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Science, ISSN 0036-8075, 04/2017, Volume 356, Issue 6333, pp. 44 - 50
Viral infections have been proposed to elicit pathological processes leading to the initiation of T helper 1 (TH1) immunity against dietary gluten and celiac... 
CLASSICAL DENDRITIC CELLS | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | TISSUE | RISK | MICE | NATURAL-HISTORY | EXPRESSION | T-CELLS | REGULATORY FACTOR-I | CHILDREN | Glutens - immunology | Diet - adverse effects | Humans | Interferon Type I - immunology | Th1 Cells - immunology | Intestines - immunology | Celiac Disease - immunology | Intestines - virology | Receptor, Interferon alpha-beta - genetics | Disease Models, Animal | Reoviridae Infections - complications | Celiac Disease - virology | Reoviridae - genetics | Intestines - pathology | Interferon Regulatory Factor-1 - immunology | Mice, Inbred C57BL | Reoviridae Infections - immunology | Inflammation - virology | Immune Tolerance | Mice, Transgenic | Inflammation - immunology | Interferon Regulatory Factor-1 - genetics | Animals | Genetic Engineering | Interferon Type I - genetics | Antigens - immunology | Mice | Virus diseases | Celiac disease | Antigens | Complications and side effects | Causes of | Development and progression | Inflammation | Health aspects | Reoviruses | Ovalbumin | Immune response | Antibodies | Homeostasis | Viruses | Lymphocytes T | Infections | Small intestine | Conversion | Immunity | Diet | Lymphocytes | Interferon | Autoimmune diseases | Gluten | Viral infections | Immune system | Index Medicus | Government regulations | Tolerances
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2010, Volume 120, Issue 6, pp. 2131 - 2143
Enteropathy-associated T cell lymphoma is a severe complication of celiac disease (CD). One mechanism suggested to underlie its development is chronic exposure... 
INTESTINAL INFLAMMATION | RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | MOLECULAR TARGETS | NATURAL-KILLER-CELLS | INTERLEUKIN-15 | BCL-X | RECEPTOR | REFRACTORY SPRUE | CD8(+) T-CELLS | TRANSGENIC MICE | Phosphorylation | Apoptosis - drug effects | Enterocytes - metabolism | Humans | Intestines - metabolism | Leukemia - metabolism | STAT3 Transcription Factor - pharmacology | Interleukin-15 - immunology | Intestines - immunology | Inflammation - complications | Signal Transduction - immunology | Inflammation - metabolism | Lymphocytes - immunology | Celiac Disease - immunology | Leukemia - complications | Celiac Disease - complications | Adult | Janus Kinase 3 - metabolism | Intestine, Small - immunology | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Janus Kinase 3 - immunology | Lymphocytes - metabolism | Cytokines - metabolism | Inflammation - immunology | Protein Binding - immunology | Enterocytes - immunology | Interleukin-15 - pharmacology | Apoptosis - immunology | Signal Transduction - drug effects | Leukemia - immunology | Interleukin-15 - metabolism | Intestine, Small - metabolism | STAT3 Transcription Factor - immunology | Celiac Disease - metabolism | Cytokines - pharmacology | Care and treatment | Lymphocytes | Development and progression | Interleukin-15 | Inflammation | Non-Hodgkin's lymphomas | T cells | Properties | Health aspects | Index Medicus | Abridged Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2012, Volume 18, Issue 3, pp. 441 - 445
Celiac disease is an immune-mediated disorder in which mucosal autoantibodies to the enzyme transglutaminase 2 (TG2)(1) are generated in response to the... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GERMINAL-CENTER | CELL BIOLOGY | MEMORY B-CELLS | PEPTIDES | AFFINITY | IMMUNE-RESPONSES | HUMAN MONOCLONAL-ANTIBODIES | TISSUE TRANSGLUTAMINASE | ASSOCIATION | RAPID GENERATION | ANTIGEN | Glutens - immunology | Immunoglobulin G - blood | Autoantibodies - blood | Humans | Transglutaminases - blood | Immunoglobulin M - immunology | HLA-DQ Antigens - immunology | Immunoglobulin D - immunology | Transglutaminases - immunology | Celiac Disease - immunology | Immunoglobulin G - immunology | Intestinal Mucosa - immunology | Intestinal Mucosa - enzymology | Escherichia coli - metabolism | Celiac Disease - blood | Plasma Cells - metabolism | Single-Cell Analysis | Somatic Hypermutation, Immunoglobulin | GTP-Binding Proteins - immunology | Autoantibodies - immunology | Immunoglobulin D - blood | Antibody-Producing Cells - immunology | B-Lymphocytes - immunology | Immunoglobulin M - blood | GTP-Binding Proteins - blood | Escherichia coli - genetics | Immunoglobulin A - immunology | Transglutaminases - metabolism | Immunoglobulin A - blood | Mutation | GTP-Binding Proteins - metabolism | Plasma Cells - immunology | Immune response | Gastrointestinal diseases | Colorectal diseases | Plasma cells | Physiological aspects | Genetic aspects | Research | Gluten | Health aspects | Risk factors | Celiac disease | Antigens | Enzymes | Cellular biology | Gene expression | Immune system | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7337, pp. 220 - 224
Under physiological conditions the gut-associated lymphoid tissues not only prevent the induction of a local inflammatory immune response, but also induce... 
