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1. Full Text Anti‐adhesion activity of thyme (Thymus vulgaris L.) extract, thyme post‐distillation waste, and olive (Olea europea L.) leaf extract against Campylobacter jejuni on polystyrene and intestine epithelial cells
by Šikić Pogačar, Maja and Klančnik, Anja and Bucar, Franz and Langerholc, Tomaž and Smole Možina, Sonja
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 06/2016, Volume 96, Issue 8, pp. 2723 - 2730
BACKGROUND In order to survive in food‐processing environments and cause disease, Campylobacter jejuni requires specific survival mechanisms, such as biofilms,... 
Thymus vulgaris and Olea europea extracts | anti‐adhesion activity | waste material | abiotic/biotic surfaces | Campylobacter jejuni | Waste material | Thymus vulgaris and olea europea extracts | Abiotic/biotic surfaces | Anti-adhesion activity | ANTIOXIDANT ACTIVITY | ANTIBIOTICS | PRODUCTS | PHENOLIC-COMPOUNDS | FOOD SCIENCE & TECHNOLOGY | AGRICULTURE, MULTIDISCIPLINARY | anti-adhesion activity | CHEMISTRY, APPLIED | Plant Leaves - chemistry | Cell Line | Plant Extracts - chemistry | Plant Extracts - pharmacology | Humans | Thymus Plant - chemistry | Campylobacter jejuni - drug effects | Intestinal Mucosa - cytology | Animals | Swine | Epithelial Cells - microbiology | Polystyrenes | Bacterial Adhesion - drug effects | Olea - chemistry | Medicine, Herbal | Polystyrene | Analysis | Medicine, Botanic | Waste materials | Biofilms | Phytochemicals | Food science | Polystyrene resins | Byproducts | Bacteria | Olives | Wastes | Thyme | Adhesion | Campylobacter
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2. Full Text Lewy body extracts from Parkinson disease brains trigger α‐synuclein pathology and neurodegeneration in mice and monkeys
by Recasens, Ariadna and Dehay, Benjamin and Bové, Jordi and Carballo‐Carbajal, Iria and Dovero, Sandra and Pérez‐Villalba, Ana and Fernagut, Pierre‐Olivier and Blesa, Javier and Parent, Annabelle and Perier, Celine and Fariñas, Isabel and Obeso, José A and Bezard, Erwan and Vila, Miquel
Annals of Neurology, ISSN 0364-5134, 03/2014, Volume 75, Issue 3, pp. 351 - 362
Objective Mounting evidence suggests that α‐synuclein, a major protein component of Lewy bodies (LB), may be responsible for initiating and spreading the... 
TRANSMISSION | PROTEIN | DEMENTIA | INCLUSIONS | AGGREGATE | DISORDER | NEURONAL CELL-DEATH | BODIES | DYSFUNCTION | PREVENTS | NEUROSCIENCES | CLINICAL NEUROLOGY | Tissue Extracts - chemistry | Substantia Nigra - pathology | alpha-Synuclein - administration & dosage | Dopaminergic Neurons - pathology | Humans | Macaca mulatta | Nerve Degeneration - chemically induced | Nerve Degeneration - metabolism | Dopaminergic Neurons - metabolism | Dopaminergic Neurons - drug effects | Female | Parkinson Disease - metabolism | alpha-Synuclein - genetics | Lewy Bodies - metabolism | Corpus Striatum - pathology | Lewy Bodies - pathology | Lewy Bodies - chemistry | Parkinson Disease - pathology | Microinjections | alpha-Synuclein - toxicity | Nerve Degeneration - pathology | Mice, Knockout | alpha-Synuclein - isolation & purification | Substantia Nigra - drug effects | Animals | Corpus Striatum - drug effects | Mice | Tissue Extracts - toxicity | Parkinson Disease - etiology | Life Sciences
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3. Full Text Gel‐aided sample preparation (GASP)—A simplified method for gel‐assisted proteomic sample generation from protein extracts and intact cells
by Fischer, Roman and Kessler, Benedikt M
PROTEOMICS, ISSN 1615-9853, 04/2015, Volume 15, Issue 7, pp. 1224 - 1229
We describe a “gel‐assisted” proteomic sample preparation method for MS analysis. Solubilized protein extracts or intact cells are copolymerized with... 
