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Plos one, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e107392 - e107392
Studies with dietary supplementation of various types of fibers have shown beneficial effects on symptoms of the metabolic syndrome. Short-chain fatty acids... 
IMPROVES INSULIN SENSITIVITY | GERM-FREE-MICE | MULTIDISCIPLINARY SCIENCES | PERFECT ADAPTATION | RATS | SMALL-INTESTINE | MICROBIOTA | BUTYRATE | PROPIONIC-ACID | ENERGY-METABOLISM | INDUCED OBESITY | Biomarkers - metabolism | Plant Gums - metabolism | Galactans - metabolism | Liver - metabolism | Mice, Inbred C57BL | Dietary Fiber - metabolism | Male | Metabolic Syndrome - metabolism | Insulin - blood | Fatty Acids, Volatile - metabolism | Metabolic Syndrome - blood | Animals | Cecum - metabolism | Mannans - metabolism | Triglycerides - blood | Mice | Blood Glucose - metabolism | Body Weight - physiology | Diet, High-Fat - methods | Dietary Supplements | Synthesis | RNA | Body weight | Dietary supplements | Physiological aspects | Triglycerides | Glucose | Fatty acids | Guar | Dextrose | Pediatrics | Laboratories | Liver | Chains | Biology | Metabolic syndrome | High fat diet | Fibers | Consortia | Infusion | Ethics | Microbiota | Hyperglycemia | Energy | Intestine | Rodents | Guar gum | Aging | Bioindicators | Isotopic enrichment | Feces | Supplementation | Gluconeogenesis | Adaptation | Hypertension | Obesity | Nutrition | Propionic acid | Cecum | Fluxes | Gene expression | Fermentation | Metabolism | Insulin | Diet | Biomarkers | Insulin resistance | In vivo methods and tests | Diabetes | Dietary fiber | Acetic acid | Steady state models | Metabolic disorders | Index Medicus
Journal Article
Diabetes, ISSN 0012-1797, 2011, Volume 60, Issue 11, pp. 2775 - 2786
OBJECTIVE To investigate deep and comprehensive analysis of gut microbial communities and biological parameters after prebiotic administration in obese and... 
GLUCAGON-LIKE PEPTIDE-1 | PERMEABILITY | MECHANISM | INULIN-TYPE FRUCTANS | PHYLOGENETIC MICROARRAY | INSULIN-RESISTANCE | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | ENDOTOXEMIA | RATS | ADIPOGENESIS | Obesity - diet therapy | Leptin - metabolism | Diabetes Mellitus, Type 2 - diet therapy | Glucagon-Like Peptide 1 - blood | Cecum - microbiology | Diabetes Mellitus, Type 2 - metabolism | RNA, Messenger - metabolism | Gram-Negative Bacteria - isolation & purification | Obesity - blood | Molecular Typing | Glucose Intolerance - prevention & control | Enteroendocrine Cells - metabolism | Proglucagon - metabolism | Enteroendocrine Cells - pathology | Hyperglycemia - prevention & control | Dietary Fats - adverse effects | Colon - pathology | Mice, Inbred C57BL | Gene Expression Regulation | Hyperlipidemias - prevention & control | Colon - metabolism | Obesity - metabolism | Obesity - pathology | Prebiotics | Diabetes Mellitus, Type 2 - blood | Animals | Gram-Positive Bacteria - classification | Gram-Positive Bacteria - isolation & purification | Mice, Obese | Mice | Proglucagon - genetics | Diabetes Mellitus, Type 2 - pathology | Gram-Negative Bacteria - classification | Glucose metabolism | Obesity | Microbiota (Symbiotic organisms) | Physiological aspects | Development and progression | Research | Gene expression | Oxidative stress | Animal models | rRNA 16S | Diabetes mellitus | Homeostasis | Abundance | Feeding | Diets | Glucose tolerance | Polymerase chain reaction | DNA microarrays | Leptin | Lipid metabolism | Catalogs | Digestive tract | Glucagon-like peptide 1 | Index Medicus | Abridged Index Medicus | Metabolism | insulin-resistance | adipogenesis | inflammation | glucagon-like peptide-1 | permeability | endotoxemia | inulin-type fructans | rats | phylogenetic microarray | mechanism
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 2014, Volume 138, Issue 8, pp. 1015 - 1026
Context.-Distinction of medullary carcinoma of the large intestine from other cytokeratin (CK) 7(-)/CK20(-) carcinomas can be challenging when working on a... 
