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STEM CELLS, ISSN 1066-5099, 05/2015, Volume 33, Issue 5, pp. 1419 - 1433
Journal Article
Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 08/2017, Volume 16, Issue 8, pp. 1497 - 1510
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2015, Volume 52, pp. 188 - 196
Abstract A small subpopulation of pancreatic cancer cells with characteristics of stem cells drive tumour initiation, progression and metastasis. A better... 
Hematology, Oncology and Palliative Medicine | GABA | Sonic hedgehog | Stress neurotransmitters | Nicotinic receptors | Cancer stem cells | Pancreatic cancer | METASTASIS | ACETYLCHOLINE | ADENOCARCINOMA | DUCT EPITHELIAL-CELLS | PROLIFERATION | ONCOLOGY | PATHWAY | RESISTANCE | THERAPIES | EXPRESSION | PROGRESSION | Pancreatic Neoplasms - metabolism | Neoplastic Stem Cells - drug effects | gamma-Aminobutyric Acid - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Hedgehog Proteins - metabolism | Carcinoma, Pancreatic Ductal - genetics | Cell Self Renewal - drug effects | Nicotine - pharmacology | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Spheroids, Cellular | Nicotinic Agonists - pharmacology | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Pancreatic Neoplasms - pathology | gamma-Aminobutyric Acid - pharmacology | Pancreatic Neoplasms - genetics | Cell Separation - methods | Carcinoma, Pancreatic Ductal - pathology | Transcription Factors - metabolism | Carcinoma, Pancreatic Ductal - drug therapy | Signal Transduction - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Zinc Finger Protein GLI1 | Receptors, Nicotinic - genetics | Prevention | Epinephrine | Stem cells | Cancer | Nicotine | Index Medicus | sonic hedgehog | pancreatic cancer | cancer stem cells | stress neurotransmitters
Journal Article
Oncogene, ISSN 0950-9232, 09/2017, Volume 36, Issue 36, pp. 5145 - 5157
Retinoblastoma (RB) protein inactivation during tumor progression is often associated with acquisition of immature phenotypes and resistance to therapy.... 
COMPREHENSIVE MOLECULAR PORTRAITS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RETINOBLASTOMA TUMOR-SUPPRESSOR | DEFICIENT CELLS | CANCER STEM-CELLS | CELL BIOLOGY | BREAST-CANCER | INHIBITION | METABOLISM | ONCOLOGY | FATTY-ACID OXIDATION | IN-VIVO | GENETICS & HEREDITY | Apoptosis - drug effects | Humans | Drug Resistance, Neoplasm | Breast Neoplasms - metabolism | Cell Self Renewal - drug effects | Tumor Suppressor Protein p53 - physiology | Biomarkers, Tumor - metabolism | Female | Tumor Cells, Cultured | Fatty Acids - metabolism | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Fatty Acids - chemistry | Antineoplastic Agents, Hormonal - pharmacology | Interleukin-6 - genetics | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Metabolome | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Breast Neoplasms - drug therapy | Mice, Knockout | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - pathology | Cell Differentiation - drug effects | Retinoblastoma Protein - genetics | Tamoxifen - pharmacology | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Mice | Development and progression | Care and treatment | Genetic aspects | Retinoblastoma | Tumor proteins | Health aspects | Transcription factors | Sarcoma | Secretion | p53 Protein | Stat3 protein | Retinoblastoma protein | Endocrine therapy | JNK protein | Superoxide | Breast cancer | Tumor cell lines | Gene expression | Kinases | Interleukin 6 | Genotype & phenotype | Mitochondria | Feedback | Stem cells | Oxidation | Electron transport | Index Medicus
Journal Article
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 03/2019, Volume 10, Issue 1, pp. 1436 - 14
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2015, Volume 28, Issue 6, pp. 715 - 729
Mutations in the histone 3 variant H3.3 have been identified in one-third of pediatric glioblastomas (GBMs), but not in adult tumors. Here we show that H3.3 is... 
MALIGNANT GLIOMA | STEM-LIKE CELLS | INTERFERON-GAMMA | ONCOLOGY | HUMAN GLIOBLASTOMA | GENE-EXPRESSION | MYELOID-LEUKEMIA | DIFFERENTIATION | NEURAL PRECURSORS | PEDIATRIC GLIOBLASTOMA | TUMOR-INITIATING CELLS | CELL BIOLOGY | Cell Proliferation | Prognosis | Neoplastic Stem Cells - drug effects | Epigenesis, Genetic | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Child, Preschool | Gene Expression Profiling | Molecular Targeted Therapy | Brain Neoplasms - metabolism | Chromatin Assembly and Disassembly - drug effects | Cell Self Renewal - drug effects | DNA-Binding Proteins - metabolism | Young Adult | DNA Methylation | Transfection | Glioblastoma - genetics | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Drug Design | Neoplastic Stem Cells - pathology | Adult | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Cell Differentiation | Brain Neoplasms - mortality | Tumor Cells, Cultured | Child | Signal Transduction | Kaplan-Meier Estimate | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | DNA-Binding Proteins - genetics | Mice, SCID | Xenograft Model Antitumor Assays | Animals | Histones - genetics | Glioblastoma - pathology | Adolescent | Mice, Inbred NOD | Histones - metabolism | Mutation | Glioblastoma - drug therapy | Glioblastoma - mortality | Epigenetic inheritance | Chromatin | Analysis | Leukemia | Children's hospitals | Stem cells | Chromosomes | Stem cell research | Molecular genetics | Brain tumors | Index Medicus
Journal Article