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Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 537, Issue 7619, pp. 229 - 233
.... and Trypanosoma brucei spp., respectively. These parasites have similar biology and genomic sequence, suggesting that all three diseases could be cured with drugs that modulate the activity of a conserved parasite target(2... 
SYSTEM | POSACONAZOLE | GENE | TRYPANOSOMA-CRUZI | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | RANDOMIZED-TRIAL | INFECTION | CURE | BORTEZOMIB | BENZNIDAZOLE | Triazoles - adverse effects | Trypanosomiasis, African - drug therapy | Chagas Disease - parasitology | Species Specificity | Chymotrypsin - metabolism | Triazoles - chemistry | Humans | Kinetoplastida - drug effects | Molecular Targeted Therapy | Pyrimidines - chemistry | Proteasome Endopeptidase Complex - drug effects | Inhibitory Concentration 50 | Female | Molecular Structure | Disease Models, Animal | Triazoles - therapeutic use | Proteasome Inhibitors - pharmacology | Leishmaniasis - drug therapy | Proteasome Inhibitors - classification | Pyrimidines - pharmacology | Kinetoplastida - enzymology | Proteasome Inhibitors - adverse effects | Proteasome Inhibitors - therapeutic use | Triazoles - pharmacology | Trypanosomiasis, African - parasitology | Animals | Pyrimidines - therapeutic use | Chagas Disease - drug therapy | Pyrimidines - adverse effects | Chymotrypsin - antagonists & inhibitors | Leishmaniasis - parasitology | Mice | Care and treatment | Leishmaniasis | Chagas' disease | Proteins | Protozoa | Cell growth | Inhibitor drugs | Parasitic diseases | Parasites | Drug therapy
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 8, p. e0135556
Journal Article
PLoS neglected tropical diseases, ISSN 1935-2735, 2019, Volume 13, Issue 7, p. e0007602
TGF-beta involvement in Chagas disease cardiomyopathy has been clearly demonstrated... 
CELLS | GROWTH-FACTOR-BETA | PATHWAY | CARDIOMYOPATHY | MICE | MYOCARDITIS | MECHANISMS | CARDIOMYOCYTES | TRYPANOSOMA-CRUZI INFECTION | PARASITOLOGY | TROPICAL MEDICINE | BENZNIDAZOLE | Fibrosis - drug therapy | Pyrazoles - therapeutic use | Chagas Cardiomyopathy - parasitology | Connexin 43 - metabolism | Mice, Inbred C57BL | Parasite Load | Heart Conduction System - drug effects | Chagas Cardiomyopathy - drug therapy | Chagas Cardiomyopathy - pathology | Animals | Benzamides - therapeutic use | Heart - parasitology | Heart - drug effects | Transforming Growth Factor beta - antagonists & inhibitors | Trypanosoma cruzi - drug effects | Female | Trypanocidal Agents - therapeutic use | Mice | Chronic Disease | Disease Models, Animal | Heart | Conduction | Cardiac arrhythmia | Therapy | Schedules | Transcription | Arrhythmia | Laboratories | Cardiomyopathy | Tissue inhibitor of metalloproteinase 4 | Cardiovascular disease | Infections | Connexin 43 | Parasites | Tissue inhibitor of metalloproteinase 2 | Tissues | Dosage | Tissue inhibitor of metalloproteinase 1 | Signal transduction | Extracellular matrix | Matrix protein | Heart diseases | Plaques | Vector-borne diseases | Protozoa | Cardiomyocytes | CD3 antigen | Extracellular | Coronary artery disease | Gelatinase B | Strain | Heart rate | Signaling | Inhibitors | Fibrosis | Chagas' disease | Cardiovascular diseases | Cell migration | Life Sciences
Journal Article
Journal Article