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Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9972, pp. 956 - 965
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 4, pp. 751 - 761.e8
Journal Article
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2015, Volume 62, Issue 6, pp. 1398 - 1404
Graphical abstract 
Gastroenterology and Hepatology | 3-hydroxy-3-methylglutaryl-CoA reductase | Stearoyl-CoA desaturase | Non-alcoholic fatty liver disease | Lipogenesis | FGF19 | 3-hydroxy-3-methylglutaryl- CoA reductase | FXR | NONALCOHOLIC STEATOHEPATITIS | AGONISTS | NUCLEAR RECEPTOR | CHOLESTEROL-METABOLISM | TRANSPORT | FEEDBACK-REGULATION | LIVER | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | ADIPOSE-TISSUE | Ursodeoxycholic Acid - administration & dosage | Oleic Acid - metabolism | Bile Acids and Salts - biosynthesis | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Intra-Abdominal Fat - metabolism | Obesity, Morbid - drug therapy | Non-alcoholic Fatty Liver Disease - drug therapy | Ursodeoxycholic Acid - pharmacology | Stearoyl-CoA Desaturase - biosynthesis | Liver - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Lipid Metabolism - drug effects | Intra-Abdominal Fat - drug effects | Obesity, Morbid - metabolism | Physiological aspects | Obesity | Ursodiol | Deoxycholic acid | Index Medicus | BAs, bile acids | nCEH, neutral cholesterol ester hydrolase | ApoB, apolipoprotein B | LDLR, low density lipoprotein receptor | FGF19, fibroblast growth factor 19 | VLDL, very low density lipoproteins | ABC, ATP-binding cassette | TGs, triglycerides | NAFLD, non-alcoholic fatty liver disease | OA, oleic acid | C4, 7α-hydroxy-4-cholesten-3-one | SHP, small heterodimer partner | SREBP1c, sterol regulatory element-binding protein-1c | CA, cholic acid | PA, palmitic acid | FATP1, fatty acid transport protein 1 | UDCA, ursodeoxycholic acid | FAs, fatty acides | HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase | vWAT, visceral white adipose tissue | SCD, stearoyl-Coa desaturase | CYP7A1, cholesterol 7α-hydroxylase | NASH, non-alcoholic steatohepatitis | FXR, farnesoid X receptor | CDCA, chenodeoxycholic acid | MA, myristic acid | FASN, fatty acid synthase | MTTP, microsomal triglyceride transfer protein | SA, stearic acid | NONALCOHOLIC | FATTY LIVER-DISEASE | Gastroenterology & Hepatology | Endokrinologi och diabetes | STEATOHEPATITIS | PLACEBO-CONTROLLED TRIAL | COA DESATURASE | Endocrinology and Diabetes
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 09/2011, Volume 106, Issue 9, pp. 1638 - 1645
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2016, Volume 113, Issue 6, pp. 1600 - 1605
Journal Article
GUT, ISSN 0017-5749, 09/2003, Volume 52, Issue 9, pp. 1371 - 1375
Background: Whether ileal absorption of bile acid is up or downregulated in chronic cholestasis is still debated, and most evidence has come from animal... 
ILEAL RESECTION | TRANSPORTER | METABOLISM | DOWN-REGULATION | CHOLESTASIS | ENTEROHEPATIC CIRCULATION | CHENODEOXYCHOLIC ACID | LIVER-DISEASE | CHOLECYSTECTOMY | GASTROENTEROLOGY & HEPATOLOGY | ADAPTIVE RESPONSE
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 04/2010, Volume 51, Issue 4, pp. 771 - 784
The farnesoid X receptor (FXR) is a bile acid activated nuclear receptor. Zucker (fa/fa) rats, harboring a loss of function mutation of the leptin receptor,... 
RESPONSE ELEMENT | TYROSINE PHOSPHORYLATION | METABOLISM | LINKING OBESITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | ANIMAL-MODELS | FARNESOID-X-RECEPTOR | NONALCOHOLIC STEATOHEPATITIS | MECHANISMS | AGONISTS | Liver - pathology | Fatty Liver - pathology | Male | Muscle, Skeletal - metabolism | Insulin Receptor Substrate Proteins - metabolism | RNA, Messenger - metabolism | Thiazolidinediones - administration & dosage | Obesity - blood | Thiazolidinediones - therapeutic use | Hypoglycemic Agents - administration & dosage | Liver - drug effects | Time Factors | Lipids - blood | Muscle, Skeletal - drug effects | Chenodeoxycholic Acid - therapeutic use | Lipid Metabolism - genetics | Phosphorylation - drug effects | Drug Therapy, Combination | Disease Models, Animal | Hypoglycemic Agents - therapeutic use | Fatty Liver - blood | Obesity - complications | Liver - metabolism | Fatty Liver - prevention & control | Insulin Resistance | Rats | Chenodeoxycholic Acid - administration & dosage | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Random Allocation | Chenodeoxycholic Acid - analogs & derivatives | Gene Expression Regulation - drug effects | Rats, Zucker | Animals | Hypolipidemic Agents - administration & dosage | Lipid Metabolism - drug effects | Hypolipidemic Agents - therapeutic use | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article