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61. Bisphosphonates: Molecular mechanisms of action and effects on bone cells, monocytes and macrophages
by Roelofs, A.J and Thompson, K and Ebetino, F.H and Rogers, M.J and Coxon, F.P
Current pharmaceutical design, ISSN 1381-6128, 2010, Volume 16, Issue 27, pp. 2950 - 2960
Bisphosphonate | Fpp synthase | Monocyte | Bone affinity | Protein prenylation | Osteoclast | Osteocyte | Macrophage | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Calcium - metabolism | Humans | Monocytes - metabolism | Bone and Bones - drug effects | Tissue Distribution | Chelating Agents - pharmacokinetics | Bone and Bones - metabolism | Drug Design | Diphosphonates - therapeutic use | Bone Density Conservation Agents - metabolism | Chelating Agents - therapeutic use | Bone Density Conservation Agents - pharmacokinetics | Bone Resorption - drug therapy | Bone Density Conservation Agents - therapeutic use | Diphosphonates - pharmacokinetics | Diphosphonates - metabolism | Chelating Agents - pharmacology | Organ Specificity | Bone Density Conservation Agents - pharmacology | Monocytes - drug effects | Macrophages - metabolism | Animals | Macrophages - drug effects | Chelating Agents - metabolism | Diphosphonates - pharmacology | Drugs | Enzymes | Animal models | Cytotoxicity | Osteocytes | Bone diseases | Minerals | Macrophages | Bisphosphonates | Survival | Clodronic acid | Bone resorption | Paget's disease | Monocytes | Osteoclasts | Skeleton | ATP | Apoptosis | Guanosinetriphosphatase
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62. Tacrine-based multifunctional agents in Alzheimer's disease: an old story in continuous development
by Milelli, Andrea and De Simone, Angela and Ticchi, Nicole and Chen, Huan Huan and Betari, Nibal and Andrisano, Vincenza and Tumiatti, Vincenzo
Current medicinal chemistry, ISSN 0929-8673, 2017, Volume 24, Issue 32, pp. 1 - 25
Acetylcholinesterase inhibitors | Dual binding acetylcholinesterase inhibitors | Neurodegenerative diseases | Alzheimer's Disease | Tacrine hybrids | Tacrine | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Reactive Oxygen Species - metabolism | Humans | Chelating Agents - chemistry | Cholinesterase Inhibitors - chemistry | Alzheimer Disease - drug therapy | Alzheimer Disease - enzymology | Chelating Agents - pharmacology | Drug Discovery | Tacrine - therapeutic use | Tacrine - pharmacology | Animals | Cholinesterase Inhibitors - pharmacology | Butyrylcholinesterase - metabolism | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Ligands | Cholinesterase Inhibitors - therapeutic use | Tacrine - analogs & derivatives | Chelating Agents - therapeutic use | Acetylcholinesterase - metabolism | Reactive oxygen species | Acetylcholinesterase | Cholinesterase | Blockage | Literature reviews | Reviews | Chelation | β-Amyloid | Alzheimers disease | Alzheimer's disease | Secretase | Bibliographic data bases
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63. Full Text Deferasirox for managing iron overload in people with thalassaemia
by Bollig, Claudia and Schell, Lisa K and RĂĽcker, Gerta and Allert, Roman and Motschall, Edith and Niemeyer, Charlotte M and Bassler, Dirk and Meerpohl, Joerg J and Meerpohl, Joerg J
Cochrane library, ISSN 1469-493X, 08/2017, Volume 2017, Issue 8, pp. CD007476 - CD007476
HAEMOGLOBINOPATHIES | TREATMENT | Deferiprone | Deferoxamine | Patient Satisfaction | Clinical Trials, Phase III as Topic | Triazoles | Child health | BLOOD | Benzoates | Genetic disorders | THALASSAEMIA | Administration, Oral | Erythrocyte Transfusion | Pyridones | Thalassemia | IRON CHELATION | Randomized Controlled Trials as Topic | Deferasirox | Blood disorders | Iron Chelating Agents | Medicine General & Introductory Medical Sciences | Ferritins | Clinical Trials, Phase II as Topic | Iron Overload | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Index Medicus
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64. Full Text Therapy induced iron deficiency in children treated with eltrombopag for immune thrombocytopenia
by Lambert, Michele P and Witmer, Char M and Kwiatkowski, Janet L
American journal of hematology, ISSN 0361-8609, 06/2017, Volume 92, Issue 6, pp. E88 - E91
Life Sciences & Biomedicine | Hematology | Science & Technology | Benzoates - adverse effects | Pyrazoles - therapeutic use | Benzoates - therapeutic use | Benzoates - chemistry | Humans | Recombinant Fusion Proteins - therapeutic use | Male | Thrombopoietin - therapeutic use | Anemia, Iron-Deficiency - blood | Iron Chelating Agents - chemistry | Purpura, Thrombocytopenic, Idiopathic - drug therapy | Receptors, Fc - therapeutic use | Young Adult | Hydrazines - chemistry | Pyrazoles - chemistry | Ferritins - blood | Female | Molecular Structure | Drug Therapy, Combination | Pyrazoles - adverse effects | Hydrazines - therapeutic use | Iron Chelating Agents - therapeutic use | Iron - metabolism | Anemia, Iron-Deficiency - chemically induced | Iron Chelating Agents - adverse effects | Platelet Count | Adolescent | Hydrazines - adverse effects | Thrombocytopenia | Idiopathic thrombocytopenic purpura | Nutrient deficiency | Index Medicus
