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1. Anticholinesterase pesticides
: metabolism, neurotoxicity, and epidemiology
by Satoh, Tetsuo and Gupta, Ramesh C
2010, 1. Aufl., ISBN 9780470410301, xviii, 625
Chemistry | SCIENCE | Industrial & Technical | Cholinesterase-inhibiting insecticides | Toxicology
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2. Full Text Phytochemical contents and enzyme inhibitory and antioxidant properties of Anethum graveolens L. (dill) samples cultivated under organic and conventional agricultural conditions
by Erdogan Orhan, Ilkay and Senol, F. Sezer and Ozturk, Nilgun and Celik, Sadiye Ayse and Pulur, Aysen and Kan, Yuksel
Food and chemical toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 96 - 103
Enzyme inhibition | Anethum graveolens | Oil | Dill | Phenolic acid | Antioxidant activity | Food Science & Technology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Oils, Volatile - chemistry | Plant Extracts - pharmacology | Solvents - chemistry | Anethum graveolens - chemistry | Antioxidants - metabolism | Oils, Volatile - pharmacology | Iron Chelating Agents - metabolism | Butyrylcholinesterase - chemistry | Cholinesterase Inhibitors - metabolism | Butyrylcholinesterase - metabolism | Cholinesterase Inhibitors - isolation & purification | Fish Proteins - antagonists & inhibitors | Enzyme Inhibitors - metabolism | Fruit - chemistry | Enzyme Inhibitors - pharmacology | Fish Proteins - metabolism | Cholinesterase Inhibitors - analysis | Electrophorus | Enzyme Inhibitors - analysis | Food, Organic - analysis | Plant Extracts - isolation & purification | Acetylcholinesterase - chemistry | Enzyme Inhibitors - isolation & purification | Iron Chelating Agents - analysis | Iron Chelating Agents - isolation & purification | Fruit - growth & development | Cholinesterase Inhibitors - pharmacology | Antioxidants - isolation & purification | Monoterpenes - metabolism | Monoterpenes - analysis | Acetylcholinesterase - metabolism | Plant Extracts - chemistry | Anethum graveolens - metabolism | Depsides - analysis | Fungal Proteins - antagonists & inhibitors | Monophenol Monooxygenase - antagonists & inhibitors | Monophenol Monooxygenase - metabolism | Cinnamates - metabolism | Antioxidants - analysis | Fruit - metabolism | Depsides - metabolism | Nitric Oxide - antagonists & inhibitors | Antioxidants - pharmacology | Oils, Volatile - isolation & purification | Drug Discovery | Animals | Iron Chelating Agents - pharmacology | Horses | Cinnamates - analysis | Anethum graveolens - growth & development | Fungal Proteins - metabolism | Antioxidants | Monounsaturated fatty acids | Analysis | Index Medicus
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3. Full Text Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease
by Wang, Li and Esteban, Gerard and Ojima, Masaki and Bautista-Aguilera, Oscar M and Inokuchi, Tsutomu and Moraleda, Ignacio and Iriepa, Isabel and Samadi, Abdelouahid and Youdim, Moussa B.H and Romero, Alejandro and Soriano, Elena and Herrero, Raquel and Fernández Fernández, Ana Patricia and Ricardo-Martínez-Murillo and Marco-Contelles, José and Unzeta, Mercedes
European journal of medicinal chemistry, ISSN 0223-5234, 06/2014, Volume 80, pp. 543 - 561
