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Nature (London), ISSN 1476-4687, 2016, Volume 532, Issue 7598, pp. 245 - 249
Journal Article
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2012, Volume 55, Issue 3, pp. 807 - 820
A novel theory in the field of tumor biology postulates that cancer growth is driven by a population of stem‐like cells, called tumor‐initiating cells (TICs).... 
HEPATOCELLULAR-CARCINOMA CELLS | NEUROTENSIN | STEM-CELLS | CANCER STEM/PROGENITOR CELLS | PROGNOSIS | HUMAN LIVER-CANCER | IDENTIFICATION | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | INTERLEUKIN-8 PRODUCTION | CD133 | Interleukin-8 - genetics | Liver - pathology | Cell Proliferation | Humans | Glycoproteins - metabolism | Peptides - genetics | Neoplastic Stem Cells - immunology | Interleukin-8 - physiology | Peptides - deficiency | Antigens, CD - genetics | Antigens, CD - metabolism | Hepatectomy | Mitogen-Activated Protein Kinase Kinases | Peptides - metabolism | Chemokine CXCL1 - physiology | Neurotensin - pharmacology | Carcinoma, Hepatocellular - blood supply | Glycoproteins - deficiency | Liver Neoplasms - pathology | Neovascularization, Pathologic - physiopathology | Liver - surgery | Neoplastic Stem Cells - physiology | Glycoproteins - genetics | Interleukin-8 - deficiency | Cells, Cultured | Carcinoma, Hepatocellular - surgery | Liver Neoplasms - surgery | AC133 Antigen | Neurotensin - physiology | Xenograft Model Antitumor Assays | Feedback, Physiological | Liver - blood supply | Animals | Liver Neoplasms - blood supply | Mice, Nude | Carcinoma, Hepatocellular - pathology | Cell Line, Tumor | Signal Transduction - physiology | Mice | Angiogenesis | Tumorigenesis | Cytokines | Kinases | Gene expression
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 05/2014, Volume 306, Issue 9, pp. E1077 - E1084
Journal Article
Journal Article
Nature immunology, ISSN 1529-2916, 2011, Volume 12, Issue 9, pp. 853 - 860
.... We show here that IL-17 enhanced the stability of chemokine CXCL1 mRNA and other mRNAs through a pathway that involved the adaptor Act1, the adaptors TRAF2 or TRAF5 and the splicing factor SF2... 
ACTIVATED PROTEIN-KINASE | NEUTROPHIL INFILTRATION | FACTOR ASF/SF2 | STABILIZATION | STABILITY | FUNCTIONAL-ANALYSIS | GENE-EXPRESSION | RECEPTOR | IMMUNOLOGY | NF-KAPPA-B | POSTTRANSCRIPTIONAL CONTROL | RNA-Binding Proteins - genetics | Alternative Splicing | Humans | Interleukin-17 - immunology | Half-Life | TNF Receptor-Associated Factor 5 - immunology | Chemokine CXCL1 - genetics | Interleukin-17 - pharmacology | RNA Stability - drug effects | Signal Transduction - immunology | Inflammation - metabolism | Th17 Cells - metabolism | Adaptor Proteins, Signal Transducing - immunology | Female | Transcription, Genetic | Chemokine CXCL1 - metabolism | Nuclear Proteins - genetics | RNA Processing, Post-Transcriptional | RNA-Binding Proteins - immunology | Nuclear Proteins - metabolism | Inflammation - immunology | TNF Receptor-Associated Factor 5 - metabolism | Nuclear Proteins - immunology | Mice, Knockout | Chemokine CXCL1 - immunology | Interleukin-17 - metabolism | TNF Receptor-Associated Factor 5 - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | Serine-Arginine Splicing Factors | Inflammation - genetics | Th17 Cells - immunology | Mice | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | RNA, Messenger | RNA-Binding Proteins - metabolism | Physiological aspects | Messenger RNA | Research | Interleukins | Health aspects | Chemokines
Journal Article
Mucosal immunology, ISSN 1935-3456, 2015, Volume 9, Issue 2, pp. 503 - 514
We used an extracellular pathogen Klebsiella pneumoniae to determine the role of NLRP12 (NOD-like receptor (NLR) family pyrin domain containing 12) as this... 
