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2013, 3, ISBN 9780123878175, 771
... to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much... 
Drugs | Side effects | Effect of drugs on | Hepatotoxicology | Liver
eBook
1996, Handbook of experimental pharmacology, ISBN 3540602011, Volume 121., xxxi, 681
Book
Drug safety, ISSN 0114-5916, 2007, Volume 30, Issue 4, pp. 277 - 294
Journal Article
Journal Article
The Journal of pathology, ISSN 1096-9896, 12/2018, Volume 247, Issue 1, pp. 110 - 122
Ibuprofen is a worldwide used non‐steroidal anti‐inflammatory drug which may cause acute liver injury (ALI... 
toxicity | POPULATION | JNK | MEDIATOR | ibuprofen | liver failure | NECROSIS | HEPATITIS | RESPIRATION | drug-induced liver injury (DILI) | HEPATOTOXICITY | OUTCOMES | VANISHING BILE-DUCT | STEVENS-JOHNSON-SYNDROME | drug‐induced liver injury (DILI) | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Liver - pathology | Phosphorylation | Liver - enzymology | Humans | Liver Failure, Acute - enzymology | Hepatocytes - pathology | Male | Mitogen-Activated Protein Kinase 9 - genetics | Liver Failure, Acute - genetics | Cell Death | Ibuprofen | Mitogen-Activated Protein Kinase 8 - genetics | Liver Failure, Acute - prevention & control | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - enzymology | Disease Models, Animal | Chemical and Drug Induced Liver Injury - prevention & control | Signal Transduction | Mitogen-Activated Protein Kinase 9 - metabolism | Mice, Inbred C57BL | Mitogen-Activated Protein Kinase 8 - metabolism | Chemical and Drug Induced Liver Injury - genetics | Mitogen-Activated Protein Kinase 9 - deficiency | Mice, Knockout | Animals | Liver Failure, Acute - pathology | Enzyme Activation | Hepatocytes - enzymology | Enzymes | Liver diseases | Analysis | Liver | Transplantation of organs, tissues, etc | Histochemistry | Animal models | Protein kinase C | Syngeneic grafts | Toxicity | Cytotoxicity | AKT protein | Activation | Transplantation | Histopathology | Allografts | Pathways | Clonal deletion | Rodents | Animal tissues | Biocompatibility | Nonsteroidal anti-inflammatory drugs | Injuries | MAP kinase | Histology | Inflammation | siRNA | Investigations | Hepatocytes | Transaminases | Mice | Intoxication | Cytoplasm | Liver transplantation | Biochemical markers | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 01/2013, Volume 110, Issue 6, pp. 2324 - 2329
In many organs, myofibroblasts play a major role in the scarring process in response to injury... 
Phenotypes | Hepatocytes | Epithelial cells | Liver | Fibrosis | Cell lines | Antibodies | Hepatic stellate cells | Myofibroblasts | Liver cells | Epithelial-mesenchymal transition | Alpha-smooth muscle actin | Glisson's capsule | Podoplanin | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Liver - pathology | WT1 Proteins - metabolism | Membrane Glycoproteins - metabolism | Hepatic Stellate Cells - metabolism | RNA, Messenger - metabolism | Liver - injuries | Myofibroblasts - metabolism | Biliary Tract - metabolism | Cell Transdifferentiation - drug effects | Liver Cirrhosis - metabolism | Chemical and Drug Induced Liver Injury - pathology | WT1 Proteins - genetics | Hepatic Stellate Cells - pathology | Liver Cirrhosis - etiology | Myofibroblasts - pathology | Epithelium - pathology | Gene Expression | Liver Regeneration | Epithelium - metabolism | Signal Transduction | Liver - metabolism | RNA, Messenger - genetics | Cells, Cultured | Mice, Transgenic | Chemical and Drug Induced Liver Injury - genetics | Carbon Tetrachloride - toxicity | Biliary Tract - pathology | Nerve Tissue Proteins - metabolism | Cell Lineage | Transforming Growth Factor beta - pharmacology | Animals | Chemical and Drug Induced Liver Injury - metabolism | Liver Cirrhosis - pathology | Mesoderm - metabolism | Mice | Mesoderm - pathology | Transforming Growth Factor beta - metabolism | Glycoproteins | Liver diseases | Rodents | Cells | Tumors | Index Medicus | alpha-smooth muscle actin | Biological Sciences | fibrosis | podoplanin
Journal Article
American journal of physiology: Gastrointestinal and liver physiology, ISSN 1522-1547, 07/2012, Volume 303, Issue 1, pp. G32 - G41
.... We examined the effects of Lactobacillus rhamnosus GG culture supernatant (LGG-s) on the acute alcohol-induced intestinal integrity and liver injury in a mouse model... 