TGF-BETA | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | CLASS-I | ORAL TOLERANCE | MAJOR HISTOCOMPATIBILITY COMPLEX | DIFFERENTIATION | GLUTEN SENSITIVITY | CELIAC-DISEASE | BOWEL-DISEASE | TRANSGENIC MICE | Glutens - immunology | Coculture Techniques | Dendritic Cells - immunology | Humans | Middle Aged | Child, Preschool | T-Lymphocytes, Regulatory - immunology | Young Adult | Forkhead Transcription Factors - metabolism | Intestinal Mucosa - immunology | Phosphorylation - drug effects | Child | Interleukin-12 - secretion | Interleukin-12 - biosynthesis | Tretinoin - pharmacology | Celiac Disease - chemically induced | Administration, Oral | Mitogen-Activated Protein Kinase 8 - metabolism | Mice, Transgenic | Interleukin-23 - immunology | T-Lymphocytes, Regulatory - drug effects | Diet | Dendritic Cells - enzymology | Glutens - administration & dosage | Adolescent | Interleukin-12 - immunology | Mice | Receptors, Interleukin-12 - deficiency | T-Lymphocytes, Regulatory - metabolism | Adjuvants, Immunologic - pharmacology | Interleukin-15 - immunology | HLA-DQ Antigens - immunology | Celiac Disease - etiology | Intestinal Mucosa - cytology | Celiac Disease - immunology | T-Lymphocytes, Regulatory - cytology | Adult | Dendritic Cells - drug effects | Interleukin-23 - secretion | Dendritic Cells - metabolism | Immune Tolerance - drug effects | Gliadin - immunology | Mice, Inbred C57BL | Cells, Cultured | Tretinoin - immunology | Inflammation - immunology | Animals | Gliadin - administration & dosage | Interleukin-15 - genetics | HLA-DQ Antigens - genetics | Physiological aspects | Antigens | Immune response | Research | Health aspects | Tretinoin | Proteins | Celiac disease | Immunology | Rodents | Index Medicus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 413 - 422
Background Thymic stromal lymphopoietin (TSLP) is a cytokine with pleiotropic functions in the immune system. It has been associated with allergic reactions in... 