Sample preparation | Comparative proteomics | Technology | Gel‐assisted sample preparation | Bottom‐up proteomics | Gel-assisted sample preparation | Bottom-up proteomics | DIGESTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | TISSUES | IDENTIFICATION | Humans | Cells, Cultured | Proteomics | Cell Extracts | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Proteome - chemistry | Acrylic Resins - chemistry | Proteome - isolation & purification | Proteins | Cysteine | Analysis | Denaturation | Methods
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4. Full Text Trifolium species-derived substances and extracts—Biological activity and prospects for medicinal applications
by Kolodziejczyk-Czepas, Joanna
Journal of Ethnopharmacology, ISSN 0378-8741, 08/2012, Volume 143, Issue 1, pp. 14 - 23
Despite of the fact that clovers (family: ; genus: ) have been known for many centuries as important forage plants and valuable herbs in folk medicine, their... 
Medicine | Phytoestrogens | Trifolium | Clover | RED-CLOVER ISOFLAVONES | CHEMISTRY, MEDICINAL | PLANT SCIENCES | SUPPLEMENTATION | PLASMA-LIPIDS | INTEGRATIVE & COMPLEMENTARY MEDICINE | AERIAL PARTS | PROSTATE-CANCER | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | GROWTH-FACTOR | POSTMENOPAUSAL WOMEN | PRATENSE ISOFLAVONES | Plant Extracts - chemistry | Anti-Inflammatory Agents - pharmacology | Plant Extracts - pharmacology | Humans | Polyphenols - pharmacology | Antioxidants - pharmacology | Trifolium - chemistry | Antioxidants - therapeutic use | Anti-Inflammatory Agents - therapeutic use | Saponins - therapeutic use | Phytotherapy | Polyphenols - therapeutic use | Plant Extracts - therapeutic use | Saponins - pharmacology | Legumes | Beans | Mimosaceae | Isoflavones
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5. Full Text The effects of chosen plant extracts and compounds on mesenchymal stem cells—a bridge between molecular nutrition and regenerative medicine‐ concise review
by Kornicka, Katarzyna and Kocherova, Ievgeniia and Marycz, Krzysztof
Phytotherapy Research, ISSN 0951-418X, 07/2017, Volume 31, Issue 7, pp. 947 - 958
Mesenchymal stem cells (MSC) stand as a promising tool in regenerative medicine because of their high therapeutic potential in treatment of degenerative,... 
plant derived compounds | osteogenesis | proliferation | mesenchymal stem cells | CHEMISTRY, MEDICINAL | INHIBITS ADIPOCYTE DIFFERENTIATION | OSTEOGENIC DIFFERENTIATION | IN-VITRO | HUMAN BONE-MARROW | SIGNALING PATHWAY | ENHANCES OSTEOGENESIS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | PROMOTES OSTEOBLAST DIFFERENTIATION | MARROW STROMAL CELLS | ADIPOGENIC DIFFERENTIATION | Mesenchymal Stromal Cells - drug effects | Cell Proliferation | Signal Transduction | Bone Marrow Cells - cytology | Plant Extracts - pharmacology | Humans | Adipose Tissue - cytology | Cell Differentiation | Regenerative Medicine | Osteogenesis | Phytoestrogens - pharmacology | Transplantation | Medicine, Herbal | Biological products | Cell differentiation | Medicine, Botanic | Stem cells | Adipose tissues | Cell proliferation | Surgical implants | Vegetables | Adipose tissue | Mesenchyme | Medical services | Seaweeds | Regeneration (physiology) | Fruits | Biomaterials | Signal transduction | Biomedical materials | Pathways | Bioactive compounds | Bone marrow | Biocompatibility | Herbs | Autografts | Nutrition | Tissue engineering | Algae | Plant extracts | Studies | Medicine | Bridges | Regeneration | Rope | Skin & tissue grafts | Transduction | Umbilical cord | Differentiation | In vitro methods and tests | Index Medicus
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6. Full Text Protection against septic shock and suppression of tumor necrosis factor alpha and nitric oxide production on macrophages and microglia by a standard aqueous extract of Mangifera indica L. (VIMANG ®) : Role of mangiferin isolated from the extract
by Garrido, Gabino and Delgado, René and Lemus, Yeny and Rodrı́guez, Janet and Garcı́a, Dagmar and Núñez-Sellés, Alberto J
Pharmacological Research, ISSN 1043-6618, 2004, Volume 50, Issue 2, pp. 165 - 172
The present study illustrates the effects of a standard aqueous extract, used in Cuba under the brand name of VIMANG , from the stem bark of Mangifera indica... 
