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Journal of Neurochemistry, ISSN 0022-3042, 08/2013, Volume 126, Issue 4, pp. 541 - 549
Inflammation and iron accumulation are present in a variety of neurodegenerative diseases that include Alzheimer's disease and Parkinson's disease. The study... 
neurodegeneration | hepcidin | DMT | iron accumulation | FPN | inflammation | FPN1 | DMT1 | PARKINSONIAN-PATIENTS | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DM1 | CEREBROSPINAL-FLUID | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | EPITHELIAL-CELLS | GROWTH-FACTOR-ALPHA | REGULATORY HORMONE HEPCIDIN | TNF-ALPHA | BRAIN | Antimicrobial Cationic Peptides - immunology | Microglia - metabolism | Nerve Degeneration - genetics | Male | Neurons - cytology | Antimicrobial Cationic Peptides - metabolism | RNA, Messenger - metabolism | Nerve Degeneration - metabolism | Microglia - immunology | Astrocytes - immunology | Cation Transport Proteins - metabolism | Hepcidins | Encephalitis - metabolism | Tumor Necrosis Factor-alpha - immunology | Cation Transport Proteins - genetics | Female | Neurons - metabolism | Antimicrobial Cationic Peptides - genetics | Astrocytes - cytology | Microglia - cytology | Brain - cytology | Encephalitis - genetics | Neurons - immunology | Rats | Encephalitis - immunology | Nerve Degeneration - immunology | Iron - metabolism | Rats, Sprague-Dawley | Fetus - cytology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Interleukin-6 - pharmacology | Interleukin-6 - immunology | Lipopolysaccharides - pharmacology | Primary Cell Culture | Brain - immunology | Cation Transport Proteins - immunology | Astrocytes - metabolism | Nervous system diseases | Analysis | Amyloid beta-protein | Central nervous system | Development and progression | Iron | Inflammation | Mitogens | Alzheimer's disease | Neurochemistry | Cytokines | Gene expression | Neurodegeneration | Neurological disorders | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 697 - 710
Macrophages possess numerous mechanisms to combat microbial invasion, including sequestration of essential nutrients, like zinc (Zn). The pleiotropic cytokine... 
ACTIVATION | HOMEOSTASIS | METALLOTHIONEIN | GROWTH | GENE-EXPRESSION | CALPROTECTIN | IMMUNOLOGY | PROTEINS | ZINC | HISTOPLASMA-CAPSULATUM | FAMILY | Phagosomes - microbiology | Zinc - metabolism | Golgi Apparatus - drug effects | Humans | STAT5 Transcription Factor - immunology | NADPH Oxidases - immunology | Histoplasma - drug effects | Histoplasmosis - microbiology | Superoxides - immunology | Histoplasmosis - immunology | STAT5 Transcription Factor - genetics | Phagosomes - immunology | Superoxides - metabolism | NADPH Oxidases - genetics | Zinc - immunology | Cation Transport Proteins - genetics | Golgi Apparatus - immunology | Macrophages, Peritoneal - drug effects | STAT3 Transcription Factor - genetics | Metallothionein - immunology | Phagosomes - drug effects | Signal Transduction | Gene Expression Regulation | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Macrophages, Peritoneal - immunology | Mice, Transgenic | Macrophage Activation | Histoplasma - immunology | Host-Pathogen Interactions | Histoplasmosis - metabolism | Animals | Golgi Apparatus - microbiology | Macrophages, Peritoneal - microbiology | Metallothionein - genetics | Mice | STAT3 Transcription Factor - immunology | Cation Transport Proteins - immunology | Oxidases | Zinc compounds | Superoxide | Molecular genetics | Macrophages | Environmental health | Experiments | Exports | Proteomics | Streptococcus infections | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2007, Volume 104, Issue 43, pp. 17040 - 17045
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2006, Volume 103, Issue 45, pp. 16942 - 16947
Staphylococcus aureus is the most common cause of hospitalacquired infection. Because of the emergence of antibiotic-resistant strains, these infections... 