Gut permeability | Hypoxia-inducible factor | Alcoholic liver disease | Gastroenterology & Hepatology | Physiology | Life Sciences & Biomedicine | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Liver - pathology | Reactive Oxygen Species - metabolism | Ethanol - toxicity | Ileum - metabolism | Male | Hypoxia-Inducible Factor 1 - metabolism | Intestinal Mucosa - drug effects | Ileum - drug effects | Ethanol - blood | Basic Helix-Loop-Helix Transcription Factors - metabolism | Chemical and Drug Induced Liver Injury - pathology | Culture Media - chemistry | Central Nervous System Depressants - toxicity | Real-Time Polymerase Chain Reaction | Chemical and Drug Induced Liver Injury - enzymology | Tight Junctions - drug effects | Liver Diseases, Alcoholic - pathology | Liver Function Tests | Chemical and Drug Induced Liver Injury - prevention & control | Permeability - drug effects | Central Nervous System Depressants - antagonists & inhibitors | Liver - metabolism | Mice, Inbred C57BL | Liver Diseases, Alcoholic - prevention & control | Triglycerides - metabolism | Animals | Lactobacillus rhamnosus - metabolism | Mice | Central Nervous System Depressants - blood | Ethanol - antagonists & inhibitors | Peroxidase - metabolism | Colorectal diseases | Care and treatment | Diagnosis | Health aspects | Gastrointestinal diseases | Lactobacillus | Index Medicus | alcoholic liver disease | hypoxia-inducible factor | gut permeability | Liver and Biliary Tract
Journal Article
PloS one, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0176106 - e0176106
...) and the animals were subjected to lipopolysaccharide (LPS)/Galactosamine (GalN)-induced acute liver inflammation and injury... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Liver - pathology | Humans | Lipopolysaccharides - administration & dosage | Tumor Necrosis Factor-alpha - genetics | Culture Media, Conditioned - pharmacology | Hepatocytes - metabolism | PPAR gamma - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Hepatocytes - cytology | Liver - drug effects | Kupffer Cells - metabolism | Chemical and Drug Induced Liver Injury - pathology | Transgenes | Hepatocytes - drug effects | PPAR gamma - genetics | Chemical and Drug Induced Liver Injury - prevention & control | Dinoprostone - pharmacology | Kupffer Cells - cytology | Macrophages - pathology | Paracrine Communication | Signal Transduction | Liver - metabolism | Gene Expression Regulation | Mice, Transgenic | Chemical and Drug Induced Liver Injury - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Aspartate Aminotransferases - metabolism | Kupffer Cells - drug effects | Dinoprostone - metabolism | Macrophages - metabolism | Animals | PPAR gamma - antagonists & inhibitors | Chemical and Drug Induced Liver Injury - metabolism | Anilides - pharmacology | Dinoprostone - analogs & derivatives | Macrophages - drug effects | Mice | Alanine Transaminase - metabolism | Primary Cell Culture | Macrophage Activation - drug effects | Prevention | Care and treatment | Liver diseases | Physiological aspects | Genetic aspects | Research | Oxidoreductases | Gene expression | Medical research | Dehydrogenases | Cytokines | Tissue engineering | Laboratories | Inflammation | Macrophages | Medicine | Liver cancer | Pathology | Hepatitis | Immunology | Transgenic animals | Rodents | Ligands | Oxidation | Apoptosis | Index Medicus
Journal Article