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1. Full Text Transmission of prion diseases by blood transfusion
by Hunter, Nora and Foster, James and Chong, Angela and McCutcheon, Sandra and Parnham, David and Eaton, Samantha and MacKenzie, Calum and Houston, Fiona
Journal of General Virology, ISSN 0022-1317, 11/2002, Volume 83, Issue 11, pp. 2897 - 2905
Institute for Animal Health, Neuropathogenesis Unit, West Mains Road, Edinburgh EH9 3JF, UK 1 Institute for Animal Health, Compton, Newbury, Berkshire RG20... 
VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN EXPRESSION | SPONGIFORM ENCEPHALOPATHY BSE | NATURAL SCRAPIE | SHEEP | INFECTIVITY | CREUTZFELDT-JAKOB-DISEASE | VARIANT | BRAIN | MOLECULAR ANALYSIS | PRP | Immunohistochemistry - methods | Prion Diseases - blood | Animals | Prion Diseases - transmission | Cattle | PrPSc Proteins - analysis | Prion Diseases - etiology | Sheep | Disease Models, Animal | Transfusion Reaction
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2. Full Text Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine
by Eckersall, P.D and Bell, R
The Veterinary Journal, ISSN 1090-0233, 2010, Volume 185, Issue 1, pp. 23 - 27
Acute phase proteins (APPs) have been used as biomarkers of inflammation, infection and trauma for decades in human medicine but have been relatively... 
Serum amyloid A | Biomarkers | C-reactive protein | Diagnosis | Haptoglobin | Acute phase proteins | BULK TANK MILK | SERUM-AMYLOID-A | RESPONSIVE MENINGITIS-ARTERITIS | SOMATIC-CELL COUNT | DAIRY-COWS | ALPHA-1-ACID GLYCOPROTEIN | VETERINARY SCIENCES | MULTICENTRIC LYMPHOMA | INTRAMAMMARY INFECTIONS | HAPTOGLOBIN CONCENTRATIONS | Cats | Species Specificity | Biomarkers - analysis | Cat Diseases - diagnosis | Infection - blood | Animal Diseases - diagnosis | Animal Diseases - blood | Cat Diseases - blood | Inflammation - blood | Animals, Domestic | Dog Diseases - blood | Inflammation - veterinary | Animals | Infection - veterinary | Cattle | Dogs | Acute-Phase Reaction - blood | Acute-Phase Proteins - analysis | Acute-Phase Reaction - veterinary | Cattle Diseases - blood | Cattle Diseases - diagnosis | Dog Diseases - diagnosis | Proteins | Veterinary supplies industry | Dairy cattle | Inflammation | Livestock | Biological markers
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3. Full Text Evaluation of nonesterified fatty acids and β-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases
by Ospina, P.A and Nydam, D.V and Stokol, T and Overton, T.R
Journal of Dairy Science, ISSN 0022-0302, 02/2010, Volume 93, Issue 2, pp. 546 - 554
The objectives of this study were to 1) establish cow-level critical thresholds for serum concentrations of nonesterified fatty acids (NEFA) and... 
nonesterified fatty acids | β-hydroxybutyrate | dairy cow | disease | Dairy cow | Disease | Nonesterified fatty acids | NEUTROPHIL FUNCTION | AGRICULTURE, DAIRY & ANIMAL SCIENCE | ASSOCIATIONS | FOOD SCIENCE & TECHNOLOGY | DRY | PREVALENCE | HOLSTEIN COWS | REPRODUCTIVE-PERFORMANCE | DISPLACED ABOMASUM | EARLY LACTATION | beta-hydroxybutyrate | HEALTH | BLOOD | Pregnancy | Predictive Value of Tests | Animals | 3-Hydroxybutyric Acid - blood | Cattle | Risk Factors | New England | Fatty Acids, Nonesterified - blood | Female | Cattle Diseases - blood | Cattle Diseases - diagnosis | Dairying - methods
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4. Full Text Prion diseases are efficiently transmitted by blood transfusion in sheep
by Houston, Fiona and McCutcheon, Sandra and Goldmann, Wilfred and Chong, Angela and Foster, James and Sisó, Silvia and González, Lorenzo and Jeffrey, Martin and Hunter, Nora
Blood, ISSN 0006-4971, 12/2008, Volume 112, Issue 12, pp. 4739 - 4745
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential... 
