X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (223732) 223732
Book Chapter (1587) 1587
Newspaper Article (783) 783
Newsletter (584) 584
Magazine Article (227) 227
Book / eBook (116) 116
Dissertation (58) 58
Conference Proceeding (49) 49
Reference (49) 49
Transcript (43) 43
Publication (17) 17
Trade Publication Article (13) 13
Government Document (11) 11
Book Review (7) 7
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (118902) 118902
humans (108963) 108963
cell biology (50414) 50414
mice (47290) 47290
male (43951) 43951
apoptosis (40491) 40491
proteins (38393) 38393
rats (36599) 36599
female (34570) 34570
biochemistry & molecular biology (34287) 34287
cancer (32131) 32131
expression (30789) 30789
gene expression (28568) 28568
neurosciences (28421) 28421
oncology (27677) 27677
research (25364) 25364
signal transduction (24420) 24420
cell line, tumor (23563) 23563
cells, cultured (23481) 23481
cells (22221) 22221
activation (21307) 21307
analysis (20546) 20546
kinases (19285) 19285
multidisciplinary sciences (18951) 18951
research article (18828) 18828
phosphorylation (18719) 18719
cell line (18360) 18360
cell nucleus - metabolism (17564) 17564
medicine (17242) 17242
physiological aspects (17054) 17054
oxidative stress (16594) 16594
apoptosis - drug effects (16065) 16065
health aspects (15869) 15869
biology (15842) 15842
rodents (15262) 15262
inflammation (15133) 15133
gene-expression (14709) 14709
in-vitro (14296) 14296
pharmacology & pharmacy (14157) 14157
genetic aspects (14086) 14086
cell cycle (13767) 13767
stem cells (13445) 13445
tumors (13443) 13443
science (13095) 13095
signal transduction - drug effects (12810) 12810
physiology (12640) 12640
neurons (12431) 12431
rats, sprague-dawley (12408) 12408
cell proliferation (12217) 12217
inhibition (12034) 12034
life sciences (12014) 12014
medicine, research & experimental (11840) 11840
immunology (11668) 11668
immunohistochemistry (11389) 11389
biomedicine (11229) 11229
genes (11190) 11190
brain (10994) 10994
dose-response relationship, drug (10756) 10756
care and treatment (10734) 10734
cell nucleus - drug effects (10710) 10710
mutation (10619) 10619
cell proliferation - drug effects (10363) 10363
cell survival - drug effects (10269) 10269
in-vivo (10263) 10263
protein (10182) 10182
time factors (9909) 9909
nf-kappa-b (9868) 9868
review (9591) 9591
growth (9537) 9537
deoxyribonucleic acid--dna (9519) 9519
mice, inbred c57bl (9467) 9467
disease models, animal (9380) 9380
studies (9278) 9278
differentiation (9263) 9263
biochemistry (9183) 9183
transcription (9076) 9076
neurology (9031) 9031
metastasis (8928) 8928
transcription factors (8782) 8782
cytokines (8727) 8727
biochemistry, general (8647) 8647
proliferation (8587) 8587
cell death (8548) 8548
chemotherapy (8524) 8524
metabolism (8515) 8515
enzymes (8458) 8458
blotting, western (8451) 8451
cell growth (8329) 8329
dna (8321) 8321
transfection (8180) 8180
adult (8111) 8111
development and progression (8015) 8015
rna, messenger - metabolism (7864) 7864
middle aged (7842) 7842
genetics & heredity (7838) 7838
rats, wistar (7811) 7811
endocrinology & metabolism (7804) 7804
antineoplastic agents - pharmacology (7753) 7753
breast cancer (7733) 7733
mitochondria (7697) 7697
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (47) 47
UofT at Mississauga - Stacks (13) 13
Collection Dvlpm't (Acquisitions) - Vendor file (11) 11
UofT at Scarborough - Stacks (7) 7
St. Michael's College (John M. Kelly) - Circulation Desk (4) 4
Collection Dvlpm't (Acquisitions) - Closed Orders (3) 3
Credit Valley Hospital - Reserve desk (3) 3
Gerstein Science - Circulation Desk (3) 3
St. Michael's College (John M. Kelly) - 2nd Floor (3) 3
St. Michael's Hospital - Stacks (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (3) 3
