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1. Full Text Changes in phytochemical synthesis, chalcone synthase activity and pharmaceutical qualities of sabah snake grass (Clinacanthus nutans L.) in relation to plant age
by Ghasemzadeh, Ali and Nasiri, Alireza and Jaafar, Hawa Z. E and Baghdadi, Ali and Ahmad, Izham
Molecules (Basel, Switzerland), ISSN 1420-3049, 11/2014, Volume 19, Issue 11, pp. 17632 - 17648
FRAP | DPPH | Flavonoid | Sabah snake grass | HeLa cancer | Chalcone synthase | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Free Radical Scavengers - pharmacology | Plant Extracts - chemistry | Antioxidants - chemistry | Free Radical Scavengers - chemistry | Plant Extracts - pharmacology | Humans | Acanthaceae - chemistry | Acyltransferases - pharmacology | Luteolin - chemistry | Poaceae - chemistry | Picrates - chemistry | Hydroxybenzoates - chemistry | Flavonoids - pharmacology | Biphenyl Compounds - chemistry | Gallic Acid - chemistry | Plant Leaves - chemistry | Quercetin - chemistry | Kaempferols - chemistry | Caffeic Acids - chemistry | Antioxidants - pharmacology | Cell Line, Tumor | Phenols - chemistry | Acyltransferases - chemistry | HeLa Cells | Flavonoids - chemistry | Catechin - chemistry | Index Medicus | sabah snake grass | chalcone synthase | flavonoid
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2. Full Text Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds
by Guantai, Eric M and Ncokazi, Kanyile and Egan, Timothy J and Gut, Jiri and Rosenthal, Philip J and Smith, Peter J and Chibale, Kelly
Bioorganic & medicinal chemistry, ISSN 0968-0896, 2010, Volume 18, Issue 23, pp. 8243 - 8256
Plasmodium falciparum | Chalcones | Dienones | Triazole | Malaria | Nucleosides | Hybrid compounds | Aminoquinolines | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Antiparasitic agents | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Chalcones - chemistry | Nucleosides - chemistry | Chalcone - chemistry | Triazoles - chemistry | Quinolines - chemistry | Alkynes - chemistry | Structure-Activity Relationship | Plasmodium falciparum - drug effects | Azides - chemistry | Quinolines - pharmacology | Antimalarials - pharmacology | Hemin - metabolism | Quinolines - chemical synthesis | Animals | Copper - chemistry | Chalcones - chemical synthesis | Aminoquinolines - chemistry | Antimalarials - chemistry | Chalcones - pharmacology | Drug Design | Catalysis | Antimalarials - chemical synthesis | Triazoles | Analysis | Index Medicus
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3. Full Text Chalcone: A Privileged Structure in Medicinal Chemistry
by Zhuang, Chunlin and Zhang, Wen and Sheng, Chunquan and Zhang, Wannian and Xing, Chengguo and Miao, Zhenyuan
Chemical reviews, ISSN 0009-2665, 06/2017, Volume 117, Issue 12, pp. 7762 - 7810
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Biological Products - chemistry | Animals | Chalcone - chemistry | Chalcone - pharmacology | Chemistry, Pharmaceutical - methods | Humans | Biological Products - pharmacology | Molecular Targeted Therapy | Drug Discovery | Biological properties | Target recognition | Organic chemicals | Derivatives | Natural products | Index Medicus
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4. Full Text A Common Pharmacophore for a Diverse Set of Colchicine Site Inhibitors Using a Structure-Based Approach
by Nguyen, Tam Luong and McGrath, Connor and Hermone, Ann R and Burnett, James C and Zaharevitz, Daniel W and Day, Billy W and Wipf, Peter and Hamel, Ernest and Gussio, Rick
Journal of medicinal chemistry, ISSN 0022-2623, 09/2005, Volume 48, Issue 19, pp. 6107 - 6116
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Indans - chemistry | Estradiol - analogs & derivatives | Chalcone - chemistry | Sulfonamides - chemistry | Tubulin Modulators | Aminophenols - chemistry | Lignans - chemistry | Models, Molecular | Stilbenes - chemistry | Structure-Activity Relationship | Nocodazole - chemistry | Cyclopropanes - chemistry | Estradiol - chemistry | Protein Binding | 4-Butyrolactone - chemistry | Thiazoles - chemistry | Molecular Structure | 4-Butyrolactone - analogs & derivatives | Tubulin - chemistry | Podophyllotoxin - chemistry | Binding Sites | Colchicine - chemistry | Index Medicus
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5. Full Text Dynamic Variations in Multiple Bioactive Constituents under Salt Stress Provide Insight into Quality Formation of Licorice
by Wang, Chengcheng and Chen, Lihong and Cai, Zhichen and Chen, Cuihua and Liu, Zixiu and Liu, Xunhong and Zou, Lisi and Chen, Jiali and Tan, Mengxia and Wei, Lifang and Mei, Yuqi
Molecules (Basel, Switzerland), ISSN 1420-3049, 10/2019, Volume 24, Issue 20, p. 3670
