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1. Full Text Photocatalytic degradation of cefazolin over N-doped TiO.sub.2 under UV and sunlight irradiation: Prediction of the reaction paths via conceptual DFT
by Gurkan, Yelda Yalcin and Turkten, Nazli and Hatipoglu, Arzu and Cinar, Zekiye
Chemical Engineering Journal, ISSN 1385-8947, 03/2012, Volume 184, p. 113
Display Omitted 
Cefazolin
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2. Full Text Intracameral cefazolin during cataract surgery: Antibiotic choice in penicillin “allergic” patients
by Stevenson, Louis J and Cleary, Georgia
Clinical & Experimental Ophthalmology, ISSN 1442-6404, 08/2019, Volume 47, Issue 6, pp. 803 - 804
Cefazolin | Antibiotics | Surgery | Penicillin
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3. Full Text Increased 3-gram cefazolin dosing for cesarean delivery prophylaxis in obese women
by Swank, Morgan L., MD and Wing, Deborah A., MD and Nicolau, David P., PharmD and McNulty, Jennifer A., MD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2015, Volume 213, Issue 3, pp. 415.e1 - 415.e8
Objective The purpose of this study was to determine tissue concentrations of cefazolin after the administration of a 3-g prophylactic dose for cesarean... 
Obstetrics and Gynecology | minimal inhibitory concentration (MIC) | cesarean delivery | cefazolin | prophylaxis | obesity | SURGERY | PROJECT | SURGICAL SITE INFECTIONS | ANTIBIOTIC-PROPHYLAXIS | OBSTETRICS & GYNECOLOGY | Obesity | Prospective Studies | Cefazolin - therapeutic use | Drug Administration Schedule | Humans | Pregnancy Complications | Antibiotic Prophylaxis - methods | Treatment Outcome | Cefazolin - administration & dosage | Chromatography, High Pressure Liquid | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Pregnancy | Surgical Wound Infection - prevention & control | Anti-Bacterial Agents - therapeutic use | Cesarean Section | Anti-Bacterial Agents - pharmacokinetics | Subcutaneous Fat - chemistry | Adult | Female | Cefazolin - pharmacokinetics | Anti-Bacterial Agents - administration & dosage | Index Medicus | Abridged Index Medicus
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4. Full Text Antibiotic stability related to temperature variations in elastomeric pumps used for outpatient parenteral antimicrobial therapy (OPAT)
by Voumard, Rachel and Van Neyghem, Niklas and Cochet, Camille and Gardiol, Céline and Decosterd, Laurent and Buclin, Thierry and de Valliere, Serge
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 2017, Volume 72, Issue 5, pp. 1462 - 1465
Background: Elastomeric pumps can be used for the continuous administration of antimicrobials in the outpatient setting. A potentially limiting factor in their... 
INFECTIOUS DISEASES | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | Temperature | Cefepime | Infusion Pumps | Drug Stability | Floxacillin - chemistry | Humans | Piperacillin - chemistry | Cephalosporins - chemistry | Male | Healthy Volunteers | Cefazolin - metabolism | Anti-Bacterial Agents - chemistry | Female | Polymers | Cefazolin - chemistry | Index Medicus
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5. Full Text Population Pharmacokinetics of Cefazolin in Serum and Adipose Tissue From Overweight and Obese Women Undergoing Cesarean Delivery
by Grupper, Mordechai and Kuti, Joseph L and Swank, Morgan L and Maggio, Lindsay and Hughes, Brenna L and Nicolau, David P
The Journal of Clinical Pharmacology, ISSN 0091-2700, 06/2017, Volume 57, Issue 6, pp. 712 - 719
The optimal antibiotic prophylaxis dosing regimen of cefazolin for cesarean delivery (CD) in overweight and obese women is unknown. This study was done to... 
