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The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2017, Volume 102, Issue 3, pp. 810 - 821
We found serum lipid profiles changed in women with PCOS. Obesity and compensatory hyperinsulinemia promoted the metabolism of arachidonic acid and other PUFAs, whereas androgen had an inhibitory effect. Abstract Context... 
POLYCYSTIC-OVARY-SYNDROME | IONIZATION-MASS-SPECTROMETRY | RISK-FACTORS | TESTOSTERONE | BIOLOGICAL SAMPLES | ENDOCRINOLOGY & METABOLISM | IMPAIRED GLUCOSE-TOLERANCE | NONALCOHOLIC STEATOHEPATITIS | FAT-CELL LIPOLYSIS | OLDER CHINESE | OBESE WOMEN | Arachidonic Acid - metabolism | Gas Chromatography-Mass Spectrometry | Linoleic Acid - metabolism | Humans | Dehydroepiandrosterone Sulfate - metabolism | Case-Control Studies | Young Adult | Testosterone - metabolism | Polycystic Ovary Syndrome - complications | Diet, High-Fat | Mass Spectrometry | Chromatography, Liquid | Adult | Female | Hyperandrogenism - metabolism | Fatty Acids - metabolism | Phosphatidylglycerols - metabolism | Disease Models, Animal | Hyperinsulinism - metabolism | Ceramides - metabolism | Hyperinsulinism - complications | Polycystic Ovary Syndrome - metabolism | Cholesterol, HDL - metabolism | Obesity - complications | Eicosapentaenoic Acid - metabolism | Rats | Sex Hormone-Binding Globulin - metabolism | Lipid Metabolism | Fatty Acids, Unsaturated - metabolism | Rats, Sprague-Dawley | Obesity - metabolism | Triglycerides - metabolism | Hyperandrogenism - complications | Insulin - metabolism | Animals | Cholesterol, LDL - metabolism | Phosphatidic Acids - metabolism | Androgens - metabolism | Blood Glucose - metabolism | Docosahexaenoic Acids - metabolism | Polycystic ovary syndrome | Obesity | Hyperinsulinemia | Lecithin | Polyunsaturated fatty acids | Lipids | Mass spectroscopy | Liquid chromatography | Phospholipids | Metabolism | Arachidonic acid | Insulin | Fatty acids | Patients | Chromatography | Biological activity | Subgroups | Gas chromatography | Androgens | Molecular modelling | Metabolites | Lipid metabolism | Mass spectrometry | Metabolic disorders
Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2012, Volume 62, Issue 2, pp. 401 - 410
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2014, Volume 79, pp. 275 - 283
Abstract Background Obesity leads to metabolic heart disease (MHD) that is associated with a pathologic increase in myocardial fatty acid (FA) uptake and... 
Cardiovascular | Obesity | Metabolic heart disease | Mitochondria | Lipid excess | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PROLIFERATOR-ACTIVATED RECEPTOR | KINASE-C | FATTY-ACIDS | CELL BIOLOGY | REDUCES DIABETIC CARDIOMYOPATHY | SKELETAL-MUSCLE | LIPOTOXIC CARDIOMYOPATHY | FAILING HEART | COACTIVATOR PGC-1 | TRANSCRIPTIONAL CONTROL | Mitochondria, Heart - ultrastructure | Phosphorylation | Mitochondria, Heart - metabolism | Carnitine - metabolism | RNA, Messenger - metabolism | Fatty Acid Transport Proteins - metabolism | Diglycerides - metabolism | Protein Kinase C - metabolism | Adenosine Triphosphate - metabolism | Myocardium - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Carnitine - analogs & derivatives | Proto-Oncogene Proteins c-akt - metabolism | Myocardium - ultrastructure | Ceramides - metabolism | Sphingomyelins - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Oxygen Consumption | Lipids - adverse effects | Myocardium - pathology | Organ Specificity | Hydrogen Peroxide - metabolism | Catalase - metabolism | Transcription Factors - metabolism | Animals | Electron Transport Complex II - metabolism | Models, Biological | Cyclic AMP Response Element-Binding Protein - metabolism | Myocytes, Cardiac - metabolism | Mice | PPAR alpha - metabolism | Fatty acids | Analysis | Mitochondrial DNA | Index Medicus | Metabolic Heart Disease | Lipid Excess
Journal Article
Circulation (New York, N.Y.), ISSN 1524-4539, 2012, Volume 125, Issue 23, pp. 2844 - 2853
Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2016, Volume 65, Issue 3, pp. 610 - 618
The innate immune cell sensor leucine-rich-containing family, pyrin domain containing 3 (NLRP3) inflammasome controls the activation of caspase-1, and the... 
