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Immunological reviews, ISSN 0105-2896, 2011, Volume 243, Issue 1, pp. 206 - 214
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2015, Volume 195, Issue 9, pp. 4514 - 4523
Granzyme B (GzmB) has previously been shown to be critical for CD8(+) T cell-mediated graft-versus-host disease (GVHD) but dispensable for GVHD mediated by... 
APOPTOSIS | IMMUNITY | PATHWAY | BONE-MARROW-TRANSPLANTATION | REJECTION | INJURY | PERFORIN | MECHANISMS | IMMUNOLOGY | SUPPRESSION | CYTOTOXICITY | Spleen - immunology | Cell Death - immunology | Granzymes - genetics | Mice, 129 Strain | Bone Marrow Transplantation - methods | Graft vs Host Disease - immunology | Cell Movement - genetics | Gastrointestinal Tract - pathology | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Gastrointestinal Tract - immunology | Graft vs Host Disease - genetics | Lymphocyte Activation - immunology | Flow Cytometry | Cell Death - genetics | Inflammation Mediators - metabolism | CD8-Positive T-Lymphocytes - metabolism | Granzymes - immunology | Graft vs Host Disease - etiology | Cytokines - immunology | Inflammation Mediators - immunology | Acute Disease | Cell Proliferation - genetics | Cytokines - metabolism | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Histocompatibility - genetics | Spleen - cytology | Histocompatibility - immunology | Gastrointestinal Tract - metabolism | Mice, Knockout | Granzymes - deficiency | Animals | Spleen - metabolism | Bone Marrow Transplantation - adverse effects | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Cell Movement/genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Cytokines/immunology | Immunologi inom det medicinska området | CD8-Positive T-Lymphocytes/immunology | Cell Death/genetics | Granzymes/deficiency | Inflammation Mediators/immunology | Cell Proliferation/genetics | Immunology in the medical area | Spleen/cytology | Bone Marrow Transplantation/adverse effects | Graft vs Host Disease/etiology | Basic Medicine | Histocompatibility/genetics | CD4-Positive T-Lymphocytes/immunology | Lymphocyte Activation/immunology | Medicinska och farmaceutiska grundvetenskaper | Gastrointestinal Tract/immunology
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2015, Volume 43, Issue 3, pp. 451 - 462
Endoplasmic reticulum (ER) stress is observed in many human diseases, often associated with inflammation. ER stress can trigger inflammation through... 
LISTERIA-MONOCYTOGENES | CYTOCHROME-C | MESSENGER-RNA | BRUCELLA-ABORTUS | INDUCED APOPTOSIS | ER STRESS | THIOREDOXIN-INTERACTING PROTEIN | SECRETION | IMMUNOLOGY | TRANSCRIPTION FACTOR | CELL-DEATH | Caspase 2 - genetics | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Brucella abortus - physiology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | BH3 Interacting Domain Death Agonist Protein - genetics | Caspase 2 - metabolism | Mitochondria - immunology | Endoplasmic Reticulum Stress - genetics | Endoplasmic Reticulum Stress - immunology | Caspase 2 - immunology | Host-Pathogen Interactions - immunology | DNA-Binding Proteins - metabolism | Mitochondria - genetics | Brucella abortus - immunology | Interleukin-1beta - metabolism | Reactive Oxygen Species - immunology | HEK293 Cells | Transcription Factors - immunology | BH3 Interacting Domain Death Agonist Protein - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Protein-Serine-Threonine Kinases - metabolism | RNA Interference - immunology | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-1beta - immunology | Mitochondria - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Regulatory Factor X Transcription Factors | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | BH3 Interacting Domain Death Agonist Protein - immunology | Protein-Serine-Threonine Kinases - immunology | Endoribonucleases - immunology | Medical colleges | Stress (Physiology) | Mitochondrial DNA | Analysis | Cytochrome | Bacterial infections | Dehydrogenases | Infections | Inflammation | Proteins | Studies | Mitochondria | Rodents | Ligands | Endoplasmic reticulum | Deoxyribonucleic acid--DNA | Apoptosis
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2016, Volume 113, Issue 1, pp. 212 - 217
Journal Article
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 343, Issue 6169, pp. 428 - 432
Journal Article
Immunologic research, ISSN 1559-0755, 2011, Volume 51, Issue 1, pp. 45 - 60
...) on the cell membranes lead to cell death. However, when the number of channels assembled on the surface of nucleated cells is limited, sublytic C5b-9 can induce cell cycle progression by activating signal transduction pathways... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | ACTIVATED PROTEIN-KINASE | SYSTEMIC LUPUS-ERYTHEMATOSUS | GUILLAIN-BARRE-SYNDROME | ULCERATIVE-COLITIS | GLOMERULAR EPITHELIAL-CELLS | C5B-9 COMPLEX | IMMUNOLOGY | S-PROTEIN | MANNAN-BINDING LECTIN | ACUTE MYOCARDIAL-INFARCTION | SMOOTH-MUSCLE-CELLS | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
Blood, ISSN 1528-0020, 2013, Volume 122, Issue 17, pp. 3062 - 3073
PD-L1 and PD-L2 expression were upregulated during GVHD, whereas PD-1/PD-L1 was more critical than PD-1/PD-L2 in downregulating GVHD. Our data provide new... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | BONE-MARROW-TRANSPLANTATION | T-CELL-ACTIVATION | GASTROINTESTINAL-TRACT | ENDOTHELIAL-CELLS | IN-VIVO | TNF-ALPHA | HEMATOLOGY | PD-1 | GAMMA-DEPENDENT MECHANISM | LYMPHOCYTES | Glucose Transport Proteins, Facilitative - metabolism | Liver - pathology | Cell Proliferation | Spleen - immunology | Programmed Cell Death 1 Ligand 2 Protein - metabolism | Intestines - metabolism | Graft vs Host Disease - metabolism | CD4-Positive T-Lymphocytes - pathology | Graft vs Host Disease - immunology | Intestines - immunology | CD4-Positive T-Lymphocytes - immunology | Liver - immunology | Glucose Transport Proteins, Facilitative - immunology | Graft vs Host Disease - mortality | Bone Marrow Transplantation | Apoptosis Regulatory Proteins - genetics | Glucose Transport Proteins, Facilitative - genetics | Spleen - pathology | Transplantation Tolerance - immunology | Acute Disease | Apoptosis Regulatory Proteins - immunology | Intestines - pathology | Programmed Cell Death 1 Ligand 2 Protein - genetics | Liver - metabolism | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | Oxidative Phosphorylation | Programmed Cell Death 1 Receptor - metabolism | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Apoptosis Regulatory Proteins - metabolism | Graft vs Host Disease - pathology | Programmed Cell Death 1 Ligand 2 Protein - immunology | B7-H1 Antigen - metabolism | Animals | Spleen - metabolism | Peripheral Tolerance - immunology | Survival Analysis | Glycolysis | Mice | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Transplantation
Journal Article