Victoria University E.J. Pratt - Oversize (3) 3
Earth Sciences (Noranda) - Stacks (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Reference (2) 2
UTL at Downsview - May be requested (2) 2
Dentistry (Harry R Abbott) - Circulation Desk (1) 1
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (1) 1
Dentistry (Harry R Abbott) - Stacks (1) 1
Dentistry (Harry R Abbott) - Withdrawn (1) 1
Earth Sciences (Noranda) - Circulation Desk (1) 1
Earth Sciences (Noranda) - Oversize (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Gerstein Science - Not Returned (1) 1
Gerstein Science - Periodical Stacks (1) 1
Gerstein Science - Reserve desk (1) 1
Gerstein Science - Searching (1) 1
Media Commons - Microtexts (1) 1
Online Resources - Online (1) 1
Physics - Course Reserves (1) 1
St. Michael's College (John M. Kelly) - Missing (1) 1
St. Michael's Hospital - Circulation Desk (1) 1
Sunnybrook Health Sciences Centre - Holland Reference (1) 1
Trillium Health Centre - Reserve desk (1) 1
Trillium Health Centre - Stacks (1) 1
Trinity College (John W Graham) - Stacks (1) 1
UofT at Mississauga - Circulation Desk (1) 1
Victoria University E.J. Pratt - Circulation Desk (1) 1
West Park Healthcare Centre - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (225714) 225714
Russian (742) 742
Japanese (690) 690
German (416) 416
Chinese (378) 378
French (209) 209
Polish (56) 56
Italian (40) 40
Spanish (34) 34
Ukrainian (34) 34
Czech (9) 9
Portuguese (8) 8
Bulgarian (5) 5
Slovak (5) 5
Dutch (4) 4
Korean (4) 4
Romanian (4) 4
Hungarian (2) 2
Slovenian (2) 2
Turkish (2) 2
Danish (1) 1
Irish (1) 1
Persian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Plant physiology (Bethesda), ISSN 1532-2548, 2017, Volume 175, Issue 3, pp. 1321 - 1336
Long noncoding RNAs (lncRNAs) affect gene expression through a wide range of mechanisms and are considered as important regulators in many essential biological... 
SIGNALING AND RESPONSE | ARABIDOPSIS-THALIANA | ABIOTIC STRESS | SEED-GERMINATION | MESSENGER-RNA | PHOSPHATE HOMEOSTASIS | ANTISENSE RNA | ABSCISIC-ACID BIOSYNTHESIS | GENE FAMILY | GENOME-WIDE IDENTIFICATION | TRANSCRIPTION FACTOR | PLANT SCIENCES | Arabidopsis - physiology | Reactive Oxygen Species - metabolism | Genes, Plant | Proline - metabolism | Sodium Chloride - pharmacology | Seedlings - genetics | RNA, Messenger - metabolism | Salt-Tolerance - drug effects | Arabidopsis Proteins - metabolism | Cell Nucleus - metabolism | Droughts | Plants, Genetically Modified | Salt-Tolerance - genetics | Plant Leaves - drug effects | Stress, Physiological - drug effects | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Subcellular Fractions - drug effects | Stress, Physiological - genetics | RNA, Messenger - genetics | Up-Regulation - genetics | RNA, Long Noncoding - genetics | Seedlings - drug effects | Down-Regulation - drug effects | Mutation - genetics | Subcellular Fractions - metabolism | Down-Regulation - genetics | Arabidopsis - genetics | Up-Regulation - drug effects | Abscisic Acid - pharmacology | Gene Expression Regulation, Plant - drug effects | Plant Leaves - genetics | Cell Nucleus - drug effects | RNA, Long Noncoding - metabolism | Plant Leaves - physiology | Arabidopsis thaliana | RNA sequencing | Plant-soil relationships | Soils, Salts in | Genetic aspects | Health aspects | Methods | Signaling and Response
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2012, Volume 109, Issue 47, pp. 19486 - 19491
... at the endoplasmic reticulum (ER) membrane to transcription factors in the nucleus is unknown. To close this gap in our understanding of the ethylene signaling pathway, the challenge has been to identify the target of the CONSTITUTIVE TRIPLE RESPONSE1 (CTR1... 
