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European Journal of Pharmacology, ISSN 0014-2999, 2003, Volume 462, Issue 1, pp. 193 - 198
The cytokine interleukin-17 may play a role in the recruitment of airway neutrophils, and interleukin-17 protein is increased in the airways of patients with... 
C-X-C chemokine | Interleukin-17 | Bronchial epithelial cell | human | Human | ACTIVATION | PROTEIN | MECHANISMS | CYTOKINE | NEUTROPHIL RECRUITMENT | bronchial epithelial cell, human | interleukin-17 | IN-VITRO | IL-17 | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | AIRWAYS | CYCLOSPORINE | Epithelial Cells - metabolism | Albuterol - pharmacology | Cyclosporine - pharmacology | Epithelial Cells - drug effects | Humans | Receptors, Glucocorticoid - metabolism | Interleukin-17 - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Bronchi - drug effects | Dose-Response Relationship, Drug | Calcineurin Inhibitors | Bronchi - metabolism | Interleukin-8 - secretion | Flavonoids - pharmacology | Intercellular Signaling Peptides and Proteins - secretion | Receptors, Adrenergic, beta - drug effects | Receptors, Adrenergic, beta - metabolism | Receptors, Glucocorticoid - drug effects | Bronchi - cytology | Chemotactic Factors - secretion | p38 Mitogen-Activated Protein Kinases | Chemokines - secretion | Enzyme Inhibitors - pharmacology | Adrenergic beta-Agonists - pharmacology | Imidazoles - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Chemokines, CXC - secretion | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Chemokine CXCL1 | Hydrocortisone - pharmacology | Pyridines - pharmacology | Chemokine CXCL6 | Cell Line, Transformed | Index Medicus | Chemokines/secretion | Albuterol/pharmacology | Flavonoids/pharmacology | Adrenergic | beta/drug effects/metabolism | Epithelial Cells/drug effects/metabolism | Enzyme Inhibitors/pharmacology | Transformed | Adrenergic beta-Agonists/pharmacology | Ca(2+)-Calmodulin Dependent Protein Kinase/antagonists & inhibitors | Receptors | Imidazoles/pharmacology | Chemotactic Factors/secretion | Cyclosporine/pharmacology | Lungmedicin och allergi | Respiratory Medicine and Allergy | Bronchi/cytology/drug effects/metabolism | Drug | Intercellular Signaling Peptides and Proteins/secretion | Cell Line | P-Glycoprotein/antagonists & inhibitors | Interleukin-8/secretion | Hydrocortisone/pharmacology | Glucocorticoid/drug effects/metabolism | CXC/secretion | Interleukin-17/pharmacology | Mitogen-Activated Protein Kinases/antagonists & inhibitors | Calcineurin/antagonists & inhibitors | Dose-Response Relationship | Chemokines | Pyridines/pharmacology
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 08/2003, Volume 93, Issue 4, pp. 311 - 320
ABSTRACT—Homocysteine (Hcy) is an independent risk factor for cardiovascular disease. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are... 
Monocyte chemoattractant protein-1 | Monocytes | Homocysteine | Interleukin-8 | Atherosclerosis | homocysteine | atherosclerosis | monocytes | ENDOTHELIAL-CELL INJURY | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | monocyte chemoattractant protein-1 | RISK FACTOR | PLASMA HOMOCYST(E)INE | interleukin-8 | VASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | ATHEROMATOUS PLAQUES | HEMATOLOGY | NF-KAPPA-B | T-LYMPHOCYTES | Interleukin-8 - genetics | Reactive Oxygen Species - metabolism | Chemokine CCL2 - secretion | Monocytes - cytology | Humans | Dimethyl Sulfoxide - pharmacology | Monocytes - metabolism | RNA, Messenger - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Thiocarbamates - pharmacology | Chromans - pharmacology | Time Factors | Homocysteine - pharmacology | Indoles - pharmacology | Interleukin-8 - secretion | Flavonoids - pharmacology | RNA, Messenger - drug effects | RNA, Messenger - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Chemokine CCL2 - genetics | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Monocytes - drug effects | Genistein - pharmacology | Pyridines - pharmacology | Thiazoles - pharmacology | Thiazolidinediones | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e58129 - e58129
Chemokines and chemokine receptor-mediated effects are important mediators of the immunological response and cure in human leishmaniasis. However, in addition... 