Mangifera indica L | Endotoxic shock | Tumor necrosis factor | Nitric oxide | Mangiferin | endotoxic shock | nitric oxide | NATURAL-PRODUCTS | FACTOR-KAPPA-B | N-ACETYLCYSTEINE | FLAVONOIDS | mangiferin | SYNTHASE | tumor necrosis factor | INFLAMMATION | ENDOTHELIAL-CELLS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | MICE | INHIBITORS | Mangifera - chemistry | Tumor Necrosis Factor-alpha - metabolism | Water | Microglia - metabolism | Plant Extracts - chemistry | Shock, Septic - prevention & control | Shock, Septic - drug therapy | Phytotherapy | Disease Models, Animal | Xanthones - chemistry | Xanthones - therapeutic use | Cell Line | Drug Evaluation, Preclinical - methods | Xanthones - isolation & purification | Microglia - drug effects | Administration, Oral | Nitric Oxide - antagonists & inhibitors | Plant Extracts - isolation & purification | Macrophages - metabolism | Animals | Polysaccharides, Bacterial - adverse effects | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Nitric Oxide - metabolism | Plant Extracts - therapeutic use | Tumor Necrosis Factor-alpha - antagonists & inhibitors
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7. Full Text Preparation of joint extracts
by Liu, Shuang and Takemasa, Erika
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1868, pp. 41 - 45
Since mice are widely used to establish rheumatoid arthritis models, assessment of the pathogenesis of local arthritis is fundamental. Proteins are the most... 
Joint tissue | Protein extracts | Mouse | Cell isolation | Synovium
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8. Full Text The α-amylase and α-glucosidase inhibitory effects of Irish seaweed extracts
by Lordan, Sinéad and Smyth, Thomas J and Soler-Vila, Anna and Stanton, Catherine and Ross, R. Paul
Food Chemistry, ISSN 0308-8146, 12/2013, Volume 141, Issue 3, pp. 2170 - 2176
To date, numerous studies have reported on the antidiabetic properties of various plant extracts through inhibition of carbohydrate-hydrolysing enzymes. The... 
Seaweed | α-Amylase | Diabetes | α-Glucosidase | Antioxidant | Phenolics | BROWN-ALGAE | VIVO | PHENOLIC-COMPOUNDS | FOOD SCIENCE & TECHNOLOGY | alpha-Amylase | INGREDIENTS | ANTIOXIDANT CAPACITY | PHLOROTANNINS | IN-VITRO | NUTRITION & DIETETICS | ENZYMES | alpha-Glucosidase | CHEMISTRY, APPLIED | CYTOTOXICITY | Caco-2 Cells | alpha-Amylases - antagonists & inhibitors | Glycoside Hydrolase Inhibitors | Plant Extracts - chemistry | Humans | Phaeophyta - chemistry | Vegetables - chemistry | alpha-Amylases - chemistry | Enzyme Inhibitors - chemistry | Ireland | Kinetics | Seaweed - chemistry | Ascophyllum - chemistry | alpha-Glucosidases - chemistry
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9. Full Text Fucoidan extracts ameliorate acute colitis
by Lean, Qi Ying and Eri, Rajaraman D and Fitton, J. Helen and Patel, Rahul P and Gueven, Nuri
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0128453
Inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, are an important cause of morbidity and impact significantly on quality of... 
