X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (55330) 55330
Book Review (15738) 15738
Publication (5258) 5258
Book / eBook (1332) 1332
Book Chapter (725) 725
Dissertation (146) 146
Conference Proceeding (125) 125
Newsletter (61) 61
Newspaper Article (25) 25
Magazine Article (19) 19
Reference (5) 5
Web Resource (3) 3
Data Set (2) 2
Paper (2) 2
Transcript (2) 2
Government Document (1) 1
Presentation (1) 1
Report (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (50042) 50042
humans (39418) 39418
animals (27189) 27189
oncology (18788) 18788
cancer (17072) 17072
mice (14207) 14207
female (12654) 12654
cell biology (10242) 10242
cell line, tumor (10203) 10203
male (9509) 9509
apoptosis (9254) 9254
expression (8252) 8252
biochemistry & molecular biology (8008) 8008
tumors (7761) 7761
research (7553) 7553
gene expression regulation, neoplastic (7548) 7548
gene expression (7350) 7350
proteins (6460) 6460
signal transduction (6353) 6353
cell transformation, neoplastic (5679) 5679
genetic aspects (5568) 5568
cell transformation, neoplastic - drug effects (5515) 5515
analysis (5137) 5137
health aspects (5124) 5124
metastasis (5122) 5122
cell proliferation (5004) 5004
cells (4925) 4925
cell line (4840) 4840
development and progression (4733) 4733
article (4435) 4435
stem cells (4332) 4332
care and treatment (4294) 4294
cell transformation, neoplastic - genetics (4238) 4238
mutation (4169) 4169
middle aged (4151) 4151
rats (4049) 4049
cells, cultured (4039) 4039
breast cancer (4030) 4030
antineoplastic agents - pharmacology (4004) 4004
physiological aspects (3889) 3889
growth (3767) 3767
cell cycle (3766) 3766
apoptosis - drug effects (3739) 3739
research article (3736) 3736
kinases (3663) 3663
breast-cancer (3654) 3654
medicine (3636) 3636
cell proliferation - drug effects (3623) 3623
gene expression regulation, neoplastic - drug effects (3595) 3595
chemotherapy (3565) 3565
activation (3521) 3521
gene-expression (3520) 3520
cell transformation, neoplastic - metabolism (3472) 3472
multidisciplinary sciences (3420) 3420
adult (3381) 3381
genes (3354) 3354
prognosis (3335) 3335
biology (3285) 3285
carcinogenesis (3271) 3271
aged (3251) 3251
phosphorylation (3221) 3221
genetics & heredity (3200) 3200
hematology (3164) 3164
tumor cells, cultured (3109) 3109
signal transduction - drug effects (2981) 2981
cell transformation, neoplastic - pathology (2956) 2956
pharmacology & pharmacy (2928) 2928
in-vitro (2875) 2875
review (2792) 2792
medicine, research & experimental (2782) 2782
proliferation (2746) 2746
pathology (2737) 2737
cell growth (2713) 2713
neoplasms - pathology (2710) 2710
immunohistochemistry (2642) 2642
neoplasms - genetics (2629) 2629
cell division - drug effects (2623) 2623
antineoplastic agents - therapeutic use (2611) 2611
mice, nude (2578) 2578
neoplasms - metabolism (2552) 2552
cancer research (2534) 2534
down-regulation (2488) 2488
tumorigenesis (2475) 2475
in-vivo (2467) 2467
carcinoma (2461) 2461
science (2452) 2452
inhibition (2360) 2360
rodents (2350) 2350
cancer therapies (2347) 2347
disease progression (2336) 2336
medicine & public health (2330) 2330
dose-response relationship, drug (2300) 2300
transfection (2275) 2275
nf-kappa-b (2247) 2247
transformation (2233) 2233
leukemia (2223) 2223
risk factors (2215) 2215
cell survival - drug effects (2196) 2196
blotting, western (2161) 2161
genetics (2135) 2135
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (1010) 1010
UofT at Mississauga - Stacks (86) 86
UTL at Downsview - May be requested (82) 82
UofT at Scarborough - Stacks (54) 54
Collection Dvlpm't (Acquisitions) - Closed Orders (52) 52
Collection Dvlpm't (Acquisitions) - Vendor file (40) 40
Online Resources - Online (38) 38
Earth Sciences (Noranda) - Stacks (27) 27
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (9) 9
Engineering & Comp. Sci. - Stacks (8) 8
Trinity College (John W Graham) - Stacks (8) 8
UofT at Scarborough - May be requested in 6-10 wks (6) 6
Gerstein Science - Circulation Desk (5) 5