Proteins | Phosphorylation | Phenotypes | Receptors | Transcription factors | Onions | Epidermal cells | Mass spectroscopy | Regulator genes | Seedlings | Mass spectrometry | Serine | serine | MASS-SPECTROMETER | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | RECEPTOR | ETR1 | RAF-LIKE KINASE | RESPONSE PATHWAY | THALIANA | COLOCALIZATION | mass spectrometry | PLANTS | ENDOPLASMIC-RETICULUM | Protein Kinases - metabolism | Endoplasmic Reticulum - metabolism | Molecular Sequence Data | Protein Kinases - chemistry | Protein Transport - drug effects | Ethylenes - metabolism | Arabidopsis Proteins - metabolism | Cell Nucleus - metabolism | Endoplasmic Reticulum - drug effects | Receptors, Cell Surface - chemistry | Phosphorylation - drug effects | Ethylenes - pharmacology | Amino Acid Sequence | Arabidopsis - drug effects | Receptors, Cell Surface - metabolism | Phosphoserine - metabolism | Arabidopsis - metabolism | Arabidopsis Proteins - chemistry | Signal Transduction - drug effects | Models, Biological | Amino Acid Substitution - genetics | Intracellular Membranes - drug effects | Cell Nucleus - drug effects | Plant Growth Regulators - metabolism | Plant Growth Regulators - pharmacology | Intracellular Membranes - metabolism | Arabidopsis | Plant genetics | Physiological aspects | Genetic aspects | Research | Health aspects | Membrane proteins | Biological Sciences
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2016, Volume 36, Issue 32, pp. 8441 - 8452
.... In the present study, we show that chronic social defeat stress, an ethologically validated model of depression in mice, increases SIRT1 levels in the nucleus accumbens (NAc... 
Striatum | Cell-type specific | Depression | Anxiety | Epigenetic | Stress | stress | CHROMATIN REGULATION | epigenetic | NAD(+)-DEPENDENT DEACETYLATION | CIRCADIAN CONTROL | NEUROSCIENCES | EMOTIONAL STIMULI | anxiety | striatum | PATHWAY | SOCIAL DEFEAT | GENE-EXPRESSION | depression | cell-type specific | CRE-RECOMBINASE | CALORIE RESTRICTION | Sirtuin 1 - metabolism | Food Preferences - physiology | Male | Nucleus Accumbens - physiology | Sirtuin 1 - genetics | Drug Delivery Systems | Depression - etiology | Depression - drug therapy | Exploratory Behavior - physiology | Depression - metabolism | Swimming - psychology | Dopaminergic Neurons - metabolism | Nucleus Accumbens - cytology | Stress, Psychological - metabolism | Exploratory Behavior - drug effects | Dopaminergic Neurons - drug effects | Antidepressive Agents - pharmacology | Disease Models, Animal | Maze Learning - physiology | Food Preferences - drug effects | Mice, Inbred C57BL | Gene Expression Regulation - physiology | Mice, Transgenic | Maze Learning - drug effects | Sirtuin 1 - antagonists & inhibitors | Antidepressive Agents - therapeutic use | Gene Expression Regulation - drug effects | Receptors, Dopamine D1 | Animals | Receptors, Dopamine D2 | Carbazoles - therapeutic use | Mice | Carbazoles - pharmacology | Nucleus Accumbens - drug effects | Stress, Psychological - complications
Journal Article
Cell death & disease, ISSN 2041-4889, 2016, Volume 7, Issue 10, pp. e2441 - e2441
Journal Article
Plant physiology (Bethesda), ISSN 0032-0889, 10/2013, Volume 163, Issue 2, pp. 867 - 881
The plastid genome is highly conserved among plant species, suggesting that alterations of its structure would have dramatic impacts on plant fitness.... 