INTESTINAL INFLAMMATION | MOLECULAR-WEIGHT FUCOIDAN | IN-VITRO | SULFATED POLYSACCHARIDE | INFLAMMATORY-BOWEL-DISEASE | CROHNS-DISEASE | BROWN SEAWEEDS | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | GUT INFLAMMATION | SODIUM-INDUCED COLITIS | Plant Extracts - chemistry | Plant Extracts - pharmacology | Body Weight - drug effects | Colitis - pathology | Fucus - chemistry | Male | Neutrophil Infiltration - physiology | Colitis - chemically induced | Polysaccharides - chemistry | Colitis - drug therapy | Spleen - pathology | Disease Models, Animal | Neutrophil Infiltration - immunology | Polysaccharides - therapeutic use | Acute Disease | Cytokines - metabolism | Administration, Oral | Colon - pathology | Mice, Inbred C57BL | Colon - metabolism | Polysaccharides - pharmacology | Dextran Sulfate - toxicity | Animals | Polyphenols - chemistry | Fucus - metabolism | Mice | Plant Extracts - therapeutic use | Dextran | Health aspects | Analysis | Ulcerative colitis | Inflammatory bowel diseases | Body weight | Medical services | Polysaccharides | Intestine | Remission | Colon | Saccharides | Immune system | Spleen | Edema | Goblet cells | Cytokines | Algae | Oral administration | Diarrhea | Histology | Fucoidan | Morbidity | Quality of life | Pathology | Sodium | Weight reduction | Infiltration | Fucose
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10. Full Text Antioxidant and anticancer activities of Chenopodium quinoa leaves extracts – In vitro study
by Gawlik-Dziki, Urszula and Świeca, Michał and Sułkowski, Maciej and Dziki, Dariusz and Baraniak, Barbara and Czyż, Jarosław
Food and Chemical Toxicology, ISSN 0278-6915, 07/2013, Volume 57, pp. 154 - 160
The nutraceutical potential of Leaves (ChL) was assessed through analyses of their phenolic content, elucidation of the effect of ChL phenolic compounds on... 
Bioaccessibility in vitro | Phenolics | Antioxidant activity | Anticancer activity | Chenopodium quinoa | MIGRATION | VITAMIN-E | PHENOLIC-COMPOUNDS | FOOD SCIENCE & TECHNOLOGY | INTENSITY | CELL-POPULATIONS | CANCER | POLYPHENOLS | PROSTATE CARCINOMA | TOXICOLOGY | BROCCOLI SPROUTS | PROGRESSION | Plant Leaves - chemistry | Plant Extracts - chemistry | Reactive Oxygen Species - metabolism | Antioxidants - chemistry | Plant Extracts - pharmacology | Rats | Antineoplastic Agents, Phytogenic - chemistry | Biological Availability | Male | Antioxidants - pharmacology | Chenopodium quinoa - chemistry | Plant Extracts - analysis | Phenols - analysis | Animals | Phenols - pharmacokinetics | Cell Line, Tumor | Phenols - chemistry | Oxidative Stress - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Dietary Supplements | Drug Screening Assays, Antitumor | Phenols - pharmacology | Antioxidants | Quinoa | Care and treatment | Cancer | Index Medicus
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11. Full Text In‐vitro cytotoxicity of various Siphonochilus aethiopicus (Schweinf.) B.L. Burtt extracts in combination with selected tableting excipients
by Erasmus, Mandi and Plessis, Lissinda H and Viljoen, Joe M
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 11/2019, Volume 71, Issue 11, pp. 1714 - 1724
Objectives To investigate the cytotoxic potential of S. aethiopicus extracts in combination with chitosan and Pharmacel®101, on two cell lines. Methods... 
apoptosis | Siphonochilus aethiopicus | cytotoxicity | tablet excipients | crude extracts | Cell death | Biological products | Biotechnology | Excipients | Membranes | Ethanol | Diethyl ether | Toxicity | Cytotoxicity | Exposure | Organic chemistry | Diet | Cell lines | Biomarkers | Bioindicators | Chitosan | Viability | Apoptosis | Integrity
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