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Oncotarget, ISSN 1949-2553, 04/2018, Volume 9, Issue 26, pp. 18115 - 18127
Cytarabine is a conventionally used chemotherapeutic agent for treating acute myeloid leukemia (AML). However, chemoresistance, toxic side-effects and poor... 
Heteronemin | Farnesyl transferase | Chemosensitization | Ras | Acute myeloid leukemia
Journal Article
Oncotarget, ISSN 1949-2553, 04/2018, Volume 9, Issue 26, pp. 18351 - 18366
Hypoxia is a characteristic of solid tumors especially Glioblastoma and is critical to chemoresistance. Cancer stem cells present in hypoxic niches are known... 
Hypoxia | COX-2 inhibitor | Chemosensitization | BCNU | PGE
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2009, Volume 17, Issue 3, pp. 1222 - 1231
Two highly selective and potent receptor ligands, - and - were synthesized. - significantly increases the ability of doxorubicin to kill breast tumor cells at... 
Sigma-2 ligands | PET radiotracers | Chemosensitization | Cancer
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 3/2012, Volume 10, Issue 3, pp. 369 - 377
The Fanconi Anemia (FA) pathway is required for repair of DNA interstrand crosslinks (ICLs). FA pathway-deficient cells are hypersensitive to DNA ICL-inducing... 
Fanconi Anemia | Chemosensitization | Nedd8
Journal Article
Oncotarget, 2017, Volume 8, Issue 9, pp. 14736 - 14747
Journal Article
Cancer Biology and Therapy, ISSN 1538-4047, 07/2012, Volume 13, Issue 9, pp. 804 - 811
Journal Article
JOURNAL OF THORACIC ONCOLOGY, ISSN 1556-0864, 10/2018, Volume 13, Issue 10, pp. S521 - S521
Conference Proceeding
ChemMedChem, ISSN 1860-7179, 02/2017, Volume 12, Issue 4, pp. 279 - 279
The front cover picture shows the ability of nontoxic organoiridium complexes to selectively chemosensitize cancer cells toward clinically used platinum... 
chemosensitization | iridium catalysis | cancer | drug discovery | biocatalysis | Rodents | Cancer
Journal Article
Journal Article
RSC Advances, ISSN 2046-2069, 2016, Volume 6, Issue 107, pp. 105871 - 105877
Nitric oxide (NO) as a chemosensitizer has attracted a lot of attention in anti-multidrug resistance (MDR) tumor therapy. In this study, a three-segment... 
CELLS | NANOPARTICLES | EFFICACY | IN-VIVO | DOXORUBICIN | NANOMEDICINE | RELEASE | MULTIDRUG-RESISTANCE | CHEMOSENSITIZATION | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | Therapy | Synthesis (chemistry) | Copolymers | Toxicity | Nitric oxide | Biocompatibility | Nanostructure | Tumors
Journal Article
Science of the Total Environment, ISSN 0048-9697, 04/2016, Volume 548-549, pp. 317 - 324
Journal Article
Molecular and Cellular Pharmacology, ISSN 1938-1247, 2009, Volume 1, Issue 1, pp. 29 - 43
Inflammation is closely linked to cancer, and many anti-cancer agents are also used to treat inflammatory diseases, such as rheumatoid arthritis. Moreover,... 
COX-2 inhibitor | Chemoprotection | Corticosteroids | NSAID | Inflammation | Chemosensitization | Pharmacokinetics | Anti-inflammatory agents | Carcinogenesis | Cancer | Anti-Inflammatory agents
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 05/2018, Volume 151, pp. 508 - 519
EF24 and both were effective monocarbonyl curcumin analogues (MCACs) with excellent anti-tumor activity, however, drug defect such as toxicity may limit their... 
Synthesis | Anti-tumor activities | Chemosensitization | Toxicity | MCACs | APOPTOSIS | CELLS | CHEMISTRY, MEDICINAL | EF24 | CURCUMIN | ANTITUMOR | OXYGEN SPECIES ROS | MONO-CARBONYL ANALOGS | AGENTS | STRESS | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 4, pp. 1433 - 1438
The major obstacle in cancer treatment is the resistance of cancer cells to therapies. Nrf2 is a transcription factor that regulates a cellular defense... 
Cell growth | Chemotherapy | Cell death | Cell lines | HeLa cells | Sensitization | Heterologous transplantation | Tumors | Lung neoplasms | Cancer | Reactive oxygen species | Antioxidant response | Chemosensitization | Natural compounds | CANCER-CELLS | natural compounds | INCREASED EXPRESSION | MULTIDISCIPLINARY SCIENCES | chemosensitization | ANTI-TUMOR AGENTS | KEAP1 | antioxidant response | BRUCEOSIDE-A | LUNG-CANCER | NRF2 | CUL3-BASED E3 LIGASE | reactive oxygen species | SQUAMOUS-CELL CARCINOMAS | SUBSTRATE ADAPTER PROTEIN | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Glutathione - metabolism | Humans | Lung Neoplasms - metabolism | Immunoblotting | Lung Neoplasms - pathology | Antineoplastic Agents - administration & dosage | Cisplatin - administration & dosage | Quassins - pharmacology | Quassins - chemistry | Ubiquitination - drug effects | Antineoplastic Agents - pharmacology | Molecular Structure | Intracellular Space - drug effects | Quassins - administration & dosage | Cisplatin - pharmacology | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Intracellular Space - metabolism | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | HeLa Cells | Physiological aspects | Drug resistance | Patient outcomes | Proteins | Tissue | Survival analysis | Gene expression | Cells | Apoptosis | Index Medicus | Biological Sciences
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 35, pp. 58801 - 58808
Changes in pH can alter the uptake of chemotherapy drugs. Proton pump inhibitors (PPIs) may therefore increase the chemosensitivity of cancer cells and... 
PPI | CapeOx | Chemosensitization | FOLFOX | 5-FU | CELLS | capeOx | RESISTANCE | chemosensitization | CARCINOMA | TUMORS | CHEMOTHERAPY | PPIS | CELL BIOLOGY
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2019, Volume 293, pp. 84 - 93
Chemosensitization strategies have been used to sensitize cancer cells to conventional drugs, but their utility is often obstructed by additional off-target... 
Human serum albumin | Signal transduction | Chemosensitization | Receptor crosslinking | Drug-free macromolecular therapeutics | APOPTOSIS | MOBILIZATION | DEATH RECEPTOR 5 | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | CALCIUM INFLUX | NANOPARTICLES | THERAPY | PHARMACOLOGY & PHARMACY | AGONIST ANTIBODY
Journal Article
AIP Conference Proceedings, ISSN 0094-243X, 01/2019, Volume 2063, Issue 1
The paper reports the first results of vegetation experiments confirming the earlier observed in vitro sensitizing activity of extracellular elicitors of F.... 
chemosensitization | Parastagonospora nodorum | Stagonospora leaf and glume blotch of wheat | triazole fungicides | Sensitizing | Fungicides | Metabolites | Triazoles | Wheat
Journal Article
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