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1. Full Text Relationship between [14 C]MeAIB uptake and amino acid transporter family gene expression levels or proliferative activity in a pilot study in human carcinoma cells: comparison with [3 H]Methionine uptake
by Kagawa, Shinya and Nishii, Ryuichi and Higashi, Tatsuya and Yamauchi, Hiroshi and Ogawa, Emi and Okudaira, Hiroyuki and Kobayashi, Masato and Yoshimoto, Mitsuyoshi and Shikano, Naoto and Kawai, Keiichi
Nuclear Medicine and Biology, ISSN 0969-8051, 2017, Volume 49, pp. 8 - 15
Abstract Introduction To clarify the difference between system A and L amino acid transport imaging in PET clinical imaging, we focused on the use of α-[ N... 
Radiology | MeAIB | Amino acid transporters | System A | Met | Proliferative activity | Flt | FDG-PET | SYSTEM | DIAGNOSIS | GLUTAMINE | TUMOR-CELLS | MAMMALIAN-CELLS | Fit | POSITRON-EMISSION-TOMOGRAPHY | MeAlB | PROSTATE-CANCER | IN-VIVO | CHINESE PATIENTS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | beta-Alanine - metabolism | Pilot Projects | Biological Transport | Methionine - metabolism | Humans | beta-Alanine - pharmacology | Amino Acid Transport Systems - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Positron-Emission Tomography | Gene Expression Regulation, Neoplastic - drug effects | beta-Alanine - analogs & derivatives | Genetic research | Amino acids | Genetic aspects | Carcinoma | Gene expression | Cancer | Lung cancer | Genes | Colorectal cancer
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2. Full Text [Ga-68]PSMA-HBED uptake mimicking lymph node metastasis in coeliac ganglia: an important pitfall in clinical practice
by Krohn, Thomas and Verburg, Frederik A and Pufe, Thomas and Neuhuber, Winfried and Vogg, Aneas and Heinzel, Alexander and Mottaghy, Felix M and Behrendt, Florian F
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 02/2015, Volume 42, Issue 2, pp. 210 - 214
To determine the frequency of seemingly pathological retroperitoneal uptake in the location of the coeliac ganglia in patients undergoing [68Ga]PSMA-HBED... 
Immunohistochemistry | 68 GaPSMA-HBED PET/CT | Medicine & Public Health | Orthopedics | Pitfall | Oncology | Nuclear Medicine | Imaging / Radiology | Cardiology | Prostate cancer | Coeliac ganglion | GaPSMA-HBED PET/CT | GA-68-LABELED PSMA LIGAND | DIAGNOSIS | PET/CT | RECURRENT PROSTATE-CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Oligopeptides | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | False Positive Reactions | Edetic Acid - analogs & derivatives | Multimodal Imaging | Lymphatic Metastasis - diagnostic imaging | Celiac Plexus - diagnostic imaging | Aged, 80 and over | Prostatic Neoplasms - diagnostic imaging | Aged | Radiopharmaceuticals | PET imaging | Tracers (Biology) | Sport-utility vehicles | Metastasis | Cells | Tomography | Lymphatic system | Medical imaging | Medical diagnosis
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3. Full Text Pretreatment Tumor 18F-FDG Uptake Improves Risk Stratification Beyond RECIST 1.1 in Patients With Advanced Nonsquamous Non–Small-Cell Lung Cancer: FDG Uptake and Risk Stratification
by Moon, Seung Hwan and Sun, Jong-Mu and Ahn, Jin Seok and Park, Keunchil and Ahn, Myung-Ju and Choi, Joon Young
Clinical Nuclear Medicine, ISSN 0363-9762, 02/2019, Volume 44, Issue 2, pp. e60 - e67
PURPOSEThis study investigated the prognostic role of tumor F-FDG uptake on pretreatment scans as an independent indicator and whether its addition improves... 
