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Neurochemical Research, ISSN 0364-3190, 10/2019, Volume 44, Issue 10, pp. 2288 - 2300
Brain astrocytes are considered to be highly glycolytic, but these cells also produce ATP via mitochondrial oxidative phosphorylation. To investigate how a... 
Neurochemistry | Biochemistry, general | Neurology | Neurosciences | Mitochondria | Biomedicine | Lactate | Glycolysis | Glucose | Metabolism | Cell Biology | Brain | Phosphorylation | Incubation | Toxicity | Astrocytes | Lactate dehydrogenase | Efavirenz | Survival | L-Lactate dehydrogenase | Glucose metabolism | Nuclear fuels | Depletion | Oxidative phosphorylation | Antimycin A | Lactic acid | Metformin | Localization | ATP | Viability
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1339 - 1353
Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in patients with Alzheimer's disease (AD). Although a connection... 
MAMMALIAN TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | INTRANASAL INSULIN | RECEPTOR-DEPENDENT MECHANISM | AMYLOID-BETA | AXONAL-TRANSPORT | TNF-ALPHA | SYNAPTIC PLASTICITY | CULTURED HIPPOCAMPAL-NEURONS | PEPTIDE OLIGOMERS | TRANSGENIC MICE | Phosphorylation | Insulin - physiology | Humans | Middle Aged | Macaca fascicularis | Memory Disorders - metabolism | Male | Hippocampus - drug effects | Insulin Receptor Substrate Proteins - metabolism | Infliximab | Alzheimer Disease - prevention & control | Aged, 80 and over | Female | Neurons - metabolism | Neurons - drug effects | Alzheimer Disease - psychology | Hypoglycemic Agents - therapeutic use | Cells, Cultured - drug effects | Amyloid beta-Peptides - toxicity | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Insulin Resistance | Rats | Mice, Transgenic | Hippocampus - pathology | Hippocampus - cytology | Maze Learning - drug effects | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Hippocampus - metabolism | Memory Disorders - prevention & control | Animals | MAP Kinase Signaling System - drug effects | Memory Disorders - etiology | Alzheimer Disease - metabolism | Venoms - therapeutic use | Aged | Cells, Cultured - metabolism | Mice | Protein Processing, Post-Translational | Venoms - pharmacology | Alzheimer Disease - genetics | Peptides - therapeutic use
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2001, Volume 2, Issue 11, pp. 1032 - 1039
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 11/2011, Volume 109, Issue 11, pp. 1259 - 1268
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1271 - 1282
The cytolcine IL-12 induces IFN-gamma production by T and NK cells. In preclinical models, it contributes to antitumor immunity. However, in clinical testing,... 
CXC CHEMOKINE RECEPTOR-5 | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR | INTERLEUKIN-12 | INNATE IMMUNE CELLS | ANTIGEN-SPECIFIC CD8 | ANTITUMOR IMMUNITY | HEPATITIS-C | HCV INFECTION | PD-1 EXPRESSION | DISEASE PROGRESSION | T-Lymphocyte Subsets - immunology | Lymphoma, Follicular - metabolism | Prognosis | Humans | Neoplasm Proteins - physiology | Interleukin-12 - physiology | Monocytes - metabolism | Neoplasm Proteins - antagonists & inhibitors | Interleukin-12 - blood | Membrane Proteins - physiology | T-Lymphocyte Subsets - drug effects | Programmed Cell Death 1 Receptor - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | B-Lymphocytes - metabolism | Interleukin-12 - biosynthesis | Interleukin-12 - pharmacology | Cells, Cultured - drug effects | Lymphoma, Follicular - pathology | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Tumor Cells, Cultured - drug effects | CD4-Positive T-Lymphocytes - metabolism | Kaplan-Meier Estimate | Lymphoma, Follicular - mortality | Transcription Factors - biosynthesis | Tumor Cells, Cultured - metabolism | CD4 Lymphocyte Count | Transcription Factors - genetics | Hepatitis A Virus Cellular Receptor 2 | Monocytes - drug effects | B-Lymphocytes - drug effects | Disease-Free Survival | Membrane Proteins - biosynthesis | T-Lymphocyte Subsets - pathology | Lymphoma, Follicular - immunology | Membrane Proteins - antagonists & inhibitors | T-Lymphocyte Subsets - metabolism | Lipopolysaccharides - pharmacology | Cells, Cultured - metabolism | Programmed Cell Death 1 Receptor - genetics | CD4-Positive T-Lymphocytes - drug effects | Interferon-gamma - biosynthesis | Interferon-gamma - pharmacology | Care and treatment | Interleukin-12 | Genetic aspects | Research | Non-Hodgkin's lymphomas | Diagnosis | Gene expression | T cells | Health aspects
Journal Article