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1. The chemistry of chalcones and related compounds
by Dhar, Durga Nath
xiii, 285
Chalcones
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2. Full Text Publisher Correction: Evolution of chalcone isomerase from a noncatalytic ancestor
by Kaltenbach, Miriam and Burke, Jason R and Dindo, Mirco and Pabis, Anna and Munsberg, Fabian S and Rabin, Avigayel and Kamerlin, Shina C. L and Noel, Joseph P and Tawfik, Dan S
Nature Chemical Biology, ISSN 1552-4450, 05/2018, Volume 14, Issue 10, pp. 1 - 988
In the version of this article originally published, the number for the equal contributions footnote was missing for Miriam Kaltenbach and Jason R. Burke in... 
Chalcone isomerase
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3. Full Text Synthesis and antibacterial activity of some heterocyclic chalcone analogues alone and in combination with antibiotics
by Tran, Thanh-Dao and Nguyen, Thi-Thao-Nhu and Do, Tuong-Ha and Huynh, Thi-Ngoc-Phuong and Tran, Cat-Dong and Thai, Khac-Minh
Molecules (Basel, Switzerland), ISSN 1420-3049, 2012, Volume 17, Issue 6, pp. 6684 - 6696
A series of simple heterocyclic chalcone analogues have been synthesized by Claisen Schmidt condensation reactions between substituted benzaldehydes and... 
synthesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | antibacterial | FLAVONOIDS | RESISTANT STAPHYLOCOCCUS-AUREUS | CHEMISTRY, MULTIDISCIPLINARY | heterocyclic chalcone analogues | chalcone | METHICILLIN-RESISTANT | MRSA | PRENYLATED CHALCONES | synergitic activity | CYTOTOXICITY | DERIVATIVES | antibiotics combination | Anti-Bacterial Agents - chemical synthesis | Drug Synergism | Microbial Sensitivity Tests | Chalcone - chemistry | Chalcone - pharmacology | Chalcone - analogs & derivatives | Anti-Bacterial Agents - chemistry | Anti-Bacterial Agents - pharmacology | Structure-Activity Relationship | Staphylococcus aureus - drug effects | Chalcone - chemical synthesis
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4. Full Text Synthesis, biological evaluation and molecular docking of novel chalcone–coumarin hybrids as anticancer and antimalarial agents
by Pingaew, Ratchanok and Saekee, Amporn and Mandi, Prasit and Nantasenamat, Chanin and Prachayasittikul, Supaluk and Prachayasittikul, Virapong and Ruchirawat, Somsak
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2014, Volume 85, pp. 65 - 76
A new series of chalcone–coumarin derivatives ( – ) linked by the 1,2,3-triazole ring were synthesized through the azide/alkyne dipolar cycloaddition. Hybrid... 
Cytotoxicity | Triazole | Antimalarial activity | Coumarin | Chalcone | Molecular docking | DESIGN | CHEMISTRY, MEDICINAL | COLORIMETRIC ASSAY | INVITRO | INHIBITORY-ACTIVITY | PLASMODIUM-FALCIPARUM | GROWTH | CHEMISTRY | DERIVATIVES | Cysteine Endopeptidases - chemistry | Antimalarials - metabolism | Chalcone - chemistry | Chemistry Techniques, Synthetic | Triazoles - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Coumarins - chemistry | Plasmodium falciparum - drug effects | Antineoplastic Agents - chemistry | Antimalarials - pharmacology | Antineoplastic Agents - metabolism | Tubulin - metabolism | Chalcone - pharmacology | Cysteine Endopeptidases - metabolism | Antimalarials - chemistry | Chalcone - metabolism | Cell Line, Tumor | Protein Conformation | Antineoplastic Agents - pharmacology | Molecular Docking Simulation | Tubulin - chemistry | Chalcone - chemical synthesis | Antimalarials - chemical synthesis | Care and treatment | Malaria | Triazoles | Etoposide | Colchicine | Data mining | Cancer | Index Medicus
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5. Full Text Chalcone derivatives: Promising starting points for drug design
by Gomes, Marcelo N and Muratov, Eugene N and Pereira, Maristela and Peixoto, Josana C and Rosseto, Lucimar P and Cravo, Pedro V. L and Andrade, Carolina H and Neves, Bruno J
Molecules, ISSN 1420-3049, 08/2017, Volume 22, Issue 8, p. 1210
Medicinal chemists continue to be fascinated by chalcone derivatives because of their simple chemistry, ease of hydrogen atom manipulation, straightforward... 
