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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 138, Issue 1, pp. 61 - 75
Background Disease heterogeneity in patients with severe asthma and its relationship to inflammatory mechanisms remain poorly understood. Objective We aimed to... 
Allergy and Immunology | phenotype | endotype | topological data analysis | chitinase 3–like protein 1 | eosinophils | matrix metalloproteinase | cytokines | neutrophils | heterogeneity | Asthma | SPUTUM | LUNG-FUNCTION | PHENOTYPES | RESEARCH-PROGRAM | IMMUNOLOGY | IDENTIFICATION | YKL-40 | CLUSTER-ANALYSIS | chitinase 3-like protein 1 | OBSTRUCTIVE PULMONARY-DISEASE | ALLERGY | MICE | EXPRESSION | Asthma - diagnosis | Severity of Illness Index | Asthma - metabolism | Cytokines - metabolism | Humans | Middle Aged | Risk Factors | Male | Asthma - drug therapy | Matrix Metalloproteinase Inhibitors - metabolism | Case-Control Studies | Sputum - metabolism | Chitinase-3-Like Protein 1 - metabolism | Young Adult | Bayes Theorem | Inflammation Mediators - metabolism | Biomarkers | Adult | Female | Aged | Matrix Metalloproteinases - metabolism | Respiratory Function Tests | Medical colleges | Care and treatment | Hospitals | Respiratory agents | Research institutes | Pharmaceutical industry | Medicine, Experimental | Medical research | Information management | Analysis | Datasets | Biomedical research | Questionnaires | Neutrophils | Software | Patients | Methods | Quality of life | ECP, Eosinophil cationic protein | K-S, Kolmogorov-Smirnov | MMP, Matrix metalloproteinase | ACQ, Asthma Control Questionnaire | Feno, Fraction of exhaled nitric oxide | HAD, Hospital Anxiety and Depression | YKL-40, Chitinase 3–like protein 1 | Asthma and Lower Airway Disease | TDA, Topological data analysis | FGF, Fibroblast growth factor | GINA, Global Initiative for Asthma | ICS, Inhaled corticosteroid
Journal Article
Anticancer Research, ISSN 0250-7005, 08/2018, Volume 38, Issue 8, pp. 4753 - 4758
Background/Aim: YKL-40 plays a role in proliferation and differentiation of malignant cells. The aim of this study was to examine whether YKL-40 is expressed... 
SCC | Squamous cell skin cancer | YKL-40 | Expression | Chitinase-3-like protein | MIGRATION | expression | ONCOLOGY | SERUM YKL-40 | GENE-EXPRESSION | squamous cell skin cancer | CARCINOMA
Journal Article
Experimental Eye Research, ISSN 0014-4835, 11/2019, Volume 188, p. 107791
MicroRNAs (miRNAs) have been shown to play critical roles in the pathogenesis and progression of degenerative retinal diseases like age-related macular... 
Retinal degeneration | Autophagy | RPE | MicroRNA-24 | Chitinase-3-like protein 1
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 05/2014, Volume 459, Issue 3, pp. 479 - 488
CHI3L1 (chitinase-3-like protein 1) is a glycoprotein consisting of 383 amino acids with a molecular mass of 40 kDa, and its serum level is elevated in... 
HUMAN CARTILAGE GLYCOPROTEIN-39 | KAPPA-B KINASE | skeletal muscle cell | BIOCHEMISTRY & MOLECULAR BIOLOGY | myokine | NECROSIS-FACTOR-ALPHA | YKL-40 | SYNOVIAL-CELLS | ACTIVATED RECEPTOR 2 | chitinase-3-like protein 1 (CHI3L1) | TISSUE RESPONSES | inflammation | tumour necrosis factor alpha (TNF alpha) | ARTICULAR CHONDROCYTES | TRANSCRIPTIONAL REGULATION | MAMMALIAN MEMBER | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Humans | Receptor, PAR-2 - metabolism | Tumor Necrosis Factor-alpha - genetics | Male | Muscle, Skeletal - metabolism | NF-kappa B - metabolism | Muscle Fibers, Skeletal - metabolism | Muscle, Skeletal - cytology | Chitinase-3-Like Protein 1 | Young Adult | Lectins - metabolism | Receptor, PAR-2 - antagonists & inhibitors | Muscle, Skeletal - immunology | Adipokines - genetics | Adult | Female | Cell Differentiation | Chemokine CCL2 - metabolism | Interleukin-8 - metabolism | Cytokines - genetics | Interleukin-6 - metabolism | Receptor, PAR-2 - genetics | Recombinant Proteins - metabolism | NF-kappa B - antagonists & inhibitors | Cytokines - metabolism | Signal Transduction | Cells, Cultured | Insulin Resistance | Adipokines - metabolism | Muscle Fibers, Skeletal - immunology | Adolescent | Lectins - genetics | Muscle Fibers, Skeletal - cytology | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
Neurochemistry International, ISSN 0197-0186, 03/2019, Volume 124, pp. 62 - 67
The mechanisms of the pathogenesis of epilepsy remain unclear. Recent research shows that the inflammatory process occurring in the brain may be a common and... 