Antigens | Immunization | Kidneys | Vaccination | Combined vaccines | Antibodies | Infections | Immunity | Staphylococcus | Membrane proteins | Disease protection | Reverse vaccinology | Opsonophagocytosis | UNITED-STATES | INFECTIONS | CONJUGATE VACCINE | MULTIDISCIPLINARY SCIENCES | reverse vaccinology | COLONIZATION | opsonophagocytosis | SORTASE | MODEL | VIRULENCE | GENOME | CELL-WALL | SURVEILLANCE | disease protection | Bacterial Vaccines - genetics | Humans | Antigens, Bacterial - immunology | Vaccines, Combined - administration & dosage | Antigens, Bacterial - genetics | Antigens, Surface - administration & dosage | Calcium-Binding Proteins - immunology | Vaccines, Combined - genetics | Cation Transport Proteins - genetics | Female | Bacterial Proteins - immunology | Staphylococcus aureus - genetics | Staphylococcal Infections - immunology | Membrane Proteins - genetics | Antigens, Surface - genetics | Bacterial Proteins - genetics | Membrane Proteins - immunology | Antigens, Bacterial - administration & dosage | Staphylococcus aureus - pathogenicity | Abscess - prevention & control | Bacterial Proteins - administration & dosage | Calcium-Binding Proteins - administration & dosage | Membrane Proteins - administration & dosage | Animals | Bacterial Vaccines - administration & dosage | Staphylococcal Infections - prevention & control | Staphylococcus aureus - immunology | Mice | Mice, Inbred BALB C | Cation Transport Proteins - administration & dosage | Cation Transport Proteins - immunology | Calcium-Binding Proteins - genetics | Prevention | Management | Drug therapy | Staphylococcus aureus | Public health | Disease prevention | Staphylococcus infections | Vaccines | Index Medicus | Biological Sciences
Journal Article
Diabetes, ISSN 0012-1797, 01/2016, Volume 65, Issue 1, pp. 285 - 296
The rapid rise in the incidence of type 1 diabetes (T1D) suggests the involvement of environmental factors including viral infections. We evaluated the... 
UNITED-STATES | BETA-CELLS | IN-VIVO | ENDOCRINOLOGY & METABOLISM | ISLET AUTOIMMUNITY | POLYMERASE CHAIN-REACTION | COXSACKIE-B | CYTOMEGALOVIRUS-INFECTION | BARR-VIRUS INFECTION | ENTEROVIRUS INFECTIONS | IGM RESPONSES | Zinc Transporter 8 | Humans | Mumps virus - immunology | Rotavirus - immunology | Viral Proteins - immunology | Child, Preschool | Male | Cytomegalovirus Infections - immunology | Case-Control Studies | Young Adult | Adult | Female | Rubella virus - immunology | Diabetes Mellitus, Type 1 - immunology | Epstein-Barr Virus Infections | Glutamate Decarboxylase - immunology | Child | Mumps - immunology | Rubella - immunology | Diabetes Mellitus, Type 1 - virology | Herpesvirus 4, Human - immunology | Rotavirus Infections - immunology | Cytomegalovirus - immunology | Autoantibodies - immunology | High-Throughput Screening Assays | Adolescent | Proteomics | Enterovirus B, Human - immunology | Protein Array Analysis | Antibodies, Viral - immunology | Endogenous Retroviruses - immunology | Cation Transport Proteins - immunology | Coxsackievirus Infections - immunology | Viral antibodies | Virus diseases | Antiviral agents | Care and treatment | Type 1 diabetes | Antibodies | Dosage and administration | Viruses | Immunoglobulins | Diabetes | Viral infections | Index Medicus | Abridged Index Medicus | Metabolomics | Genetics | Genomes
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149638 - e0149638
Vaccination strategies for Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA) infections have attracted much research attention. Recent... 
UNITED-STATES | ANTIBODIES | COMMUNITY-ASSOCIATED MRSA | EFFICACY | MULTIDISCIPLINARY SCIENCES | RESISTANCE | COLONIZATION | VIRULENCE | Immunodominant Epitopes - immunology | Epitope Mapping | Humans | Antigens, Bacterial - immunology | Epitopes, B-Lymphocyte - immunology | Vaccines, Synthetic - immunology | Vaccines, Conjugate - immunology | Antibodies, Bacterial - biosynthesis | Cation Transport Proteins - genetics | Female | Bacterial Proteins - immunology | Hemocyanins - immunology | Staphylococcal Vaccines - immunology | Staphylococcal Infections - immunology | Bacterial Proteins - genetics | Staphylococcal Vaccines - administration & dosage | Methicillin-Resistant Staphylococcus aureus - immunology | Animals | Staphylococcal Vaccines - genetics | HL-60 Cells | Antibodies, Bacterial - immunology | Staphylococcal Infections - prevention & control | Mice | Mice, Inbred BALB C | Cation Transport Proteins - immunology | Phagocytosis | Manganese | Prevention | Bacterial proteins | Staphylococcus aureus infections | Physiological aspects | Genetic aspects | Research | Antigenic determinants | Peptides | Vaccination | Lymphocytes T | Infections | Vaccines | Drug resistance | Antibody response | Methicillin | Proteins | Immunology | Gastroenterology | Epitope mapping | Synthetic peptides | Protein transport | Crystal structure | Recombinant | Killing | Antigens | Immunization | Immunoglobulins | Nutrition | Staphylococcus infections | Protein C | Immune response (humoral) | Lymphocytes B | Engineering research | Pharmacy | Transport | Index Medicus
Journal Article
Haematologica, ISSN 0390-6078, 11/2010, Volume 95, Issue 11, pp. 1814 - 1822
Background Macrophages play a key role in iron homeostasis. In peripheral tissues, they are known to polarize into classically activated (or M1) macrophages... 