Chalcone derivatives | Molecular modification strategies | Chalcone synthesis | Natural products | Computer-assisted drug design | molecular modification strategies | chalcone derivatives | CHEMISTRY, ORGANIC | BIOISOSTERIC REPLACEMENT | STRUCTURE-BASED PHARMACOPHORES | MOLECULAR DOCKING | chalcone synthesis | FINGERPRINT SIMILARITY SEARCH | FREE-ENERGY SIMULATIONS | MEDICINAL CHEMISTRY | natural products | computer-assisted drug design | VENOUS LYMPHATIC INSUFFICIENCY | PROTEIN-LIGAND DOCKING | BIOLOGICAL EVALUATION | ASSAY INTERFERENCE COMPOUNDS | Prodrugs - chemical synthesis | Prodrugs - chemistry | Chalcone - chemistry | Chalcone - analogs & derivatives | Chalcone - chemical synthesis | Drug Design | Design | Drugs | Chemists | Derivatives | Hybridization | Drug discovery | Drug development | Chemical synthesis | Design optimization
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6. Exploring pharmacological significance of chalcone scaffold: A review
by Sahu, N.K and Balbhadra, S.S and Choudhary, J and Kohli, D.V
Current Medicinal Chemistry, ISSN 0929-8673, 01/2012, Volume 19, Issue 2, pp. 209 - 225
Chalcones (1,3-diaryl-2-propen-1-ones) and their heterocyclic analogues, belong to the flavonoid family, which possess a number of interesting biological... 
α,β-unsaturated ketone | Antimalarial | Xanthohumol | Anticancer activity | Licochalcone | Chalcone | Butein | ANTIINFLAMMATORY ACTIVITY | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORY-ACTIVITY | butein | alpha,beta-unsaturated ketone | METHOXYLATED CHALCONES | TYROSINASE INHIBITORS | antimalarial | chalcone | IN-VITRO | PLASMODIUM-FALCIPARUM | BIOLOGICAL EVALUATION | ANTIMALARIAL ACTIVITY | PHARMACOLOGY & PHARMACY | anticancer activity | xanthohumol | NF-KAPPA-B | QUINOLINYL CHALCONES | Antioxidants - chemistry | Anti-Inflammatory Agents - pharmacology | Anti-Infective Agents - pharmacology | Enzyme Inhibitors - pharmacology | Hypoglycemic Agents - chemistry | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Hypoglycemic Agents - pharmacology | Anti-Inflammatory Agents - chemistry | Chalcone - pharmacology | Chalcone - analogs & derivatives | Anti-Infective Agents - chemistry | Enzyme Inhibitors - chemistry | Antineoplastic Agents - pharmacology
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7. Full Text Synthesis of new chalcone derivatives containing acridinyl moiety with potential antimalarial activity
by Tomar, V and Bhattacharjee, G and Kamaluddin and Rajakumar, S and Srivastava, Kumkum and Puri, S.K
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2010, Volume 45, Issue 2, pp. 745 - 751
A series of novel chalcones bearing acridine moiety attached to the amino group in their ring A have been synthesized through noncatalyzed nucleophilic... 
Plasmodium yoelii N-67 | Acdridne containing chalcones | Plasmodium falciparum NF-54 | ANTIPLASMODIAL ACTIVITY | CHEMISTRY, MEDICINAL | OXYGENATED CHALCONES | FLAVONOIDS | CHLOROQUINE | FERROCENYL CHALCONES | IN-VITRO EVALUATION | PARASITE PLASMODIUM-FALCIPARUM | RESISTANCE | AGENTS | INHIBITORS | Acridines - chemistry | Chalcone - chemistry | Male | Plasmodium - drug effects | Antimalarials - pharmacology | Erythrocytes - drug effects | Animals | Chalcone - pharmacology | Chalcone - analogs & derivatives | Antimalarials - chemistry | Plasmodium - growth & development | Female | Mice | Erythrocytes - parasitology | Chalcone - chemical synthesis | Antimalarials - chemical synthesis | Malaria | Substitution reactions | Plasmodium falciparum
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8. Full Text Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs
by Padhye, Subhash and Ahmad, Aamir and Oswal, Nikhil and Sarkar, Fazlul H
Journal of Hematology and Oncology, ISSN 1756-8722, 2009, Volume 2, Issue 1, pp. 38 - 38
Garcinol, harvested from Garcinia indica, has traditionally been used in tropical regions and appreciated for centuries; however its biological properties are... 
