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Cancer research (Chicago, Ill.), ISSN 0008-5472, 12/2011, Volume 71, Issue 23, pp. 7155 - 7167
... it. Because TGF-beta is a modifier of radiation responses, we conducted a preclinical study of the antitumor effects of the TGF-beta receptor (TGF beta R... 
EPITHELIAL-MESENCHYMAL TRANSITION | GLIOMA-CELLS | MIGRATION | APOPTOSIS | GROWTH-FACTOR-BETA | ONCOLOGY | PATHWAY | RADIORESISTANCE | CANCER STEM | MECHANISMS | EXPRESSION | Apoptosis - drug effects | Apoptosis - radiation effects | Neoplastic Stem Cells - drug effects | Humans | Brain Neoplasms - pathology | Smad2 Protein - antagonists & inhibitors | Glioblastoma - radiotherapy | Brain Neoplasms - metabolism | Neoplastic Stem Cells - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Neoplastic Stem Cells - pathology | Transforming Growth Factor beta - antagonists & inhibitors | Glioblastoma - metabolism | Signal Transduction - radiation effects | Brain Neoplasms - radiotherapy | Protein-Serine-Threonine Kinases - metabolism | Neoplastic Stem Cells - radiation effects | Pyrazoles - pharmacology | Microarray Analysis - methods | Mesenchymal Stromal Cells - drug effects | Neoplasm Invasiveness | Radiation-Sensitizing Agents - pharmacology | Smad2 Protein - metabolism | Brain Neoplasms - drug therapy | Mice, SCID | Radiation Tolerance - drug effects | Xenograft Model Antitumor Assays | Pyrroles - pharmacology | Animals | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Neovascularization, Pathologic - drug therapy | DNA Repair | Glioblastoma - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | DNA Damage | Glioblastoma - drug therapy | Transforming Growth Factor beta - metabolism | Cell Proliferation - radiation effects
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 9, pp. 3621 - 3626
The maintenance of functional chloroplasts in photosynthetic eukaryotes requires real-time coordination of the nuclear and plastid genomes. Tetrapyrroles play... 
Chloroplasts | Genes | Cell lines | Genomes | Bile pigments | Plants | Gene expression | Plastids | Chlorophylls | Plant cells | Iron homeostasis | Oxidative stress | RNA-Seq analysis | Biliverdin | Heme oxygenase | heme oxygenase | iron homeostasis | PHYTOCHROME CHROMOPHORE BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | STRESS-RESPONSE | LIGHT | REINHARDTII | NUCLEAR GENE-EXPRESSION | HEME OXYGENASES | GENOME REVEALS | biliverdin | SINGLET OXYGEN | MG-PROTOPORPHYRIN IX | oxidative stress | BILIVERDIN REDUCTASE | Chloroplasts - enzymology | Heme - metabolism | Gene Expression Profiling | Gene Regulatory Networks - drug effects | Biliverdine - pharmacology | Pigmentation - radiation effects | Chlamydomonas reinhardtii - genetics | Chlamydomonas reinhardtii - physiology | Pigmentation - genetics | Biocatalysis - drug effects | Light | Plants, Genetically Modified | Chloroplasts - radiation effects | Phycocyanin - biosynthesis | Signal Transduction - radiation effects | Chloroplasts - drug effects | Heme Oxygenase (Decyclizing) - metabolism | Iron - pharmacology | Heme Oxygenase (Decyclizing) - genetics | Biocatalysis - radiation effects | Phototrophic Processes - drug effects | Chlamydomonas reinhardtii - cytology | Gene Expression Regulation, Plant - radiation effects | Pigmentation - drug effects | Oxidoreductases - metabolism | Subcellular Fractions - drug effects | Oxidoreductases - genetics | Phycobilins - biosynthesis | Signal Transduction - genetics | Chlorophyll - metabolism | Mutation - genetics | Subcellular Fractions - metabolism | Bile Pigments - metabolism | Gene Expression Regulation, Plant - drug effects | Phenotype | Signal Transduction - drug effects | Genes, Plant - genetics | Phototrophic Processes - genetics | Chlamydomonas reinhardtii - enzymology | Subcellular Fractions - radiation effects | Gene Regulatory Networks - radiation effects | Physiological aspects | Research | Photosynthesis | Chlamydomonas | Pyrrole | Biological Sciences
Journal Article
JNCI : Journal of the National Cancer Institute, ISSN 0027-8874, 09/2016, Volume 108, Issue 9
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 01/2013, Volume 288, Issue 3, pp. 1603 - 1611
Deregulated cell survival under carcinogen-induced genotoxic stress is vital for cancer development... 
IRRADIATION | INHIBITION | GENE | UVB-INDUCED APOPTOSIS | PROTEIN-KINASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | TUMOR | AMPK PHOSPHORYLATION | DEGRADATION | Cell Transformation, Neoplastic - radiation effects | Autophagy - radiation effects | Keratinocytes - radiation effects | Sequestosome-1 Protein | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Lysosomes - metabolism | Ultraviolet Rays | Cell Cycle Proteins - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Signal Transduction - radiation effects | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Skin Neoplasms - pathology | Epidermis - metabolism | Epidermis - radiation effects | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Keratinocytes - cytology | Ataxia Telangiectasia Mutated Proteins | Cell Survival - radiation effects | Skin Neoplasms - metabolism | Phosphorylation - radiation effects | Animals | Histones - genetics | Fibroblasts - radiation effects | Keratinocytes - metabolism | Skin Neoplasms - genetics | Adaptor Proteins, Signal Transducing - genetics | Epidermal Cells | Fibroblasts - cytology | Gene Expression Regulation, Neoplastic - radiation effects | Mice | Apoptosis - physiology | DNA Damage | Enzyme Activation | Histones - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus | UVB | Molecular Bases of Disease | p38 | Cell Survival | Cell Death | Autophagy | p62 | Apoptosis | Cancer
Journal Article
PloS one, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e77203
.... The effects of radiation combined injury are potentially more lethal than either insult in isolation... 