Mt Sinai Hospital - Pathology (5) 5
Physics - Stacks (5) 5
Royal Ontario Museum - Stacks (5) 5
Dentistry (Harry R Abbott) - Stacks (4) 4
UofT at Scarborough - Withdrawn (4) 4
Chemistry (A D Allen) - Stacks (3) 3
Credit Valley Hospital - Stacks (3) 3
Gerstein Science - Missing (3) 3
St. Michael's Hospital - Circulation Desk (3) 3
St. Michael's Hospital - Stacks (3) 3
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (2) 2
Earth Sciences (Noranda) - Missing (2) 2
Gerstein Science - Not Returned (2) 2
Gerstein Science - Periodical Stacks (2) 2
Humber River Regional Hospital - Finch Stacks (2) 2
Markham Stouffville Hospital - Stacks (2) 2
OISE - Stacks (2) 2
Scarborough Hospital - General (2) 2
St. Michael's College (John M. Kelly) - 2nd Floor (2) 2
Toronto East General Hospital - Stacks (2) 2
Trinity College (John W Graham) - Storage (2) 2
Collection Dvlpm't (Acquisitions) - Reference (1) 1
Dentistry (Harry R Abbott) - May be requested (1) 1
Dentistry (Harry R Abbott) - Withdrawn (1) 1
Earth Sciences (Noranda) - Reference (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Gerstein Science - May be requested in 6-10 wks (1) 1
Gerstein Science - Reference (1) 1
Gerstein Science - Reference Desk (1) 1
Holland Bloorview Kids Rehabilitation - Stacks (1) 1
Mathematical Sciences - Stacks (1) 1
Missing (1) 1
New College (Ivey) - Stacks (1) 1
Physics - Missing (1) 1
Physics - Storage (1) 1
Providence Healthcare - Reference (1) 1
Providence Healthcare - Reserve desk (1) 1
Providence Healthcare - Stacks (1) 1
Scarborough Hospital - Closed Orders (1) 1
St Josephs Health Centre - General (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Reference (1) 1
UofT at Mississauga - Missing (1) 1
UofT at Mississauga - Reference (1) 1
UofT at Scarborough - May be requested (1) 1
UofT at Scarborough - Reference (1) 1
Victoria University E.J. Pratt - Stacks (1) 1
Women's College Hospital - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (56389) 56389
Russian (230) 230
Chinese (215) 215
German (200) 200
French (119) 119
Spanish (83) 83
Japanese (78) 78
Polish (42) 42
Italian (19) 19
Danish (9) 9
Czech (7) 7
Swedish (7) 7
Hungarian (6) 6
Arabic (3) 3
Romanian (3) 3
Korean (2) 2
Norwegian (2) 2
Slovak (2) 2
Ukrainian (2) 2
Bulgarian (1) 1
Dutch (1) 1
Finnish (1) 1
Nepali (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7571, pp. 131 - 135
Despite major advances in understanding the molecular and genetic basis of cancer, metastasis remains the cause of >90% of cancer-related mortality(1).... 
INHIBITION | COMMITMENT | MULTIDISCIPLINARY SCIENCES | GROWTH | GENES | MARKERS | IDENTIFICATION | FATE | TUMORS | TRANSCRIPTOME ANALYSIS | MAMMARY-GLAND | Neoplastic Stem Cells - drug effects | Epithelial Cells - drug effects | Humans | Gene Expression Profiling | Epithelial-Mesenchymal Transition - genetics | Cell Differentiation - genetics | Flow Cytometry | Neoplasm Metastasis - drug therapy | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Cyclin-Dependent Kinases - antagonists & inhibitors | Single-Cell Analysis | Disease Models, Animal | Cell Separation | Epithelial Cells - pathology | Mice, SCID | Breast Neoplasms - drug therapy | Disease Progression | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Differentiation - drug effects | Neoplasm Metastasis - pathology | Genes, myc - genetics | Cell Line, Tumor | Mice, Inbred NOD | Cell Proliferation - drug effects | Mesoderm - metabolism | Mice | Cell Transformation, Neoplastic - drug effects | Cell Cycle - drug effects | Cell Transformation, Neoplastic - pathology | Mesoderm - pathology | Stem cells | Cancer cells | Development and progression | Breast cancer | Metastasis | Observations | Health aspects | Bone marrow | Principal components analysis | Gene expression | Tumors | Apoptosis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 3, pp. 972 - 977
Metformin, the first-line drug for treating diabetes, inhibits cellular transformation and selectively kills cancer stem cells in breast cancer cell lines. In... 