ACTIVATION | ADIPOCYTES | METABOLISM | ADIPONECTIN | CERAMIDE CONTENT | ENDOCRINOLOGY & METABOLISM | SENSITIVITY | NLRP3 INFLAMMASOME | HEPATIC STEATOSIS | EXPRESSION | INDUCED INSULIN-RESISTANCE | Fatty Acid Synthase, Type I - genetics | Sirtuin 1 - metabolism | Glucose Transporter Type 4 - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Obesity - immunology | Humans | Leptin - metabolism | Caspase 1 - metabolism | Male | Gene Expression Profiling | Interleukin-1beta - genetics | PPAR gamma - metabolism | Sirtuin 1 - genetics | Acetyl-CoA Carboxylase - genetics | Subcutaneous Fat - immunology | Subcutaneous Fat - metabolism | Lipogenesis - genetics | Interleukin-1beta - metabolism | Adiponectin - genetics | Adiponectin - metabolism | Female | Adipogenesis - genetics | Child | Lipoprotein Lipase - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Sterol Regulatory Element Binding Protein 1 - metabolism | PPAR gamma - genetics | Glucose Transporter Type 4 - genetics | Inflammasomes | Lipoprotein Lipase - genetics | Down-Regulation | Insulin Resistance | Toll-Like Receptor 4 - genetics | Intra-Abdominal Fat - metabolism | Fatty Acid Synthase, Type I - metabolism | Subcutaneous Fat - pathology | Toll-Like Receptor 4 - metabolism | Abdomen | Obesity - metabolism | Carrier Proteins - genetics | Magnetic Resonance Imaging | Sterol Regulatory Element Binding Protein 1 - genetics | Caspase 1 - genetics | Adolescent | Intra-Abdominal Fat - pathology | Acetyl-CoA Carboxylase - metabolism | Adipose tissues | Overweight persons | Care and treatment | Inflammation | Research | Health aspects | Metabolism
Journal Article
The Plant cell, ISSN 1532-298X, 2011, Volume 23, Issue 6, pp. 2362 - 2378
Sphingolipids are a class of structural membrane lipids involved in membrane trafficking and cell polarity. Functional analysis of the ceramide synthase family... 
Ceramides | Cell aggregates | Auxins | Lipids | Sphingolipids | Cell membranes | Plants | Fatty acids | Plant cells | Seedlings | CERAMIDE SYNTHASE | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT-CELLS | SACCHAROMYCES-CEREVISIAE | PLANT SCIENCES | CELL BIOLOGY | AUXIN TRANSPORT | F-SP LYCOPERSICI | FUMONISIN B-1 | LIPID RAFTS | TRANS-GOLGI NETWORK | ROOT-SYSTEM ARCHITECTURE | Oxidoreductases - antagonists & inhibitors | Sphingolipids - chemistry | Cell Polarity | Arabidopsis - physiology | Fumonisins - metabolism | Humans | Molecular Sequence Data | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | Intracellular Membranes - ultrastructure | Arabidopsis Proteins - metabolism | Isoenzymes - metabolism | Cell Membrane - metabolism | Membrane Proteins - metabolism | Amino Acid Sequence | Arabidopsis Proteins - genetics | Ceramides - metabolism | Enzyme Inhibitors - metabolism | Indoleacetic Acids - metabolism | Oxidoreductases - metabolism | Isoenzymes - genetics | Membrane Proteins - genetics | Oxidoreductases - genetics | Arabidopsis - cytology | Sphingolipids - metabolism | Ceramides - chemistry | Protein Synthesis Inhibitors - metabolism | Brefeldin A - metabolism | Arabidopsis - genetics | Secretory Pathway - physiology | Sequence Alignment | Animals | Membrane Proteins - chemistry | Recombinant Fusion Proteins - genetics | Intracellular Membranes - metabolism | Arabidopsis thaliana | Physiological aspects | Genetic aspects | Cell Membrane | Enzyme Inhibitors | Secretory Pathway | Intracellular Membranes | Brefeldin A | Recombinant Fusion Proteins | Life Sciences | Arabidopsis Proteins | Vegetal Biology | Protein Synthesis Inhibitors | Fumonisins | Isoenzymes | Arabidopsis | Membrane Proteins | Oxidoreductases | Indoleacetic Acids | Endosomes
Journal Article
Journal Article
Diabetes care, ISSN 1935-5548, 2018, Volume 41, Issue 8, pp. 1732 - 1739
OBJECTIVE Nonalcoholic fatty liver disease (i.e., increased intrahepatic triglyceride [IHTG] content), predisposes to type 2 diabetes and cardiovascular... 
WOMEN | OBESITY | DIET | ACIDS | INSULIN-RESISTANCE | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | ENDOTOXEMIA | WEIGHT-GAIN | LIPOPROTEINS | ADIPOSE-TISSUE | Fatty Acids - adverse effects | Overweight - complications | Humans | Liver - metabolism | Middle Aged | Insulin Resistance | Non-alcoholic Fatty Liver Disease - etiology | Male | Dietary Fats, Unsaturated - adverse effects | Non-alcoholic Fatty Liver Disease - metabolism | Monosaccharides - adverse effects | Feeding Behavior - physiology | Adipose Tissue - metabolism | Overweight - metabolism | Carbohydrate Metabolism - physiology | Dietary Fats, Unsaturated - metabolism | Insulin - metabolism | Triglycerides - blood | Adult | Female | Monosaccharides - metabolism | Weight Gain | Fatty Acids - metabolism | Lipid Metabolism - physiology | Health aspects | Saturated fatty acids | Liver | Medical and Health Sciences | endotoxemia | monosaccharide | body weight gain | Dietary Fats, Unsaturated | Overweight | saturated fatty acid | female | obesity | Endocrinology and Diabetes | clinical trial | nonalcoholic fatty liver | liver | food composition | adipose tissue | physiology | Clinical Medicine | Conference Paper | metabolism | adult | sugar | edible oil | gene expression | male | complication | triacylglycerol | Fatty Acids | insulin | carbohydrate metabolism | Medicin och hälsovetenskap | lipid metabolism | feeding behavior | fatty acid | Klinisk medicin | Monosaccharides | ceramide derivative | unsaturated fatty acid | dietary intake | clinical article | Endokrinologi och diabetes | Non-alcoholic Fatty Liver Disease | human | insulin resistance | proton nuclear magnetic resonance | hyperinsulinemia | Triglycerides | middle aged | blood | controlled study | lipid blood level | lipolysis | macronutrient | high calorie diet
Journal Article