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Biochemical Pharmacology, ISSN 0006-2952, 09/2017, Volume 139, pp. 40 - 55
Many chronic human diseases, including multiple neurodegenerative diseases, are associated with deleterious protein aggregates, also called protein amyloids.... 
Covalent mechanisms | Non-covalent mechanisms | Amyloid inhibitor | Natural products | Inhibition mechanisms | CLINICAL-TRIAL | PROTEIN AGGREGATION | ALZHEIMERS-DISEASE | SOLID DISPERSION | TEA POLYPHENOL (-)-EPIGALLOCATECHIN-3-GALLATE | ALPHA-SYNUCLEIN AGGREGATION | BETA-PEPTIDE AGGREGATION | A-BETA | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | AROMATIC-INHIBITOR | Amyloidosis - prevention & control | Drugs, Investigational - pharmacology | Antioxidants - chemistry | Nootropic Agents - metabolism | Antioxidants - metabolism | Healthy Diet | Humans | Polyphenols - pharmacology | Drugs, Investigational - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Biological Products - pharmacology | Flavonoids - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Polyphenols - metabolism | Amyloidogenic Proteins - antagonists & inhibitors | Drugs, Investigational - chemistry | Protein Aggregation, Pathological - prevention & control | Amyloidosis - diet therapy | Drug Design | Flavonoids - pharmacology | Protein Aggregation, Pathological - diet therapy | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Chelating Agents - therapeutic use | Biological Products - therapeutic use | Chelating Agents - chemistry | Nootropic Agents - therapeutic use | Amyloidosis - drug therapy | Antioxidants - pharmacology | Chelating Agents - pharmacology | Nootropic Agents - chemistry | Drug Discovery | Protein Aggregation, Pathological - drug therapy | Amyloidogenic Proteins - metabolism | Antioxidants - therapeutic use | Biological Products - chemistry | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Flavonoids - metabolism | Polyphenols - chemistry | Biological Products - metabolism | Polyphenols - therapeutic use | Chelating Agents - metabolism | Dietary Supplements | Flavonoids - chemistry | Amyloidosis - metabolism | Nootropic Agents - pharmacology | Medicine, Experimental | Medical research | Nervous system diseases | Glycoproteins | Drug discovery | Index Medicus
Journal Article
Journal of Photochemistry & Photobiology, B: Biology, ISSN 1011-1344, 09/2016, Volume 162, pp. 298 - 308
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2/2008, Volume 51, Issue 3, pp. 347 - 372
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2016, Volume 121, pp. 864 - 879
Currently available drugs against Alzheimer's disease (AD) are only able to ameliorate the disease symptoms resulting in a moderate improvement in memory and... 
Human acetylcholinesterase | MAO-A | Molecular modeling | Human butyrylcholinesterase | Metal chelating properties | ADME+T properties | Antioxidant properties | MAO-B | Alzheimer's disease | Molecular docking | CHEMISTRY, MEDICINAL | ALZHEIMERS-DISEASE | CHOLINESTERASE-INHIBITORS | SEROTONIN 5-HT1A | DRUGS | POTENTIAL TREATMENT | NITRIC-OXIDE | FORCE-FIELD | OXIDASE-INHIBITORS | ADME plus T properties | RATIONAL DESIGN | HYBRIDS | Antioxidants - chemistry | Antioxidants - metabolism | Humans | Structure-Activity Relationship | Monoamine Oxidase Inhibitors - chemical synthesis | Monoamine Oxidase - chemistry | Piperidines - pharmacology | Drug Design | Indans - chemistry | Monoamine Oxidase Inhibitors - pharmacology | Piperidines - chemistry | Chemistry Techniques, Synthetic | Piperidines - metabolism | Chelating Agents - chemistry | Indans - metabolism | Acetylcholinesterase - chemistry | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Chelating Agents - pharmacology | Piperidines - chemical synthesis | Monoamine Oxidase Inhibitors - metabolism | Indans - chemical synthesis | Protein Conformation | Molecular Docking Simulation | Monoamine Oxidase Inhibitors - chemistry | Chelating Agents - chemical synthesis | Chelating Agents - metabolism | Acetylcholinesterase - metabolism | Indans - pharmacology | Monoamine Oxidase - metabolism | Antioxidants | Enzymes | Monoamine oxidase | Analysis | Models | Drug discovery | Target marketing
Journal Article
Environmental Science and Pollution Research, ISSN 0944-1344, 3/2016, Volume 23, Issue 5, pp. 3984 - 3999
Journal Article
Cellular and Molecular Biology, ISSN 0145-5680, 2007, Volume 53, Issue 1, pp. 15 - 25
Phenylpropanoids (PPs) belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as... 