pharmacokinetics | prophylaxis | obesity | Monte Carlo simulation | surgery | INFECTIONS | HUMANS | MORBIDLY OBESE | PHARMACOLOGY & PHARMACY | PROPHYLACTIC CEFAZOLIN | Anti-Bacterial Agents - blood | Cefazolin - blood | Humans | Antibiotic Prophylaxis | Microbial Sensitivity Tests | Pregnancy | Young Adult | Adipose Tissue - metabolism | Cesarean Section | Overweight - metabolism | Overweight - blood | Models, Biological | Anti-Bacterial Agents - pharmacokinetics | Adult | Female | Cefazolin - pharmacokinetics | Monte Carlo Method | Overweight persons | Usage | Cefazolin | Analysis | Dosage and administration | Pharmacokinetics | Health aspects | Cesarean section | Obesity | Index Medicus
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6. Full Text 3D printed Polycaprolactone scaffolds with dual macro-microporosity for applications in local delivery of antibiotics
by Visscher, Luke E and Dang, Hoang Phuc and Knackstedt, Mark A and Hutmacher, Dietmar W and Tran, Phong A
Materials Science & Engineering C, ISSN 0928-4931, 06/2018, Volume 87, pp. 78 - 89
Advanced scaffolds used in tissue regenerating applications should be designed to address clinically relevant complications such as surgical site infection... 
Infection | 3D printing, medical grade PCL | Antibiotic | Elution | Biodegradable polymer | Prophylaxis | INFECTIONS | MATERIALS SCIENCE, BIOMATERIALS | RECONSTRUCTION | TISSUE | CONTROLLED-RELEASE | BREAST IMPLANT | CEFAZOLIN | FABRICATION | AGENTS | Cefazolin - pharmacology | Polyesters - pharmacology | Polyesters - chemistry | Animals | Anti-Bacterial Agents - pharmacokinetics | Anti-Bacterial Agents - pharmacology | Cefazolin - pharmacokinetics | Mice | Printing, Three-Dimensional | Staphylococcus aureus - growth & development | Drug Delivery Systems - methods | 3T3 Cells | Cefazolin - chemistry | Blood coagulation | Drug delivery systems | Complications | Tissue engineering | Mechanical properties | Cytotoxicity | Drug delivery | Biopolymers | 3-D printers | Leaching | Biological activity | Regeneration | Microporosity | Three dimensional printing | Cefazolin | Antibiotics | Surgery | Fibroblasts | Porosity | Surface area | Polycaprolactone | Scaffolds | Index Medicus
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7. Full Text Clinical on-site monitoring of ß-lactam antibiotics for a personalized antibiotherapy
by Bruch, R and Chatelle, C and Kling, A and Rebmann, B and Wirth, S and Schumann, S and Weber, W and Dincer, C and Urban, G
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 3127 - 10
An appropriate antibiotherapy is crucial for the safety and recovery of patients. Depending on the clinical conditions of patients, the required dose to... 
Microfluidic Analytical Techniques | beta-Lactams - pharmacokinetics | Anti-Bacterial Agents - blood | Piperacillin - blood | Cefazolin - blood | Point-of-Care Testing | Humans | Piperacillin - pharmacokinetics | Male | Cefazolin - administration & dosage | Cefuroxime - blood | Drug Monitoring - methods | Piperacillin - administration & dosage | beta-Lactams - blood | Cefuroxime - pharmacokinetics | Anti-Bacterial Agents - pharmacokinetics | Drug Monitoring - instrumentation | Female | Cefazolin - pharmacokinetics | Cefuroxime - administration & dosage | Anti-Bacterial Agents - administration & dosage | beta-Lactams - administration & dosage | Precision Medicine | Cefuroxime | Penicillin-binding protein | Cefazolin | Cephalosporins | Antibiotics | Piperacillin | Surgery | Penicillin | Pharmacokinetics | Blood levels | Index Medicus
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8. Full Text Optimal Cefazolin Prophylactic Dosing for Bariatric Surgery: No Need for Higher Doses or Intraoperative Redosing
by Chen, Xing and Brathwaite, Collin E. M and Barkan, Alexander and Hall, Keneth and Chu, Gloria and Cherasard, Patricia and Wang, Shan and Nicolau, David P and Islam, Shahidul and Cunha, Burke A
Obesity Surgery, ISSN 0960-8923, 3/2017, Volume 27, Issue 3, pp. 626 - 629
The goal of this pharmacokinetic (PK) study was to evaluate whether a single 2-g prophylactic dose of cefazolin given (IV) bolus provides effective protective... 
