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American Journal of Managed Care, ISSN 1088-0224, 2014, Volume 20, Issue 3, pp. e90 - e97
Objectives: A "chiral switch" occurs in the pharmaceutical market when a drug made up of 2 enantiomer forms is replaced with a purified single-enantiomer... 
MEDICATION | NAMES | MULTICENTER | EROSIVE ESOPHAGITIS | OMEPRAZOLE | RANDOMIZED CONTROLLED-TRIAL | 8-WEEK COMPARATIVE TRIAL | MEDICINE, GENERAL & INTERNAL | COST | HEALTH CARE SCIENCES & SERVICES | DOUBLE-BLIND | HEALTH POLICY & SERVICES | HEALTH | Proton Pump Inhibitors - economics | Formoterol Fumarate | Hypnotics and Sedatives - chemistry | Medicaid - economics | Stereoisomerism | United States | Humans | Dexmethylphenidate Hydrochloride - chemistry | Drugs, Generic - economics | Piperazines - economics | Esomeprazole - chemistry | Drug Approval | Piperazines - chemistry | Esomeprazole - economics | Eszopiclone | Azabicyclo Compounds - chemistry | Benzhydryl Compounds - chemistry | Antidotes - economics | Bronchodilator Agents - chemistry | Levoleucovorin - chemistry | Histamine H1 Antagonists, Non-Sedating - economics | Dexmethylphenidate Hydrochloride - economics | Dexlansoprazole - chemistry | Retrospective Studies | Central Nervous System Stimulants - economics | United States Food and Drug Administration | Wakefulness-Promoting Agents - chemistry | Levoleucovorin - economics | Antidotes - chemistry | Bronchodilator Agents - economics | Azabicyclo Compounds - economics | Benzhydryl Compounds - economics | Cetirizine - chemistry | Cetirizine - economics | Ethanolamines - economics | Ethanolamines - chemistry | Patents as Topic | Hypnotics and Sedatives - economics | Wakefulness-Promoting Agents - economics | Drug Prescriptions - statistics & numerical data | Proton Pump Inhibitors - chemistry | Central Nervous System Stimulants - chemistry | Dexlansoprazole - economics | Histamine H1 Antagonists, Non-Sedating - chemistry
Journal Article
Chirality, ISSN 0899-0042, 03/2014, Volume 26, Issue 3, pp. 136 - 143
ABSTRACT Solid phase extraction (SPE)‐chiral separation of the important drugs pheniramine, oxybutynin, cetirizine, and brinzolamide was achieved on the C18... 
modeling | SPE‐chiral‐HPLC | mechanism of separation | human plasma | SPE-chiral-HPLC | CHEMISTRY, ANALYTICAL | CHEMISTRY, MEDICINAL | CHEMISTRY, ORGANIC | GUINEA-PIG | EXCRETION | DIHYDROCHLORIDE | BETA-ADRENERGIC BLOCKERS | ENANTIOSELECTIVE DETERMINATION | LIQUID-CHROMATOGRAPHY | PHARMACOLOGY & PHARMACY | HUMAN URINE | HPLC | LEVOCETIRIZINE | Pharmaceutical Preparations - isolation & purification | Mandelic Acids - blood | Pharmaceutical Preparations - blood | Chromatography, High Pressure Liquid - methods | Pheniramine - chemistry | Stereoisomerism | Humans | Molecular Conformation | Sulfonamides - blood | Sulfonamides - isolation & purification | Amylose - chemistry | Cetirizine - blood | Pheniramine - blood | Mandelic Acids - isolation & purification | Phenylcarbamates - chemistry | Reproducibility of Results | Sulfonamides - chemistry | Thiazines - isolation & purification | Cetirizine - chemistry | Models, Molecular | Pheniramine - isolation & purification | Thiazines - blood | Amylose - analogs & derivatives | Thiazines - chemistry | Mandelic Acids - chemistry | Solid Phase Extraction - methods | Pharmaceutical Preparations - chemistry | Cetirizine - isolation & purification | Drugs | Oxybutynin | Enantiomers | Analysis | Chromatography | Separation | Phases | Computer simulation | Cartridges | Chirality | Mathematical models
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 08/2011, Volume 100, Issue 8, pp. 3177 - 3185
Journal Article
Drug Development and Industrial Pharmacy, ISSN 0363-9045, 10/2012, Volume 38, Issue 10, pp. 1280 - 1288
A novel coated gastric floating drug-delivery system (GFDDS) of bergenin (BN) and cetirizine dihydrochloride (CET) was developed. First, the pharmacodynamic... 
Bergenin | immediate-release coating | pharmacodynamics | extended-release core tablets | gastric floating drug-delivery system | in vivo gamma scintigraphy | cetirizine dihydrochloride | Gastric floating drug-delivery system | Cetirizine dihydrochloride | Pharmacodynamics | Extended-release core tablets | Immediate-release coating | IN-VITRO | CHEMISTRY, MEDICINAL | PHARMACOLOGY & PHARMACY | RELEASE | HYDROCHLORIDE | Chemistry, Pharmaceutical - methods | Cetirizine - pharmacology | Methylcellulose - analogs & derivatives | Motor Activity - drug effects | Male | Tablets - pharmacology | Stomach - metabolism | Antitussive Agents - pharmacology | Benzopyrans - chemistry | Absorption | Excipients - chemistry | Female | Benzopyrans - pharmacology | Anti-Asthmatic Agents - chemistry | Anti-Asthmatic Agents - pharmacology | Expectorants - chemistry | Tablets - administration & dosage | Guinea Pigs | Cetirizine - chemistry | Coated Materials, Biocompatible - administration & dosage | Coated Materials, Biocompatible - chemistry | Methylcellulose - chemistry | Antitussive Agents - chemistry | Benzopyrans - administration & dosage | Animals | Antitussive Agents - administration & dosage | Hypromellose Derivatives | Expectorants - administration & dosage | Cetirizine - administration & dosage | Radionuclide Imaging - methods | Tablets - chemistry | Expectorants - pharmacology | Mice | Anti-Asthmatic Agents - administration & dosage | Kinetics | Sodium Bicarbonate - chemistry | Delayed-Action Preparations | Drug Delivery Systems - methods
Journal Article
Talanta, ISSN 0039-9140, 11/2013, Volume 116, pp. 743 - 752
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2004, Volume 126, Issue 26, pp. 8128 - 8129
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2010, Volume 132, Issue 7, pp. 2124 - 2125
Journal Article
Journal Article
Journal Article