PERFORMANCE LIQUID-CHROMATOGRAPHY | INDUCED GASTRIC-ULCERATION | ONCOLOGY | CANCER CHEMOPREVENTIVE AGENTS | GLOBAL GENE-EXPRESSION | ESI-MS METHOD | ANTIMALARIAL ACTIVITY | CELL-GROWTH | TANDEM MASS-SPECTROMETRY | HEMATOLOGY | ACTIVE POLYISOPRENYLATED BENZOPHENONES | RADICAL REACTION-PRODUCTS | Chalcone - chemistry | Antioxidants - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Antineoplastic Agents - therapeutic use | Chalcones - isolation & purification | Terpenes - pharmacology | Terpenes - chemistry | Chalcone - pharmacology | Chalcone - analogs & derivatives | Chalcones - chemical synthesis | Garcinia - chemistry | Inflammation - drug therapy | Chalcones - pharmacology | Chalcone - therapeutic use | Antineoplastic Agents - pharmacology | Terpenes - isolation & purification | Antioxidants - pharmacology | Neoplasms - drug therapy | Antioxidants - therapeutic use | Animals | Models, Biological | Terpenes - therapeutic use | Chalcones - therapeutic use | HIV Infections - drug therapy | Cellular signal transduction | Research | Health aspects | Benzophenone
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9. Full Text Synthesis and anti-cancer activity evaluation of novel prenylated and geranylated chalcone natural products and their analogs
by Wang, Hao-Meng and Zhang, Li and Zhang, Yong-Min and Liu, Jiang and Yang, Zhao-Liang and Yang, Yao and Zhao, Hong-Ye and Shen, Di and Lu, Kui and Fan, Zhen-Chuan and Yao, Qing-Wei and Teng, Yu-Ou and Peng, Yu
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 92, pp. 439 - 448
Four natural chalcones bearing prenyl or geranyl groups, i.e., bavachalcone ( ), xanthoangelol ( ), isobavachalcone ( ), and isoxanthoangelol ( ) were... 
Prenyled chalcones | Geranylated chalcones | Antitumor agents | K562 cell | Apoptosis | ANGELICA-KEISKEI | CHEMISTRY, MEDICINAL | ANTIBACTERIAL ACTIVITY | XANTHOANGELOL | CHEMICAL-COMPONENTS | ISOBAVACHALCONE | IODINATION | Chalcone - chemistry | Apoptosis - drug effects | Antineoplastic Agents - chemical synthesis | Humans | Endothelium, Vascular - drug effects | Biological Products - pharmacology | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Dose-Response Relationship, Drug | Biological Products - chemical synthesis | Biological Products - chemistry | Chalcone - pharmacology | Chalcone - analogs & derivatives | K562 Cells | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | Chalcone - chemical synthesis | Care and treatment | Synthesis | Safety and security measures | Organic compounds | Food | Cancer | Chemical Sciences
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10. Full Text Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives
by Na, Younghwa and Nam, Jung-Min
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2011, Volume 21, Issue 1, pp. 211 - 214
In order to find potential anticancer drug candidate targeting topoisomerases enzyme, we have designed and synthesized oxiranylmethoxy- and... 