Oxidative stress | Leaves | Reactive oxygen species | Phenotypes | Chloroplasts | Genes | Genomes | SIGNALING AND RESPONSE | Plants | Plastids | Chlorophylls | VARIEGATION MUTANTS | RESPONSES | OXIDATIVE STRESS | GENE | CHLOROPLAST DEVELOPMENT | PHOTOSYSTEM-II | SINGLET OXYGEN | LIGHT STRESS | TOPOISOMERASE-IV | DNA-POLYMERASES | PLANT SCIENCES | Cell Death - radiation effects | Genome, Plastid - genetics | Inheritance Patterns - drug effects | Reactive Oxygen Species - metabolism | Cellular Reprogramming - radiation effects | Arabidopsis - growth & development | Adaptation, Physiological - drug effects | Stress, Physiological - radiation effects | Arabidopsis Proteins - metabolism | Arabidopsis - radiation effects | Cell Nucleus - metabolism | Photosynthesis - genetics | Adaptation, Physiological - genetics | Cell Nucleus - radiation effects | Light | Plastids - drug effects | Genomic Instability - drug effects | Inheritance Patterns - genetics | Plastids - genetics | Stress, Physiological - drug effects | Cell Death - drug effects | Signal Transduction - radiation effects | Cellular Reprogramming - genetics | DNA, Plant - genetics | Inheritance Patterns - radiation effects | Photosynthesis - radiation effects | Genomic Instability - radiation effects | Arabidopsis Proteins - genetics | Stress, Physiological - genetics | Arabidopsis - ultrastructure | Ciprofloxacin - pharmacology | Signal Transduction - genetics | Adaptation, Physiological - radiation effects | Mutation - genetics | Arabidopsis - genetics | Cellular Reprogramming - drug effects | Phenotype | Signal Transduction - drug effects | Photosynthesis - drug effects | Plastids - ultrastructure | Gene Rearrangement - genetics | Plastids - radiation effects | Cell Nucleus - drug effects | Arabidopsis thaliana | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Gene expression
Journal Article
Psychopharmacology (Berlin, Germany), ISSN 1432-2072, 2018, Volume 236, Issue 1, pp. 531 - 543
Environmental stimuli, or cues, associated with the use of drugs such as cocaine are one of the primary drivers of relapse... 
Reconsolidation | Self-administration | Neurosciences | Phosphorylation | Biomedicine | Extinction | Memory | Proteomics | Cocaine | Pharmacology/Toxicology | Psychiatry | DRUG | CORE | PSYCHIATRY | BASOLATERAL AMYGDALA | DISRUPTING RECONSOLIDATION | KINASE | D-CYCLOSERINE | MECHANISMS | CONTEXT | NEUROSCIENCES | SEEKING | PHARMACOLOGY & PHARMACY | CUE-EXPOSURE | Amygdala - physiopathology | Recurrence | Amygdala - drug effects | Extinction, Psychological - drug effects | Male | Cocaine-Related Disorders - physiopathology | Motivation - drug effects | Self Administration | Basolateral Nuclear Complex - physiopathology | Phosphoproteins | Extinction, Psychological - physiology | Basolateral Nuclear Complex - drug effects | Cues | Nucleus Accumbens - physiopathology | Receptors, GABA-B - drug effects | Rats | Receptors, GABA-B - physiology | Mental Recall - drug effects | Rats, Sprague-Dawley | Association Learning - physiology | Association Learning - drug effects | Animals | Motivation - physiology | Signal Transduction - drug effects | Mental Recall - physiology | Signal Transduction - physiology | Nucleus Accumbens - drug effects | Psychological aspects | Extinction (Psychology) | Nucleus accumbens | Cell interaction | Physiological aspects | Research | Neurological research | γ-Aminobutyric acid B receptors | Drug abuse | Amygdala | Serine | Mass spectroscopy | Pharmacology | Kinases | Environmental effects | Proteins | Drug self-administration | Syntaxin | Signaling | Sensory integration | Cascades | Rodents | Syntaxin 1 | Nuclei (cytology) | Mass spectrometry | memory | extinction | proteomics | cocaine | self-administration | reconsolidation | phosphorylation
Journal Article
Nature Neuroscience, ISSN 1097-6256, 07/2013, Volume 16, Issue 7, pp. 874 - 883
.... Arc expression is robustly induced by activity, and Arc protein localizes to both active synapses and the nucleus... 