Macrophages | Inflammation | Iron | HOMEOSTASIS | ERYTHROPHAGOCYTOSIS | CELL-MEDIATED-IMMUNITY | MOUSE | HUMAN MONOCYTES | SKELETAL-MUSCLE | macrophages | IN-VITRO | inflammation | GROWTH | NITRIC-OXIDE | iron | DIFFERENTIATION | HEMATOLOGY | Cation Transport Proteins - biosynthesis | Iron Regulatory Protein 2 - immunology | Iron Regulatory Protein 1 - immunology | Interferon-gamma - metabolism | Iron Regulatory Protein 2 - biosynthesis | Inflammation - metabolism | Interleukin-4 - pharmacology | Apoferritins - immunology | T-Lymphocytes - metabolism | Macrophages - immunology | Macrophage Activation - physiology | Receptors, Transferrin - biosynthesis | Interleukin-4 - metabolism | Gene Expression Regulation - physiology | Iron - immunology | Inflammation - immunology | Macrophages - cytology | Iron - metabolism | Gene Expression Regulation - drug effects | Apoferritins - biosynthesis | Interleukin-4 - immunology | Macrophages - metabolism | Animals | T-Lymphocytes - cytology | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Receptors, Transferrin - immunology | T-Lymphocytes - immunology | Mice | Macrophage Activation - drug effects | Iron Regulatory Protein 1 - biosynthesis | Lymphocyte Activation - physiology | Cation Transport Proteins - immunology | Interferon-gamma - pharmacology | Bone marrow | Index Medicus | Original
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2015, Volume 469, Issue 2, pp. 267 - 278
Mammalian colon harbours trillions of bacteria under physiological conditions; this symbiosis is made possible because of a tolerized response from the mucosal... 
Bacterial metabolites | Dendritic cell | Histone deacetylase | Colon cancer | Solute carrier gene family 5a | Butyrate transporter | Indoleamine 2,3-dioxygenase 1 | Member 8 (Slc5a8)-null mouse | Dietary fibre | Colitis | colitis | DENDRITIC CELLS | colon cancer | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDOLEAMINE 2,3-DIOXYGENASE | RECEPTOR | member 8 (Slc5a8)-null mouse | histone deacetylase | bacterial metabolites | RETINOIC ACID | INHIBITION | PIGMENT EPITHELIAL-CELLS | HISTONE DEACETYLASES | RELEVANCE | solute carrier gene family 5a | butyrate transporter | FERMENTATION | dietary fibre | BUTYRATE | indoleamine 2,3-dioxygenase 1 | dendritic cell | Fatty Acids - immunology | Forkhead Transcription Factors - immunology | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Colonic Neoplasms - genetics | Colitis - genetics | Dendritic Cells - immunology | Immunity, Mucosal | Dendritic Cells - pathology | Colitis - pathology | Colon - immunology | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Colonic Neoplasms - immunology | Fatty Acids - genetics | Tumor Suppressor Proteins - genetics | Histamine Antagonists - pharmacology | Cation Transport Proteins - genetics | Butyric Acid - pharmacology | Interferon-gamma - genetics | Colitis - immunology | Immune Tolerance - drug effects | Dietary Fiber - pharmacology | Colon - pathology | Aldehyde Dehydrogenase - genetics | Forkhead Transcription Factors - genetics | Tumor Suppressor Proteins - immunology | Mice, Knockout | Animals | Colonic Neoplasms - pathology | Interferon-gamma - immunology | Immune Tolerance - genetics | Mice | Aldehyde Dehydrogenase - immunology | Cation Transport Proteins - immunology | Index Medicus | dietary fiber | Slc5a8-null mouse
Journal Article
Nature Immunology, ISSN 1529-2908, 03/2019, Volume 20, Issue 3, pp. 350 - 361
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 08/2012, Volume 92, Issue 2, pp. 353 - 359
Journal Article