METHICILLIN-RESISTANT | MORTALITY | MULTIPLE-ORGAN-FAILURE | CECAL LIGATION | MULTIDISCIPLINARY SCIENCES | GUT | MICE | SEPSIS | RESISTANT STAPHYLOCOCCUS-AUREUS | IONIZING-RADIATION | EXPOSURE | Intestinal Mucosa - radiation effects | Gamma Rays | Lung - microbiology | Proto-Oncogene Proteins c-bcl-2 - immunology | Whole-Body Counting | Radiation Injuries, Experimental - immunology | Staphylococcal Infections - pathology | Dendritic Cells - immunology | CD4-Positive T-Lymphocytes - radiation effects | Bronchoalveolar Lavage Fluid - immunology | Apoptosis - genetics | Staphylococcal Infections - complications | Bronchoalveolar Lavage Fluid - microbiology | Dendritic Cells - radiation effects | CD4-Positive T-Lymphocytes - immunology | CD8-Positive T-Lymphocytes - radiation effects | Methicillin-Resistant Staphylococcus aureus - pathogenicity | Radiation Injuries, Experimental - complications | Intestinal Mucosa - immunology | Killer Cells, Natural - immunology | Lung - radiation effects | Bronchoalveolar Lavage Fluid - cytology | Radiation Injuries, Experimental - mortality | Killer Cells, Natural - microbiology | B-Lymphocytes - microbiology | Gene Expression | B-Lymphocytes - radiation effects | CD4-Positive T-Lymphocytes - microbiology | CD8-Positive T-Lymphocytes - microbiology | Killer Cells, Natural - radiation effects | Staphylococcal Infections - immunology | Mice, Transgenic | Intestinal Mucosa - microbiology | Radiation Injuries, Experimental - pathology | Staphylococcal Infections - mortality | Methicillin-Resistant Staphylococcus aureus - growth & development | Animals | Apoptosis - immunology | B-Lymphocytes - immunology | Survival Analysis | Dendritic Cells - microbiology | Mice | CD8-Positive T-Lymphocytes - immunology | Proto-Oncogene Proteins c-bcl-2 - genetics | Lung - immunology | Infection | Ionizing radiation | Dendritic cells | Lymphocytes | Staphylococcus aureus infections | Genetic engineering | Health aspects | Staphylococcus aureus | Apoptosis | Detonation | Bcl-2 protein | CD8 antigen | Radiation | Drug resistance | Methicillin | Surgery | Neutropenia | Spleen | Medical research | Radiation effects | Digestive system | Mortality | Bombs | Survival | Studies | Secondary infection | Sepsis | Anesthesiology | Surgical outcomes | Animal models | Pneumonia | Physicians | Lymphocytes T | Infections | Interleukin 6 | Immunology | Epidermal growth factor | Granulocyte colony-stimulating factor | Intestine | Rodents | Radiation injuries | Bacteria | Trachea | Digestive tract | Injuries | Transgenic mice | Staphylococcus infections | I.R. radiation | CD4 antigen | Medicine | Lymphocytes B | Nuclear devices | Laboratory animals
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 84, pp. 25 - 41
..., adhesion molecules, and cell survival proteins is well documented [4] . Relying on its proven anti-oxidant and anti-inflammatory capabilities in restoring the various... 
Advanced Basic Science | Dentistry | Photodegradation | Phototoxicity | Curcumin | Apoptosis/necrosis | Photoprotection | Nanoformulation | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | MECHANISM | INDUCED APOPTOSIS | ENGINEERING, BIOMEDICAL | DNA-DAMAGE | MITOCHONDRIA | KERATINOCYTES | DEATH | BCL-2 | SUNLIGHT | BAX | DNA Breaks - drug effects | NIH 3T3 Cells | Reactive Oxygen Species - metabolism | Nanoparticles - chemistry | Apoptosis - drug effects | Apoptosis - radiation effects | Keratinocytes - radiation effects | Membrane Potential, Mitochondrial - radiation effects | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Membrane Potential, Mitochondrial - drug effects | RNA, Messenger - metabolism | DNA Breaks - radiation effects | Photosensitizing Agents - pharmacology | Ultraviolet Rays | Protective Agents - pharmacology | Cytoprotection - drug effects | Oxidative Stress - radiation effects | Signal Transduction - radiation effects | Proto-Oncogene Proteins c-akt - metabolism | Keratinocytes - enzymology | Keratinocytes - ultrastructure | Cell Membrane - drug effects | Cell Membrane - radiation effects | Cell Line | Cell Survival - drug effects | Lactic Acid - chemistry | RNA, Messenger - genetics | Curcumin - pharmacology | Absorption, Radiation | Cell Survival - radiation effects | Animals | Cell Cycle Checkpoints - radiation effects | Keratinocytes - drug effects | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Polyglycolic Acid - chemistry | Drug Liberation | Mice | Molecular Docking Simulation | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Nanoparticles | Genetic research | Analysis | Index Medicus | Biotechnology | Phosphorylation | Cascades | Sunlight | Exposure | Biological | Apoptosis
Journal Article
Development (Cambridge), ISSN 0950-1991, 05/2016, Volume 143, Issue 10, pp. 1697 - 1709
Journal Article
Journal Article