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science & technology (351) 351
chlorambucil (305) 305
humans (297) 297
life sciences & biomedicine (297) 297
animals (239) 239
chlorambucil - pharmacology (210) 210
biological and medical sciences (159) 159
medical sciences (151) 151
chemistry (134) 134
chlorambucil - chemistry (130) 130
antineoplastic agents (126) 126
female (125) 125
male (123) 123
pharmacology. drug treatments (120) 120
pharmacology & pharmacy (114) 114
mice (104) 104
physical sciences (103) 103
biochemistry & molecular biology (97) 97
chlorambucil - therapeutic use (84) 84
cancer (79) 79
rats (69) 69
chlorambucil - metabolism (68) 68
chemotherapy (66) 66
cell line, tumor (64) 64
chlorambucil - administration & dosage (63) 63
drug delivery systems (57) 57
kinetics (57) 57
antineoplastic agents - pharmacology (56) 56
dose-response relationship, drug (56) 56
general aspects (56) 56
antineoplastic agents, alkylating - pharmacology (55) 55
oncology (54) 54
antineoplastic agents - chemistry (52) 52
cell survival - drug effects (52) 52
antineoplastic agents, alkylating - chemistry (50) 50
chemistry, medicinal (49) 49
chlorambucil - toxicity (49) 49
abridged index medicus (48) 48
chemistry, multidisciplinary (48) 48
toxicology (48) 48
structure-activity relationship (47) 47
drug resistance (45) 45
drugs (45) 45
middle aged (45) 45
alkylation (44) 44
research (44) 44
antimitotic agents (43) 43
chlorambucil - chemical synthesis (43) 43
chlorambucil - analogs & derivatives (42) 42
molecular structure (42) 42
time factors (41) 41
chemical phenomena (38) 38
tumor cells, cultured (38) 38
aged (36) 36
antineoplastic agents - chemical synthesis (34) 34
cytotoxicity (33) 33
cells, cultured (32) 32
genetics & heredity (32) 32
hydrogen-ion concentration (32) 32
leukemia, lymphocytic, chronic, b-cell - drug therapy (32) 32
tumors (32) 32
analysis (31) 31
apoptosis (29) 29
binding sites (29) 29
hematology (29) 29
cell proliferation - drug effects (28) 28
in vitro techniques (28) 28
molecular sequence data (28) 28
adult (27) 27
base sequence (27) 27
cell line (27) 27
hela cells (27) 27
alkylating agents - pharmacology (26) 26
chemistry, organic (26) 26
chlorambucil - pharmacokinetics (26) 26
drug screening assays, antitumor (26) 26
antineoplastic agents, alkylating - administration & dosage (25) 25
antineoplastic combined chemotherapy protocols - therapeutic use (25) 25
biotechnology & applied microbiology (25) 25
nitrogen mustard compounds - pharmacology (25) 25
alkylating agents (24) 24
apoptosis - drug effects (24) 24
cell division - drug effects (24) 24
dna (24) 24
dna - metabolism (24) 24
drug delivery (24) 24
nanoparticles (24) 24
dna damage (23) 23
hydrolysis (23) 23
technology (23) 23
vehicles (23) 23
leukemia, lymphocytic, chronic, b-cell - pathology (22) 22
chromatography, high pressure liquid (21) 21
dna - chemistry (21) 21
general pharmacology (21) 21
lymphocytes - drug effects (21) 21
melphalan - pharmacology (21) 21
care and treatment (20) 20
vidarabine - analogs & derivatives (20) 20
aged, 80 and over (19) 19
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