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Journal Article
American Journal of Psychiatry, ISSN 0002-953X, 08/2008, Volume 165, Issue 8, pp. 1040 - 1047
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2012, Volume 303, Issue 11, pp. 956 - 966
Activation of taste receptors (TAS2Rs) by bitter taste agonists has been reported to cause bronchodilation. The aim of this study was to extend the information... 
Bronchodilation | Prostaglandins | Airway smooth muscle | Asthma | ACTIVATION | PHYSIOLOGY | POTASSIUM CHANNELS | INDUCED BRONCHODILATION | airway smooth muscle | asthma | ANTAGONISM | RESPONSES | BK CHANNELS | TONE | RESPIRATORY SYSTEM | OBSTRUCTION | prostaglandins | bronchodilation | Large-Conductance Calcium-Activated Potassium Channels - metabolism | Respiratory Mucosa - drug effects | Receptors, G-Protein-Coupled - metabolism | Albuterol - pharmacology | Male | Trachea - drug effects | Large-Conductance Calcium-Activated Potassium Channels - antagonists & inhibitors | Trachea - metabolism | Receptors, G-Protein-Coupled - agonists | Chloroquine - pharmacology | Muscle, Smooth - drug effects | Large-Conductance Calcium-Activated Potassium Channels - physiology | Charybdotoxin - pharmacology | Trachea - physiology | Indoles - pharmacology | Muscle, Smooth - physiology | Cholinergic Agonists - pharmacology | Gene Expression | Guinea Pigs | Bronchodilator Agents - pharmacology | Indomethacin - pharmacology | Peptides - pharmacology | Carbachol - pharmacology | Animals | Muscle Contraction - drug effects | Receptors, G-Protein-Coupled - genetics | Muscle Relaxation - drug effects | In Vitro Techniques | Quaternary Ammonium Compounds - pharmacology | Physiological aspects | Taste | Genetic aspects | Research | Drug therapy | Trachea | Bronchodilator agents
Journal Article
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 03/2013, Volume 240, Issue 1, pp. 119 - 133
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 12/2012, Volume 224, Issue 4, pp. 489 - 499
Alterations in cost–benefit decision making accompany numerous neuropsychiatric conditions, including schizophrenia, attention deficit hyperactivity disorder,... 
Nicotinic | Neurosciences | Impulsivity | Perseveration | Biomedicine | Muscarinic | Risk | Delay discounting | Pharmacology/Toxicology | Psychiatry | Cholinergic | Probability discounting | YOUNG-ADULTS | ACETYLCHOLINE | PSYCHIATRY | FOOD-INTAKE | BEHAVIOR | SMOKING | REWARD | NEUROSCIENCES | SMOKERS | IMPULSIVE CHOICE | LOW-DOSE MECAMYLAMINE | PHARMACOLOGY & PHARMACY | AMPHETAMINE | Choice Behavior - drug effects | Nicotine - administration & dosage | Rats, Long-Evans | Decision Making - drug effects | Probability | Rats | Atropine - pharmacology | Male | Nicotine - pharmacology | Dose-Response Relationship, Drug | Muscarinic Antagonists - administration & dosage | Nicotinic Agonists - administration & dosage | Scopolamine Hydrobromide - pharmacology | Animals | Muscarinic Antagonists - pharmacology | Cost-Benefit Analysis | Scopolamine Hydrobromide - administration & dosage | Atropine - administration & dosage | Reward | Nicotinic Agonists - pharmacology | Decision-making | Economic aspects | Schizophrenia | Cost benefit analysis | Attention-deficit hyperactivity disorder | Drug addiction | Behavioral decision theory | Psychopharmacology | Benefit cost analysis | Scopolamine | Acetylcholine receptors (muscarinic) | Mental disorders | Decision making | Therapeutic applications | Attention deficit hyperactivity disorder | Data processing | Antagonists | mecamylamine | oxotremorine | Addiction | Etiology | Acetylcholine receptors | Atropine | Reinforcement | Acetylcholine receptors (nicotinic) | Cholinergic transmission | Nicotine
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2009, Volume 78, Issue 7, pp. 803 - 812
The novel alpha7 neuronal nicotinic receptor-selective agonist TC-5619 demonstrates efficacy in animal models of the positive and negative symptoms and... 