RECIST 1.1 | risk stratification | F-FDG PET/CT | SUV | prognosis | non-small-cell lung cancer | SURVIVAL | CRITERIA | F-18-FDG PET/CT | BIOMARKER | STAGE | SUVmax | PARAMETERS | PROGNOSTIC VALUE | MAINTENANCE THERAPY | CHEMOTHERAPY | POSITRON-EMISSION-TOMOGRAPHY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | Prognosis | Research | Lung cancer, Non-small cell | Risk assessment | Analysis
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4. Full Text [18 F]FDG-PET Standard Uptake Value as a Metabolic Predictor of Bone Marrow Response to Radiation: Impact on Acute and Late Hematological Toxicity in Cervical Cancer Patients Treated With Chemoradiation Therapy
by Elicin, Olgun, MD and Callaway, Sharon, BS and Prior, John O., MD, PhD and Bourhis, Jean, MD, PhD and Ozsahin, Mahmut, MD, PhD and Herrera, Fernanda G., MD
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2014, Volume 90, Issue 5, pp. 1099 - 1107
Purpose To quantify the relationship between bone marrow (BM) response to radiation and radiation dose by using18 F-labeled fluorodeoxyglucose positron... 
Radiology | Hematology, Oncology and Palliative Medicine | SURVIVAL | CONSENSUS GUIDELINES | DELINEATION | CLINICAL TARGET VOLUME | CISPLATIN | ONCOLOGY | CONCURRENT CHEMOTHERAPY | INTENSITY-MODULATED RADIOTHERAPY | PELVIC RADIOTHERAPY | EMISSION-TOMOGRAPHY | PARAMETERS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Fluorodeoxyglucose F18 - pharmacokinetics | Chemoradiotherapy - adverse effects | Humans | Middle Aged | Tomography, X-Ray Computed - methods | Bone Marrow - radiation effects | Carcinoma, Squamous Cell - diagnostic imaging | Bone Marrow Cells - diagnostic imaging | Cisplatin - administration & dosage | Multimodal Imaging | Radiation-Sensitizing Agents - administration & dosage | Bone Marrow - metabolism | Aged, 80 and over | Adult | Female | Bone Marrow - diagnostic imaging | Retrospective Studies | Uterine Cervical Neoplasms - therapy | Radiotherapy Dosage | Acute Disease | Chemoradiotherapy - methods | Radiopharmaceuticals - pharmacokinetics | Radiotherapy, Intensity-Modulated - methods | Carcinoma, Squamous Cell - therapy | Bone Marrow Cells - radiation effects | Positron-Emission Tomography - methods | Blood Cell Count | Regression Analysis | Adenocarcinoma - therapy | Uterine Cervical Neoplasms - diagnostic imaging | Aged | Adenocarcinoma - diagnostic imaging | Bone Marrow Cells - metabolism | Cancer patients | Care and treatment | PET imaging | Radiation | Sport-utility vehicles | Standards | Cervical cancer | Cancer | DIAGNOSIS | PATIENTS | NEOPLASMS | FLUORODEOXYGLUCOSE | BONE MARROW | RADIATION DOSES | TOXICITY | SKELETON | POSITRON COMPUTED TOMOGRAPHY | UPTAKE | RADIOLOGY AND NUCLEAR MEDICINE | BLOOD CELLS | RADIOTHERAPY | FLUORINE 18
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5. Full Text Mitochondrial calcium uptake
by George S. B. Williams and Liron Boyman and Aristide C. Chikando and Ramzi J. Khairallah and W. J. Lederer
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 26, pp. 10479 - 10486
Calcium (Ca²⁺) uptake into the mitochondrial matrix is critically important to cellular function. As a regulator of matrix Ca²⁺ levels, this flux influences... 
