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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2012, Volume 109, Issue 52, pp. 21360 - 21365
Ezh2 (Enhancer of zeste homolog 2) protein is the enzymatic component of the Polycomb repressive complex 2 (PRC2), which represses gene expression by... 
Cell growth | B lymphocytes | B cell lymphoma | Cell lines | Cell cycle | Stem cells | Histones | Methylation | English language learners | Genetic mutation | LYSINE 27 | B-CELLS | DEVELOPMENTAL REGULATORS | GENE | HISTONE H3 | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | LYMPHOMA | POLYCOMB | CANCER | SOMATIC MUTATIONS | Polycomb Repressive Complex 2 - antagonists & inhibitors | Small Molecule Libraries - pharmacology | Apoptosis - drug effects | Apoptosis - genetics | Gene Expression Profiling | Cell Cycle Checkpoints - genetics | Gene Expression Regulation, Neoplastic - drug effects | Fibroblasts - metabolism | Tumor Stem Cell Assay | Lymphoma, Large B-Cell, Diffuse - pathology | Up-Regulation - genetics | Down-Regulation - drug effects | Gene Knockout Techniques | Mutation - genetics | Down-Regulation - genetics | Enhancer of Zeste Homolog 2 Protein | Up-Regulation - drug effects | Small Molecule Libraries - chemistry | Phenotype | Animals | Histone-Lysine N-Methyltransferase - metabolism | Methylation - drug effects | Cell Cycle Checkpoints - drug effects | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Cell Line, Tumor | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Cell Proliferation - drug effects | Mice | Histones - metabolism | Polycomb Repressive Complex 2 - metabolism | Lymphoma, Large B-Cell, Diffuse - genetics | Cell proliferation | Development and progression | Care and treatment | Lymphomas | Research | Proteins | DNA methylation | Enzymes | Mutation | Gene expression | Index Medicus | Biological Sciences
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2015, Volume 17, Issue 5, pp. 627 - 638
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Oncogene, ISSN 0950-9232, 03/2017, Volume 36, Issue 13, pp. 1770 - 1778
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Journal Article
Acta Biomaterialia, ISSN 1742-7061, 12/2013, Volume 9, Issue 12, pp. 9547 - 9557
Journal Article
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7586, pp. 413 - 417
Triple-negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy(1-3). BET bromodomain... 
SELECTIVE-INHIBITION | SUPER-ENHANCERS | RNA-SEQ | SUBTYPES | INFLAMMATION | STRATEGY | MULTIDISCIPLINARY SCIENCES | CELL IDENTITY | C-MYC | PP2A | LEUKEMIA | Chromatin - metabolism | Transcription, Genetic - drug effects | Humans | Transcription Factors - deficiency | Triple Negative Breast Neoplasms - drug therapy | Genome, Human - drug effects | Nuclear Proteins - deficiency | Protein Binding - drug effects | Triple Negative Breast Neoplasms - pathology | Female | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Nuclear Proteins - genetics | Triazoles - therapeutic use | Cell Proliferation - genetics | Mediator Complex Subunit 1 - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Phosphoserine - metabolism | Genome, Human - genetics | Azepines - therapeutic use | Azepines - pharmacology | Binding, Competitive - drug effects | Transcription Factors - metabolism | Triazoles - pharmacology | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Triple Negative Breast Neoplasms - genetics | Epigenesis, Genetic - genetics | Triple Negative Breast Neoplasms - metabolism | Nuclear Proteins - antagonists & inhibitors | Protein Phosphatase 2 - metabolism | Proteomics | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Chromatin - genetics | Casein Kinase II - metabolism | Drug Resistance, Neoplasm - drug effects | Protein Structure, Tertiary - drug effects | Antimitotic agents | Enzyme inhibitors | Patient outcomes | Breast cancer | Dosage and administration | Drug therapy | Antineoplastic agents | Studies | Inhibitor drugs | Drug resistance | Gene expression | Drug dosages | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2012, Volume 18, Issue 10, pp. 1503 - 1510
Journal Article