Alpha7 | Schizophrenia | Antipsychotic | Acetylcholine | Nicotinic receptor | Cholinergic | GATING DEFICITS | ALPHA-7-NICOTINIC ACETYLCHOLINE-RECEPTOR | ENHANCING PROPERTIES | PREPULSE INHIBITION | ALLOSTERIC MODULATOR | MEMORY | IN-VIVO | PHARMACOLOGY & PHARMACY | RAT-BRAIN | BINDING | HIPPOCAMPAL INTERNEURONS | Clozapine - therapeutic use | Schizophrenia - metabolism | Benzofurans - pharmacology | Cognition Disorders - metabolism | Male | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Schizophrenic Psychology | Clozapine - pharmacology | Quinuclidines - therapeutic use | Antipsychotic Agents - therapeutic use | Social Behavior | Exploratory Behavior - drug effects | Reflex, Startle - drug effects | Behavior, Animal - drug effects | Female | Neurons - metabolism | Nicotinic Agonists - pharmacology | Cognition Disorders - psychology | Promoter Regions, Genetic | Benzofurans - therapeutic use | Quinuclidines - pharmacology | Rats | Mice, Transgenic | Cognition Disorders - drug therapy | Maze Learning - drug effects | Nicotinic Agonists - therapeutic use | Rats, Sprague-Dawley | Tyrosine 3-Monooxygenase - genetics | Animals | Receptors, Nicotinic - physiology | Mice | Antipsychotic Agents - pharmacology | Schizophrenia - drug therapy | Receptor, Fibroblast Growth Factor, Type 1 - biosynthesis | alpha7 Nicotinic Acetylcholine Receptor | Models | Neurons | Analysis
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2008, Volume 117, Issue 2, pp. 232 - 243
Muscarinic acetylcholine receptors (mAChRs) are widely expressed in the CNS where they control a variety of neuronal functions. Due to their roles in a number... 
Parkinson's disease | mAChR | Schizophrenia | CNS | Drug dependence | Muscarinic receptors | Alzheimer's disease | AFFINITY AGONIST BINDING | ALZHEIMERS-DISEASE | schizophrenia | AMYLOID PRECURSOR PROTEIN | SUBSTANTIA-NIGRA | drug dependence | PEDUNCULOPONTINE TEGMENTAL NUCLEUS | muscarinic receptors | EXPERIMENTAL CHOLINERGIC DENERVATION | M-1 RECEPTOR | A-BETA | PHARMACOLOGY & PHARMACY | HAMSTER OVARY-M1 CELLS | NIGRA PARS COMPACTA | Central Nervous System Agents - therapeutic use | Schizophrenia - metabolism | Antiparkinson Agents - pharmacology | Central Nervous System - metabolism | Muscarinic Agonists - pharmacology | Humans | Muscarinic Agonists - therapeutic use | Receptor, Muscarinic M2 - drug effects | Receptors, Muscarinic - metabolism | Parkinson Disease - drug therapy | Muscarinic Antagonists - therapeutic use | Receptors, Muscarinic - drug effects | Receptor, Muscarinic M1 - drug effects | Muscarinic Antagonists - pharmacology | Parkinson Disease - metabolism | Substance-Related Disorders - metabolism | Receptor, Muscarinic M2 - metabolism | Alzheimer Disease - drug therapy | Receptor, Muscarinic M4 - metabolism | Animals | Receptor, Muscarinic M4 - drug effects | Alzheimer Disease - metabolism | Central Nervous System Agents - pharmacology | Central Nervous System - drug effects | Antipsychotic Agents - pharmacology | Schizophrenia - drug therapy | Substance-Related Disorders - drug therapy | Receptor, Muscarinic M1 - metabolism | Antipsychotic drugs | Antiparkinsonian agents
Journal Article