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Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 2458 - 8
Journal Article
Journal Article
Journal Article
2005, Proteases in biology and disease, ISBN 0387231005, Volume 3., xvi, 383
In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to... 
Brain | Brain chemistry | Pathophysiology | Proteinase | Clinical & internal medicine | Life Sciences | Biochemistry, general | Neurosciences
Book
Human Gene Therapy, ISSN 1043-0342, 03/2018, Volume 29, Issue 3, pp. 312 - 326
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2009, Volume 240, Issue 2, pp. 132 - 142
Organophosphorus ester-induced delayed neurotoxicity (OPIDN) is a neurodegenerative disorder characterized by ataxia progressing to paralysis with a... 
Peripheral nervous system | CREB | Diisopropylphosphorofluoridate | β-Tubulins | pCREB | Neurodegeneration | PKA | Organophosphate-induced delayed neurotoxicity | Anticholinergics. Central nervous system | OPIDN | ACIDIC PROTEIN GFAP | MESSENGER-RNA EXPRESSION | C-FOS | beta-Tubulins | PHOSPHOROFLUORIDATE (DFP)-TREATED HEN | DIISOPROPYL PHOSPHOROFLUORIDATE | ALTERED TIME-COURSE | NEUROPATHY TARGET ESTERASE | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | TOXICOLOGY | INDUCED DELAYED NEUROTOXICITY | POSTTRANSLATIONAL MODIFICATION | Immunohistochemistry | Phosphorylation | Cholinesterase Inhibitors - toxicity | Spinal Cord - drug effects | Neurodegenerative Diseases - prevention & control | Central Nervous System - pathology | Tubulin - genetics | RNA, Messenger - metabolism | Tubulin - metabolism | Neurotoxicity Syndromes - pathology | Time Factors | Isoflurophate - toxicity | Female | Antidotes - pharmacology | Cerebrum - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Neurodegenerative Diseases - pathology | Spinal Cord - enzymology | Atropine - pharmacology | Neurotoxicity Syndromes - prevention & control | Blotting, Western | Disease Progression | Neurotoxicity Syndromes - etiology | Cerebrum - enzymology | Neurotoxicity Syndromes - enzymology | Blotting, Northern | Animals | Neurodegenerative Diseases - chemically induced | Signal Transduction - drug effects | Chickens | Cyclic AMP Response Element-Binding Protein - metabolism | Central Nervous System - drug effects | Central Nervous System - enzymology | Neurodegenerative Diseases - enzymology | Index Medicus
Journal Article
Human & Experimental Toxicology, ISSN 0960-3271, 8/2017, Volume 36, Issue 8, pp. 854 - 866
Journal Article
Journal Article
Journal Article
International Journal of Toxicology, ISSN 1091-5818, 7/2014, Volume 33, Issue 4, pp. 325 - 331
This study demonstrates that aspartame consumption and insulin treatment in a juvenile diabetic rat model leads to increase in cytochrome P450 (CYP) 2E1 and... 
cytochrome P450 | insulin | brain | aspartame | diabetes | OXIDATIVE STRESS | XENOBIOTIC METABOLISM | INCREASES | MELLITUS | CYTOCHROME-P450 2E1 | ENZYMES | LIVER | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | TOXICOLOGY | EXPRESSION | Cytochrome P-450 CYP3A Inducers - therapeutic use | Non-Nutritive Sweeteners - therapeutic use | Cytochrome P-450 CYP2E1 Inducers - therapeutic use | Liver - enzymology | Rats, Wistar | Cerebellum - drug effects | Diabetes Mellitus, Type 1 - metabolism | Cytochrome P-450 CYP2E1 Inducers - adverse effects | Male | Cerebellum - enzymology | Cytochrome P-450 CYP2E1 - metabolism | Cytochrome P-450 CYP3A Inducers - adverse effects | Non-Nutritive Sweeteners - adverse effects | Liver - drug effects | Cytochrome P-450 CYP3A - chemistry | Enzyme Induction - drug effects | Neurons - drug effects | Cytochrome P-450 CYP2E1 - chemistry | Cerebrum - drug effects | Hypoglycemic Agents - therapeutic use | Hyperglycemia - prevention & control | Aspartame - adverse effects | Aspartame - therapeutic use | Nerve Tissue Proteins - agonists | Random Allocation | Combined Modality Therapy - adverse effects | Organ Specificity | Diabetes Mellitus, Type 1 - drug therapy | Nerve Tissue Proteins - metabolism | Cerebrum - enzymology | Animals | Cytochrome P-450 CYP3A - metabolism | Diabetes Mellitus, Type 1 - blood | Neurons - enzymology | Diabetes Mellitus, Type 1 - diet therapy | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Insulin - therapeutic use
Journal Article