin 18 | Monocytes | Microscopy | Arteriosclerosis | Cholera | Destabilization | Cytoplasm | Apoptosis
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2011, Volume 186, Issue 11, pp. 6119 - 6128
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2009, Volume 36, Issue 1, pp. 15 - 27
The multifunctional, stress-inducible molecular chaperone HSP70 has important roles in aiding protein folding and maintaining protein homeostasis. HSP70... 
PROTEINS | CHEMBIO | CELLCYCLE | CANCER-CELLS | HSP70 | CHAPERONE-MEDIATED AUTOPHAGY | NEGATIVE REGULATION | LYSOSOMAL MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEAT-SHOCK RESPONSE | APAF-1 APOPTOSOME | P53 PROTEINS | P62 | CELL-DEATH | CELL BIOLOGY | HSP70 Heat-Shock Proteins - antagonists & inhibitors | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Humans | NF-kappa B - metabolism | Cathepsin L - metabolism | Autophagy - drug effects | DNA-Binding Proteins - metabolism | Caspases - metabolism | Lysosomes - metabolism | Protein Binding - drug effects | Lymphoma - pathology | Protein Interaction Domains and Motifs | Cell Death - drug effects | Lysosomes - drug effects | Cell Survival - drug effects | HSP40 Heat-Shock Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | HSP70 Heat-Shock Proteins - genetics | Mice, Transgenic | Mice, Inbred Strains | Sulfonamides - pharmacology | Apoptotic Protease-Activating Factor 1 - metabolism | HSP70 Heat-Shock Proteins - metabolism | Transcription Factors - metabolism | Animals | Sulfonamides - therapeutic use | Lymphoma - prevention & control | Sulfonamides - metabolism | Cell Line, Tumor | Mice | Adaptor Proteins, Signal Transducing - metabolism | Protein Multimerization - drug effects | Protein Binding - physiology | Proteins | Heat shock proteins | Analysis | Tumors
Journal Article
Cancer Research, ISSN 0008-5472, 2017, Volume 77, Issue 24, pp. 7027 - 7037
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2009, Volume 5, Issue 8, p. e1000559
The intraerythrocytic parasite Plasmodium-the causative agent of malaria-produces an inorganic crystal called hemozoin (Hz) during the heme detoxification... 
APOPTOSIS | INNATE IMMUNE RECEPTORS | INTERLEUKIN-1-BETA | MACROPHAGES | CASPASE-1 INFLAMMASOME | MICROBIOLOGY | KAPPA-B | NALP3 INFLAMMASOME | RESPONSES | VIROLOGY | IN-VIVO | MICE | PARASITOLOGY | Potassium - metabolism | Reactive Oxygen Species - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Protein-Tyrosine Kinases - metabolism | Humans | Caspase 1 - metabolism | Male | Caspase 1 - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Hemeproteins - immunology | Signal Transduction - immunology | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | src-Family Kinases - metabolism | Cytoskeletal Proteins - metabolism | Female | Interleukin-1beta - biosynthesis | Phosphorylation - immunology | Malaria - metabolism | Syk Kinase | Carrier Proteins - immunology | Disease Models, Animal | Neutrophil Infiltration - immunology | Calcium-Binding Proteins - metabolism | Carrier Proteins - physiology | Apoptosis Regulatory Proteins - immunology | Plasmodium chabaudi - chemistry | Hemeproteins - metabolism | Malaria - immunology | Mice, Inbred C57BL | Cathepsin B - metabolism | Inflammation - immunology | Plasmodium chabaudi - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Malaria - parasitology | Proteomics | HSP90 Heat-Shock Proteins - metabolism | Hemeproteins - physiology | Mice | Phagocytosis | Hostages | Inflammation | Malaria | Phosphotransferases | Medical research | Salmonella | Phosphorylation | Lipids | Parasites | Experiments | Fever | Tropical diseases
Journal Article
Neuron, ISSN 0896-6273, 2006, Volume 51, Issue 6, pp. 703 - 714
Journal Article
Cell Cycle, ISSN 1538-4101, 06/2012, Volume 11, Issue 12, pp. 2285 - 2302
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 07/2013, Volume 228, Issue 7, pp. 1506 - 1515
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2009, Volume 182, Issue 10, pp. 6460 - 6469
Journal Article