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Journal Article
Journal Article
Cell stem cell, ISSN 1934-5909, 2014, Volume 14, Issue 2, pp. 237 - 252
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 550, Issue 7674, pp. 128 - 132
...(1) and is associated with multiple diseases. Histone deacetylase inhibitors are currently approved to treat certain cancers, but progress on the development of drug-like histone actyltransferase inhibitors has lagged behind(2... 
ANDROGEN RECEPTOR | ACETYLTRANSFERASES P300 | MULTIDISCIPLINARY SCIENCES | SMALL-MOLECULE INHIBITOR | HISTONE | Catalytic Domain - drug effects | p300-CBP Transcription Factors - antagonists & inhibitors | Prostatic Neoplasms, Castration-Resistant - enzymology | Histone Acetyltransferases - chemistry | Humans | Receptors, Androgen - metabolism | Crystallography, X-Ray | Male | Antineoplastic Agents - therapeutic use | Hematologic Neoplasms - enzymology | Hematologic Neoplasms - pathology | Cell Lineage - drug effects | Heterocyclic Compounds, 4 or More Rings - pharmacology | Prostatic Neoplasms, Castration-Resistant - pathology | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Biocatalysis - drug effects | Histone Acetyltransferases - metabolism | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | p300-CBP Transcription Factors - chemistry | Binding, Competitive | Enzyme Inhibitors - pharmacology | Heterocyclic Compounds, 4 or More Rings - chemistry | Models, Molecular | Neoplasms - enzymology | Prostatic Neoplasms, Castration-Resistant - drug therapy | Antineoplastic Agents - chemistry | Mice, SCID | Enzyme Inhibitors - therapeutic use | Acetyl Coenzyme A - metabolism | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | p300-CBP Transcription Factors - metabolism | Animals | Histone Acetyltransferases - antagonists & inhibitors | Cell Line, Tumor | Hematologic Neoplasms - drug therapy | Protein Conformation | Cell Proliferation - drug effects | Mice | Neoplasms - pathology | Care and treatment | Chemical inhibitors | Usage | Transferases | Binding proteins | Health aspects | Tumors | Histone deacetylase | Transcription factors | Molecular structure | Transcription | Peptides | Androgen receptors | Amino acids | Event-related potentials | Selectivity | Catalytic activity | Kinases | Experiments | Crystallography | Proteins | CREB-binding protein | Castration | Xenografts | Coenzyme A | Acetylation | Catalysis | Inhibition | Crystal structure | Hematology | Feasibility studies | Cyclic AMP response element-binding protein | Histone acetyltransferase | Inhibitors | Microscopy | Natural products | Regulatory mechanisms (biology) | Epigenetics | Ligands | Prostate cancer | Prostate | Cancer | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Journal Article
Nature neuroscience, ISSN 1546-1726, 2010, Volume 13, Issue 5, pp. 541 - 550
The mechanisms that regulate the developmental potential of adult neural progenitor populations under physiological and pathological conditions remain poorly... 
PROGENITOR CELLS | NEURAL STEM-CELLS | MULTIPLE-SCLEROSIS | BONE MORPHOGENETIC PROTEIN | OLIG GENE-FUNCTION | MOUSE | SPINAL-CORD | CENTRAL-NERVOUS-SYSTEM | SUBVENTRICULAR ZONE | NEUROSCIENCES | BRAIN | Microtubule-Associated Proteins - genetics | Neuronal Plasticity - drug effects | Green Fluorescent Proteins - genetics | Glycoproteins - pharmacology | Cell Lineage - drug effects | Neurogenesis - genetics | Cell Differentiation - genetics | Oligodendroglia - drug effects | Oligodendroglia - physiology | Neurons - physiology | Demyelinating Diseases - chemically induced | Neurogenesis - drug effects | Bromodeoxyuridine - metabolism | Neuropeptides - genetics | Demyelinating Diseases - pathology | Neurons - drug effects | Cell Lineage - genetics | Adult Stem Cells - drug effects | Cerebral Ventricles - pathology | Lysophosphatidylcholines | Myelin Basic Protein - metabolism | Glutamate Decarboxylase - genetics | Mice, Transgenic | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Cell Movement - drug effects | Corpus Callosum - cytology | Animals | Cell Count - methods | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Mice | Physiological aspects | Genetic aspects | Research | Demyelinating diseases | Gene expression | Adaptation (Physiology)
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 4/2013, Volume 110, Issue 18, pp. 7294 - 7299
Despite recent insights gained from the effects of targeted deletion of the Finkel-Biskis-Jinkins osteosarcoma oncogene (c-fos... 
Transcription factors | Osteopetrosis | Genes | Cell lines | Bones | Osteoclasts | Giant cells | Gene expression regulation | Macrophages | Binding sites | Cell lineage commitment | Osteoclast differentiation | Bone homeostasis | Osteopetrosis phenotype | cell lineage commitment | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | osteoclast differentiation | INDUCTION | GRANULOCYTE | BONE-RESORPTION | gene expression regulation | B-CELLS | bone homeostasis | MICE | osteopetrosis phenotype | DIFFERENTIATION | OSTEOPETROSIS | Osteopetrosis - diagnostic imaging | CCAAT-Enhancer-Binding Protein-alpha - metabolism | Femur - pathology | Osteopetrosis - physiopathology | Monocytes - cytology | Molecular Sequence Data | CCAAT-Enhancer-Binding Protein-alpha - deficiency | Femur - diagnostic imaging | Cell Lineage - drug effects | Promoter Regions, Genetic - genetics | Tibia - pathology | Cell Differentiation - genetics | RANK Ligand - pharmacology | Base Sequence | Cell Lineage - genetics | Osteogenesis - genetics | Tibia - physiopathology | Animals, Newborn | Biomarkers - metabolism | Cell Line | Osteoclasts - pathology | Osteopetrosis - pathology | Osteogenesis - drug effects | Proto-Oncogene Proteins c-fos - metabolism | Tibia - diagnostic imaging | Femur - drug effects | DNA - metabolism | Macrophages - cytology | Femur - physiopathology | Tibia - drug effects | Osteoclasts - metabolism | Regulatory Sequences, Nucleic Acid - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Radiography | Macrophages - metabolism | Organ Size - drug effects | Phenotype | Animals | Cathepsin K - metabolism | Cell Differentiation - drug effects | Macrophages - drug effects | Mice | Osteoclasts - enzymology | Osteoclasts - drug effects | Biological Sciences
Journal Article
Cancer cell, ISSN 1535-6108, 2011, Volume 20, Issue 1, pp. 53 - 65
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 31, pp. 9638 - 9643
Journal Article