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British journal of pharmacology, ISSN 0007-1188, 2012, Volume 166, Issue 8, pp. 2289 - 2306
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 8/2015, Volume 388, Issue 8, pp. 883 - 903
G-protein coupled receptors (GPCRs) are the targets of over half of all prescribed drugs today... 
Neurosciences | CXCR 1 , CXCR 2 , CCR 4 and CCR 5 , chemokine receptors | TM, trans-membrane helix | β 2 AR, β 2 -adrenergic receptor | ProS, pairwise protein similarity method | CRF1, corticotropin releasing factor receptor 1 | T4L, T4-lysozyme | ECL, extracellular loop | GLP-1, Glucagon-like peptide-1 receptor | hM 3 R, human muscarinic M3 receptor | α1B Adrenergic receptor | Pharmacology/Toxicology | 7TM, seven-transmembrane domain | HGMP, hierarchical GPCR modelling protocol | PDB, Protein Data Bank | XFELs, x-ray free electron lasers | 5-HT 2B and 5-HT 2C , human 5-hydroxytryptamine receptors 2B and 2C, respectively | GLAS, GPCR-likeness assessment score | H 1 , histamine receptor 1 | 3D, three-dimensional | Biomedicine | CCK 2 R, cholecystokinin receptor-2 | MD, molecular dynamic simulations | GPCRs, G-protein coupled receptors | Dopamine D 2 receptor | BRIL, apocytochrome b 562 RIL | δ-OR, delta-opioid receptor | SDM, site-directed mutagenesis | CCK2R, cholecystokinin receptor-2 | PEPTIDE-1 RECEPTOR | DESIGN | CXCR1, CXCR2, CCR4, and CCR5, chemokine receptors | beta 2AR, beta 2-adrenergic receptor | hMR, human muscarinic M3 receptor | HUMAN OREXIN-1 | PHARMACOLOGY & PHARMACY | ANTAGONISTS | Dopamine D-2 receptor | PROTEIN-COUPLED RECEPTORS | SITE-DIRECTED MUTAGENESIS | alpha 1B Adrenergic receptor | LIPIDIC CUBIC PHASE | delta-OR, delta-opioid receptor | 5-HT2B and 5-HT2C, human 5-hydroxytryptamine receptors 2B and 2C, respectively | H-1, histamine receptor 1 | SERIAL FEMTOSECOND CRYSTALLOGRAPHY | BINDING | SELECTIVITY | BRIL, apocytochrome bRIL | Animals | Receptors, G-Protein-Coupled - metabolism | Computer Simulation | Drug Industry | Humans | Cooperative Behavior | Models, Molecular | Crystallography | Drug Discovery | Universities | Drug discovery | BRIL, apocytochrome b562RIL | Meeting Report | H1, histamine receptor 1 | β2AR, β2-adrenergic receptor | CXCR1, CXCR2, CCR4 and CCR5, chemokine receptors | hM3R, human muscarinic M3 receptor | Dopamine D2 receptor
Journal Article
BMC developmental biology, ISSN 1471-213X, 2007, Volume 7, Issue 1, pp. 23 - 23
.... The migration of the primordium is driven by the chemokine SDF1 and by its receptor CXCR4, encoded respectively by the genes sdf1a and cxcr4b... 
SURVIVAL | ZEBRAFISH | METASTASIS | CORECEPTOR | AMPHIBIANS | FISH | POSTEMBRYONIC DEVELOPMENT | DEVELOPMENTAL BIOLOGY | GUIDANCE | CANCER | EXPRESSION | Receptors, G-Protein-Coupled - metabolism | Molecular Sequence Data | Zebrafish - embryology | Cell Movement - genetics | RNA Interference | Gene Expression Regulation, Developmental | Receptors, CXCR | Receptors, CXCR4 - genetics | Receptors, Chemokine - antagonists & inhibitors | Receptors, Chemokine - genetics | Receptors, G-Protein-Coupled - physiology | Amino Acid Sequence | Chemokine CXCL12 | Animals, Genetically Modified | Receptors, CXCR4 - antagonists & inhibitors | Zebrafish Proteins - metabolism | Receptors, Chemokine - metabolism | Zebrafish Proteins - antagonists & inhibitors | Chemokines, CXC - genetics | Zebrafish - genetics | Zebrafish Proteins - physiology | Receptors, CXCR4 - metabolism | Sequence Homology, Amino Acid | Receptors, CXCR4 - physiology | Animals | Receptors, Chemokine - physiology | Lateral Line System - embryology | Models, Biological | Chemokines, CXC - metabolism | Embryo, Nonmammalian | Receptors, G-Protein-Coupled - antagonists & inhibitors | Receptors, G-Protein-Coupled - genetics | Zebrafish Proteins - genetics | Antagonists (Biochemistry) | Control | Research | Developmental biology | Cell migration | Chemokine receptors | Chemokines, CXC | Receptors, G-Protein-Coupled | Zebrafish Proteins | Zebrafish | Life Sciences | Lateral Line System | Development Biology | Receptors, Chemokine | Receptors, CXCR4 | Cell Movement
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 5/2011, Volume 108, Issue 20, pp. 8485 - 8490
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2012, Volume 132, Issue 1, pp. 216 - 225
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2019, Volume 50, Issue 2, pp. 378 - 389.e5
Currently, we lack an understanding of the individual and combinatorial roles for chemokine receptors in the inflammatory process... 
mouse models | monocytes | dendritic cells | receptors | chemokines | inflammation | CELLS | RECRUITMENT | NEUTROPHIL MIGRATION | ROLES | BONE-MARROW | TISSUE | HOST-DEFENSE | MONOCYTE SUBSETS | IMMUNOLOGY | EXPRESSION | CCR2 | Eosinophils - metabolism | Receptors, CCR - metabolism | Receptors, CCR3 - immunology | Receptors, CCR2 - immunology | Monocytes - metabolism | Monocytes - immunology | Eosinophils - immunology | Receptors, CCR5 - immunology | Inflammation - metabolism | Receptors, CCR5 - metabolism | Lymphocytes - immunology | Receptors, CCR1 - immunology | Neutrophils - metabolism | Chemokines - immunology | Lymphocytes - metabolism | Mice, Inbred C57BL | Receptors, CCR - genetics | Neutrophils - immunology | Gene Expression Profiling - methods | Inflammation - immunology | Mice, Knockout | Receptors, CCR3 - metabolism | Receptors, CCR2 - metabolism | Animals | Receptors, CCR - immunology | Receptors, CCR1 - metabolism | Inflammation - genetics | Chemokines - metabolism | Mice, Inbred BALB C | Medicine, Experimental | Medical research | Dendritic cells | Lymphocytes | Analysis | CC chemokine receptors | CCR5 protein | Statistical analysis | Redundancy | Leukocytes (eosinophilic) | Leukocytes (neutrophilic) | Inflammation | Chemokine receptors | Recruitment | CCR1 protein | White blood cells | Monocytes | Receptors | Clonal deletion | CCR2 protein | Rodents | Animal tissues | Mice | Chromosomes | Chemokines | Monocyte chemoattractant protein 1 | Combinatorial analysis
Journal Article
Journal Article