Mitochondria | Calcium | PERSPECTIVE | Neurons | Sarcoplasmic reticulum | Liver | Physiological regulation | Implementation maturity model | Liver cells | Skeletal muscle | Muscle tissues | NCX | SERCA | Microdomain | NCLX | Inner mitochondrial membrane | ALLOSTERIC REGULATION | inner mitochondrial membrane | ESSENTIAL COMPONENT | ROOT GANGLION NEURONS | MULTIDISCIPLINARY SCIENCES | CARDIAC MYOCYTES | microdomain | MOTOR-NERVE TERMINALS | MATHEMATICAL-MODEL | LIVER-MITOCHONDRIA | SKELETAL-MUSCLE FIBERS | CA2+ UPTAKE | RAT VENTRICULAR MYOCYTES | Animals | Mitochondria, Heart - metabolism | Calcium Channels - metabolism | Calcium - metabolism | Calcium Signaling - physiology | Humans | Mitochondria, Muscle - metabolism | Mitochondria - metabolism | Calcium metabolism | Research | Properties | Mitochondrial membranes | Biological Sciences
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6. Full Text Raman microscopy for cellular investigations — From single cell imaging to drug carrier uptake visualization
by Kann, Birthe and Offerhaus, Herman L and Windbergs, Maike and Otto, Cees
Advanced Drug Delivery Reviews, ISSN 0169-409X, 07/2015, Volume 89, pp. 71 - 90
Progress in advanced therapeutic concepts requires the development of appropriate carrier systems for intracellular drug delivery. Consequently, analysis of... 
Drug carriers | Interaction between cell and carrier | Cell imaging | Intracellular fate of carriers | Nanomaterials | Spontaneous Raman microscopy | Chemically selective visualization | Uptake | GOLD NANOPARTICLES | PROTEIN DISTRIBUTION | POLY(LACTIDE-CO-GLYCOLIDE) NANOPARTICLES | LIVE CELLS | BREAST-CANCER | FLUORESCENCE MICROSCOPY | EPITHELIAL-CELLS | EMBRYONIC STEM-CELLS | INTRACELLULAR DELIVERY | PHARMACOLOGY & PHARMACY | LIVING CELLS | Cell Physiological Phenomena - physiology | Spectrum Analysis, Raman - methods | Nanostructures | Humans | Drug Carriers - chemistry | Drug Delivery Systems | Drugs | Drug delivery systems | Raman spectroscopy | Microscope and microscopy | Investigations | Vehicles | Medical research | Medicine, Experimental | Research institutes
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7. Full Text [18 F]fluorodeoxyglucose Uptake Patterns in Lung Before Radiotherapy Identify Areas More Susceptible to Radiation-Induced Lung Toxicity in Non-Small-Cell Lung Cancer Patients
by Petit, Steven F., M.Sc and van Elmpt, Wouter J.C., Ph.D and Oberije, Cary J.G., M.Sc and Vegt, Erik, M.D and Dingemans, Anne-Marie C., Ph.D and Lambin, Philippe, M.D., Ph.D and Dekker, André L.A.J., Ph.D and De Ruysscher, Dirk, M.D., Ph.D
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 11/2011, Volume 81, Issue 3, pp. 698 - 705
Purpose Our hypothesis was that pretreatment inflammation in the lung makes pulmonary tissue more susceptible to radiation damage. The relationship between... 