Antibiotic intraoperative redosing | Surgical antibiotic prophylaxis | Cefazolin pharmacokinetics | Medicine & Public Health | Surgery | SURGERY | MORBIDLY OBESE-PATIENTS | Obesity, Morbid - surgery | Humans | Middle Aged | Antibiotic Prophylaxis - methods | Male | Calibration | Cefazolin - administration & dosage | Obesity, Morbid - drug therapy | Antibiotic Prophylaxis - standards | Dose-Response Relationship, Drug | Surgical Wound Infection - prevention & control | Drug Dosage Calculations | Intraoperative Care - methods | Anti-Bacterial Agents - pharmacokinetics | Adult | Female | Staphylococcal Infections - prevention & control | Cefazolin - pharmacokinetics | Bariatric Surgery - adverse effects | Staphylococcus aureus - drug effects | Anti-Bacterial Agents - administration & dosage | Obesity, Morbid - metabolism | Obesity | Medical colleges | Cefazolin | Resveratrol | Skin | High performance liquid chromatography | Bacterial infections | Gastrointestinal surgery | Preventive medicine | Antibiotics | Drug therapy | Index Medicus
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9. Full Text Quantification of cefazolin in serum and adipose tissue by ultra high performance liquid chromatography-Tandem mass spectrometry (UHPLC–MS/MS): application to a pilot study of obese women undergoing cesarean delivery
by Lillico, Ryan and Sayre, Casey L and Sitar, Daniel S and Davies, Neal M and Baron, Cynthia M and Lakowski, Ted M
Journal of Chromatography B, ISSN 1570-0232, 09/2016, Volume 1031, pp. 94 - 98
Higher doses of cefazolin are required in obese patients for preoperative antibiotic prophylaxis, owing to its low lipophilicity. An ultra high performance... 
Cesarean delivery | Cefazolin | Adipose tissue | Mass spectrometry | Stable-isotope internal standard | SURGERY | CHEMISTRY, ANALYTICAL | ANTIBIOTICS | HUMAN PLASMA | BIOCHEMICAL RESEARCH METHODS | PROPHYLACTIC CEFAZOLIN | PREGNANCY | PARTURIENTS | PHARMACOKINETICS | Anti-Bacterial Agents - blood | Chromatography, High Pressure Liquid - methods | Cefazolin - blood | Humans | Anti-Bacterial Agents - metabolism | Obesity - blood | Obesity - metabolism | Pregnancy | Adipose Tissue - metabolism | Cesarean Section | Pilot Projects | Cefazolin - metabolism | Adult | Female | Adipose Tissue - chemistry | Tandem Mass Spectrometry - methods | Adipose tissues | Women | Obesity | Pharmacy | Drugstores | High performance liquid chromatography | Cesarean section | Index Medicus
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10. Full Text Microbiological Aetiology, Epidemiology, and Clinical Profile of Prosthetic Joint Infections: Are Current Antibiotic Prophylaxis Guidelines Effective?
by Trisha N. Peel and Allen C. Cheng and Kirsty L. Buising and Peter F. M. Choong
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2012, Volume 56, Issue 5, pp. 2386 - 2391
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
SURGERY | REPLACEMENT | TOTAL HIP-ARTHROPLASTY | BLIND RANDOMIZED TRIAL | IMPACT | VANCOMYCIN | THERAPY | KNEE ARTHROPLASTY | PREVENTION | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | CEFAZOLIN | Joint Prosthesis - microbiology | Glycopeptides - administration & dosage | Humans | Drug Resistance, Bacterial | Male | Antibiotic Prophylaxis | Enterococcus - physiology | Anti-Bacterial Agents - therapeutic use | Prosthesis-Related Infections - microbiology | Female | Retrospective Studies | Gram-Negative Bacteria - physiology | Methicillin-Resistant Staphylococcus aureus - physiology | Prosthesis-Related Infections - epidemiology | Cefazolin - therapeutic use | Methicillin-Resistant Staphylococcus aureus - drug effects | Arthroplasty | Cefazolin - administration & dosage | Australia - epidemiology | Knee - microbiology | Glycopeptides - therapeutic use | Gram-Negative Bacteria - drug effects | Prosthesis-Related Infections - prevention & control | Knee - surgery | Aged | Enterococcus - drug effects | Hip - surgery | Hip - microbiology | Anti-Bacterial Agents - administration & dosage | Practice Guidelines as Topic | Index Medicus | Pathogens | Prophylaxis | Drug resistance | Joint diseases | Epidemiology | Infection | Gram-negative bacilli | Microorganisms | Cefazolin | Hospitals | Antibiotics | Etiology | Glycopeptides | Prosthetics | Epidemiology and Surveillance
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11. Full Text Effect of dual delivery of antibiotics (vancomycin and cefazolin) and BMP-7 from chitosan microparticles on Staphylococcus epidermidis and pre-osteoblasts in vitro
by Mantripragada, Venkata P and Jayasuriya, Ambalangodage C
Materials Science & Engineering C, ISSN 0928-4931, 10/2016, Volume 67, pp. 409 - 417
The main aims of this manuscript are to: i) determine the effect of commonly used antibiotics to treat osteoarticular infections on osteoblast viability, ii)... 
