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Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 153 - 158
Inflammatory caspases (caspases 1, 4, 5 and 11) are activated in response to microbial infection and danger signals. When activated, they cleave mouse and... 
LISTERIA-MONOCYTOGENES | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | MIXED LINEAGE KINASE | PERFORIN | NLRP3 INFLAMMASOME | INTRACELLULAR BACTERIA | GRANZYMES | CASPASE-1 ACTIVATION | GRANULYSIN | CELL-DEATH | Conserved Sequence - genetics | Inflammasomes - metabolism | Phosphatidylinositol Phosphates - metabolism | Pyroptosis - drug effects | Escherichia coli - drug effects | Humans | Molecular Sequence Data | Neoplasm Proteins - pharmacology | Escherichia coli - cytology | Neoplasm Proteins - metabolism | Escherichia coli - metabolism | Protein Multimerization - genetics | Listeria monocytogenes - metabolism | Cell Membrane - metabolism | Membrane Proteins - metabolism | Listeria monocytogenes - cytology | Porosity - drug effects | Neoplasm Proteins - genetics | Cell Membrane - drug effects | Staphylococcus aureus - metabolism | Amino Acid Sequence | Cell Line | Microbial Viability - drug effects | Membrane Proteins - genetics | Mice, Inbred C57BL | Phosphatidylserines - metabolism | Neoplasm Proteins - chemistry | Cardiolipins - metabolism | Cell Membrane - ultrastructure | Protein Structure, Tertiary - genetics | Microscopy, Electron | Pyroptosis - genetics | Protein Transport | Liposomes - chemistry | Animals | Membrane Proteins - chemistry | Cell Membrane Permeability - drug effects | Staphylococcus aureus - cytology | Liposomes - metabolism | Mice | Mutation | Staphylococcus aureus - drug effects | Listeria monocytogenes - drug effects | Observations | Apoptosis | Proteins | Membranes | Bacterial infections | Immunology | Plasmids | Bacteria | Infections | Cells | Index Medicus
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2017, Volume 60, Issue 5, pp. 1665 - 1672
Macrocyclic peptides are considered large enough to inhibit "undruggable" targets, but the design of passively cell-permeable molecules in this space remains a... 
Adsorption | Cell Membrane Permeability - drug effects | Humans | Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 5, pp. 911 - 921
Background & Aims We evaluated the gastrointestinal permeability and bacterial translocation in cirrhotic patients with portal hypertension (PHT) prior to and... 
Gastroenterology and Hepatology | Antigliadin antibodies | HVPG | Intestinal permeability | Gastroduodenal permeability | Hepatic venous pressure gradient | NOD2 | Bacterial translocation | TLR2 | SURVIVAL | TRANSLOCATION | PROPRANOLOL | ASCITES | SPONTANEOUS BACTERIAL PERITONITIS | GASTRIC PERMEABILITY | HYPERDYNAMIC CIRCULATION | INFECTION | PORTAL-HYPERTENSIVE GASTROPATHY | GASTROENTEROLOGY & HEPATOLOGY | CHRONIC LIVER-DISEASES | Follow-Up Studies | Lactulose - metabolism | Humans | Middle Aged | Intestinal Absorption - drug effects | Male | Bacterial Translocation - drug effects | Hemodynamics - physiology | Liver Cirrhosis - epidemiology | Adrenergic beta-Antagonists - pharmacology | Interleukin-6 - blood | Mannitol - metabolism | Liver Cirrhosis - metabolism | Sucrose - metabolism | Adult | Female | Adrenergic beta-Antagonists - therapeutic use | Intestinal Absorption - physiology | Carrier Proteins - blood | Liver Cirrhosis - drug therapy | Bacterial Translocation - physiology | Acute-Phase Proteins | Comorbidity | Kaplan-Meier Estimate | Membrane Glycoproteins - blood | Hypertension, Portal - drug therapy | Hypertension, Portal - epidemiology | Cell Membrane Permeability - physiology | Hypertension, Portal - metabolism | Cell Membrane Permeability - drug effects | Aged | Hemodynamics - drug effects | Hypertension | Care and treatment | Permeability | Liver cirrhosis | Venous pressure | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 111 - 116
Journal Article