Retrochalcone | Anticancer agents | Thiiranylmethoxy-chalcone | Chalcone | Topoisomerase II | Oxiranylmethoxy-chalcone | Thiiranylmethoxychalcone | CHEMISTRY, MEDICINAL | Oxiranylmethoxychalcone | CHEMISTRY, ORGANIC | RETROCHALCONES | Chalcones - chemistry | DNA Topoisomerases, Type II - metabolism | Chalcone - chemistry | DNA Topoisomerases, Type I - metabolism | Antineoplastic Agents - chemical synthesis | Humans | DNA Topoisomerases, Type I - chemistry | Sulfides - chemistry | Sulfides - chemical synthesis | Topoisomerase II Inhibitors - toxicity | Antineoplastic Agents - chemistry | Antineoplastic Agents - toxicity | Sulfides - toxicity | Chalcones - chemical synthesis | Topoisomerase II Inhibitors - chemistry | Chalcones - toxicity | DNA Topoisomerases, Type II - chemistry | Cell Line, Tumor | Chalcone - toxicity | Topoisomerase II Inhibitors - chemical synthesis | Chalcone - chemical synthesis | Drug Screening Assays, Antitumor | Pharmacy | Antitumor agents
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11. Full Text Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents
by Peng, Fei and Peng, Aihua and Wang, Guangcheng and Li, Xiuxia and Cao, Dong and Yang, Zhuang and Ma, Liang and Ye, Haoyu and Liang, Xiaolin and Ran, Yan and Chen, Jinying and Chen, Lijuan and Qiu, Jingxiang and Xie, Caifeng and Deng, Chongyang and Xiang, Mingli and Wei, Yuquan
European Journal of Medicinal Chemistry, ISSN 0223-5234, 08/2012, Volume 54, pp. 272 - 280
24 derivatives ( – ) derived from natural pyranochalcones ( and ) were designed and evaluated for their inhibitory potency on the production of nitric oxide... 
Adjuvant-induced arthritis | NO production | iNOS | Paw edema | Pyranochalcones | Anti-inflammation | OXIDE SYNTHASE EXPRESSION | ORALLY-ACTIVE GLITAZONE | CHEMISTRY, MEDICINAL | ACUTE LIVER-INJURY | LEAVES | FLAVONOIDS | (Z)-5-(4-METHOXYBENZYLIDENE)THIAZOLIDINE-2,4-DIONE | INHIBITION | CHALCONES | TWIGS | Arthritis, Experimental - drug therapy | Benzopyrans - therapeutic use | Nitric Oxide Synthase Type II - chemistry | Benzopyrans - metabolism | Male | Anti-Inflammatory Agents - metabolism | Chalcones - metabolism | Benzopyrans - chemical synthesis | Chalcone - pharmacology | Chalcones - chemical synthesis | Nitric Oxide Synthase Type II - antagonists & inhibitors | Carrageenan - pharmacology | Chalcones - pharmacology | Drug Design | Anti-Inflammatory Agents - therapeutic use | Chalcone - therapeutic use | Benzopyrans - pharmacology | Cell Line | Catalytic Domain | Chemistry Techniques, Synthetic | Anti-Inflammatory Agents - pharmacology | Edema - drug therapy | Animals | Chalcone - metabolism | Chalcones - therapeutic use | Anti-Inflammatory Agents - chemical synthesis | Mice | Molecular Docking Simulation | Edema - chemically induced | Chalcone - chemical synthesis | Nitric Oxide Synthase Type II - metabolism | Nitrogen oxide | Indomethacin | Anti-inflammatory drugs | Nitric oxide | Analysis
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12. Full Text Synthesis and in vitro antiplasmodial evaluation of 7-chloroquinoline–chalcone and 7-chloroquinoline–ferrocenylchalcone conjugates
by Raj, Raghu and Saini, Anu and Gut, Jiri and Rosenthal, Philip J and Kumar, Vipan
European Journal of Medicinal Chemistry, ISSN 0223-5234, 05/2015, Volume 95, pp. 230 - 239
The manuscript describes the synthesis of novel amide tethered 7-chloroquinoline–chalcone and 7-chloroquinoline–ferrocenylchalcone bifunctional hybrids and... 