Biomarker | Drug-resistant epilepsy | Chitinase-3-like protein 1 | TEMPORAL-LOBE EPILEPSY | INTERLEUKIN-1-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CEREBROSPINAL-FLUID | NEUROSCIENCES | SEIZURES | MICROGLIA | SERUM YKL-40 | INFLAMMATION | CONTRIBUTES | EXPRESSION | BRAIN
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 08/2018, Volume 119, Issue 8, pp. 6795 - 6805
Chitinase 3‐like protein 1 (CHI3L1) is a novel biomarker of systemic inflammation. However, the effects of CHI3L1 on the progression of atherosclerosis remain... 
apoptosis | chitinase 3‐like protein 1 | peroxisome proliferator‐activated receptor delta | inflammation | HUVECs | oxygen‐regulated protein 150 | chitinase 3-like protein 1 | oxygen-regulated protein 150 | peroxisome proliferator-activated receptor delta | FOLLISTATIN-LIKE 1 | MYOCARDIAL-INFARCTION | HUMAN CARTILAGE GP-39 | BIOCHEMISTRY & MOLECULAR BIOLOGY | LDLR-/-MICE | ENDOPLASMIC-RETICULUM STRESS | ADHESION MOLECULES | ACUTE CORONARY SYNDROME | CELL BIOLOGY | REDUCES ATHEROSCLEROSIS | ENDOTHELIAL-CELLS | SMOOTH-MUSCLE CELLS | Human Umbilical Vein Endothelial Cells | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Atherosclerosis - pathology | Lipopolysaccharides - toxicity | Atherosclerosis - chemically induced | Atherosclerosis - genetics | Humans | Tumor Necrosis Factor-alpha - genetics | THP-1 Cells | Chemokine CCL2 - genetics | NF-kappa B - metabolism | Chitinase-3-Like Protein 1 - genetics | Atherosclerosis - metabolism | Chitinase-3-Like Protein 1 - metabolism | Inflammation - metabolism | NF-kappa B - genetics | Endoplasmic Reticulum Stress | Inflammation - genetics | Chemokine CCL2 - metabolism | PPAR delta - metabolism | PPAR delta - genetics | Stresses | Chitinase | Phosphorylation | Cytokines | Secretion | Inflammation | siRNA | Tumor necrosis factor-α | Adhesion | Molecular chains | Stress | Endothelium | Cell adhesion molecules | Lipopolysaccharides | Proteins | Ribonucleic acids | Arteriosclerosis | Atherosclerosis | Biomarkers | Bioindicators | Endoplasmic reticulum | Nuclear reactions | Apoptosis
Journal Article
Ophthalmologica, ISSN 0030-3755, 01/2019, Volume 241, Issue 2, pp. 90 - 97
Purpose: To determine whether serum chitinase-3-like protein 1 (CHI3L1) and interleukin-6 (IL-6) levels correlate with serous retinal detachment (SRD) in... 
Research Article | Serum | Diabetes mellitus | Diabetic macular edema | Chitinase-3-like protein 1 | ELISA | Interleukin-6 | RHEUMATOID-ARTHRITIS | CYTOKINES | MARKER | IL-6 | YKL-40 LEVELS | FLUID | OPHTHALMOLOGY | RETINOPATHY | TNF-ALPHA | INFLAMMATORY FACTORS
Journal Article
In Vivo, ISSN 0258-851X, 01/2019, Volume 33, Issue 1, pp. 141 - 143
Background/Aim: Hidradenitis suppurativa (HS) is a chronic disease. Recently, we suggested, chitinase-3-like protein 1 (YKL-40) as a new biomarker for HS since... 
hidradenitis suppurativa | tissue expression | biomarker | YKL-40 | inflammation | Chitinase-3-like protein 1 | BIOMARKERS | MEDICINE, RESEARCH & EXPERIMENTAL | MARKER
Journal Article