CONSOLIDATION | EARLY GENE ARC/ARG3.1 | CYTOSKELETON-ASSOCIATED PROTEIN | MESSENGER-RNA | ACTIN POLYMERIZATION | LONG-TERM POTENTIATION | DENTATE GYRUS | TRANSLATION | SYNAPTIC PLASTICITY | EXPRESSION | NEUROSCIENCES | Disks Large Homolog 4 Protein | Cytoskeletal Proteins - genetics | Embryo, Mammalian | Nuclear Localization Signals - genetics | Rats, Long-Evans | Neuronal Plasticity - drug effects | Male | Protein Transport - drug effects | Excitatory Postsynaptic Potentials - drug effects | Cell Nucleus - metabolism | Neuronal Plasticity - physiology | Neurons - ultrastructure | beta-Galactosidase - metabolism | Cytoskeletal Proteins - metabolism | Membrane Proteins - metabolism | Homeostasis - drug effects | Tetrodotoxin - pharmacology | Neurons - drug effects | Excitatory Postsynaptic Potentials - genetics | Receptors, AMPA - metabolism | GABA-A Receptor Antagonists - pharmacology | Brain - cytology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Proto-Oncogene Proteins c-fos - metabolism | Nuclear Localization Signals - metabolism | Rats | Mice, Transgenic | Bicuculline - pharmacology | Mutation - genetics | Nerve Tissue Proteins - genetics | Protein Transport - genetics | Nerve Tissue Proteins - metabolism | Animals | Homeostasis - physiology | Guanylate Kinases - metabolism | Mice | beta-Galactosidase - genetics | Cell Nucleus - drug effects | Homeostasis - genetics | Cellular control mechanisms | Tumor suppressor genes | Neural transmission | Genetic aspects | Research | Properties | Gene expression
Journal Article
Journal Article
The Journal of neuroscience, ISSN 1529-2401, 2002, Volume 22, Issue 1, pp. 350 - 356
The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus has been referred to as the master circadian pacemaker that drives daily rhythms in behavior and physiology... 
Suprachiasmatic nucleus | Jet lag | Pineal | Arcuate nucleus | Luciferase | Pituitary | Entrainment | Olfactory bulb | Per | pituitary | pineal | olfactory bulb | MPER1 | entrainment | LIGHT | RAT SUPRACHIASMATIC NUCLEUS | DROSOPHILA PERIOD GENE | jet lag | MULTIUNIT | NEUROSCIENCES | arcuate nucleus | luciferase | NEURONS | PACEMAKER | suprachiasmatic nucleus | EXPRESSION | CLOCK | Paraventricular Hypothalamic Nucleus - physiology | Suprachiasmatic Nucleus - drug effects | Transgenes - physiology | Gene Expression - drug effects | Male | Brain - physiology | Biological Clocks - drug effects | Luciferases - genetics | Suprachiasmatic Nucleus - physiology | Arcuate Nucleus of Hypothalamus - drug effects | Gene Expression - physiology | Female | Animals, Genetically Modified | Colforsin - pharmacology | Cells, Cultured | Periodicity | Pineal Gland - physiology | Rats | Circadian Rhythm - physiology | Photoperiod | Pineal Gland - drug effects | Arcuate Nucleus of Hypothalamus - physiology | Organ Specificity | Period Circadian Proteins | Genes, Reporter - physiology | Brain - drug effects | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Biological Clocks - physiology | Nuclear Proteins - physiology | In Vitro Techniques | Circadian Rhythm - drug effects | Cell Cycle Proteins | Pituitary Gland - drug effects | Pituitary Gland - physiology
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 09/2016, Volume 42, pp. 90 - 101
[Display omitted] Clinical application of cell-penetrating peptides (CPPs) in cancer therapy is greatly restricted due to lack of tissue selectivity and... 
