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Journal of Neuroscience, ISSN 0270-6474, 09/2004, Volume 24, Issue 36, pp. 7931 - 7938
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2006, Volume 314, Issue 5806, pp. 1788 - 1792
We report a signaling mechanism in rats between mother and fetus aimed at preparing fetal neurons for delivery. In immature neurons, γ-aminobutyric acid (GABA)... 
Brain | Neuroscience | Neurons | Pyramidal cells | Chlorides | Fetus | GABA antagonists | Reports | Hormones | Hippocampus | Oxytocin receptors | CELLS | SLICES | NEONATAL HIPPOCAMPUS | SEIZURES | SYNAPSES | MULTIDISCIPLINARY SCIENCES | NEURONS | VASOPRESSIN | EXCITATORY ACTIONS | CHANNELS | OSCILLATIONS | Parturition | Neural Inhibition | Oxytocin - pharmacology | Sodium Potassium Chloride Symporter Inhibitors | Rats, Wistar | Sodium-Potassium-Chloride Symporters - metabolism | Fetus - physiology | gamma-Aminobutyric Acid - physiology | Action Potentials | Chlorides - metabolism | Neurons - physiology | Female | Indoles - pharmacology | Benzamides - pharmacology | Animals, Newborn | Hippocampus - embryology | GABA-A Receptor Antagonists | Signal Transduction | Maternal-Fetal Exchange | Receptors, Oxytocin - antagonists & inhibitors | Oxytocin - physiology | Rats | Vasotocin - pharmacology | Fetal Hypoxia - physiopathology | Hippocampus - cytology | Vasotocin - analogs & derivatives | Pregnancy | GABA-A Receptor Agonists | Patch-Clamp Techniques | Animals | Solute Carrier Family 12, Member 2 | Receptors, GABA-A - physiology | Hippocampus - physiology | In Vitro Techniques | GABA | Fetal brain | Research | Oxytocin | Fetal monitoring | Analysis | Receptors, Oxytocin | Sodium-Potassium-Chloride Symporters | Receptors, GABA-A | Cellular Biology | Life Sciences | Vasotocin | Indoles | Fetal Hypoxia | gamma-Aminobutyric Acid | Benzamides
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 08/2008, Volume 295, Issue 2, pp. 556 - 567
We investigated which of the NaCl transporters are involved in the maintenance of salt-sensitive hypertension. Milan hypertensive (MHS) rats were studied 3 mo... 
Kidney-specific chloride channel | Type 3 sodium/hydrogen exchanger | Sodium-potassium 2 chloride cotransporter | Epithelial sodium channel | Pendrin | Sodium-chloride cotransporter | Aldosterone | NA-CL COTRANSPORTER | LOCALIZATION | PHYSIOLOGY | RAT | aldosterone | DISTAL TUBULE | kidney-specific chloride channel | type 3 sodium/hydrogen exchanger | BETA-SUBUNITS | BLOOD-PRESSURE | sodium-potassium 2 chloride cotransporter | TRANSPORT | UROLOGY & NEPHROLOGY | sodium-chloride cotransporter | epithelial sodium channel | pendrin | ADDUCIN ALPHA | EXPRESSION | MEDIATED REGULATION | Up-Regulation | Kidney Cortex - metabolism | Kidney Cortex - physiopathology | Chloride Channels - genetics | Epithelial Sodium Channels - metabolism | RNA, Messenger - metabolism | Rats, Inbred Strains | Sodium-Potassium-Chloride Symporters - metabolism | Sodium-Hydrogen Exchangers - metabolism | Sulfate Transporters | Aldosterone - metabolism | Hypertension - genetics | Disease Models, Animal | Sodium Chloride Symporters - metabolism | Sodium Chloride Symporters - genetics | Sodium Chloride, Dietary - adverse effects | Kidney Medulla - physiopathology | Rats | Hypertension - physiopathology | Hypertension - metabolism | Chloride Channels - metabolism | Chloride-Bicarbonate Antiporters - metabolism | Patch-Clamp Techniques | Solute Carrier Family 12, Member 1 | Animals | Kidney Medulla - metabolism | Sodium-Hydrogen Exchanger 3 | Index Medicus
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2018, Volume 379, Issue 17, pp. 1612 - 1620
This preclinical, phase 2 report shows that VX-445, a CFTR potentiator when administered with tezacaftor and ivacaftor, improved lung function and reduced... 
G551D MUTATION | MEDICINE, GENERAL & INTERNAL | TEZACAFTOR-IVACAFTOR | CFTR | Pyrazoles - therapeutic use | Forced Expiratory Volume - drug effects | Humans | Pyrrolidines - administration & dosage | Chloride Channel Agonists - therapeutic use | Male | Aminophenols - therapeutic use | Chloride Channel Agonists - adverse effects | Aminophenols - adverse effects | Pyrrolidines - pharmacology | Pyrrolidines - therapeutic use | Sweat - chemistry | Young Adult | Quinolones - adverse effects | Chlorides - metabolism | Quinolones - therapeutic use | Adult | Benzodioxoles - adverse effects | Female | Benzodioxoles - therapeutic use | Pyrazoles - pharmacology | Pyridines - therapeutic use | Pyridines - administration & dosage | Double-Blind Method | Genotype | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Chlorides - analysis | Pyrazoles - administration & dosage | Indoles - adverse effects | Cystic Fibrosis - genetics | Adolescent | Alleles | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Indoles - therapeutic use | Pyridines - pharmacology | Mutation | Cystic Fibrosis - drug therapy | Drug Combinations | Cystic fibrosis | Ivacaftor | Dosage and administration | Drug therapy | Statistical analysis | Writers | Epithelial cells | Chloride transport | Recovery of function | Patients | Design | Proteins | Genotype & phenotype | Chloride | Collaboration | Conductance | Cystic fibrosis transmembrane conductance regulator | Protein transport | Sweat | Pharmaceuticals
Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 5, p. e0196512
Journal Article