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International Journal of Pharmaceutics, ISSN 0378-5173, 11/2016, Volume 513, Issue 1-2, pp. 636 - 647
Antimicrobial chitosan–polyethylene oxide (CS-PEO) nanofibrous mats containing ZnO nanoparticles (NPs) and hydrocortisone-imipenem/cilastatin-loaded ZnO NPs... 
Electrospinning | Antimicrobial activity | Hydrocortisone | Chitosan–polyethylene oxide nanofibrous mat | Imipenem/cilastatin | Zinc oxide nanoparticles | ANTIBACTERIAL ACTIVITIES | CARCINOMA CELLS | WOUND-DRESSING MATERIALS | ELECTROSPUN NANOFIBERS | X-RAY-DIFFRACTION | SILVER NANOPARTICLES | Chitosan-polyethylene oxide nanofibrous mat | COMPOSITE NANOFIBERS | ZNO NANOPARTICLES | PHARMACOLOGY & PHARMACY | ANTIMICROBIAL APPLICATION | NANOCOMPOSITE MATS | Nanoparticles - chemistry | Escherichia coli - drug effects | Delayed-Action Preparations - chemistry | Polyethylene Glycols - chemistry | Delayed-Action Preparations - administration & dosage | Drug Delivery Systems | Hydrocortisone - administration & dosage | Hydrocortisone - chemistry | Nanofibers - administration & dosage | Zinc Oxide - chemistry | Anti-Bacterial Agents - chemistry | Anti-Inflammatory Agents - administration & dosage | Escherichia coli - growth & development | Imipenem - chemistry | Nanofibers - chemistry | Imipenem - administration & dosage | Cilastatin - administration & dosage | Cilastatin - chemistry | Chitosan - administration & dosage | Polyethylene Glycols - administration & dosage | Zinc Oxide - administration & dosage | Anti-Inflammatory Agents - chemistry | Chitosan - chemistry | Drug Liberation | Nanoparticles - administration & dosage | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Anti-Bacterial Agents - administration & dosage | Drug Combinations | Medical colleges | Polyethylene | Zinc oxide | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2012, Volume 161, Issue 3, pp. 735 - 745
The objective of the present study was to investigate the effect of polyarginine chain length on topical delivery of surface modified NLCs. Design of... 
Nanostructured lipid carriers (NLC) | Cell penetrating peptide (CPP) | Polyarginine peptide | Skin delivery | Allergic contact dermatitis (ACD) | DRUG-DELIVERY | CHITOSAN CROSS-LINKING | TRANSDERMAL DELIVERY | MEFLOQUINE HYDROCHLORIDE MICROPARTICLES | CELL-PENETRATING PEPTIDES | TACROLIMUS OINTMENT | CHEMISTRY, MULTIDISCIPLINARY | DERMAL DELIVERY | PHARMACOLOGY & PHARMACY | H-II MESOPHASES | SUBSTANCE-P | SPANTIDE-II | Nanoparticles - chemistry | Drug Carriers - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Drug Carriers - chemistry | Peptides - administration & dosage | Ketoprofen - chemistry | Allergens - administration & dosage | Lipids - chemistry | Rats, Hairless | Skin Absorption - drug effects | Substance P - analogs & derivatives | Oligopeptides - chemistry | Cell-Penetrating Peptides - chemistry | Dermatitis, Allergic Contact - drug therapy | Peptides - chemistry | Mice, Inbred C57BL | Ketoprofen - administration & dosage | Rats | Lipids - administration & dosage | Dinitrofluorobenzene - administration & dosage | Animals | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Mice | Nanoparticles - administration & dosage | Oligopeptides - administration & dosage | Cell-Penetrating Peptides - administration & dosage | Administration, Topical | Substance P - chemistry | Substance P - administration & dosage | Usage | Peptides | Dermatology | Analysis | Formulae, receipts, prescriptions | Dermatologic agents | Skin | Raman spectroscopy | Transdermal medication | Index Medicus | polyarginine peptide | cell penetrating peptide (CPP) | nanostructured lipid carriers (NLC) | allergic contact dermatitis (ACD)
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 12/2013, Volume 458, Issue 2, pp. 305 - 314
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2013, Volume 133, Issue 5, pp. 1231 - 1239
Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the... 
