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Journal Article
Immunologic Research, ISSN 0257-277X, 10/2011, Volume 51, Issue 1, pp. 45 - 60
Complement system activation plays an important role in both innate and acquired immunity. Activation of the complement and the subsequent formation of C5b-9... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | ACTIVATED PROTEIN-KINASE | SYSTEMIC LUPUS-ERYTHEMATOSUS | GUILLAIN-BARRE-SYNDROME | ULCERATIVE-COLITIS | GLOMERULAR EPITHELIAL-CELLS | C5B-9 COMPLEX | IMMUNOLOGY | S-PROTEIN | MANNAN-BINDING LECTIN | ACUTE MYOCARDIAL-INFARCTION | SMOOTH-MUSCLE-CELLS | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2013, Volume 14, Issue 2, pp. 179 - 185
The innate immune system senses viral DNA that enters mammalian cells, or in aberrant situations self-DNA, and triggers type I interferon production. Here we... 
AICARDI-GOUTIERES-SYNDROME | INTRACELLULAR DNA | NUCLEIC-ACID | PATHWAY | RIG-I | MUTATIONS | IMMUNOLOGY | PROTEINS | EXONUCLEASE TREX1 | AUTOIMMUNE-DISEASE | CELL-DEATH | Phosphoproteins - immunology | HMGB2 Protein - genetics | RNA, Small Interfering - genetics | Small Molecule Libraries - pharmacology | Dendritic Cells - immunology | Humans | Cytosol - drug effects | Cell Cycle Proteins - antagonists & inhibitors | Signal Transduction - immunology | Cell Cycle Proteins - immunology | HIV-1 - physiology | ATP-Binding Cassette Transporters - genetics | HSP90 Heat-Shock Proteins - immunology | Cell Cycle Proteins - genetics | Dendritic Cells - drug effects | HSP90 Heat-Shock Proteins - genetics | Dendritic Cells - virology | Nuclear Proteins - genetics | Fibroblasts - virology | Gene Expression Regulation - immunology | Gene Silencing | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Phosphoproteins - genetics | Chaperonins - immunology | Immunity, Innate | Nuclear Proteins - immunology | Cytosol - virology | Gene Expression Regulation - drug effects | HMGB2 Protein - immunology | DNA, Viral - immunology | Animals | Signal Transduction - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Fibroblasts - drug effects | Proteomics | Cytosol - metabolism | Fibroblasts - immunology | Protein-Serine-Threonine Kinases - immunology | Mice | DNA, Viral - genetics | ATP-Binding Cassette Transporters - immunology | Chaperonins - genetics | Vesiculovirus - physiology | Chaperonins - antagonists & inhibitors | Retrovirus infections | Heat shock proteins | Physiological aspects | Natural immunity | Genetic aspects | Research | Health aspects | Risk factors
Journal Article
Immunity, ISSN 1074-7613, 10/2009, Volume 31, Issue 4, pp. 551 - 564
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 50, pp. 19855 - 19860
To ensure survival in the face of genomic insult, cells have evolved complex mechanisms to respond to DNA damage, termed the DNA damage checkpoint. The... 
Phosphorylation | Transcriptional regulatory elements | Chromatin | DNA replication | DNA damage | DNA | Cell lines | Cell cycle | Antibodies | Regulatory sequences | Mass spectrometry | MOTIFS | CHK1 | MULTIDISCIPLINARY SCIENCES | mass spectrometry | PROTEIN-PHOSPHORYLATION | phosphorylation | DNA-DAMAGE-RESPONSE | ATAXIA-TELANGIECTASIA | EXPRESSION | CHECKPOINTS | ATR | Protein-Serine-Threonine Kinases - deficiency | Immunoprecipitation | Humans | Phosphopeptides - immunology | Amino Acid Motifs - radiation effects | DNA-Binding Proteins - metabolism | Cell Cycle Proteins - immunology | Ultraviolet Rays | DNA Damage - physiology | Signal Transduction - radiation effects | Protein-Serine-Threonine Kinases - metabolism | Cell Line | DNA-Binding Proteins - physiology | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - immunology | Protein-Serine-Threonine Kinases - physiology | Cell Cycle Proteins - metabolism | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | Substrate Specificity - genetics | Tumor Suppressor Proteins - immunology | Amino Acid Motifs - physiology | Tumor Suppressor Proteins - physiology | Phosphorylation - radiation effects | Substrate Specificity - radiation effects | Cell Line, Tumor | Protein-Serine-Threonine Kinases - immunology | Signal Transduction - physiology | Phosphopeptides - physiology | Amino Acid Motifs - genetics | Cell Cycle Proteins - physiology | DNA Damage - radiation effects | Phosphopeptides - isolation & purification | Physiological aspects | Causes of | Research | Biological Sciences
Journal Article