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65. Full Text Inhibitory effect of Nymphaea pubescens Willd. flower extract on carrageenan-induced inflammation and CCl4-induced hepatotoxicity in rats
by Debnath, Sukalyani and Ghosh, Subhalakshmi and Hazra, Banasri
Food and chemical toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 485 - 491
CCl4-induced hepatotoxicity | Free radical scavenger | iNOS | Anti-inflammatory | Nymphaea pubescens | Carrageenan-induced paw edema | INOS | Food Science & Technology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Phenols - isolation & purification | Flowers - chemistry | Carbon Tetrachloride Poisoning - prevention & control | Dietary Supplements - analysis | Liver - immunology | Plant Extracts - metabolism | Liver - drug effects | Saponins - therapeutic use | Free Radical Scavengers - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Chelating Agents - therapeutic use | Subcutaneous Tissue - metabolism | Edema - prevention & control | Liver - metabolism | Rats | Plant Extracts - isolation & purification | Random Allocation | Free Radical Scavengers - isolation & purification | India | Edema - metabolism | Carbon Tetrachloride Poisoning - blood | Ethnopharmacology | Macrophages - metabolism | Saponins - isolation & purification | Chelating Agents - isolation & purification | Subcutaneous Tissue - immunology | Flavonoids - isolation & purification | Mice | Saponins - metabolism | Plant Extracts - therapeutic use | Saponins - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - isolation & purification | Flavonoids - therapeutic use | Plant Extracts - administration & dosage | Carbon Tetrachloride Poisoning - metabolism | Flavonoids - administration & dosage | Nymphaea - chemistry | Macrophages - immunology | Edema - immunology | Free Radical Scavengers - metabolism | Cells, Cultured | Free Radical Scavengers - administration & dosage | Macrophages - cytology | Phenols - metabolism | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Flavonoids - metabolism | Phenols - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Carbon Tetrachloride Poisoning - immunology | Phenols - administration & dosage | Chelating Agents - metabolism | Index Medicus
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66. Full Text How I treat transfusional iron overload
by Hoffbrand, A. Victor and Taher, Ali and Cappellini, Maria Domenica
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 18, pp. 3657 - 3669
Life Sciences & Biomedicine | Hematology | Science & Technology | Deferasirox | Iron Overload - etiology | Iron Chelating Agents - therapeutic use | Benzoates - therapeutic use | Iron Overload - drug therapy | Humans | Deferoxamine - therapeutic use | Deferiprone | Pyridones - therapeutic use | Hematologic Diseases - therapy | Transfusion Reaction | Triazoles - therapeutic use
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67. Full Text Therapeutic Potential of Copper Chelation with Triethylenetetramine in Managing Diabetes Mellitus and Alzheimer’s Disease
by Cooper, Garth J. S
Drugs (New York, N.Y.), ISSN 0012-6667, 7/2011, Volume 71, Issue 10, pp. 1281 - 1320
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | diabetic arteriopathy | heart failure | selective copper chelation | diabetic neuropathy | diabetic retinopathy | organ regeneration | arteriosclerosis | Copper overload | triethylenetetramine | experimental therapeutics | iron | randomized clinical trials | Alzheimers disease | diabetes | experimental pharmacology | zinc | diabetic nephropathy | oxidative stress | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Neurology | Organic mental disorders. Neuropsychology | Diabetes. Impaired glucose tolerance | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Psychopathology. Psychiatry | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Alzheimer Disease - physiopathology | Diabetes Complications - physiopathology | Humans | Diabetes Mellitus - drug therapy | Alzheimer Disease - drug therapy | Diabetes Complications - drug therapy | Chelating Agents - pharmacology | Trientine - pharmacology | Drug Delivery Systems | Trientine - therapeutic use | Animals | Diabetes Mellitus - physiopathology | Copper - metabolism | Chelating Agents - therapeutic use | Research | Diabetes | Drug therapy | Polyamines | Alzheimer's disease | Health aspects | Index Medicus
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