WATER-SOLUBLE CHITOSAN | ANTIBACTERIAL PROPERTIES | MICROSPHERES | ALPHA | ACNE-VULGARIS | RELEASE | MICROPARTICLES | NANOTECHNOLOGY | DELIVERY | DERMATOLOGY | Alginates - therapeutic use | Anti-Infective Agents - pharmacology | Humans | Hexuronic Acids - administration & dosage | Skin Diseases, Bacterial - drug therapy | Drug Delivery Systems | Feasibility Studies | Nanoparticles - therapeutic use | Chitosan - therapeutic use | Anti-Inflammatory Agents - therapeutic use | Chitosan - pharmacology | Anti-Inflammatory Agents - administration & dosage | Glucuronic Acid - administration & dosage | Keratinocytes - microbiology | Alginates - pharmacology | Benzoyl Peroxide - pharmacology | Cell Line | Benzoyl Peroxide - administration & dosage | Benzoyl Peroxide - therapeutic use | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Propionibacterium acnes - physiology | Cells, Cultured | Chitosan - administration & dosage | Acne Vulgaris - drug therapy | Anti-Infective Agents - therapeutic use | Glucuronic Acid - therapeutic use | Alginates - administration & dosage | Glucuronic Acid - pharmacology | Anti-Infective Agents - administration & dosage | Keratinocytes - drug effects | Propionibacterium acnes - ultrastructure | Keratinocytes - metabolism | Nanoparticles - administration & dosage | Propionibacterium acnes - drug effects | Administration, Topical | Hexuronic Acids - pharmacology | Hexuronic Acids - therapeutic use | Index Medicus | Acne | Antimicrobial | Inflammation | Chitosan | Nanoparticle | Skin infection
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 02/2013, Volume 83, Issue 2, pp. 174 - 183
This work describes the effect of polymeric microcarriers on the intra- nasal uptake of azolmitriptan for brain targeting. Moreover, the suitability of... 
Nasal administration | Microspheres | Brain targeting | Chitosan | Zolmitriptan | In vivo studies | MUCOADHESIVE MICROSPHERES | DELIVERY-SYSTEMS | CHITOSAN-GLUTAMATE | CEREBROSPINAL-FLUID | RAT MODEL | NASAL ABSORPTION | PHARMACOLOGY & PHARMACY | BIOADHESIVE FORMULATIONS | SUBMICRON EMULSION | HEALTHY-VOLUNTEERS | Polymers - administration & dosage | Chemistry, Pharmaceutical - methods | Hypromellose Derivatives - chemistry | Area Under Curve | Drug Carriers - administration & dosage | Oxazolidinones - administration & dosage | Drug Carriers - chemistry | Adhesives - chemistry | Oxazolidinones - chemistry | Adhesives - administration & dosage | Administration, Intranasal - methods | Swine | Nasal Mucosa - drug effects | Powders - administration & dosage | Tryptamines - chemistry | Chitosan - administration & dosage | Hypromellose Derivatives - administration & dosage | Permeability | Migraine Disorders - drug therapy | Brain - drug effects | Powders - chemistry | Glutamic Acid - administration & dosage | Animals | Chitosan - chemistry | Administration, Intravenous - methods | Glutamic Acid - chemistry | Tryptamines - administration & dosage | Glutamate | Index Medicus | Annan hälsovetenskap | Health Science | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Other Health Sciences | Hälsovetenskaper | Health Sciences
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 07/2016, Volume 233, pp. 181 - 190
Although significant progress has been achieved, effective oral delivery of protein drugs such as insulin by nanoparticle-based carrier systems still faces... 
Nanoparticles | Low molecular weight protamine | Mucoadhesion | Insulin | Oral delivery | Cell-penetrating peptide | MOLECULAR-WEIGHT PROTAMINE | PROTEIN DRUGS | DRUG-DELIVERY | CELL PENETRATING PEPTIDES | GASTROINTESTINAL MUCUS | CHEMISTRY, MULTIDISCIPLINARY | TRIMETHYL CHITOSAN CHLORIDE | INTESTINAL-ABSORPTION | IN-VITRO | PHARMACOLOGY & PHARMACY | PLGA NANOPARTICLES | CACO-2 CELLS | Diabetes Mellitus, Experimental - drug therapy | Intestinal Mucosa - metabolism | Nanoparticles - chemistry | Rats, Wistar | Humans | Intestinal Absorption - drug effects | Male | Diabetes Mellitus, Experimental - blood | Hypoglycemic Agents - administration & dosage | Protamines - administration & dosage | Diabetes Mellitus, Experimental - metabolism | Lactic Acid - administration & dosage | Cell-Penetrating Peptides - chemistry | Polyglycolic Acid - administration & dosage | Hypoglycemic Agents - therapeutic use | Insulin - pharmacology | Lactic Acid - chemistry | Protamines - chemistry | Blood Glucose - analysis | Administration, Oral | Adhesiveness | Chitosan - administration & dosage | Insulin - administration & dosage | Hypoglycemic Agents - chemistry | Intestinal Mucosa - chemistry | Hypoglycemic Agents - pharmacology | Animals | Chitosan - chemistry | Insulin - chemistry | Polyglycolic Acid - chemistry | Cell Line, Tumor | Drug Liberation | Nanoparticles - administration & dosage | Cell-Penetrating Peptides - administration & dosage | Insulin - therapeutic use | Permeability | Proteases | Gastrointestinal system | Index Medicus
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 12/2012, Volume 8, Issue 1, pp. 23 - 32
This study aimed to prepare nanoemulsions coated with alginate/chitosan for oral insulin delivery. Uncoated nanoemulsions were prepared by homogenization of a... 