Osteoblast | BMP-7 | Chitosan microparticles | Cefazolin | Staphylococcus epidermidis | Vancomycin | MATERIALS SCIENCE, BIOMATERIALS | PENETRATION | RELEASE | MODEL | IMPLANTS | OSTEOMYELITIS | BLEND | BONE-GRAFTS | GROWTH | INFECTION | SCAFFOLDS | Bone Morphogenetic Protein 7 - pharmacokinetics | Cefazolin - pharmacology | Bone Morphogenetic Protein 7 - chemistry | Humans | Delayed-Action Preparations - chemistry | Vancomycin - chemistry | Staphylococcus epidermidis - growth & development | Vancomycin - pharmacokinetics | Anti-Bacterial Agents - chemistry | Delayed-Action Preparations - pharmacology | Vancomycin - pharmacology | Anti-Bacterial Agents - pharmacokinetics | Delayed-Action Preparations - pharmacokinetics | Anti-Bacterial Agents - pharmacology | Cefazolin - pharmacokinetics | Osteoblasts - cytology | Osteoblasts - metabolism | Bone Morphogenetic Protein 7 - pharmacology | Cefazolin - chemistry | Analysis | Index Medicus | Biomedical materials | Antibiotics | Bacteria | Biocompatibility | In vitro testing | Chitosan | Microparticles
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12. Full Text Cefazolin Prophylaxis in Obese Women Undergoing Cesarean Delivery A Randomized Controlled Trial
by Maggio, L and Nicolau, DP and DaCosta, M and Rouse, DJ and Hughes, BL
OBSTETRICS AND GYNECOLOGY, ISSN 0029-7844, 05/2015, Volume 125, Issue 5, pp. 1205 - 1210
OBJECTIVE: To compare adipose tissue concentration among obese women receiving 2 g compared with 3 g of precesarean cefazolin prophylaxis. METHODS: This was a... 
SURGERY | PENETRATION | ANTIBIOTIC-PROPHYLAXIS | OBSTETRICS & GYNECOLOGY | Body Mass Index | Cefazolin - therapeutic use | Double-Blind Method | Humans | Antibiotic Prophylaxis | Cefazolin - administration & dosage | Chromatography, High Pressure Liquid | Dose-Response Relationship, Drug | Surgical Wound Infection - prevention & control | Young Adult | Anti-Bacterial Agents - therapeutic use | Cesarean Section | Subcutaneous Fat - metabolism | Anti-Bacterial Agents - pharmacokinetics | Adult | Female | Cefazolin - pharmacokinetics | Anti-Bacterial Agents - administration & dosage | Index Medicus | Abridged Index Medicus
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13. Stability-Indicating Reverse Phase HPLC Method for the Determination of Cefazolin
by Lalitha, N and Sanjay, Pai P.N and Vyshak, M.G and Kadri, Uvesh
03/2010
Purpose: The aim of the present study was to establish the inherent stability of cefazolin through stress studies under a variety of ICH recommended test... 
Cefazolin | Reversed-phase HPLC | Stability-indicating assay
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14. Full Text Determination of total or free cefazolin and metronidazole in human plasma or interstitial fluid by HPLC-UV for pharmacokinetic studies in man
by Dorn, Christoph and Kratzer, Alexander and Schießer, Selina and Kees, Frieder and Wrigge, Hermann and Simon, Philipp
Journal of Chromatography B, ISSN 1570-0232, 06/2019, Volume 1118-1119, pp. 51 - 54
Cefazolin (CFZ) plus metronidazole (MTZ) is commonly used for perioperative antibiotic prophylaxis. An HPLC-UV method is described for the simultaneous... 
