X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (459408) 459408
Book Review (84038) 84038
Publication (57946) 57946
Book Chapter (5033) 5033
Newsletter (3621) 3621
Book / eBook (3223) 3223
Conference Proceeding (1903) 1903
Newspaper Article (1206) 1206
Dissertation (934) 934
Government Document (304) 304
Magazine Article (193) 193
Reference (184) 184
Web Resource (105) 105
Data Set (60) 60
Paper (33) 33
Trade Publication Article (32) 32
Streaming Video (10) 10
Journal / eJournal (9) 9
Presentation (7) 7
Transcript (4) 4
Report (2) 2
Streaming Audio (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (402310) 402310
animals (255464) 255464
humans (225224) 225224
mice (109629) 109629
apoptosis (105748) 105748
cell biology (105555) 105555
biochemistry & molecular biology (92769) 92769
male (90732) 90732
female (77952) 77952
neurosciences (69610) 69610
rats (66976) 66976
expression (59571) 59571
proteins (56595) 56595
cells, cultured (54099) 54099
analysis (49778) 49778
research (48833) 48833
cells (46361) 46361
cancer (45083) 45083
gene expression (43237) 43237
oxidative stress (42587) 42587
physiological aspects (40972) 40972
physiology (39309) 39309
article (38529) 38529
signal transduction (37808) 37808
activation (36647) 36647
cell line, tumor (34943) 34943
oncology (34542) 34542
cell death (32707) 32707
research article (32616) 32616
apoptosis - drug effects (32330) 32330
cell line (31945) 31945
immunology (31746) 31746
health aspects (28491) 28491
multidisciplinary sciences (28322) 28322
medicine (27881) 27881
inflammation (27644) 27644
mice, inbred c57bl (27526) 27526
rodents (27290) 27290
in-vitro (27179) 27179
apoptosis - physiology (27042) 27042
gene-expression (26162) 26162
biology (25608) 25608
cell-death (25280) 25280
neurons (24921) 24921
phosphorylation (24319) 24319
genetic aspects (24269) 24269
disease models, animal (23689) 23689
life sciences (23257) 23257
brain (23183) 23183
cell proliferation (23173) 23173
stem cells (22990) 22990
endocrinology & metabolism (22804) 22804
rats, sprague-dawley (22637) 22637
middle aged (22601) 22601
in-vivo (22559) 22559
adult (22453) 22453
immunohistochemistry (22177) 22177
biochemistry (22106) 22106
biophysics (21469) 21469
science (20650) 20650
genes (20341) 20341
time factors (20001) 20001
protein (19755) 19755
mutation (19658) 19658
pharmacology & pharmacy (19502) 19502
growth (19309) 19309
death (19076) 19076
neurology (18888) 18888
differentiation (18855) 18855
cell survival - drug effects (18579) 18579
inhibition (18464) 18464
kinases (18415) 18415
medicine, research & experimental (18128) 18128
mitochondria (17777) 17777
mice, knockout (17768) 17768
aged (17612) 17612
developmental biology (17105) 17105
abridged index medicus (16758) 16758
proliferation (16628) 16628
cell survival (16577) 16577
hematology (16560) 16560
metabolism (16551) 16551
biomedicine (16479) 16479
dose-response relationship, drug (16430) 16430
cell cycle (16336) 16336
signal transduction - physiology (16320) 16320
blotting, western (16290) 16290
care and treatment (15872) 15872
disease (15681) 15681
models, biological (15542) 15542
reactive oxygen species - metabolism (15174) 15174
enzymes (15150) 15150
neurons - metabolism (14890) 14890
cytokines (14774) 14774
rats, wistar (14668) 14668
nf-kappa-b (14650) 14650
gene (14558) 14558
tumors (14506) 14506
cell differentiation (14288) 14288
microbiology (14110) 14110
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (2006) 2006
UofT at Mississauga - Stacks (310) 310
UTL at Downsview - May be requested (249) 249
UofT at Scarborough - Stacks (188) 188
Online Resources - Online (175) 175
Earth Sciences (Noranda) - Stacks (156) 156
Collection Dvlpm't (Acquisitions) - Vendor file (129) 129
Collection Dvlpm't (Acquisitions) - Closed Orders (122) 122
Trinity College (John W Graham) - Stacks (33) 33
Engineering & Comp. Sci. - Stacks (30) 30
St. Michael's College (John M. Kelly) - 2nd Floor (24) 24
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (18) 18
UofT at Scarborough - Withdrawn (18) 18
Royal Ontario Museum - Stacks (17) 17
Chemistry (A D Allen) - Stacks (13) 13
UofT at Scarborough - May be requested in 6-10 wks (13) 13
Gerstein Science - Circulation Desk (12) 12
