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Journal of Controlled Release, ISSN 0168-3659, 2011, Volume 152, Issue 2, pp. 232 - 240
A strategy has been designed to develop hyaluronic acid (HA) hydrogel for bone augmentation using minimal invasive technique. A mild synthetic procedure was... 
In vivo | Bone tissue engineering | Hydrogel | Hyaluronic acid | BMP (bone morphogenetic protein) | Controlled release | CELLS | FUSION | RECONSTRUCTION | REGENERATION | STRATEGY | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | RHBMP-2 | PHARMACOLOGY & PHARMACY | DIFFERENTIATION | SCAFFOLDS | MORPHOGENETIC PROTEIN-2 | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Humans | Delayed-Action Preparations - chemistry | Male | Delayed-Action Preparations - administration & dosage | Bone Morphogenetic Protein 2 - administration & dosage | Hydrogel, Polyethylene Glycol Dimethacrylate - administration & dosage | Skull - drug effects | Hydrogel, Polyethylene Glycol Dimethacrylate - metabolism | Cell Line | Hyaluronic Acid - administration & dosage | Cross-Linking Reagents - chemistry | Cell Survival | Osteogenesis - drug effects | Hyaluronic Acid - chemistry | Hydrazones - administration & dosage | Rats | Hydrazones - metabolism | Rats, Sprague-Dawley | Hydrazones - chemistry | Delayed-Action Preparations - metabolism | Injections | Animals | Hyaluronic Acid - metabolism | Skull - ultrastructure | Aldehydes - chemistry | Osteocalcin | Bone morphogenetic protein 2 | Osteopontin | Cytotoxicity | hydrogels | Aldehydes | pH effects | Angiogenesis | Orthopedics | Bone marrow | Oxidation | Osteogenesis | Medical and Health Sciences | Polymer Chemistry | Medicin och hälsovetenskap | Klinisk medicin | MEDICINE | Chemical Sciences | Kemi med inriktning mot polymerkemi | Polymerkemi | Surgery | Chemistry with specialization in Polymer Chemistry | Natural Sciences | Kirurgi | Clinical Medicine | Organic chemistry | Chemistry | Naturvetenskap | Kemi | MEDICIN | Organisk kemi
Journal Article
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2012, Volume 162, Issue 3, pp. 646 - 653
Understanding the influence of formulation and storage conditions on rhBMP-2 bioactivity is extremely important for its clinical application. Reports in the... 
Bone morphogenetic protein-2 | Protein stability | Hydrogel | Hyaluronic acid | Tissue engineering | CELLS | HYDROGELS | GRAFTS | REGENERATION | HYALURONAN | BMP-2 | CHEMISTRY, MULTIDISCIPLINARY | PHARMACOLOGY & PHARMACY | MORPHOGENETIC PROTEIN-2 | NIH 3T3 Cells | Alkaline Phosphatase - metabolism | Drug Carriers - administration & dosage | Bone Morphogenetic Protein 2 - chemistry | Male | Transforming Growth Factor beta - chemistry | Drug Carriers - chemistry | Hydrazines - chemistry | Bone Morphogenetic Protein 2 - administration & dosage | Hydrogels - administration & dosage | Cell Line | Cell Survival - drug effects | Rheology | Drug Stability | Osteogenesis - drug effects | Hyaluronic Acid - chemistry | Rats | Recombinant Proteins - chemistry | Rats, Sprague-Dawley | Recombinant Proteins - administration & dosage | Collagen - metabolism | Animals | Transforming Growth Factor beta - administration & dosage | Cell Proliferation - drug effects | Mice | Hydrogels - chemistry | Aldehydes - chemistry | Hydrogen-Ion Concentration | Animal experimentation | Analysis | Collagen | Physiological aspects | Bone morphogenetic proteins | Organic chemistry | Polymerkemi | Chemistry | Naturvetenskap | Polymer Chemistry | Kemi | Chemistry with specialization in Polymer Chemistry | Natural Sciences | Organisk kemi | Chemical Sciences | Kemi med inriktning mot polymerkemi
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 2011, Volume 7, Issue 8, pp. 3042 - 3049
Current treatment of fractures often involves the use of bone graft or bone morphogenetic proteins (BMP) to induce fracture healing, especially in patients... 
Injectable | In vivo | Hydrogel | Nanosized | Calcium phosphates | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | PROLIFERATION | OSTEOGENESIS | TRICALCIUM PHOSPHATE | HYDROXYAPATITE | HYALURONIC-ACID | IN-VITRO | CELL-SURFACE RECEPTOR | OSTEOBLASTS | DIFFERENTIATION | PRECURSORS | Bone Morphogenetic Protein 2 - pharmacology | Nanostructures - ultrastructure | Femur - pathology | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Choristoma - diagnostic imaging | Muscles - diagnostic imaging | Humans | Osteogenesis - drug effects | Rats | Calcium Phosphates - chemistry | Durapatite - chemistry | Femur - drug effects | Male | Tomography, X-Ray Computed | Femur - diagnostic imaging | Rats, Sprague-Dawley | Drug Carriers - chemistry | Animals | Muscles - drug effects | Choristoma - pathology | Minerals - metabolism | Biological products | Fractures | Biomimetics | Hydroxylapatite | Bones | Calcium phosphate | Bone morphogenetic proteins | Density | Engineering Science with specialization in Materials Science | Medical and Health Sciences | Polymer Chemistry | Teknisk fysik med inriktning mot materialvetenskap | Medicin och hälsovetenskap | Teknik och teknologier | MEDICINE | Chemical Sciences | Kemi med inriktning mot polymerkemi | Organic chemistry | Polymerkemi | Engineering and Technology | Chemistry | Naturvetenskap | Kemi | MEDICIN | Chemistry with specialization in Polymer Chemistry | Natural Sciences | Organisk kemi
Journal Article