LUNG | ACTIVATION | HISTONE DEACETYLASES | COLON INFLAMMATION | CYTOKINE | BACTERIAL-INFECTION | T-CELL | IMMUNOLOGY | NF-KAPPA-B | KLEBSIELLA-PNEUMONIAE | NEUTROPHIL ACCUMULATION | Lung - microbiology | Macrophages - transplantation | Bone Marrow - immunology | Klebsiella Infections - pathology | Humans | Interleukin-17 - immunology | Pneumonia - pathology | Intracellular Signaling Peptides and Proteins - immunology | Chemokine CXCL1 - genetics | CD4-Positive T-Lymphocytes - pathology | Neutrophil Infiltration | CD4-Positive T-Lymphocytes - immunology | Intracellular Signaling Peptides and Proteins - deficiency | Pneumonia - immunology | Female | Neutrophils - microbiology | Intracellular Signaling Peptides and Proteins - genetics | Macrophages - immunology | Macrophages - microbiology | Neutrophils - pathology | Pneumonia - genetics | Lung - pathology | CD4-Positive T-Lymphocytes - microbiology | Klebsiella pneumoniae - immunology | Macrophages - pathology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Neutrophils - immunology | Interleukin-17 - genetics | Epithelial Cells - pathology | Klebsiella Infections - genetics | Pneumonia - microbiology | Klebsiella Infections - microbiology | Transplantation Chimera | Mice, Knockout | Chemokine CXCL1 - immunology | Animals | CD4-Positive T-Lymphocytes - transplantation | Klebsiella Infections - immunology | Bone Marrow - pathology | Epithelial Cells - immunology | Epithelial Cells - microbiology | Mice | Bone Marrow - microbiology | Lung - immunology
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2009, Volume 158, Issue 3, pp. 779 - 789
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 07/2015, Volume 309, Issue 1, pp. G30 - G41
.... Induction of neutrophil-recruiting chemokines, including Cxcl1, Cxcl2, and Cxcl5, and hepatic neutrophil infiltration were increased in wild-type mice, but not in TLR2- and TLR9-deficient mice... 
Chemokine | ALD | Binge ethanol feeding | MyD88 | HEPATOCYTE APOPTOSIS | chemokine | PHYSIOLOGY | BONE-MARROW | ATHEROSCLEROSIS | binge ethanol feeding | ADAPTER MOLECULES | HEPATITIS | DISEASE | TOLL-LIKE RECEPTORS | MICE | STEATOHEPATITIS | GASTROENTEROLOGY & HEPATOLOGY | Up-Regulation | Liver - pathology | Toll-Like Receptor 2 - genetics | Toll-Like Receptor 9 - genetics | Hepatic Stellate Cells - metabolism | Hepatocytes - metabolism | Neutrophil Infiltration | Toll-Like Receptor 2 - deficiency | Liver - immunology | Liver Diseases, Alcoholic - genetics | Hepatic Stellate Cells - immunology | Time Factors | Female | Kupffer Cells - metabolism | Chemokine CXCL1 - metabolism | Disease Models, Animal | Liver Diseases, Alcoholic - pathology | Ethanol | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Toll-Like Receptor 9 - deficiency | Cells, Cultured | Liver Diseases, Alcoholic - prevention & control | Binge Drinking | Receptors, Interleukin-8B - immunology | Toll-Like Receptor 2 - metabolism | Hepatocytes - immunology | Liver Diseases, Alcoholic - metabolism | Mice, Knockout | Chemokine CXCL1 - immunology | Animals | Liver Diseases, Alcoholic - immunology | Receptors, Interleukin-8B - metabolism | Toll-Like Receptor 9 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Kupffer Cells - immunology | Medical research | Liver diseases | Liver | Physiological aspects | TLR9 | Medicine, Experimental | Research | Drinking of alcoholic beverages | Health aspects | TLR2 | Analysis | Liver and Biliary Tract
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2018, Volume 49, Issue 6, pp. 1062 - 1076.e6
.... We identified differential and non-redundant roles for the chemokines CXCL1 and CXCL2, governed by their distinct cellular sources... 
endothelium | extravasation | inflammation | pericytes | CXCR2 | ACKR1 | chemokines | neutrophils | CELLS | ADHESION | PROTEIN | TRANSENDOTHELIAL MIGRATION | VENULAR WALLS | MIP-2 | SITES | MICE | IMMUNOLOGY | EXPRESSION | Abdominal Muscles - drug effects | Neutrophils - cytology | Chemokine CXCL1 - genetics | Gene Expression Profiling | Intercellular Junctions - immunology | Transendothelial and Transepithelial Migration - drug effects | Chemokine CXCL2 - genetics | Chemokine CXCL1 - metabolism | Chemokine CXCL2 - metabolism | Neutrophils - metabolism | Duffy Blood-Group System - immunology | Endothelial Cells - metabolism | Abdominal Muscles - immunology | Mice, Inbred C57BL | Gene Expression Regulation | Intercellular Junctions - metabolism | Neutrophils - immunology | Receptors, Cell Surface - metabolism | Mice, Transgenic | Transendothelial and Transepithelial Migration - immunology | Receptors, Cell Surface - immunology | Mice, Knockout | Endothelial Cells - immunology | Abdominal Muscles - metabolism | Chemokine CXCL1 - immunology | Tumor Necrosis Factor-alpha - pharmacology | Chemokine CXCL2 - immunology | Animals | Intercellular Junctions - drug effects | Duffy Blood-Group System - metabolism | Duffy Blood-Group System - genetics | Transendothelial and Transepithelial Migration - genetics | Endothelial Cells - drug effects | Receptors, Cell Surface - genetics | Medical colleges | Emigration and immigration | Endothelium | Diapedesis | Motility | Leukocyte migration | Neutrophils | Muscles | Emigration | Leukocytes (neutrophilic) | Inflammation | Investigations | Endothelial cells | Cell adhesion & migration | Microscopy | Tumor necrosis factor | Pericytes | Ligands | Chemokines | Cell migration
Journal Article