7-Chloroquinoline | Ferrocenylchalcone | Antiplasmodial activity | IC50 value | Chalcone | IC | value | DRUG | CHEMISTRY, MEDICINAL | Ferrocbnylchalcone | FERROCENE | DISCOVERY | STRATEGIES | PLASMODIUM-FALCIPARUM | CHALCONES | ANTIMALARIAL ACTIVITY | MALARIA | INHIBITORS | FERROQUINE | Chalcone - chemistry | Chemistry Techniques, Synthetic | Quinones - chemistry | Humans | Antiprotozoal Agents - chemistry | Drug Resistance - drug effects | Plasmodium falciparum - drug effects | Antiprotozoal Agents - pharmacology | Chloroquine - pharmacology | Chalcone - pharmacology | Hydrogen Bonding | Amides - chemistry | Antiprotozoal Agents - chemical synthesis | Chalcone - toxicity | HeLa Cells | Antiprotozoal Agents - toxicity | Chalcone - chemical synthesis
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13. Heterocyclic Chalcone Analogues as Potential Anticancer Agents
by Sharma, V and Kumar, V and Kumar, P
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, ISSN 1871-5206, 03/2013, Volume 13, Issue 3, pp. 422 - 432
Chalcones, aromatic ketones and enones acting as the precursor for flavonoids such as Quercetin, are known for their anticancer effects. Although, parent... 
ANTI-HIV CHALCONE | CHEMISTRY, MEDICINAL | CHEMOPROTECTIVE PROPERTIES | Anticancer agents | HUMAN CANCER-CELLS | P-GLYCOPROTEIN | Heterocyclic chalcone analogues | ANGELICA-KEISKEI | IN-VITRO | ONCOLOGY | BIOLOGICAL EVALUATION | ANTIMALARIAL ACTIVITY | Chalcone analogues | MULTIDRUG-RESISTANCE | ANTIBACTERIAL CHALCONES | Cell Survival - drug effects | Chalcones - chemistry | Chalcones - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Chalcones - pharmacology | Antineoplastic Agents - pharmacology | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Neoplasms - drug therapy
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14. Full Text 1,2,3-Triazole tethered β-lactam-Chalcone bifunctional hybrids: Synthesis and anticancer evaluation
by Singh, Pardeep and Raj, Raghu and Kumar, Vipan and Mahajan, Mohinder P and Bedi, P.M.S and Kaur, Tandeep and Saxena, A.K
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2012, Volume 47, Issue 1, pp. 594 - 600
The manuscript describes the synthesis of novel 1,2,3-triazole tethered -lactam-chalcone bifunctional hybrids click chemistry approach utilizing azide-alkyne... 
Bifunctional hybrids | Triazole | β-Lactam | Anticancer evaluation | Chalcone | CHEMISTRY, MEDICINAL | ANALOGS | CLICK CHEMISTRY | beta-Lactam | DRUG DISCOVERY | INHIBITORY PROPERTIES | ANTIMALARIAL | INVITRO INHIBITORS | DESIGNED MULTIPLE LIGANDS | DERIVATIVES | Chalcone - chemistry | Chalcone - pharmacology | Triazoles - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Cell Line, Tumor | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Antineoplastic Agents - chemistry | Chalcone - chemical synthesis | beta-Lactams - chemistry
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15. Full Text Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity
by Detsi, Anastasia and Majdalani, Maya and Kontogiorgis, Christos A and Hadjipavlou-Litina, Dimitra and Kefalas, Panagiotis
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2009, Volume 17, Issue 23, pp. 8073 - 8085
Naturally occurring and synthetic flavonoids belonging to the 2’hydroxy-chalcone and aurone families, have been synthesized and tested for their antioxidant... 
Lipid peroxidation | Aureusidin | Soybean lipoxygenase | Antioxidant | Aurones | 2′-Hydroxy-chalcones | SUBSTITUTED CHALCONES | OXIDATION | ANTIINFLAMMATORY ACTIVITY | DESIGN | CHEMISTRY, MEDICINAL | RAW-264.7 CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | FLAVONOIDS | 2 '-Hydroxy-chalcones | BIOLOGICAL EVALUATION | AGENTS | 5-LIPOXYGENASE | DERIVATIVES | Chalcones - chemistry | Antioxidants - chemistry | Magnetic Resonance Spectroscopy | Linoleic Acid - metabolism | Picrates - metabolism | Benzofurans - chemical synthesis | Benzofurans - pharmacology | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Biphenyl Compounds - metabolism | Benzofurans - chemistry | Linoleic Acid - antagonists & inhibitors | Lipoxygenase - metabolism | Lipoxygenase Inhibitors - chemical synthesis | Picrates - antagonists & inhibitors | Biphenyl Compounds - antagonists & inhibitors | Chalcones - chemical synthesis | Lipoxygenase Inhibitors - chemistry | Mass Spectrometry | Chalcones - pharmacology | Lipoxygenase Inhibitors - pharmacology
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16. Full Text Anti-tumour activity of a novel coumarin–chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio
by Singh, Neetu and Sarkar, Jayanta and Sashidhara, Koneni V and Ali, Shakir and Sinha, Sudhir
Apoptosis, ISSN 1360-8185, 6/2014, Volume 19, Issue 6, pp. 1017 - 1028
Coumarins and chalcones are secondary plant metabolites which have shown an array of pharmacological properties including anti-tumour activity. We have... 