T lymphocytes | Cell growth | Phosphorylation | Stem cells | Cell lines | Breast cancer | Diabetes | Heterologous transplantation | Tumors | Cancer | Cancer treatment | Cancer prevention | Inflammation | cancer treatment | RESPIRATORY-CHAIN | METABOLIC SYNDROME | ACTIVATION | cancer prevention | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | CYCLE ARREST | DECREASES | CHEMOTHERAPY | BREAST-CANCER | DIABETIC-PATIENTS | inflammation | AMPK | Inflammation - pathology | Neoplastic Stem Cells - drug effects | Humans | NF-kappa B - metabolism | Breast Neoplasms - metabolism | Inflammation - metabolism | Hypoglycemic Agents - administration & dosage | Neoplastic Stem Cells - metabolism | Anticarcinogenic Agents - administration & dosage | Neoplastic Stem Cells - pathology | Female | Stress, Physiological - drug effects | Metformin - administration & dosage | Anticarcinogenic Agents - pharmacology | STAT3 Transcription Factor - metabolism | Doxorubicin - administration & dosage | Cell Line | Metformin - pharmacology | Breast Neoplasms - drug therapy | Cell Transformation, Neoplastic - metabolism | Hypoglycemic Agents - pharmacology | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - pathology | Mice, Nude | Cell Line, Tumor | Feedback, Physiological - drug effects | Inflammation - prevention & control | Mice | Cell Transformation, Neoplastic - drug effects | Cell Transformation, Neoplastic - pathology | Prevention | Cancer cells | Physiological aspects | Dosage and administration | Hypoglycemic agents | Metformin | Research | Cell transformation | Health aspects | Signal transduction | Metabolism | Index Medicus | Biological Sciences
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7390, pp. 484 - 488
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 128, Issue 2, pp. 257 - 267
Assembly of the eIF4E/eIF4G complex has a central role in the regulation of gene expression at the level of translation initiation. This complex is regulated... 
FACTOR EIF-4E | HUMAN-DISEASE | MALIGNANT-TRANSFORMATION | CAP-DEPENDENT TRANSLATION | MESSENGER-RNA CAP | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING PROTEIN EIF4E | EUKARYOTIC TRANSLATION | SECONDARY STRUCTURE | MTOR INHIBITORS | CANCER-THERAPY | CELL BIOLOGY | Protein Binding - genetics | Humans | Nitro Compounds - chemistry | Eukaryotic Initiation Factor-4E - metabolism | Peptide Fragments - pharmacology | Eukaryotic Initiation Factor-4G - drug effects | Eukaryotic Initiation Factor-4G - metabolism | Fluorescence Polarization Immunoassay - methods | Thiazoles - isolation & purification | Antineoplastic Agents - isolation & purification | Cell Transformation, Neoplastic - genetics | Protein Binding - drug effects | Nitro Compounds - pharmacology | Antineoplastic Agents - pharmacology | Protein Biosynthesis - genetics | Gene Expression Regulation, Neoplastic - drug effects | Eukaryotic Initiation Factor-4E - genetics | Peptide Fragments - genetics | Gene Expression Regulation, Neoplastic - genetics | RNA, Messenger - drug effects | Drug Evaluation, Preclinical - methods | Oncogenes - genetics | Peptide Fragments - metabolism | Jurkat Cells | RNA, Messenger - genetics | Hydrazones | Models, Molecular | Antineoplastic Agents - chemistry | Cell Transformation, Neoplastic - metabolism | Eukaryotic Initiation Factor-4E - drug effects | Nitro Compounds - isolation & purification | Animals | Cell Line, Tumor | Oncogenes - drug effects | Feedback, Physiological - drug effects | Protein Biosynthesis - drug effects | Thiazoles - chemistry | Eukaryotic Initiation Factor-4G - genetics | Mice | Thiazoles - pharmacology | Cell Transformation, Neoplastic - drug effects | Feedback, Physiological - physiology | Cell Line, Transformed | Index Medicus | Peptide Fragments | Protein Biosynthesis | Gene Expression Regulation, Neoplastic | Eukaryotic Initiation Factor-4E | Chemical Sciences | Fluorescence Polarization Immunoassay | Life Sciences | Thiazoles | Drug Evaluation, Preclinical | Feedback, Biochemical | Oncogenes | Analytical chemistry | Biochemistry, Molecular Biology | Antineoplastic Agents | Organic chemistry | Eukaryotic Initiation Factor-4G | Cell Transformation, Neoplastic | Nitro Compounds | Protein Binding | RNA, Messenger
Journal Article
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7584, pp. 110 - 114
Gain-of-function IDH mutations are initiating events that define major clinical and prognostic classes of gliomas(1,2). Mutant IDH protein produces a new... 