IMMUNITY | EXPRESSION | HUMAN MACROPHAGES | MULTIDISCIPLINARY SCIENCES | Chemokine CXCL6 - pharmacology | Anti-Infective Agents - pharmacology | Chemokine CXCL9 - pharmacology | Humans | Chemokine CCL3 - pharmacology | Chemokine CCL20 - pharmacology | Peptides - pharmacology | Chemokine CCL27 - pharmacology | Chemokine CXCL10 - pharmacology | Chemokine CCL2 - pharmacology | Antiparasitic Agents - pharmacology | Interleukin-8 - pharmacology | Chemokine CXCL2 - pharmacology | Chemokines - pharmacology | Leishmania mexicana - drug effects | Peptides | Leishmaniasis | Flow cytometry | Antimicrobial activity | Cytotoxicity | Propidium iodide | Infections | Parasites | Leukocytes | Antiinfectives and antibacterials | Immunity | Fungi | Mitochondria | Immunology | Parasitic diseases | Antimicrobial peptides | CCL20 protein | Drug dosages | Vector-borne diseases | Scanning electron microscopy | Antigens | Immune response | Iodides | CCL3 protein | Antimicrobial agents | Electron microscopy | White blood cells | Medicine | Cytometry | Signaling | CXCL10 protein | Chemokines | Monocyte chemoattractant protein 1 | Index Medicus | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Infektionsmedicin | Infectious Medicine | Lungmedicin och allergi | Klinisk medicin | Respiratory Medicine and Allergy
Journal Article
Nature, ISSN 0028-0836, 12/2016, Volume 540, Issue 7633, pp. 344 - 345
Structures of two chemokine receptor proteins in complex with small molecules reveal a previously unknown binding pocket that could be a drug target for... 
COMPLEX | ACTIVATION | RECOGNITION | PROTEIN-COUPLED RECEPTOR | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CXCR4 | ADRENERGIC-RECEPTOR | CHEMOKINE | Humans | Pharmacology | Physiological aspects | Protein structure prediction | Structure | Methods | Membrane proteins | Index Medicus
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 10/2005, Volume 82, Issue 1, pp. 51 - 62
Chemokines are important mediators in immune responses and inflammatory processes. Calcitonin gene‐related peptide (CGRP) is produced in dorsal root ganglion... 
CCL2 | CXCL1 | calcitonin gene‐related peptide | dorsal root ganglion | CHEMOKINE RECEPTOR CXCR2 | PROTEIN-KINASE-C | CALCIUM-IONS | ALZHEIMERS-DISEASE | calcitonin gene-related peptide | DORSAL-ROOT GANGLION | NEUROSCIENCES | RAT SKIN | SIGNAL-TRANSDUCTION | NEUROPATHIC PAIN | OPIOID RECEPTORS | SUBSTANCE-P | Chemokines, CXC - immunology | Calcium - metabolism | Chemokine CCL2 - immunology | Nociceptors - physiology | Ganglia, Spinal - cytology | Dose-Response Relationship, Drug | GTP-Binding Protein alpha Subunits, Gi-Go - immunology | Drug Interactions | omega-Conotoxin GVIA - pharmacology | Time Factors | Chemokines, CXC - pharmacology | Calcitonin Gene-Related Peptide - metabolism | Ryanodine - pharmacology | Pertussis Toxin - pharmacology | Animals, Newborn | Neurons, Afferent - drug effects | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Pain Measurement - drug effects | Chelating Agents - pharmacology | Calcium Channel Blockers - pharmacology | GTP-Binding Protein alpha Subunits, Gi-Go - pharmacology | Antibodies - pharmacology | Pain Measurement - methods | Animals | Egtazic Acid - pharmacology | Analysis of Variance | Chemokine CCL2 - pharmacology | Intercellular Signaling Peptides and Proteins - pharmacology | Thapsigargin - pharmacology | Chemokine CXCL1 | Neurons, Afferent - metabolism | Radioimmunoassay - methods | Intercellular Signaling Peptides and Proteins - immunology | Index Medicus
Journal Article
Immunology, ISSN 0019-2805, 07/2010, Volume 130, Issue 3, pp. 399 - 409
Calcitonin gene‐related peptide (CGRP) is widely distributed and plays important roles in a wide array of biological functions. It is enriched in primary... 