TISSUE SAMPLES | AGENT | EXPERIMENTAL CHALLENGE | NATURAL SCRAPIE | SUFFOLK SHEEP | INCUBATION-TIME | CREUTZFELDT-JAKOB-DISEASE | PRP ACCUMULATION | HEMATOLOGY | TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES | VARIANT | Prion Diseases - blood | Genetic Predisposition to Disease | Encephalopathy, Bovine Spongiform - transmission | Scrapie - genetics | Prion Diseases - pathology | Disease Progression | Encephalopathy, Bovine Spongiform - blood | Prion Diseases - veterinary | Transfusion Reaction | Blood Donors | Blood Transfusion - veterinary | Algorithms | Animals | Encephalopathy, Bovine Spongiform - genetics | Prion Diseases - transmission | Time Factors | Cattle | Efficiency | Scrapie - pathology | Sheep | Scrapie - transmission | Scrapie - blood | Encephalopathy, Bovine Spongiform - pathology
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5. Full Text All clinically-relevant blood components transmit prion disease following a single blood transfusion: A sheep model of vCJD
by McCutcheon, Sandra and Blanco, Anthony Richard Alejo and Houston, E. Fiona and de Wolf, Christopher and Tan, Boon Chin and Smith, Antony and Groschup, Martin H and Hunter, Nora and Hornsey, Valerie S and MacGregor, Ian R and Prowse, Christopher V and Turner, Marc and Manson, Jean C
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23169
Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic... 
PATHOGENESIS | AGENT | SCRAPIE | PROTEIN | BSE | BOVINE SPONGIFORM ENCEPHALOPATHY | MULTIDISCIPLINARY SCIENCES | CREUTZFELDT-JAKOB-DISEASE | VARIANT CJD | CHRONIC WASTING DISEASE | INFECTIOUS PRIONS | Immunohistochemistry | Prion Diseases - blood | Erythrocyte Transfusion - adverse effects | Creutzfeldt-Jakob Syndrome - transmission | Humans | PrPSc Proteins - analysis | Blood Component Transfusion - adverse effects | Immunoblotting | Creutzfeldt-Jakob Syndrome - blood | Encephalopathy, Bovine Spongiform - blood | Brain - metabolism | Platelet Transfusion - adverse effects | Blood Donors | Prion Diseases - transmission | Leukocyte Reduction Procedures | Cattle | Erythrocyte Transfusion - veterinary | Disease Models, Animal | Blood Component Transfusion - veterinary | Encephalopathy, Bovine Spongiform - transmission | Creutzfeldt-Jakob Syndrome - etiology | Animals | Prion Diseases - etiology | Brain - pathology | Platelet Transfusion - veterinary | Sheep | Biological products | Disease transmission | Blood transfusion | Creutzfeldt-Jakob disease | Blood transfusions | Epidemics | Spinal cord | Transfusion | Laboratories | Pathogenesis | Infections | Veterinary medicine | Blood | Meat | Proteins | Genotype & phenotype | Blood-brain barrier | Infectivity | Meat products | Spleen | Vectors | Disease control | Platelets
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6. Full Text Population Screening for Variant Creutzfeldt-Jakob Disease Using a Novel Blood Test: Diagnostic Accuracy and Feasibility Study
by Jackson, Graham S and Burk-Rafel, Jesse and Edgeworth, Julie Ann and Sicilia, Anita and Abdilahi, Sabah and Korteweg, Justine and Mackey, Jonathan and Thomas, Claire and Wang, Guosu and Schott, Jonathan M and Mummery, Catherine and Chinnery, Patrick F and Mead, Simon and Collinge, John
JAMA Neurology, ISSN 2168-6149, 04/2014, Volume 71, Issue 4, pp. 421 - 428
IMPORTANCE Our study indicates a prototype blood-based variant Creutzfeldt-Jakob disease (vCJD) assay has sufficient sensitivity and specificity to justify a... 