MAINTENANCE | METHYLATION | LANDSCAPE | DEMETHYLATION | MULTIDISCIPLINARY SCIENCES | INTEGRATED GENOMIC ANALYSIS | ARCHITECTURE | PHENOTYPE | EXPRESSION | 2-HYDROXYGLUTARATE | PRINCIPLES | Chromatin - metabolism | Up-Regulation | Humans | Glioma - genetics | Base Sequence | Glioma - pathology | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Binding Sites | Chromatin - drug effects | Repressor Proteins - metabolism | Oncogenes - genetics | Insulator Elements - genetics | Glioma - enzymology | Chromosomal Proteins, Non-Histone - metabolism | Cell Cycle Proteins - metabolism | Cells, Cultured | Isocitrate Dehydrogenase - genetics | DNA Methylation - genetics | Down-Regulation - drug effects | Mutation - genetics | CRISPR-Cas Systems - genetics | Insulator Elements - drug effects | Phenotype | Isocitrate Dehydrogenase - chemistry | Receptor, Platelet-Derived Growth Factor alpha - genetics | CCCTC-Binding Factor | CpG Islands - genetics | Protein Binding | Isocitrate Dehydrogenase - metabolism | Cell Proliferation - drug effects | Enhancer Elements, Genetic - genetics | Glutarates - metabolism | Cell Transformation, Neoplastic - drug effects | Chromatin - genetics | DNA Methylation - drug effects | Glioma - drug therapy | Complications and side effects | Care and treatment | Platelet-derived growth factor | Gliomas | Analysis | Influence | Genetic aspects | Research | Methylation | Oncogenes | DNA methylation | Epigenetics | Genomes | Mutation | Gene expression | Binding sites | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 03/2013, Volume 32, Issue 13, pp. 1616 - 1625
HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and overexpression is correlated with poor... 
HOTAIR | Cell cycle progression | Pro-oncogenic | Invasion | Prognostic | ACTIVATION | pro-oncogenic | PROTEIN | CHROMATIN | DUCTAL ADENOCARCINOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | CELL BIOLOGY | prognostic | INTERFERON | invasion | LONG NONCODING RNA | REPRESSION | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | cell cycle progression | MIRNAS | Prognosis | Pancreatic Neoplasms - diagnosis | Humans | Transplantation, Heterologous | RNA, Long Noncoding - physiology | Carcinoma, Pancreatic Ductal - genetics | Gene Knockdown Techniques | Cell Transformation, Neoplastic - genetics | Biomarkers, Tumor - metabolism | Carcinoma, Pancreatic Ductal - diagnosis | Female | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - physiology | Pancreatic Neoplasms - pathology | RNA, Small Interfering - pharmacology | Pancreatic Neoplasms - genetics | Biomarkers, Tumor - physiology | RNA, Long Noncoding - genetics | Carcinoma, Pancreatic Ductal - pathology | Animals | Cell Line, Tumor | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Mice | Cell Transformation, Neoplastic - drug effects | RNA, Long Noncoding - antagonists & inhibitors | RNA, Long Noncoding - metabolism | RNA | Pancreatic cancer | Physiological aspects | Genetic aspects | Research | Gene expression | Oncology | Cell cycle | Tumors | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 5, pp. 1462 - 1476
Abstract Glioblastomas (GBMs) are the most common primary brain tumors with poor prognosis. CD133 has been considered a putative marker of cancer stem cells... 
Advanced Basic Science | Dentistry | miR145 | Drug-resistance | Polyurethane-short branch polyethylenimine | Glioblastoma | MiR145 | GLIOMA-CELLS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | TRANSFECTION EFFICIENCY | IDENTIFICATION | TUMOR-INITIATING CELLS | SOX2 | OCT4 | BIODEGRADABLE POLYURETHANE | RESISTANCE | EXPRESSION | CD133 | Dacarbazine - therapeutic use | Neoplastic Stem Cells - drug effects | Humans | Middle Aged | 3' Untranslated Regions - genetics | Molecular Sequence Data | Polyurethanes - chemical synthesis | Male | MicroRNAs - metabolism | Gene Expression Profiling | Glioblastoma - radiotherapy | SOXB1 Transcription Factors - metabolism | Glioblastoma - genetics | Neoplastic Stem Cells - metabolism | Dacarbazine - pharmacology | Base Sequence | Polyethyleneimine - chemistry | Dacarbazine - analogs & derivatives | Neoplastic Stem Cells - pathology | Female | Gene Expression Regulation, Neoplastic - drug effects | Polyethyleneimine - chemical synthesis | Gene Transfer Techniques | Polyurethanes - chemistry | Down-Regulation - drug effects | Down-Regulation - genetics | Radiation Tolerance - drug effects | Polyethyleneimine - analogs & derivatives | Glioblastoma - pathology | Octamer Transcription Factor-3 - metabolism | Aged | MicroRNAs - genetics | Cell Transformation, Neoplastic - drug effects | Cell Transformation, Neoplastic - pathology | Glioblastoma - drug therapy | Drug Resistance, Neoplasm - drug effects | Medical colleges | Care and treatment | Biological products | Brain tumors | Genes | Drug resistance | Prevention | MicroRNA | Gliomas | Nuclear radiation | Analysis | Stem cells | Cancer | Index Medicus
Journal Article