cytokine | macrophage | chemokine | enzyme‐linked immunosorbent assay | neuropeptide | Chemokine | Neuropeptide | Enzyme-linked immunosorbent assay | Cytokine | Macrophage | TRIGEMINAL GANGLION | ALVEOLAR EPITHELIAL-CELLS | NECROSIS-FACTOR-ALPHA | ADRENOMEDULLIN RECEPTORS | IMMUNOLOGY | RAT SENSORY NEURONS | HUMAN MONOCYTES | CYTOKINE PRODUCTION | enzyme-linked immunosorbent assay | RECEPTOR-LIKE RECEPTOR | NF-KAPPA-B | ACTIVITY-MODIFYING PROTEIN-1 | Interleukin-6 - antagonists & inhibitors | Nitriles - pharmacology | Receptor, trkA - antagonists & inhibitors | Receptor, trkA - immunology | Intracellular Signaling Peptides and Proteins - immunology | Peptide Fragments - pharmacology | Calcitonin Receptor-Like Protein | Nitrobenzenes - pharmacology | Sulfones - pharmacology | Nerve Growth Factor - antagonists & inhibitors | I-kappa B Proteins - antagonists & inhibitors | Receptors, Calcitonin - antagonists & inhibitors | Antibodies - immunology | Toll-Like Receptor 4 - agonists | Calcitonin Gene-Related Peptide - metabolism | Interleukin-1beta - antagonists & inhibitors | Cell Line | Dinoprostone - pharmacology | Cyclooxygenase 2 Inhibitors - pharmacology | Cytokines - metabolism | Calcitonin Gene-Related Peptide - pharmacology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Interleukin-1beta - immunology | Membrane Proteins - immunology | Sulfonamides - pharmacology | Piperazines - pharmacology | Cycloheximide - pharmacology | Antibodies - pharmacology | Macrophages - metabolism | Animals | Receptors, Calcitonin - immunology | Membrane Proteins - antagonists & inhibitors | Interleukin-6 - immunology | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Receptor Activity-Modifying Proteins | Chemokines - metabolism | Mice | Kinetics | Quinazolines - pharmacology | Dactinomycin - pharmacology | Peptides | Immunotherapy | Prostaglandins E | Nerve growth factor | Inflammation | Macrophages | Mitogens | Cytokines | Rodents | Immune system | Index Medicus | Original
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 06/2017, Volume 325, pp. 61 - 70
Estrogen receptors (ERs) α and β are distributed in most tissues of women and men. ERs are bound by estradiol (E2), a natural hormone, and mediate the... 
PC12 | Phytoestrogens | SERM | Proliferation | Differentiation | Breast cancer cell lines | ENDOCRINE-DISRUPTING CHEMICALS | SURVIVAL | SIGNALING PATHWAYS | ALPHA | NERVE GROWTH-FACTOR | PHARMACOLOGY & PHARMACY | TOXICOLOGY | PC12 CELLS | EXPRESSION | ZEARALENONE | Adrenal Gland Neoplasms - drug therapy | Transcription, Genetic - drug effects | Humans | Isoflavones - pharmacology | Stilbenes - pharmacology | PC12 Cells | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Chemokine CXCL12 - genetics | Transfection | MCF-7 Cells | Pheochromocytoma - pathology | Estrogen Receptor alpha - metabolism | Female | Neurogenesis - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Adrenal Gland Neoplasms - pathology | Neurites - drug effects | Phytoestrogens - pharmacology | Pheochromocytoma - metabolism | Response Elements | Rats | Neurites - metabolism | Breast Neoplasms - drug therapy | Estrogen Receptor alpha - drug effects | Nerve Tissue Proteins - metabolism | Neurites - pathology | Pheochromocytoma - drug therapy | Animals | Breast Neoplasms - genetics | Chemokine CXCL12 - metabolism | Estrogen Receptor alpha - genetics | Diet | Breast Neoplasms - pathology | Adrenal Gland Neoplasms - metabolism | Pheochromocytoma - genetics | Cell Proliferation - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Adrenal Gland Neoplasms - genetics | Selective Estrogen Receptor Modulators - pharmacology | Apigenin - pharmacology | Zearalenone - pharmacology | Analysis | Resveratrol | Phenols | Nerve growth factor | Hormones | Cell differentiation | Estradiol | Isoflavones | Therapeutics | Homeopathy | Materia medica and therapeutics | Index Medicus | Life Sciences | Toxicology | Pharmacology | Pharmaceutical sciences | PUBLIC HEALTH | GROWTH FACTORS | MAMMARY GLANDS | NEOPLASMS | NERVES | ESTRADIOL | PHENOTYPE | CELL PROLIFERATION | ANIMAL TISSUES | RECEPTORS | 60 APPLIED LIFE SCIENCES | BRAIN
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 08/2013, Volume 94, Issue 2, pp. 213 - 222
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2001, Volume 276, Issue 27, pp. 25096 - 25100
Leptin, a circulating hormone secreted mainly from adipose tissues, is involved in the control of body weight. The plasma concentrations are correlated with... 
CYTOSKELETAL COMPONENTS | DIABETES-MELLITUS | INSULIN-RESISTANCE | OBESE GENE | GLUCOSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATHEROSCLEROSIS | NECROSIS-FACTOR-ALPHA | MICE | CARNITINE PALMITOYLTRANSFERASE-I | VASCULAR-DISEASE |