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Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 07/2019, Volume 62, Issue 9, pp. 604 - 607
A useful synthesis of (R)‐[N‐methyl‐3H]quinuclidinyl benzilate methiodide is described with the product characterized by thin‐layer chromatography (TLC),... 
tritium | muscarinic receptor | quinuclidinyl benzilate methiodide | tritium NMR | CHEMISTRY, ANALYTICAL | CHEMISTRY, MEDICINAL | RAT | QUINUCLIDINYL BENZILATE | BIOCHEMICAL RESEARCH METHODS | BINDING | Mass spectrometry | High performance liquid chromatography
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7386, pp. 547 - 551
Journal Article
Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 2/2017, Volume 31, Issue 2, pp. 192 - 203
Journal Article
NATURE STRUCTURAL & MOLECULAR BIOLOGY, ISSN 1545-9993, 11/2014, Volume 21, Issue 11, pp. 976 - 980
We determined the X-ray crystal structures of the extracellular domain (ECD) of the monomeric state of human neuronal alpha 9 nicotinic acetylcholine receptor... 
CHOLINERGIC-RECEPTOR | GATED ION-CHANNEL | CYS-LOOP RECEPTOR | BUNGAROTOXIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-RAY-STRUCTURE | RESOLUTION | ACETYLCHOLINE-RECEPTOR | CELL BIOLOGY | BIOPHYSICS | COCHLEAR HAIR-CELLS | LIGAND-BINDING DOMAIN | PHARMACOLOGICAL-PROPERTIES
Journal Article
EUROPEAN JOURNAL OF PHARMACOLOGY, ISSN 0014-2999, 07/2016, Volume 782, pp. 70 - 76
Identification of synthetic ligands selective for muscarinic receptor subtypes has been challenging due to the high sequence identity and structural homology... 
PROTEIN | ALZHEIMERS-DISEASE | SCHIZOPHRENIA | ALLOSTERIC MODULATION | Subtype selectivity | PCS1055 | TREMULOUS JAW MOVEMENTS | Muscarinic M-4 receptors | ACETYLCHOLINE-RECEPTORS | Competitive antagonists | CHOLINERGIC INTERNEURONS | PHARMACOLOGY | PHARMACOLOGY & PHARMACY | DYSFUNCTION | PARKINSONS-DISEASE
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2001, Volume 44, Issue 4, pp. 477 - 501
ATYPICAL ANTIPSYCHOTIC-DRUGS | IN-VIVO MICRODIALYSIS | CHEMISTRY, MEDICINAL | NITRIC-OXIDE SYNTHASE | POSITRON EMISSION TOMOGRAPHY | HIGH-AFFINITY ANTAGONIST | METABOTROPIC GLUTAMATE RECEPTORS | CENTRAL-NERVOUS-SYSTEM | EXCITOTOXIC HIPPOCAMPAL DAMAGE | DOPAMINE D-4 RECEPTOR | D-ASPARTATE RECEPTOR | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Excitatory Amino Acid Antagonists - therapeutic use | Schizophrenia - metabolism | Antipsychotic Agents - adverse effects | Humans | Receptors, Serotonin - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Cholinergic Agonists - therapeutic use | Cholinergic Agonists - adverse effects | Serotonin Antagonists - adverse effects | Antipsychotic Agents - therapeutic use | Receptors, Dopamine D2 - drug effects | Excitatory Amino Acid Antagonists - adverse effects | Cholinergic Agonists - pharmacology | Disease Models, Animal | Enzyme Inhibitors - adverse effects | Enzyme Inhibitors - pharmacology | Serotonin Antagonists - therapeutic use | Dopamine Antagonists - therapeutic use | Mice, Transgenic | Excitatory Amino Acid Antagonists - pharmacology | Serotonin Antagonists - pharmacology | Enzyme Inhibitors - therapeutic use | Receptor, Serotonin, 5-HT2A | Schizophrenia - etiology | Receptors, Neurotensin - agonists | Animals | Dopamine Antagonists - pharmacology | Receptors, Dopamine D4 | Dopamine Antagonists - adverse effects | Mice | Antipsychotic Agents - pharmacology | Schizophrenia - drug therapy | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Receptors, AMPA - antagonists & inhibitors
Journal Article