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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 107, Issue 44, pp. 18880 - 18885
Journal Article
Journal of cellular and molecular medicine, ISSN 1582-1838, 2018, Volume 22, Issue 11, pp. 5573 - 5582
.... This study examined the role of caveolin‐1 (Cav‐1) in lipopolysaccharide (LPS) and D‐galactosamine (GalN)‐induced fulminant hepatic injury in wild type and Cav... 
toll‐like receptor 4 | lipopolysaccharide | caveolin‐1 | D‐galactosamine | acute liver injury | caveolin-1 | D-galactosamine | toll-like receptor 4 | MEDICINE, RESEARCH & EXPERIMENTAL | INDUCED HEPATIC-INJURY | ACTIVATION | NITRIC-OXIDE SYNTHASE | IMMUNE DYSFUNCTION | KAPPA-B | FAILURE | CELL BIOLOGY | SHOCK | DISEASE | GALACTOSAMINE-SENSITIZED MICE | Inflammation - chemically induced | Inflammation - pathology | Liver - pathology | Humans | Apoptosis - genetics | Hepatocytes - metabolism | Transcription Factor RelA - genetics | Liver - injuries | Liver - drug effects | Kupffer Cells - metabolism | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Lipopolysaccharides - toxicity | Liver - metabolism | Caveolin 1 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Chemical and Drug Induced Liver Injury - genetics | Neutrophil Infiltration - genetics | Kupffer Cells - drug effects | Animals | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Intercellular Adhesion Molecule-1 - genetics | Inflammation - genetics | Lipopolysaccharide Receptors - genetics | Mice | Liver diseases | Mitogens | Nitric oxide | Liver | Vascular cell adhesion molecule 1 | Kupffer cells | Inflammatory response | Activation | Lethality | CD14 antigen | Cell adhesion molecules | Cell adhesion & migration | Lipopolysaccharides | Signal transduction | Clonal deletion | Rodents | Cell adhesion | Toll-like receptors | Injuries | Intercellular adhesion molecule 1 | Caveolin | Caspase | TLR4 protein | Adhesion | Nitric-oxide synthase | Hepatocytes | Infiltration | Apoptosis | Original
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 4, p. e95100
Journal Article
PLoS genetics, ISSN 1553-7404, 2017, Volume 13, Issue 9, p. e1007040
Cardiovascular diseases (CVD) and type 2 diabetes (T2D) are closely interrelated complex diseases likely sharing overlapping pathogenesis driven by aberrant... 
METABOLIC SYNDROME | MULTIDIMENSIONAL DATA INTEGRATION | INSULIN-RESISTANCE | GENETICS & HEREDITY | ATHEROSCLEROSIS | MITOCHONDRIAL DYSFUNCTION | CHAIN AMINO-ACIDS | EXTRACELLULAR-MATRIX | ASSOCIATION | CORONARY-ARTERY-DISEASE | KEY REGULATORS | United States | Amino Acids, Branched-Chain - metabolism | Diabetes Mellitus, Type 2 - genetics | Humans | Glycoproteins - metabolism | Male | Insulin-Like Growth Factor I - genetics | Gene Regulatory Networks | Cardiovascular Diseases - genetics | Ethnic Groups - genetics | Hydroxymethylglutaryl CoA Reductases - metabolism | Extracellular Matrix Proteins - metabolism | Disease Models, Animal | Glycoproteins - genetics | Genome-Wide Association Study | Reproducibility of Results | Extracellular Matrix Proteins - genetics | Gene Expression Regulation | Caveolin 1 - genetics | Lipid Metabolism | Caveolin 1 - metabolism | Animals | Adipocytes - metabolism | Glucose - metabolism | Mice | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Hydroxymethylglutaryl CoA Reductases - genetics | Insulin-Like Growth Factor I - metabolism | Type 2 diabetes | Genetic aspects | Cardiovascular diseases | Gene expression | Statistics | Health aspects | Prevalence studies (Epidemiology) | Heart | Networks | Animal models | Insulin-like growth factor I | Pathogenesis | Genomics | Chain branching | Amino acids | Cardiovascular disease | Lipids | Genomes | Biology | Epidemiology | Consortia | Glucose metabolism | Metabolites | Genetics | Extracellular matrix | Physiology | Oxidation | Lipid metabolism | Immune system | Departments | Immune response | Diabetes mellitus | Calcium channels (voltage-gated) | siRNA | Metabolism | Quantitative trait loci | Medicine | Ethnicity | Collaboration | Insulin resistance | Diabetes | Aberration | Endocrinology | Life Sciences | Human health and pathology | Endocrinology and metabolism | Biochemistry, Molecular Biology | Cardiology and cardiovascular system
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 06/2015, Volume 36, Issue 3, pp. 1223 - 1236
Background/Aims: Anoikis resistance is a prerequisite for hepatocellular carcinoma (HCC) metastasis. The role of Caveolin-1 (CAV1) in anoikis resistance of HCC... 