Tissue | Unbound fraction | Ultrafiltration | Microdialysis | Cephalosporin | Nitroimidazole | Extracellular Fluid - chemistry | Reproducibility of Results | Chromatography, High Pressure Liquid - methods | Cefazolin - blood | Humans | Metronidazole - blood | Linear Models | Spectrophotometry, Ultraviolet | Tissue Distribution | Metronidazole - pharmacokinetics | Sensitivity and Specificity | Metronidazole - chemistry | Cefazolin - pharmacokinetics | Cefazolin - chemistry | Phosphates | Emergency medicine | Pharmacy | Drugstores | Metronidazole | High performance liquid chromatography | Protein binding | Index Medicus
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15. Full Text Subcutaneous cefazolin to reduce surgical site infections in a porcine model
by Dubrovsky, Genia and Huynh, Nhan and Rouch, Joshua D and Koulakis, John P and Nicolau, David P and Sutherland, Christina A and Putterman, Seth and Dunn, James C.Y
Journal of Surgical Research, ISSN 0022-4804, 04/2018, Volume 224, pp. 156 - 159
Surgical site infections (SSIs) pose a significant health and financial burden. A key aspect of appropriate prophylaxis is the administration of antibiotics... 
Cefazolin | Surgical site infections | Pharmacokinetics | Subcutaneous | Prophylaxis | SURGERY | IMPACT | VANCOMYCIN | TISSUE | Surgical Wound Infection - prevention & control | Animals | Swine | Injections, Subcutaneous | Female | Cefazolin - pharmacokinetics | Cefazolin - administration & dosage | Anti-Bacterial Agents - administration & dosage | Disease Models, Animal | Index Medicus
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16. Full Text Pharmacokinetics and protein binding of cefazolin in morbidly obese patients
by van Kralingen, Simone and Taks, Margot and Diepstraten, Jeroen and van de Garde, Ewoudt M and van Dongen, Eric P and Wiezer, Marinus J and van Ramshorst, Bert and Vlaminckx, Bart and Deneer, Vera H and Knibbe, Catherijne A
European Journal of Clinical Pharmacology, ISSN 0031-6970, 10/2011, Volume 67, Issue 10, pp. 985 - 992
The aim of this study was to assess the pharmacokinetics and protein binding of cefazolin in morbidly obese patients undergoing bariatric surgery, to study the... 
Obesity | Biomedicine | Cefazolin | Antibiotics | Bariatric surgery | Morbid | Pharmacology/Toxicology | SURGERY | PROPHYLAXIS | AFFECT ANTIBIOTIC SERUM | PHARMACOLOGY & PHARMACY | INTRAOPERATIVE BLOOD-LOSS | TISSUE CONCENTRATIONS | Bariatric Surgery | Cefazolin - pharmacology | Anti-Bacterial Agents - blood | Injections, Intravenous | Prospective Studies | Age Factors | Cefazolin - blood | Obesity, Morbid - surgery | Humans | Male | Anti-Bacterial Agents - pharmacokinetics | Protein Binding | Adult | Female | Anti-Bacterial Agents - pharmacology | Cefazolin - pharmacokinetics | Obesity, Morbid - metabolism | Obesity, Morbid - blood | Analysis | Surgery | Staphylococcus aureus infections | Information management | Protein binding | Clinical trials | Pharmacology | Gastrointestinal surgery | Index Medicus
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17. Association between pre-operative Cefazolin dose and surgical site infection in obese patients
by Peppard, William J and Eberle, David G and Kugler, Nathan W and Mabrey, Danielle M and Weigelt, John A
Surgical Infections, ISSN 1096-2964, 05/2017, Volume 18, Issue 4, pp. 485 - 490
Background: A fixed dose of cefazolin results in serum concentrations that decrease as body mass increases. Current national guidelines suggest a pre-operative... 
pharmacokinetics | cefazolin | surgical site infection | SURGERY | INFECTIOUS DISEASES | MORBIDLY OBESE | ANTIBIOTIC-PROPHYLAXIS | Surgical Wound Infection - epidemiology | Cefazolin - therapeutic use | Obesity - complications | Humans | Middle Aged | Risk Factors | Male | Antibiotic Prophylaxis | Cefazolin - administration & dosage | Surgical Wound Infection - prevention & control | Anti-Bacterial Agents - therapeutic use | Surgical Wound Infection - drug therapy | Obesity - epidemiology | Anti-Bacterial Agents - pharmacokinetics | Adult | Female | Aged | Cefazolin - pharmacokinetics | Retrospective Studies | Anti-Bacterial Agents - administration & dosage | Surgical Wound Infection - complications
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