MEDICINE, RESEARCH & EXPERIMENTAL | MARKER | MICROSATELLITE INSTABILITY | COLON | PATHOLOGY | CYTOKERATIN-20 | GASTROINTESTINAL ADENOCARCINOMAS | COLORECTAL CARCINOMAS | IMMUNOHISTOCHEMICAL SURVEY | GENE-EXPRESSION | FACTOR CDX2 | DIFFERENTIATION | MEDICAL LABORATORY TECHNOLOGY | Immunohistochemistry | MutL Protein Homolog 1 | Cadherins - metabolism | Tissue Array Analysis | Cecal Neoplasms - pathology | Humans | Middle Aged | Carcinoma, Medullary - diagnosis | Colonic Neoplasms - diagnosis | Carcinoma, Medullary - metabolism | Male | Neoplasm Proteins - metabolism | Colonic Neoplasms - metabolism | Cecal Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Cecum - metabolism | Sensitivity and Specificity | DNA Repair Enzymes - metabolism | Aged, 80 and over | Female | Mismatch Repair Endonuclease PMS2 | Biomarkers - metabolism | Colon - pathology | Matrix Attachment Region Binding Proteins - metabolism | Down-Regulation | Adenosine Triphosphatases - metabolism | Cecal Neoplasms - diagnosis | Carcinoma, Medullary - pathology | Nuclear Proteins - metabolism | Tumor Burden | Colon - metabolism | Cecum - pathology | Transcription Factors - metabolism | Colonic Neoplasms - pathology | Aged | Adaptor Proteins, Signal Transducing - metabolism | Keratin | Carcinoma | Diagnosis | Colorectal cancer | Mucins | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, pp. e0142176 - e0142176
The effects of indigestible carbohydrates, protein type, and protein level on large intestine health were examined in rats. For 21 days, 12 groups of six... 
BETA-GLUCURONIDASE ACTIVITY | YOUNG-PIGS | RED MEAT | RESISTANT STARCH | POTATO FIBER | DIETARY FIBER | BACTERIAL METABOLITES | MULTIDISCIPLINARY SCIENCES | CECAL FERMENTATION | ADULT DOGS | COLONIC DNA-DAMAGE | Propionates - metabolism | Body Weight | Pectins - metabolism | Rats, Wistar | Glucuronidase - metabolism | Starch - metabolism | Nutritional Physiological Phenomena | Dietary Carbohydrates - metabolism | Fatty Acids, Volatile - metabolism | Dietary Proteins - metabolism | Intestine, Large - metabolism | Phenol - metabolism | Dietary Proteins - pharmacology | Acetic Acid - metabolism | Biomarkers - metabolism | Starch - pharmacology | Ammonia - metabolism | Colon - pathology | Dietary Carbohydrates - pharmacology | Cecum - drug effects | Colon - metabolism | Cresols - metabolism | Cecum - pathology | Pectins - pharmacology | Animals | DNA Damage | Cellulose - pharmacology | Cellulose - metabolism | Hydrogen-Ion Concentration | Ammonia | Genetic aspects | Research | Casein | Potatoes | DNA damage | Cellulose | pH effects | Metabolites | Rodents | Bioindicators | Colon | Damage | Deoxyribonucleic acid--DNA | Carbohydrates | Nutrition | Starch | Propionic acid | Cecum | Rats | Pectin | Fermentation | Fatty acids | Diet | Large intestine | Weight reduction | Phenols | Biomarkers | Dietary fiber | Acetic acid | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 534, Issue 7609, pp. 697 - 699
Changes in the gut microbiota may underpin many human diseases, but the mechanisms that are responsible for altering microbial communities remain poorly... 
ENTERICA SEROTYPE TYPHIMURIUM | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | GROWTH | SALMONELLA-TYPHIMURIUM | NITRIC-OXIDE | RESISTANCE | MICROBIOTA | INFECTION | Carbohydrate Metabolism - drug effects | Galactose - metabolism | Intestinal Mucosa - metabolism | Salmonella typhimurium - growth & development | Carbohydrate Metabolism - genetics | Gastroenteritis - microbiology | Sugar Acids - metabolism | Male | Host-Pathogen Interactions - drug effects | Cecum - microbiology | Cecum - enzymology | Intestinal Mucosa - drug effects | Salmonella typhimurium - metabolism | Intestinal Mucosa - enzymology | Oxidation-Reduction - drug effects | Glucaric Acid - metabolism | Female | Salmonella typhimurium - drug effects | Salmonella typhimurium - pathogenicity | Streptomycin - pharmacology | Reactive Nitrogen Species - metabolism | Intestinal Mucosa - microbiology | Operon - genetics | Cecum - drug effects | Animals | Nitric Oxide Synthase Type II - genetics | Glucose - metabolism | Anti-Bacterial Agents - pharmacology | Mice | Nitric Oxide Synthase Type II - metabolism | Host-bacteria relationships | Complications and side effects | Drug resistance in microorganisms | Glucose metabolism | Streptomycin | Microbiota (Symbiotic organisms) | Antibiotics | Growth | Physiological aspects | Research | Salmonella typhimurium | Inflammatory bowel disease | Carbohydrates | Pathology | Bacteria | Oxidation | Glucose | Index Medicus
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 05/2015, Volume 113, Issue 10, pp. 1558 - 1570
Mixed-linkage -glucans are fermented by the colon microbiota that give rise to SCFA. Propionic and butyric acids have been found to play an important role in... 