Antioxidants | Phytoestrogens | UV-screen | Phenylpropanoids | Anti-cancer | Metabolism | Plant defense | Anti-inflammatory | Cytoprotective action | and cytoprotective action | antioxidants | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENYLETHANOID GLYCOSIDES | ACID PHENETHYL ESTER | phytoestrogens | anti-cancer | S-PHASE ARREST | ESTROGEN-RECEPTOR | CELL BIOLOGY | BREAST-CANCER CELLS | IN-VITRO | plant defense | CAFFEIC ACID | anti-inflammatory | metabolism | P-METHOXYCINNAMIC ACID | NF-KAPPA-B | phenylpropanoids | Plant Extracts - chemistry | Reactive Oxygen Species - metabolism | Antioxidants - chemistry | Oxidative Stress | Free Radical Scavengers - chemistry | Antioxidants - metabolism | Humans | Antineoplastic Agents - therapeutic use | Anti-Inflammatory Agents - metabolism | Antineoplastic Agents - metabolism | Plant Extracts - metabolism | Free Radical Scavengers - therapeutic use | Plants - chemistry | Estrogens - metabolism | Biological Products - therapeutic use | Cytoprotection | Free Radical Scavengers - metabolism | Phenols - metabolism | Antineoplastic Agents - chemistry | Antioxidants - therapeutic use | Biological Products - chemistry | Plants - metabolism | Animals | Anti-Inflammatory Agents - chemistry | Phenols - therapeutic use | Biological Products - metabolism | Cell Line, Tumor | Phenols - chemistry | Estrogen Receptor Modulators - metabolism | Chelating Agents - metabolism | Plant Extracts - therapeutic use
Journal Article
Science, ISSN 0036-8075, 2/2008, Volume 319, Issue 5865, pp. 962 - 965
Bacterial infection often results in the formation of tissue abscesses, which represent the primary site of interaction between invading bacteria and the... 
Microbial growth | Kidneys | Antimicrobials | Liver | Abscesses | Neutrophils | Chelation | Reports | Mice | Infections | Staphylococcus | CALPROTECTIN | STAPHYLOCOCCUS-AUREUS | EXPRESSION | MULTIDISCIPLINARY SCIENCES | EF-HAND PROTEINS | ANTIMICROBIAL ACTIVITY | Abscess - microbiology | Abscess - metabolism | Calcium - metabolism | Zinc - metabolism | Leukocyte L1 Antigen Complex - metabolism | Gene Expression Profiling | Liver Abscess - metabolism | Liver Abscess - microbiology | Mass Spectrometry | Leukocyte L1 Antigen Complex - pharmacology | Staphylococcal Infections - microbiology | Dimerization | Neutrophils - metabolism | Kidney Diseases - metabolism | Staphylococcal Infections - metabolism | Staphylococcus aureus - genetics | Kidney Diseases - microbiology | Liver Abscess - pathology | Staphylococcal Infections - immunology | Chelating Agents - pharmacology | Kidney Diseases - immunology | Animals | Manganese - metabolism | Leukocyte L1 Antigen Complex - genetics | Abscess - immunology | Chelating Agents - metabolism | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Bacterial growth | Control | Care and treatment | Immune response | Bacterial infections | Abscess | Research | Chelation therapy | Methods | Bacteria | Staphylococcus infections | Biomedical research | Immunology | Metals | Rodents
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2013, Volume 169, Issue 3, pp. 296 - 305
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2010, Volume 16, Issue 27, pp. 2950 - 2960
Bisphosphonates are widely used in the treatment of diseases involving excessive bone resorption, such as osteoporosis, cancer-associated bone disease, and... 
Bisphosphonate | Fpp synthase | Monocyte | Bone affinity | Protein prenylation | Osteoclast | Osteocyte | Macrophage | GROWTH-INHIBITION | protein prenylation | NITROGEN-CONTAINING BISPHOSPHONATES | macrophage | DELTA T-CELLS | osteocyte | GTP-BINDING PROTEINS | FUNCTION IN-VITRO | OSTEOCLAST PRECURSORS | ZOLEDRONIC ACID | ACUTE-PHASE RESPONSE | bone affinity | monocyte | TUMOR-ASSOCIATED MACROPHAGES | PHARMACOLOGY & PHARMACY | FPP synthase | osteoclast | POSTMENOPAUSAL WOMEN | Calcium - metabolism | Humans | Monocytes - metabolism | Bone and Bones - drug effects | Tissue Distribution | Chelating Agents - pharmacokinetics | Bone and Bones - metabolism | Drug Design | Diphosphonates - therapeutic use | Bone Density Conservation Agents - metabolism | Chelating Agents - therapeutic use | Bone Density Conservation Agents - pharmacokinetics | Bone Resorption - drug therapy | Bone Density Conservation Agents - therapeutic use | Diphosphonates - pharmacokinetics | Diphosphonates - metabolism | Chelating Agents - pharmacology | Organ Specificity | Bone Density Conservation Agents - pharmacology | Monocytes - drug effects | Macrophages - metabolism | Animals | Macrophages - drug effects | Chelating Agents - metabolism | Diphosphonates - pharmacology | Drugs | Enzymes | Animal models | Cytotoxicity | Osteocytes | Bone diseases | Minerals | Macrophages | Bisphosphonates | Survival | Clodronic acid | Bone resorption | Paget's disease | Monocytes | Osteoclasts | Skeleton | ATP | Apoptosis | Guanosinetriphosphatase
Journal Article
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 09/2011, Volume 91, Issue 12, pp. 2284 - 2291