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1. Full Text Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer
by Xu, J and Li, Y and Wang, F and Wang, X and Cheng, B and Ye, F and Xie, X and Zhou, C and Lu, W
Oncogene, ISSN 0950-9232, 02/2013, Volume 32, Issue 8, pp. 976 - 987
p-Chk1 | progression | miR-424 | Chk1 | cervical cancer | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Kinases - metabolism | Up-Regulation | Phosphorylation | Protein Kinases - genetics | Humans | Apoptosis - genetics | Uterine Cervical Neoplasms - pathology | Cell Movement - genetics | Matrix Metalloproteinase 9 - metabolism | Transfection | Uterine Cervical Neoplasms - metabolism | Female | G1 Phase - genetics | 3' Untranslated Regions | Cell Growth Processes - genetics | Protein Kinases - biosynthesis | Genes, Tumor Suppressor | Down-Regulation | MicroRNAs - biosynthesis | Uterine Cervical Neoplasms - genetics | S Phase - genetics | Disease Progression | Cell Line, Tumor | Checkpoint Kinase 1 | MicroRNAs - genetics | Development and progression | Genetic aspects | MicroRNA | Research | Analysis | Cervical cancer | Proteins | Gene expression | Medical prognosis | Index Medicus | Cell culture | CHK1 protein | Genomes | Malignancy | Matrix metalloproteinase | Tumor cell lines | Cervix | Lymph nodes | Metastases | Polymerase chain reaction | 3' Untranslated regions | Tumor suppressor genes | miRNA | Differentiation | Cell migration | Apoptosis | Tumors
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2. Full Text S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion
by Giannattasio, Michele and Branzei, Dana
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 07/2017, Volume 74, Issue 13, pp. 2361 - 2380
Rad53/CHK1/Cds1 | Chromosome fragility | Nucleases | Stalled replication forks | ATR/Mec1/Rad3 | Fork remodeling | Helicases | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | S Phase Cell Cycle Checkpoints | Chromosomes - metabolism | DNA Replication | Oligonucleotides - metabolism | Phenotype | DNA - metabolism | DNA synthesis | DNA replication | DNA binding proteins | Genomics | Analysis | DNA structure | Stresses | Regulations | Chromatin | Firing | Stability | Genomes | Phase transitions | Replication forks | Genomic instability | Fragmentation | DNA biosynthesis | Control | Depletion | Inhibitors | Reviews | Pathways | Cell cycle | Replication | Deoxyribonucleic acid--DNA | Reductase | Integrity | Index Medicus | Cds1 | Mec1 | Rad53 | CHK1 | Rad3 | Review | ATR
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3. Full Text Roles of Chk1 in cell biology and cancer therapy
by Zhang, Youwei and Hunter, Tony
International journal of cancer, ISSN 0020-7136, 03/2014, Volume 134, Issue 5, pp. 1013 - 1023
cancer therapy | cell cycle checkpoints | cancer | Chk1 | Life Sciences & Biomedicine | Oncology | Science & Technology | Phosphorylation | Protein Kinases - genetics | Cell Cycle | Humans | Protein Kinases - physiology | Protein Kinases - chemistry | Checkpoint Kinase 1 | DNA Replication | Drug Resistance, Neoplasm | Protein Conformation | Enzyme Activation | Neoplasms - drug therapy | Proteins | Antimitotic agents | Chemotherapy | Analysis | Genomics | Development and progression | Antineoplastic agents | Health aspects | Cells | Cancer | DNA damage | Cell cycle | Genomes | Kinases | Cancer therapies | Deoxyribonucleic acid--DNA | CHK1 protein | DNA repair | Protein kinase | Etiology | Tumor suppressor genes | Index Medicus
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4. Full Text Reality CHEK: Understanding the biology and clinical potential of CHK1
by Neizer-Ashun, Fiifi and Bhattacharya, Resham
Cancer letters, ISSN 0304-3835, 01/2021, Volume 497, pp. 202 - 211
CHK1 | DNA Damage response | Cell cycle | DNA replication | Tumor proteins | DNA repair | DNA damage | Cells | Index Medicus
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5. Full Text Targeting the ATR-CHK1 axis in cancer therapy
by Rundle, Stuart and Bradbury, Alice and Drew, Yvette and Curtin, Nicola J
Cancers, ISSN 2072-6694, 05/2017, Volume 9, Issue 5, p. 41
Protein-kinase-inhibitors | CHK1 | Cell cycle | DNA-damage | Chemotherapy-sensitising-agents | ATR | DNA-repair | Radiation-sensitising-agents | Life Sciences & Biomedicine | Oncology | Science & Technology | Ataxia telangiectasia mutated protein | Kinases | CHK1 protein | DNA damage | Cancer | Tumors | cell cycle | chemotherapy-sensitising-agents | protein-kinase-inhibitors | radiation-sensitising-agents
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6. Full Text Regulation of CHK1 by the Ubiquitin–Proteasome System
by Cartel, Maëlle and Didier, Christine
The FEBS journal, ISSN 1742-464X, 05/2020, Volume 287, Issue 10, pp. 1982 - 1984
CHK1 | ubiquitin | proteasome system | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Ubiquitin | Vertebrates | CHK1 protein | Cell cycle | Tumorigenesis | Genomes | Kinases | Ubiquitin-protein ligase | Huwe1 protein | Index Medicus | Life Sciences
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