ASSAY | REPLICATION | TRANSFUSION | BSE | LIKELIHOOD RATIOS | TISSUE | TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY | ABNORMAL PRION PROTEIN | CONFIDENCE | CLINICAL NEUROLOGY | VCJD | Creutzfeldt-Jakob Syndrome - epidemiology | Prion Diseases - blood | United States - epidemiology | Hematologic Tests - methods | Cross-Sectional Studies | Humans | Hematologic Tests - trends | Creutzfeldt-Jakob Syndrome - blood | Feasibility Studies | Creutzfeldt-Jakob Syndrome - diagnosis | Animals | Cattle | Retrospective Studies | Prion Diseases - diagnosis | Prion Diseases - epidemiology | United Kingdom - epidemiology | Population Surveillance - methods | Cohort Studies
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7. Full Text The association of serum metabolites with clinical disease during the transition period
by Chapinal, N and Carson, M and Duffield, T.F and Capel, M and Godden, S and Overton, M and Santos, J.E.P and LeBlanc, S.J
Journal of Dairy Science, ISSN 0022-0302, 10/2011, Volume 94, Issue 10, pp. 4897 - 4903
The objective of this observational field study was to validate the relationship of serum concentrations of nonesterified fatty acids (NEFA), β-hydroxybutyrate... 
nonesterified fatty acid | β-hydroxybutyrate | displaced abomasum | hypocalcemia | Displaced abomasum | Nonesterified fatty acid | Hypocalcemia | VITAMIN-E | AGRICULTURE, DAIRY & ANIMAL SCIENCE | PERFORMANCE | FOOD SCIENCE & TECHNOLOGY | RISK | ENERGY-BALANCE | SUBCLINICAL KETOSIS | COWS | beta-hydroxybutyrate | HEALTH | DAIRY-CATTLE | Abomasum - pathology | Predictive Value of Tests | 3-Hydroxybutyric Acid - blood | United States | Stomach Diseases - blood | Logistic Models | Pregnancy | Calcium - blood | Canada | Animals | Cattle | Dairying | Fatty Acids, Nonesterified - blood | Female | Stomach Diseases - veterinary | Cattle Diseases - blood | Lactation - physiology
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8. Full Text Herd-level association of serum metabolites in the transition period with disease, milk production, and early lactation reproductive performance
by Chapinal, N and LeBlanc, S.J and Carson, M.E and Leslie, K.E and Godden, S and Capel, M and Santos, J.E.P and Overton, M.W and Duffield, T.F
Journal of Dairy Science, ISSN 0022-0302, 10/2012, Volume 95, Issue 10, pp. 5676 - 5682
The objective was to identify herd-level indicators expressed as a proportion of sampled animals with increased nonesterified fatty acids (NEFA) or... 
nonesterified fatty acid | negative energy balance | β-hydroxybutyric acid | hypocalcemia | Nonesterified fatty acid | Negative energy balance | Hypocalcemia | BETA-HYDROXYBUTYRATE | ENERGY | AGRICULTURE, DAIRY & ANIMAL SCIENCE | NONESTERIFIED FATTY-ACIDS | CULLING RISK | FOOD SCIENCE & TECHNOLOGY | CATTLE | DAIRY-COWS | beta-hydroxybutyric acid | CALCIUM | SUBCLINICAL HYPOCALCEMIA | NORTHEASTERN UNITED-STATES | KETOSIS | Cattle - blood | Stomach Diseases - blood | Endometritis - blood | Abomasum | Calcium - blood | Calcium - physiology | Stomach Diseases - physiopathology | Lactation - blood | Endometritis - physiopathology | Fatty Acids, Nonesterified - blood | Female | Stomach Diseases - veterinary | Cattle Diseases - blood | Fatty Acids, Nonesterified - physiology | 3-Hydroxybutyric Acid - blood | Pregnancy, Animal - physiology | Placenta, Retained - blood | Endometritis - veterinary | Placenta, Retained - veterinary | Pregnancy | Animals | Cattle Diseases - physiopathology | Pregnancy, Animal - blood | Placenta, Retained - physiopathology | 3-Hydroxybutyric Acid - physiology | Lactation - physiology | Cattle - physiology
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9. Full Text Metabolic profiles of cow's blood; a review
by Puppel, Kamila and Kuczyńska, Beata
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 10/2016, Volume 96, Issue 13, pp. 4321 - 4328
The term ‘metabolic profile’ refers to the analysis of blood biochemical parameters that are useful to assess and prevent metabolic and nutritional disorders... 