Alginate | Chitosan | Insulin | Nanoemulsion | Oral delivery | alginate | chitosan | PROTEIN | insulin | LECITHIN-BASED MICROEMULSION | DRUG-DELIVERY | MULTIPLE EMULSION | NANOSCIENCE & NANOTECHNOLOGY | IONOTROPIC PRE-GELATION | DIABETIC-RATS | nanoemulsion | PEPTIDE | NANOPARTICLES | oral delivery | PHARMACOLOGY & PHARMACY | PARTICLE-SIZE | Diabetes Mellitus, Experimental - drug therapy | Nanoparticles - chemistry | Rats, Wistar | Drug Carriers - administration & dosage | Hexuronic Acids - administration & dosage | Male | Hexuronic Acids - pharmacokinetics | Drug Carriers - chemistry | Diabetes Mellitus, Experimental - blood | Emulsions - administration & dosage | Hypoglycemic Agents - administration & dosage | Glucuronic Acid - administration & dosage | Diabetes Mellitus, Experimental - metabolism | Glucuronic Acid - chemistry | Alginates - pharmacokinetics | Circular Dichroism | Hypoglycemic Agents - pharmacokinetics | Administration, Oral | Emulsions - chemistry | Drug Stability | Gastric Juice - metabolism | Chitosan - administration & dosage | Rats | Insulin - administration & dosage | Hypoglycemic Agents - chemistry | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Blood Glucose - drug effects | Particle Size | Alginates - administration & dosage | Animals | Chitosan - chemistry | Analysis of Variance | Chitosan - pharmacokinetics | Insulin - chemistry | Models, Biological | Alginates - chemistry | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Blood Glucose - metabolism | Emulsions - pharmacokinetics | Insulin - pharmacokinetics | Drugs | Drug delivery systems | Chitin | Research | Health aspects | Vehicles | Nanoemulsions | Diabetes | Rodents | Leakage | Spectroscopy | Particle size | Alginic acid | Diabetes mellitus | Oral administration | Polyelectrolytes | Phospholipids | Bioavailability | Coatings | Stress | Calcium chloride | Oil | C.D | nanotechnology | Gastric juice | Index Medicus | Original Research
Journal Article
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 06/2012, Volume 81, Issue 2, pp. 248 - 256
Schematic illustration of drug-loaded folic acid targeted nanoparticles of mixed lipid-shell and PLGA core (FLPNPs). A functional drug carrier comprised of... 
Drug delivery | PLGA | Nanoparticle | Paclitaxel | GYNECOLOGIC-ONCOLOGY-GROUP | BIODEGRADABLE MICROSPHERES | DRUG-DELIVERY | CONTROLLED-RELEASE | PHASE-II | LIPOSOMAL DAUNORUBICIN | CANCER | RECURRENT | ENDOTHELIAL-CELLS | METASTATIC NASOPHARYNGEAL CARCINOMA | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Nanoparticles - chemistry | Humans | Drug Carriers - administration & dosage | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Tissue Distribution | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Lipids - chemistry | Female | Paclitaxel - administration & dosage | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Lactic Acid - chemistry | Drug Compounding - methods | Chitosan - administration & dosage | Antineoplastic Agents, Phytogenic - chemistry | Lipids - administration & dosage | Mice, SCID | Chemistry, Pharmaceutical | Polyethylene Glycols - administration & dosage | Particle Size | Animals | Chitosan - chemistry | Polyglycolic Acid - chemistry | Cell Line, Tumor | Folic Acid - metabolism | Polymers - chemistry | Mice | Nanoparticles - administration & dosage | HeLa Cells | Drug Delivery Systems - methods | Drugs | Phosphates | Drug delivery systems | Leukemia | Liquid chromatography | Permeability | Chromatography | Folic acid | Vehicles | Nanoparticles | Lysine | Fluorescein | Dimethyl sulfoxide | Lymphomas | Index Medicus
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 2012, Volume 80, Issue 1, pp. 67 - 75
Response surface plots showing the effect of variations of formulation parameters (% alginate, chitosan (CSL) and calcium chloride and time of cross-linking...