Radiology | Hematology, Oncology and Palliative Medicine | Radiation-induced lung toxicity (RILT) | Positron emission tomography (PET) | Pneumonitis | Dyspnea | Fluorodeoxyglucose (FDG) | Lung | MANAGEMENT | TISSUE DOSE CONSTRAINTS | INDUCED PNEUMONITIS | DISORDERS | RISK | CHEMOTHERAPY | POSITRON-EMISSION-TOMOGRAPHY | PRESCRIPTION | ONCOLOGY | INFECTION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | Carcinoma, Non-Small-Cell Lung - radiotherapy | Fluorodeoxyglucose F18 - pharmacokinetics | Age Factors | Humans | Lung Neoplasms - metabolism | Middle Aged | Lung Neoplasms - radiotherapy | Male | Tomography, X-Ray Computed | Dyspnea - etiology | Lung - diagnostic imaging | Positron-Emission Tomography | Chemoradiotherapy | Radiation Pneumonitis - metabolism | Multimodal Imaging - methods | Aged, 80 and over | Adult | Female | Lung - radiation effects | Lung - metabolism | Retrospective Studies | Odds Ratio | Radiopharmaceuticals - pharmacokinetics | Carcinoma, Non-Small-Cell Lung - metabolism | Radiation Pneumonitis - diagnostic imaging | Logistic Models | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Cancer patients | Lung cancer, Non-small cell | Radiotherapy | Developmental biology | Risk factors | Radiation | Toxicity | Lung cancer | Tomography | Inflammation | Respiration | Age | Tumors | Index Medicus | TOMOGRAPHY | HOURS LIVING RADIOISOTOPES | EMISSION COMPUTED TOMOGRAPHY | LUNGS | RADIATION EFFECTS | FLUORODEOXYGLUCOSE | RADIATION DOSES | MEDICINE | CAT SCANNING | ANTIMETABOLITES | FLUORINE ISOTOPES | THERAPY | NANOSECONDS LIVING RADIOISOTOPES | POSITRON COMPUTED TOMOGRAPHY | HYPOTHESIS | DRUGS | BETA DECAY RADIOISOTOPES | RADIOLOGY AND NUCLEAR MEDICINE | PNEUMONITIS | RADIOTHERAPY | LIGHT NUCLEI | RADIOLOGY | BETA-PLUS DECAY RADIOISOTOPES | DIAGNOSTIC TECHNIQUES | NEOPLASMS | ISOMERIC TRANSITION ISOTOPES | RADIOISOTOPES | TOXICITY | SYMPTOMS | COMPUTERIZED TOMOGRAPHY | NUCLEAR MEDICINE | ISOTOPES | ORGANS | DISEASES | NUCLEI | DOSES | RESPIRATORY SYSTEM | INFLAMMATION | ODD-ODD NUCLEI | BODY | PATHOLOGICAL CHANGES | FLUORINE 18 | HAZARDS
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8. Full Text Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
by Zhang, Yi-Nan and Poon, Wilson and Tavares, Anthony J and McGilvray, Ian D and Chan, Warren C.W
Journal of Controlled Release, ISSN 0168-3659, 10/2016, Volume 240, pp. 332 - 348
30–99% of administered nanoparticles will accumulate and sequester in the liver after administration into the body. This results in reduced delivery to the... 
Nanoparticle | Liver | Hepatobiliary clearance | Macrophage | IRON-OXIDE NANOPARTICLES | POLY(GAMMA-GLUTAMIC ACID)-POLY(LACTIDE) NANOPARTICLES | TARGETED DRUG-DELIVERY | MESOPOROUS SILICA NANOPARTICLES | SERUM-ALBUMIN NANOPARTICLES | IN-VIVO BIODISTRIBUTION | CHEMISTRY, MULTIDISCIPLINARY | SINGLE INTRAVENOUS-INJECTION | HEPATIC STELLATE CELLS | PHARMACOLOGY & PHARMACY | RED-BLOOD-CELLS | LIPOSOME-MEDIATED DEPLETION | Nanoparticles - chemistry | Hepatobiliary Elimination | Humans | Liver - metabolism | Nanoparticles - toxicity | Kupffer Cells - drug effects | Animals | Liver - drug effects | Biliary Tract - metabolism | Nanoparticles - metabolism | Surface Properties | Kupffer Cells - metabolism | Biliary Tract - drug effects | Nanotechnology | Phosphates | Ethylene glycol | Anthracyclines | Transferrin | Biological products | Low density lipoproteins | Retinoids | Glutamate | Ethanolamines | Glycine | Silica | Monosaccharides | Proteins | Epidermal growth factor | Ferric oxide | Fluorescein | Hyaluronic acid | Mass spectrometry | Sugars | Biomedical engineering | Protein binding | Index Medicus
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