Combined administration | Synergistic effect | Glioma | Cell-penetrating peptide | NF-κB peptide inhibitor | MATERIALS SCIENCE, BIOMATERIALS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | SIRNA DELIVERY | TAT PEPTIDE | NANOPARTICLES | IN-VITRO | INTERNALIZATION | TARGETING DELIVERY | INTRACELLULAR DELIVERY | NF-kappa B peptide inhibitor | NF-KAPPA-B | LIPOSOMES | Doxorubicin - therapeutic use | Capillaries - pathology | Apoptosis - drug effects | Humans | Brain Neoplasms - pathology | Spheroids, Cellular - pathology | Body Weight - drug effects | Male | Brain - blood supply | Cell-Penetrating Peptides - pharmacology | Cell-Penetrating Peptides - therapeutic use | Cell Nucleus - metabolism | Glioma - pathology | Spheroids, Cellular - drug effects | Cell-Penetrating Peptides - chemistry | Doxorubicin - administration & dosage | Amino Acid Sequence | Tissue Distribution - drug effects | Endothelial Cells - metabolism | Brain Neoplasms - drug therapy | Drug Synergism | Animals | Tumor Burden - drug effects | Mice, Nude | Cell Membrane Permeability - drug effects | Brain - pathology | Cell Line, Tumor | Cell Nucleus - drug effects | Doxorubicin - pharmacology | Glioma - drug therapy | Endothelial Cells - drug effects | Anthracyclines | Peptides | Drug therapy | Gliomas | Drugs | Chemotherapy | Drug delivery systems | Biological products | Brain tumors | Vehicles | Cancer | Therapy | Brain | Position (location) | Nuclei | Doxorubicin | Tumors
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2017, Volume 96, Issue 1, pp. 130 - 144.e6
Individuals suffering from substance-use disorders develop strong associations between the drug’s rewarding effects and environmental cues, creating powerful, enduring triggers for relapse... 
NPAS4 | HDAC5 | cocaine addiction | reinstatement | conditioned place preference | ChIP-seq | nucleus accumbens | histone deacetylase | drug self-administration | chromatin immunoprecipitation | WEBGESTALT | DELTA-FOSB | PLACE PREFERENCE | REINSTATEMENT | ENSEMBLES | INCREASES | RECEPTOR | TRANSCRIPTION FACTOR | BINDING | EXPRESSION | NEUROSCIENCES | Basic Helix-Loop-Helix Transcription Factors - physiology | Conditioning (Psychology) - physiology | Drug-Seeking Behavior - physiology | Reinforcement (Psychology) | Conditioning, Operant - physiology | Gene Expression Regulation - physiology | Rats | Male | Mice, Transgenic | Fear - physiology | Nucleus Accumbens - physiology | Mice, Knockout | Dose-Response Relationship, Drug | Cocaine - pharmacology | Self Administration | Animals | Conditioning, Operant - drug effects | Extinction, Psychological | Fear - psychology | Mice | Histone Deacetylases - physiology | Primary Cell Culture | Nucleus Accumbens - drug effects | Genes | Analysis | Cocaine | Neurosciences | Chromatin | Cues | Histone deacetylase | Transcription factors | Neurons | Memory | Genomes | Gene expression | Addictions | Nuclei | Nucleus accumbens | Learning | Drug self-administration | Fos protein | Rodents | Reinstatement | Addictive behaviors | Reinforcement | Behavior | Conditioning
Journal Article