Original Paper | Caveolin-1 | IGF-1 pathway | Hepatocellular carcinoma | Anoikis resistence | I-MEDIATED SURVIVAL | MIGRATION | APOPTOSIS | PHYSIOLOGY | METASTASIS | PHOSPHORYLATION | IDENTIFICATION | OVEREXPRESSION | INTERNALIZATION | GROWTH | EXPRESSION | RNA, Small Interfering - genetics | Receptor, IGF Type 1 - metabolism | Carcinoma, Hepatocellular - mortality | Humans | Gene Expression Regulation, Neoplastic | Insulin-Like Growth Factor I - genetics | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Liver Neoplasms - mortality | raf Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Caveolae - pathology | Carcinoma, Hepatocellular - genetics | Caveolin 1 - agonists | Liver Neoplasms - pathology | Proto-Oncogene Proteins c-akt - metabolism | raf Kinases - genetics | Caveolin 1 - antagonists & inhibitors | Liver Neoplasms - genetics | Signal Transduction | Anoikis - genetics | Caveolae - metabolism | MAP Kinase Kinase Kinases - genetics | Caveolin 1 - genetics | MAP Kinase Kinase Kinases - metabolism | Cell Adhesion | Receptor, IGF Type 1 - genetics | Caveolin 1 - metabolism | Phosphatidylinositol 3-Kinases - genetics | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Survival Analysis | Cell Line, Tumor | Mutation | Insulin-Like Growth Factor I - metabolism | Carcinoma, Hepatocellular - metabolism | RNA, Small Interfering - metabolism
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2019, Volume 116, Issue 9, pp. 3518 - 3523
Journal Article
Journal Article
Journal Article
by Chen, R-S and Song, Y-M and Zhou, Z-Y and Tong, T and Li, Y and Fu, M and Guo, X-L and Dong, L-J and He, X and Qiao, H-X and Zhan, Q-M and Li, W
Oncogene, ISSN 1476-5594, 2008, Volume 28, Issue 4, pp. 599 - 609
xCT, the functional subunit of the cystine/glutamate transporter xc- system, plays a critical role in the maintenance of intracellular glutathione and redox... 
Caveolin-1 | β-catenin | Oxidative stress | xCT/SLC7A11 | Metastasis | Cancer | beta-catenin | CYSTINE UPTAKE | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | TYROSINE KINASES | E-CADHERIN | PLASMA-MEMBRANE | CELL BIOLOGY | caveolin-1 | PREMATURE SENESCENCE | ONCOLOGY | metastasis | GENETICS & HEREDITY | cancer | oxidative stress | Neoplasms - metabolism | Transcription, Genetic - drug effects | Reactive Oxygen Species - metabolism | Humans | Amino Acid Transport System y+ - genetics | Male | Melanocytes - metabolism | Sulfasalazine - pharmacology | Cell Membrane - genetics | Neoplasm Proteins - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Neoplasm Metastasis | Amino Acid Transport System y+ - metabolism | Neoplasms - genetics | Melanocytes - pathology | Cell Membrane - pathology | Female | Cell Membrane - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Neoplasm Invasiveness | Caveolin 1 - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Up-Regulation - genetics | Enzyme Activation - drug effects | beta Catenin - metabolism | beta Catenin - genetics | Mice, Knockout | Caveolin 1 - metabolism | Up-Regulation - drug effects | Animals | Cell Line, Tumor | Mice | Transcription, Genetic - genetics | Enzyme Activation - genetics | Neoplasms - pathology
Journal Article
Nature genetics, ISSN 1546-1718, 2010, Volume 42, Issue 10, pp. 906 - 909
Journal Article