St. Michael's Hospital - Stacks (12) 12
Physics - Stacks (11) 11
Gerstein Science - Missing (9) 9
Dentistry (Harry R Abbott) - Stacks (7) 7
Victoria University E.J. Pratt - Stacks (7) 7
Earth Sciences (Noranda) - Missing (6) 6
Law (Bora Laskin) - Stacks (6) 6
Credit Valley Hospital - Reserve desk (5) 5
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (5) 5
Gerstein Science - Not Returned (5) 5
Gerstein Science - Periodical Stacks (5) 5
OISE - Stacks (5) 5
Robarts - Stacks (5) 5
St. Michael's College (John M. Kelly) - Circulation Desk (5) 5
Trinity College (John W Graham) - Storage (5) 5
Credit Valley Hospital - Stacks (4) 4
Mathematical Sciences - Stacks (4) 4
Media Commons - Microtexts (4) 4
Regis College - Stacks (4) 4
Trillium Health Centre - Reserve desk (4) 4
UofT at Mississauga - Reference (4) 4
Victoria University E.J. Pratt - Oversize (4) 4
Baycrest Hospital - Stacks (3) 3
Dentistry (Harry R Abbott) - Withdrawn (3) 3
Gerstein Science - Searching (3) 3
Gerstein Science - Theses (3) 3
Mt Sinai Hospital - Pathology (3) 3
New College (Ivey) - Stacks (3) 3
Providence Healthcare - Stacks (3) 3
St. Augustine's Seminary - Stacks (3) 3
St. Michael's Hospital - Circulation Desk (3) 3
Thomas Fisher Rare Book - Rare Book (3) 3
Toronto East General Hospital - Stacks (3) 3
Earth Sciences (Noranda) - Circulation Desk (2) 2
Engineering & Comp. Sci. - Reference (2) 2
Gerstein Science - Reference (2) 2
Holland Bloorview Kids Rehabilitation - Stacks (2) 2
Humber River Regional Hospital - Finch Stacks (2) 2
Markham Stouffville Hospital - Stacks (2) 2
Physics - New Books (2) 2
Providence Healthcare - Reference (2) 2
Scarborough Hospital - General (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Reference (2) 2
Trillium Health Centre - Stacks (2) 2
UofT Schools - Stacks (2) 2
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Collection Dvlpm't (Acquisitions) - Reference (1) 1
Credit Valley Hospital - Missing (1) 1
Dentistry (Harry R Abbott) - Circulation Desk (1) 1
Dentistry (Harry R Abbott) - May be requested (1) 1
Dentistry (Harry R Abbott) - Missing (1) 1
Earth Sciences (Noranda) - Oversize (1) 1
Earth Sciences (Noranda) - Reference (1) 1
Faculty of Information - Stacks (1) 1
Gerstein Science - Course Reserves (1) 1
Gerstein Science - Processing (1) 1
Gerstein Science - Reference Desk (1) 1
Gerstein Science - Reserve desk (1) 1
Humber River Regional Hospital - Church Stacks (1) 1
Knox College (Caven) - Stacks (1) 1
Missing (1) 1
OISE - Curriculum Resources (1) 1
Physics - Course Reserves (1) 1
Physics - Missing (1) 1
Providence Healthcare - Reserve desk (1) 1
Robarts - Processing (1) 1
Scarborough Hospital - Birchmount (1) 1
Scarborough Hospital - Closed Orders (1) 1
Scarborough Hospital - May be requested (1) 1
St Josephs Health Centre - General (1) 1
St. Michael's College (John M. Kelly) - 3rd Floor (1) 1
St. Michael's College (John M. Kelly) - Missing (1) 1
St. Michael's College (John M. Kelly) - Reference (1) 1
Sunnybrook Health Sciences Centre - Holland Reference (1) 1
Sunnybrook Health Sciences Centre - Online (1) 1
Toronto East General Hospital - Online (1) 1
Trinity College (John W Graham) - Reference (1) 1
UTL at Downsview - Stacks (1) 1
University College (Laidlaw) - Stacks (1) 1
UofT Schools - Special Collections (1) 1
UofT at Mississauga - Circulation Desk (1) 1
UofT at Mississauga - Missing (1) 1
UofT at Mississauga - Not returned (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (469845) 469845
Japanese (465) 465
French (285) 285
Chinese (270) 270
German (258) 258
Spanish (253) 253
Russian (249) 249
Polish (92) 92
Portuguese (25) 25
Dutch (24) 24
Czech (21) 21
Korean (20) 20
Italian (17) 17
Arabic (9) 9
Turkish (8) 8
Swedish (7) 7
Ukrainian (7) 7
Danish (6) 6
Finnish (6) 6
Hungarian (6) 6
Hebrew (5) 5
Lithuanian (3) 3
Norwegian (3) 3
Slovak (3) 3
Bulgarian (2) 2
Croatian (2) 2
Indonesian (2) 2
Romanian (2) 2
Serbian (2) 2
Afrikaans (1) 1
Latvian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 1760, Volume 459, Issue 3, pp. 513 - 524
BIK (BCL2-interacting killer) is a pro-apoptotic BH3 (BCL2 homology domain 3)-only protein and a member of the BCL2 protein family. It was proposed recently... 