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Chalcones - chemistry | Plant Extracts - chemistry | Humans | Drugs, Chinese Herbal - metabolism | Chalcones - metabolism | Tandem Mass Spectrometry | Plant Extracts - metabolism | Triterpenes - chemistry | Flavanones - chemistry | Chromatography, Liquid | Glucosides - chemistry | Salt Stress | Triterpenes - metabolism | Plant Leaves - chemistry | Plant Roots - metabolism | Glycyrrhiza - chemistry | Glycyrrhizic Acid - chemistry | Glycyrrhizic Acid - metabolism | Glucosides - metabolism | Plant Leaves - metabolism | Drugs, Chinese Herbal - chemistry | Flavanones - metabolism | Flavonoids - metabolism | Plant Roots - chemistry | Flavonoids - chemistry | Plant Extracts - therapeutic use | Reductases | Triterpenoids | Superoxide dismutase | Constituents | Synthesis | Pain | Catalase | Metabolites | Peptic ulcers | Glutathione reductase | Quality | Glycosides | Peroxidase | Trends | Glutathione | Enzymes | Antidotes | Abiotic stress | Chemical compounds | Biological activity | Gastritis | Salinity | Organic chemistry | Flavonoids | Acids | Ulcers | Index Medicus | salt stress | licorice | uflc/ms/ms | bioactive constituents
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6. Full Text Nucleophilic Fluoroalkylation of α,β-Enones, Arynes, and Activated Alkynes with Fluorinated Sulfones: Probing the Hard/Soft Nature of Fluorinated Carbanions
by Ni, Chuanfa and Zhang, Laijun and Hu, Jinbo
Journal of organic chemistry, ISSN 0022-3263, 08/2008, Volume 73, Issue 15, pp. 5699 - 5713
Organic chemistry | Chemistry | Preparations and properties | Aliphatic compounds | Exact sciences and technology | Chalcones - chemistry | Cyclohexanones - chemistry | Chlorine Compounds - chemistry | Alkynes - chemistry | Anions - chemistry | Fluorine Compounds - chemistry | Alkylation | Lithium Compounds - chemistry | Acetophenones - chemistry | Sulfones - chemistry | Methane - chemistry | Molecular Structure | Methylation | Index Medicus
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7. Full Text The Health Benefits of Selected Culinary Herbs and Spices Found in the Traditional Mediterranean Diet
by Bower, Allyson and Marquez, Susan and de Mejia, Elvira Gonzalez
Critical reviews in food science and nutrition, ISSN 1040-8398, 12/2016, Volume 56, Issue 16, pp. 2728 - 2746
metabolic syndrome | hyperlipidemia | Diabetes | inflammation | spices | herbs | Food Science & Technology | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Antihypertensive Agents - pharmacology | Flavonoids - analysis | Salvia officinalis - chemistry | Diet, Mediterranean | Anethum graveolens - chemistry | Antihypertensive Agents - analysis | Humans | Thymus Plant - chemistry | Hypoglycemic Agents - analysis | Spices - analysis | Anti-Inflammatory Agents - analysis | Chalcones - analysis | Foeniculum - chemistry | Coriandrum - chemistry | Cuminum - chemistry | Disease Models, Animal | Hydroxybenzoates - analysis | Hypolipidemic Agents - analysis | Petroselinum - chemistry | Plants, Medicinal - chemistry | Artemisia - chemistry | Anti-Inflammatory Agents - pharmacology | Hypolipidemic Agents - pharmacology | Hypoglycemic Agents - pharmacology | Animals | Ocimum basilicum - chemistry | Origanum - chemistry | Laurus - chemistry | Rosmarinus - chemistry | Herbs | Spices | Diet | Metabolic syndrome | Index Medicus
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8. Full Text Individual and combined antiparasitic effect of six plant metabolites against Leishmania amazonensis and Trypanosoma cruzi
by Sandjo, Louis P and de Moraes, Milene H and Kuete, Victor and Kamdoum, Blaise C and Ngadjui, Bonaventure T and Steindel, Mario
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 04/2016, Volume 26, Issue 7, pp. 1772 - 1775
Antiparasitic effect | Secondary metabolites | Activity in combination | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Chalcones - chemistry | Plant Extracts - chemistry | Plant Extracts - pharmacology | Humans | Trypanocidal Agents - chemistry | Structure-Activity Relationship | Flavanones - chemistry | Chalcones - pharmacology | Plants - chemistry | Leishmania mexicana - drug effects | Alkaloids - pharmacology | Flavanones - pharmacology | Zanthoxylum - chemistry | Antiprotozoal Agents - chemistry | Leishmaniasis, Cutaneous - drug therapy | Antiprotozoal Agents - pharmacology | Trypanocidal Agents - pharmacology | Antiparasitic Agents - pharmacology | Chagas Disease - drug therapy | Trypanosoma cruzi - drug effects | Moraceae - chemistry | Anthraquinones - pharmacology | Anthraquinones - chemistry | Alkaloids - chemistry | Antiparasitic Agents - chemistry | Rubiaceae - chemistry | Plant metabolites | Index Medicus
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