Biochemistry, general | Biomedicine | Intrinsic pathway | Cancer Research | Oncology | Coumarin | Chalcone | Cell Biology | Virology | Apoptosis | POLY(ADP-RIBOSE) POLYMERASE | GYNECOLOGIC-ONCOLOGY-GROUP | TUMOR SUPPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SQUAMOUS CARCINOMA | CANCER-THERAPY | CELL-DEATH | CELL BIOLOGY | CISPLATIN | BCL-2 PROTEIN FAMILY | X-L | UP-REGULATION | M Phase Cell Cycle Checkpoints | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Uterine Cervical Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Membrane Potential, Mitochondrial - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Chalcone - pharmacology | Heterografts | Chalcone - analogs & derivatives | Chalcones - pharmacology | Apoptosis Regulatory Proteins - genetics | Chalcone - therapeutic use | Female | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins - metabolism | Signal Transduction | Cytochromes c - metabolism | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Uterine Cervical Neoplasms - drug therapy | Mice, SCID | Coumarins - therapeutic use | G2 Phase Cell Cycle Checkpoints | Apoptosis Regulatory Proteins - metabolism | Coumarins - pharmacology | Animals | Cell Line, Tumor | Chalcones - therapeutic use | Cell Proliferation - drug effects | Mice | Cytochrome c | Chemotherapy | Tumor proteins | Plant metabolites | Cervical cancer | Cancer | Tumors
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17. Full Text Synthesis, photophysical and DFT studies of naphthyl chalcone and nicotinonitrile derivatives
by Hegde, Hemant and Sinha, Rajeev K and Kulkarni, Suresh D and Shetty, Nitinkumar S
Journal of Photochemistry and Photobiology A: Chemistry, ISSN 1010-6030, 11/2019, p. 112222
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18. Full Text Metabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting properties
by Eichenberger, Michael and Lehka, Beata Joanna and Folly, Christophe and Fischer, David and Martens, Stefan and Simón, Ernesto and Naesby, Michael
Metabolic Engineering, ISSN 1096-7176, 01/2017, Volume 39, pp. 80 - 89
Dihydrochalcones are plant secondary metabolites comprising molecules of significant commercial interest as antioxidants, antidiabetics, or sweeteners. To... 
Phlorizin | Naringin dihydrochalcone | Dihydrochalcone | Saccharomyces cerevisiae | Nothofagin | Double bond reductase | ESCHERICHIA-COLI | FUNCTIONAL-CHARACTERIZATION | PHLORHIZIN BIOSYNTHESIS | ENOATE REDUCTASE | CHALCONE SYNTHASE | FLAVONOID BIOSYNTHESIS | MALUS X DOMESTICA | ENOYL REDUCTASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MICROBIAL-PRODUCTION | SYNTHETIC BIOLOGY | Metabolic Engineering - methods | Saccharomyces cerevisiae - physiology | Hypoglycemic Agents - metabolism | Sweetening Agents - metabolism | Chalcones - biosynthesis | Hypoglycemic Agents - administration & dosage | Chalcones - administration & dosage | Antioxidants - administration & dosage | Saccharomyces cerevisiae Proteins - metabolism | Metabolic Networks and Pathways - physiology | Genetic Enhancement - methods | Sweetening Agents - administration & dosage | Biosynthetic Pathways - physiology | Antioxidants | Enzymes | Flavonoids | Biological products | Flavones | Bioflavonoids | Physiological aspects | Plant metabolites | Phenylalanine | Cytochrome P-450 | Chemical properties | EMA, European Medicine Agency | VLC, very long chain | CPR, cytochrome P450 reductase | F3H, flavanone 3β-hydroxylase | PAL, phenylalanine ammonia lyase |