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Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 10/2013, Volume 379, Issue 1-2, pp. 62 - 73
Mitochondria are essential sites for steroid hormone biosynthesis. Mitochondria in the steroidogenic cells of the adrenal, gonad, placenta and brain contain... 
Cholesterol transport | Steroidogenesis | Steroidogenic acute regulatory protein | Cholesterol side chain cleavage | Vitamin D | Outer mitochondrial membrane | VITAMIN-D 1-ALPHA-HYDROXYLASE | CYTOCHROME P450(SCC) | CHAIN CLEAVAGE ENZYME | LIPOID ADRENAL-HYPERPLASIA | CHOLESTEROL-BINDING | ACUTE-REGULATORY-PROTEIN | LEYDIG TUMOR-CELLS | CELL BIOLOGY | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | ADRENODOXIN REDUCTASE | PERIPHERAL BENZODIAZEPINE-RECEPTOR | ENDOCRINOLOGY & METABOLISM | Mitochondria - enzymology | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Humans | Gonadal Steroid Hormones - biosynthesis | Voltage-Dependent Anion Channel 1 - metabolism | Mitochondria - metabolism | Cholesterol - metabolism | Phosphoproteins - metabolism | Mitochondrial Membranes - metabolism | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - metabolism | Adrenal Cortex Hormones - biosynthesis | Receptors, GABA - metabolism | Vitamin D - metabolism | Biological Transport - physiology | Membrane Proteins - metabolism | Mitochondrial Membranes - enzymology | Placental Hormones - biosynthesis | Adaptor Proteins, Signal Transducing - metabolism | Pregnenolone - biosynthesis | Enzymes | Physiological aspects | Calcifediol | Mitochondrial DNA | Alfacalcidol | Steroid hormones | Index Medicus | Proteins | Regulators | Mitochondria | Hormones | Kinases | Cholesterol | Steroids
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 25, pp. 10139 - 10143
In humans, the precursor to all steroid hormones, pregnenolone, is synthesized from cholesterol by an enzyme complex comprising adrenodoxin reductase (AdR),... 
Molecules | Enzymes | Oxygen | Active sites | Molecular interactions | Electron transfer | Cytochromes | Biochemistry | Cholesterols | Electrons | Hydroxysteroids | Fusion protein | Inner mitochondrial membrane | Ferredoxin-hemeprotein electron transfer | SITE | SIDE-CHAIN CLEAVAGE | CYTOCHROME P450SCC CYP11A1 | inner mitochondrial membrane | CHOLESTEROL | MECHANISM | MULTIDISCIPLINARY SCIENCES | ferredoxin-hemeprotein electron transfer | LYSINE RESIDUES | fusion protein | REDUCTASE-ADRENODOXIN COMPLEX | hydroxysteroids | F-G LOOP | BINDING | STEROIDOGENIC ELECTRON-TRANSPORT | Mitochondria - enzymology | Catalytic Domain | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Oxidation-Reduction | Cholesterol Side-Chain Cleavage Enzyme - chemistry | Humans | Adrenodoxin - metabolism | Models, Molecular | Mixed Function Oxygenases - metabolism | Cholesterol - metabolism | Static Electricity | Animals | Cattle | Protein Binding | Adrenodoxin - chemistry | Protein Conformation | Pregnenolone - biosynthesis | Proteins | Mitochondria | Research | Properties | Structure | Steroid hormones | Eukaryotes | Biosynthesis | Cholesterol | Index Medicus | Cytochrome | Conservation | cholesterol | Iron | Catalysis | steroid hormones | CATALYSIS | STEROID HORMONES | ELECTRON TRANSFER | HYDROXYPREGNENONE | PRECURSOR | BASIC BIOLOGICAL SCIENCES | SUBSTRATES | MEMBRANES | CRYSTAL STRUCTURE | IRON | CLEAVAGE | CYTOCHROMES | HEME | BIOSYNTHESIS | ENZYMES | GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE | ELECTROSTATICS | REACTION INTERMEDIATES | GEOMETRY | OXIDOREDUCTASES | Biological Sciences
Journal Article
Journal Article
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 09/2011, Volume 301, Issue 3, pp. 484 - 493
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 10, pp. 2666 - 2671
Journal Article