BCL2-interacting killer (BIK) | Extracellularsignal-regulated kinase 1/2 (ERK1/2) | BCL2-interacting mediator of cell death (BIM) | Cell cycle | Apoptosis | Proteasome | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Neoplasms - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | G1 Phase - drug effects | Neoplasm Proteins - metabolism | Proto-Oncogene Proteins - biosynthesis | Proteolysis - drug effects | Ubiquitination - drug effects | Bcl-2-Like Protein 11 | RNA Interference | Apoptosis Regulatory Proteins - genetics | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Neoplasm Proteins - genetics | Apoptosis Regulatory Proteins - biosynthesis | Proto-Oncogene Proteins - metabolism | MAP Kinase Kinase 1 - antagonists & inhibitors | Proto-Oncogene Proteins - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Neoplasms - enzymology | Proteasome Endopeptidase Complex - chemistry | MAP Kinase Kinase 1 - metabolism | Proto-Oncogene Proteins - genetics | Cyclin-Dependent Kinase 6 - metabolism | MAP Kinase Kinase 2 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Apoptosis Regulatory Proteins - metabolism | Neoplasms - drug therapy | Membrane Proteins - biosynthesis | MAP Kinase Signaling System - drug effects | Membrane Proteins - antagonists & inhibitors | MAP Kinase Kinase 2 - antagonists & inhibitors | Protein Stability - drug effects | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Proteasome Endopeptidase Complex - metabolism | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12457 - 12466
Background: Most commercial TNF inhibitors are biomacromolecules. Results: A lead compound named C87 was identified using computer-aided drug design and could... 
RHEUMATOID-ARTHRITIS | Computer Modeling | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR SUPERFAMILY | Inflammation | CELL-DEATH | JNK ACTIVATION | PEPTIDOMIMETICS | Surface Plasmon Resonance (SPR) | AUTOIMMUNE-DISEASES | Cell Death | Tumor Necrosis Factor (TNF) | THERAPEUTIC TARGET | Cell Signaling | Small Molecules | TNF-ALPHA | BINDING | GALACTOSAMINE | Surface Plasmon Resonance | Tumor Necrosis Factor-alpha - metabolism | Small Molecule Libraries - pharmacology | Hepatitis, Animal - prevention & control | Humans | Hepatitis, Animal - genetics | Structure-Activity Relationship | Receptors, Tumor Necrosis Factor, Type I - metabolism | Dose-Response Relationship, Drug | Hepatitis, Animal - metabolism | Inflammation - metabolism | Caspases - metabolism | MAP Kinase Kinase 4 - metabolism | Protein Binding - drug effects | Molecular Structure | Disease Models, Animal | Cell Survival - drug effects | Jurkat Cells | Blotting, Western | Hydrazones - chemistry | Hydrazones - pharmacology | Small Molecule Libraries - chemistry | Tumor Necrosis Factor-alpha - pharmacology | Animals | Signal Transduction - drug effects | K562 Cells | Cell Line, Tumor | HL-60 Cells | Inflammation - genetics | Thiazoles - chemistry | Inflammation - prevention & control | Mice | Mice, Inbred BALB C | Thiazoles - pharmacology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | Immunology
Journal Article