nonesterified fatty acid | liver | metabolic profiles | cows | lactation | β‐hydroxybutyric acid | Cows | Metabolic profiles | Nonesterified fatty acid | β-hydroxybutyric acid | Lactation | Liver | EARLY-LACTATION | DRY PERIOD | NONESTERIFIED FATTY-ACIDS | PROPYLENE-GLYCOL | FOOD SCIENCE & TECHNOLOGY | HOLSTEIN DAIRY-COWS | REPRODUCTIVE-PERFORMANCE | SUBCLINICAL KETOSIS | beta-hydroxybutyric acid | MULTIPAROUS COWS | AGRICULTURE, MULTIDISCIPLINARY | BODY CONDITION SCORE | CHEMISTRY, APPLIED | INFLAMMATORY CONDITIONS | Prenatal Nutritional Physiological Phenomena | Cattle Diseases - metabolism | Metabolic Diseases - veterinary | Cattle | Metabolomics - economics | Lactation - blood | Female | Cattle Diseases - blood | Cattle Diseases - prevention & control | Dairying - economics | Metabolome | Biomarkers - blood | Metabolic Diseases - diagnosis | Energy Intake | Metabolomics - methods | Dairying - trends | Pregnancy | Animals | Animal Nutritional Physiological Phenomena | Energy Metabolism | Metabolic Diseases - metabolism | Metabolomics - trends | Metabolic Diseases - prevention & control | Cattle Diseases - diagnosis | Lactation - physiology | Fatty acids | Analysis | Milk production | Priorities | Health | Disorders | Rations | Blood | Standards | Milk | Diseases
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10. Full Text Association between uterine disease and indicators of neutrophil and systemic energy status in lactating Holstein cows
by Galvão, K.N and Flaminio, M.J.B.F and Brittin, S.B and Sper, R and Fraga, M and Caixeta, L and Ricci, A and Guard, C.L and Butler, W.R and Gilbert, R.O
Journal of Dairy Science, ISSN 0022-0302, 07/2010, Volume 93, Issue 7, pp. 2926 - 2937
The objective of this study was to evaluate the association between uterine disease and indicators of neutrophil (PMN) and systemic energy status in dairy... 
energy balance | dairy cow | glycogen | metritis | Dairy cow | Energy balance | Metritis | Glycogen | MILK-PRODUCTION | PHAGOCYTOSIS | AGRICULTURE, DAIRY & ANIMAL SCIENCE | FOOD SCIENCE & TECHNOLOGY | CATTLE | DISORDERS | ENDOMETRITIS | HAPTOGLOBIN | METABOLISM | PERIPARTURIENT DAIRY-COWS | HEALTH | Estradiol - blood | Uterine Diseases - veterinary | Haptoglobins - analysis | Blood Glucose - analysis | 3-Hydroxybutyric Acid - blood | Uterine Diseases - blood | Uterine Diseases - physiopathology | Animals | Energy Metabolism | Time Factors | Cattle | Cattle Diseases - physiopathology | Glycogen - blood | Dairying | Fatty Acids, Nonesterified - blood | Female | Cattle Diseases - blood | Neutrophils - metabolism
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11. Full Text Metabolic predictors of post-partum disease and culling risk in dairy cattle
by Seifi, Hesam A and LeBlanc, Stephen J and Leslie, Ken E and Duffield, Todd F
The Veterinary Journal, ISSN 1090-0233, 2011, Volume 188, Issue 2, pp. 216 - 220
A retrospective study was conducted to determine the relationship between serum non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHBA), glucose and... 
Cut-point | Dairy cow | Displaced abomasum | Non-esterified fatty acids | Ketosis | Culling | DISORDERS | HYPOCALCEMIA | HERDS | COWS | EARLY LACTATION | VETERINARY SCIENCES | HEALTH | SELECTION | Blood Glucose - analysis | 3-Hydroxybutyric Acid - blood | Ketosis - diagnosis | Stomach Diseases - blood | Postpartum Period | Biomarkers - blood | Ketosis - veterinary | Euthanasia, Animal | Pregnancy | Calcium - blood | Animals | Cattle | Dairying | Ketosis - blood | Abomasum - abnormalities | Fatty Acids, Nonesterified - blood | Female | Retrospective Studies | Stomach Diseases - veterinary | Cattle Diseases - blood | Cattle Diseases - diagnosis | Stomach Diseases - diagnosis | Oncology, Experimental | Dairy cattle | Research | Glucose | Fatty acids | Dextrose | Cancer
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