Lipopolysaccharide-binding protein | Succinic acid | Akkermansia | Amino acids | SCFA | Whole-grain barley | ACID | BETA-GLUCAN | FIBER COMPONENTS | CHOLESTEROL | AKKERMANSIA-MUCINIPHILA | SERUM | OAT BRAN | NUTRITION & DIETETICS | RESISTANT STARCH | GLUCOSE | INDUCED OBESITY | Intestinal Mucosa - metabolism | Rats, Wistar | Diet, High-Fat - adverse effects | Gastroenteritis - microbiology | Male | Cecum - microbiology | Gram-Negative Bacteria - metabolism | Hordeum - chemistry | Gram-Negative Bacteria - immunology | Gram-Negative Bacteria - isolation & purification | Fatty Acids, Volatile - metabolism | Liver - immunology | Dietary Fiber - therapeutic use | Cecum - metabolism | Intestinal Mucosa - immunology | Seeds - chemistry | Gram-Positive Bacteria - growth & development | Gram-Positive Bacteria - immunology | Gastroenteritis - immunology | Hyperlipidemias - immunology | Seeds - metabolism | Hyperlipidemias - metabolism | Hordeum - metabolism | Liver - metabolism | Inflammation Mediators - blood | Dietary Fiber - metabolism | Intestinal Mucosa - microbiology | Random Allocation | Fermentation | Gastroenteritis - prevention & control | Hyperlipidemias - prevention & control | Diet, Fat-Restricted - adverse effects | beta-Glucans - therapeutic use | Hyperlipidemias - microbiology | Gram-Positive Bacteria - metabolism | beta-Glucans - metabolism | Animals | Gastroenteritis - metabolism | Gram-Negative Bacteria - growth & development | Gram-Positive Bacteria - isolation & purification | Cecum - immunology | Barley | Plasma | Diet | Metabolism | Rodents | Index Medicus | Näringslära | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Nutrition and Dietetics | Health Sciences
Journal Article
American Journal of Physiology-Gastrointestinal and Liver Physiology, ISSN 0193-1857, 12/2013, Volume 305, Issue 12, pp. G900 - G910
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2872 - 13
Journal Article
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 07/2014, Volume 94, Issue 9, pp. 1745 - 1752
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, pp. e0153607 - e0153607
Sepsis is characterized by inflammatory and metabolic alterations, which lead to massive cytokine production, oxidative stress and organ dysfunction. In severe... 
LIPID-METABOLISM | CECAL LIGATION | SIGNALING PATHWAY | PROLIFERATOR-ACTIVATED RECEPTORS | OLIVE OIL | MEDITERRANEAN DIET | NUCLEAR RECEPTORS | MULTIDISCIPLINARY SCIENCES | UNCOUPLING PROTEIN-2 | CRITICALLY-ILL PATIENTS | ENDOTOXIC-SHOCK | AMP-Activated Protein Kinases - metabolism | Carnitine O-Palmitoyltransferase - genetics | Fatty Acids, Monounsaturated - pharmacology | Reactive Oxygen Species - metabolism | Gene Expression - drug effects | Ion Channels - genetics | Male | Mitochondrial Proteins - genetics | Liver - physiopathology | Fatty Acids, Nonesterified - metabolism | Kidney - metabolism | Oleic Acid - pharmacology | Liver - drug effects | Mitochondrial Proteins - metabolism | Sepsis - metabolism | Carnitine O-Palmitoyltransferase - metabolism | Oxidation-Reduction - drug effects | Fatty Acids, Nonesterified - blood | Fatty Acids - metabolism | Kidney - physiopathology | Malondialdehyde - metabolism | Kidney - drug effects | Liver - metabolism | Survival Rate | Reverse Transcriptase Polymerase Chain Reaction | Sepsis - physiopathology | Blotting, Western | Sepsis - mortality | Animals | Ion Channels - metabolism | Survival Analysis | Mice | Uncoupling Protein 2 | AMP-Activated Protein Kinases - genetics | Care and treatment | Oleic acid | Sepsis | Research | Health aspects | Morbidity | Risk factors | Oxidative stress | Mitochondrial uncoupling protein 2 | Reactive oxygen species | Syngeneic grafts | Liver | Lung | Inflammatory response | mRNA | Kinases | AMP-activated protein kinase | Proteins | Receptors | Rodents | Oxidation | Pretreatment | Supplementation | Kidneys | AMP | Mortality | Cecum | Dietary supplements | Inflammation | Olive oil | Gene expression | Na+/K+-exchanging ATPase | Palmitoyltransferase | Body weight gain | Fatty acids | Esterification | Carnitine palmitoyltransferase | Carnitine | Immune systems | Injury prevention | Food intake | Plasma levels | Fats and oils | Kidney transplantation | Index Medicus
Journal Article