Allergy and Immunology | Thymic stromal lymphopoietin | gut homeostasis | celiac disease | anti-inflammatory drugs | atopic dermatitis | ulcerative colitis | skin homeostasis | DENDRITIC CELLS | TSLP | INDUCE | RECEPTOR | IMMUNOLOGY | ATOPIC-DERMATITIS | POLYMORPHISMS | EPITHELIAL-CELLS | ALLERGY | ASTHMA | NF-KAPPA-B | EXPRESSION | Dermatitis, Atopic - genetics | Skin - microbiology | Dendritic Cells - immunology | Humans | Salmonella Infections - genetics | Colitis, Ulcerative - genetics | Salmonella Infections - immunology | Dendritic Cells - pathology | Dermatitis, Atopic - microbiology | Colitis, Ulcerative - immunology | Case-Control Studies | Intestines - immunology | Celiac Disease - microbiology | Escherichia coli Infections - genetics | Celiac Disease - immunology | Leukocytes, Mononuclear - immunology | Dermatitis, Atopic - immunology | Female | Cytokines - genetics | Leukocytes, Mononuclear - microbiology | Skin - pathology | Cytokines - immunology | Disease Models, Animal | Skin - immunology | Salmonella Infections - pathology | Intestines - pathology | Celiac Disease - genetics | Gene Expression Regulation - immunology | Escherichia coli - immunology | Escherichia coli Infections - microbiology | Colitis, Ulcerative - pathology | Dermatitis, Atopic - pathology | Celiac Disease - pathology | Leukocytes, Mononuclear - pathology | Salmonella - immunology | Animals | Intestines - microbiology | Colitis, Ulcerative - microbiology | Escherichia coli Infections - pathology | Dendritic Cells - microbiology | Escherichia coli Infections - immunology | Salmonella Infections - microbiology | Mice | Protein Isoforms - immunology | Protein Isoforms - genetics | Skin | Salmonella | Food allergies | Antigens | Inflammation | Inflammatory diseases | Asthma | Inflammatory bowel disease | E coli | Biopsy | Lymphocytes | Rodents | Software | Laboratory animals | Index Medicus | Abridged Index Medicus | moDC, Monocyte-derived dendritic cell | NF-κB, Nuclear factor κB | TLR, Toll-like receptor | AD, Atopic dermatitis | STAT5, Signal transducer and activator of transcription 5 | mDC, Myeloid dendritic cell | shTSLP, Short isoform thymic stromal lymphopoietin | UC, Ulcerative colitis | CD, Celiac disease | DSS, Dextran sodium sulfate | DC, Dendritic cell | poly I:C, Polyinosinic:polycytidylic acid | TSLP, Thymic stromal lymphopoietin | MAPK, Mitogen-activated protein kinase | lTSLP, Long isoform thymic stromal lymphopoietin | TSLPR, Thymic stromal lymphopoietin receptor | Mechanisms of Allergy and Clinical Immunology
Journal Article
Immunity, ISSN 1074-7613, 09/2016, Volume 45, Issue 3, pp. 610 - 625
Journal Article
Science, ISSN 0036-8075, 11/2015, Volume 350, Issue 6262, pp. 830 - 834
In healthy individuals, the intestinal microbiota cannot access the liver, spleen, or other peripheral tissues. Some pathogenic bacteria can reach these sites,... 
ORAL TOLERANCE | DENDRITIC CELLS | BLOOD-BRAIN-BARRIER | MULTIDISCIPLINARY SCIENCES | Genomic Islands - immunology | Spleen - immunology | Humans | Antigens, Bacterial - immunology | Salmonella Infections - immunology | Capillary Permeability - immunology | Antigens, Bacterial - blood | Ileum - immunology | Type III Secretion Systems - genetics | Intestines - immunology | Type III Secretion Systems - immunology | Ileum - blood supply | Celiac Disease - microbiology | Liver - immunology | Celiac Disease - immunology | Intestinal Mucosa - immunology | Celiac Disease - blood | Intestines - blood supply | Wnt Signaling Pathway | Genomic Islands - genetics | Microbiota - immunology | Salmonella typhimurium - genetics | Salmonella typhimurium - immunology | Salmonella typhimurium - pathogenicity | Signal Transduction | Mice, Inbred C57BL | Intestinal Mucosa - microbiology | beta Catenin - metabolism | Animals | Intestines - microbiology | Transaminases - blood | Mice | Ileum - microbiology | Immune response | Research | Microbiota (Symbiotic organisms) | Health aspects | Bacteria | Cellular biology | Liver | Veins & arteries | Index Medicus | Salmonella | Barriers | Secretions | Islands | Patients | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Gastroenterology and Hepatology | Gastroenterologi
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, pp. e24092 - e24092
We present immunological data from two clinical trials where the effect of experimental human hookworm (Necator americanus) infection on the pathology of... 
CYTOKINES | GLIADIN | NECATOR-AMERICANUS | EXPANSION | BIOLOGY | REGULATORY T-CELLS | PARASITE INFECTION | ETHIOPIA | INTERLEUKIN-10 |