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NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 3987 - 18
In contrast to our extensive knowledge on ubiquitin polymer signaling, we are severely limited in our understanding of poly-SUMO signaling. We set out to... 
MODIFIER SUMO | FORMS | COMPLEX | COMPUTATIONAL PLATFORM | UBIQUITIN LIGASE | MULTIDISCIPLINARY SCIENCES | HP1 | IDENTIFICATION | CENP-A | SUMOYLATION | REVEALS | Cell proliferation | Ubiquitin | DNA damage | Proteinase | Centromeres | Substrates | Proteins | Signaling | Protease | Proteolysis | Micronuclei | Proteasomes | Polymers | Deoxyribonucleic acid--DNA | Functional groups
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 02/2019, Volume 9, Issue 1, pp. 3001 - 14
Spiders are an ancient and extremely diverse animal order. They show a considerable diversity of genome sizes, karyotypes and sex chromosomes, which makes them... 
ARANEAE | GC CONTENT EVOLUTION | FAMILIES | MULTIDISCIPLINARY SCIENCES | SIZE | DYSDERIDAE | ARACHNIDA | INVERTED MEIOSIS | HOLOCENTRIC CHROMOSOMES | SEX-CHROMOSOMES | CENTROMERE | Sex chromosomes | Polyploidy | Spiders | Sex | Karyotypes | Evolution | Meiosis | Genomes | Chromosomes
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11259 - 10
Centromere genomics remain poorly characterized in cancer, due to technologic limitations in sequencing and bioinformatics methodologies that make... 
CHROMOSOME | RECOMBINATION | GENE | MULTIDISCIPLINARY SCIENCES | IN-SITU HYBRIDIZATION | INTEGRATIVE CLINICAL GENOMICS | CELL-LINES | CENP-A | REPEATS | ENDOGENOUS RETROVIRAL ELEMENTS | CYTOGENETIC ANALYSIS | Centromeres | Cell lines | Malignancy | Tumor cell lines | Phylogeny | Gene conversion | Bioinformatics | Cancer
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 6795 - 10
The three dimensional organization of genomes remains mostly unknown due to their high degree of condensation. Biophysical studies predict that condensation... 
REPLICATION | CHROMATIN DOMAINS | LINKING NUMBER | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | KNOTTED DNA | MODEL | SPATIAL-ORGANIZATION | DNA-MOLECULES | PRINCIPLES | GENOME | Telomeres | Chromatin | Computer applications | Centromeres | Genomes | Mathematical models | Telomerase | Condensation | Chromosomes | Conformation | Fibers
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 7624 - 12
Rad21/Scc1 is a subunit of the cohesin complex implicated in gene regulation as well as sister chromatid cohesion. The level of Rad21/Scc1 must be controlled... 
SISTER-CHROMATID COHESION | LOCALIZATION | CELLS | SMC PROTEINS | NUCLEAR | PHOSPHORYLATION | MICROTUBULES | KINETOCHORE | RAD21 | MULTIDISCIPLINARY SCIENCES | CENTROMERES | Nuclear division | Phosphoprotein phosphatase | Mitosis | Gene regulation | CUT protein | Gene expression | Defects | Proteins | Insects | Proteasomes | Protein phosphatase | Cohesin | Mutation | Spindles
Journal Article
BMC GENOMICS, ISSN 1471-2164, 04/2019, Volume 20, Issue 1, pp. 262 - 17
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 4046 - 18
Nucleosomes containing the histone H3 variant CENP-A are the epigenetic mark of centromeres, the kinetochore assembly sites required for chromosome... 
SCM3 | MIS18 | MAINTENANCE | GENETIC-CODE | AMINO-ACID | COMPLEX | DOMAIN | NUCLEOSOMES | CHROMATIN | MULTIDISCIPLINARY SCIENCES | GLUTATHIONE-S-TRANSFERASE | Centromeres | Nucleosomes | Crosslinking | Helices | Heredity | Dimers | Chromosomes | Assembly | Binding sites | Deposition | Histone H3 | Recruitment
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 12542 - 10
Hydatidiform moles are abnormal pregnancies, which show trophoblastic hyperplasia. Most often, the nuclear genome in complete hydatidiform moles (CHMs) is... 
DIAGNOSIS | PARENTAL ORIGIN | RISK | COMPLETE HYDATIDIFORM MOLE | TRIPLOIDY | MULTIDISCIPLINARY SCIENCES | Zygosity | Gene frequency | Sperm | Hyperplasia | Genomes | Single-nucleotide polymorphism | Chromosomes | Polymorphism
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 12629 - 8
The centromere is important for segregation of chromosomes during cell division in eukaryotes. Its destabilization results in chromosomal missegregation,... 
ORGANIZATION | EVOLUTION | SUBFAMILIES | SEQUENCE VARIATION | CHROMATIN | ALIGNMENT | MULTIDISCIPLINARY SCIENCES | HUMAN CENTROMERE | CENP-A | REPETITIVE DNA | PROGRAM | DNA probes | Nucleotide sequence | Congenital defects | Centromeres | Cell division | Aneuploidy | Genomes | Satellite DNA | Down's syndrome | Chromosome 21 | Cytogenetics | Chromosomes | Deoxyribonucleic acid--DNA
Journal Article
Nature communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 175 - 10
CENP-A is the histone H3 variant necessary to specify the location of all eukaryotic centromeres via its CENP-A targeting domain and either one of its terminal... 
SER68 | DOMAIN | CHROMATIN | RECOGNITION | MECHANISM | MULTIDISCIPLINARY SCIENCES | NUCLEOSOME | Centromere - physiology | Phosphorylation | HeLa Cells | Humans | Gene Editing | Centromere Protein A - metabolism | Gene targeting | Serine | Centromeres | Post-translation | Viability | Histone H3
Journal Article