Multifunctional drugs | ChE and MAO inhibitors | Fe/Cu/Zn chelators | Alzheimer's disease | In vivo scopolamine-induced long-term memory deficit | Donepezil + Propargylamine + 8-Hydroxyquinoline hybrids | In vivo scopolamine-induced long-term memory deficit | Memory - drug effects | Cholinesterase Inhibitors - toxicity | Hydroxyquinolines - chemistry | Humans | Male | Pargyline - analogs & derivatives | Cholinesterase Inhibitors - metabolism | Chelating Agents - therapeutic use | Indans - chemistry | Monoamine Oxidase Inhibitors - therapeutic use | Propylamines - chemistry | Monoamine Oxidase Inhibitors - pharmacology | Piperidines - chemistry | Pargyline - chemistry | Alzheimer Disease - drug therapy | Rats | Acetylcholinesterase - chemistry | Chelating Agents - pharmacology | Hep G2 Cells | Monoamine Oxidase Inhibitors - toxicity | Animals | Chelating Agents - toxicity | Cholinesterase Inhibitors - pharmacology | Monoamine Oxidase Inhibitors - metabolism | Molecular Docking Simulation | Chelating Agents - metabolism | Cholinesterase Inhibitors - therapeutic use | Acetylcholinesterase - metabolism | Monoamine Oxidase - metabolism | Animal experimentation | Enzyme inhibitors | Analysis | Quinoline | Enantiomers | Drug therapy | Index Medicus
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4. Full Text The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products
by Bayrak, Cetin and Taslimi, Parham and Karaman, Halide Sedef and Gulcin, Ilhami and Menzek, Abdullah
Bioorganic chemistry, ISSN 0045-2068, 04/2019, Volume 85, pp. 128 - 139
Enzyme inhibition | Carbonic anhydrase | Acetylcholinesterase | Bromination | Bromophenol | Molecular docking | Bromobenzenes - chemical synthesis | Cholinesterase Inhibitors - pharmacokinetics | Carbonic Anhydrase Inhibitors - pharmacokinetics | Cholinergic Antagonists - chemical synthesis | Biological Products - pharmacokinetics | Phenols - chemical synthesis | Humans | Carbonic Anhydrase II - metabolism | Cholinesterase Inhibitors - chemical synthesis | Carbonic Anhydrase I - metabolism | Butyrylcholinesterase - chemistry | Cholinesterase Inhibitors - metabolism | Butyrylcholinesterase - metabolism | Cholinergic Antagonists - pharmacokinetics | Bromobenzenes - metabolism | Carbonic Anhydrase Inhibitors - chemical synthesis | Acetylcholinesterase - chemistry | Carbonic Anhydrase I - chemistry | Phenols - metabolism | Bromobenzenes - pharmacokinetics | Cholinergic Antagonists - metabolism | Biological Products - chemical synthesis | Phenols - pharmacokinetics | Biological Products - metabolism | Protein Binding | Molecular Docking Simulation | Carbonic Anhydrase Inhibitors - metabolism | Acetylcholinesterase - metabolism | Carbonic Anhydrase II - chemistry | Hydroxides | Isoenzymes | Benzene | Resveratrol | Index Medicus
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5. Full Text Accumulation, tissue distribution, and biochemical effects of polystyrene microplastics in the freshwater fish red tilapia (Oreochromis niloticus)
by Ding, Jiannan and Zhang, Shanshan and Razanajatovo, Roger Mamitiana and Zou, Hua and Zhu, Wenbin
Environmental pollution (1987), ISSN 0269-7491, 07/2018, Volume 238, pp. 1 - 9
Biomarker | Red tilapia | Freshwater | Polystyrene microplastics | Accumulation | Environmental Sciences & Ecology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Malondialdehyde - metabolism | Cholinesterase Inhibitors - toxicity | Polystyrenes - metabolism | Antioxidants - metabolism | Liver - metabolism | Cholinesterase Inhibitors - analysis | Gills - metabolism | Polystyrenes - toxicity | Cytochrome P-450 CYP1A1 - metabolism | Polystyrenes - analysis | Water Pollutants, Chemical - analysis | Gastrointestinal Tract - metabolism | Brain - metabolism | Tissue Distribution | Water Pollutants, Chemical - metabolism | Animals | Water Pollutants, Chemical - toxicity | Cholinesterase Inhibitors - metabolism | Fresh Water | Tilapia - metabolism | Acetylcholinesterase - metabolism | Superoxide Dismutase - metabolism | Antioxidants | Fishes | Analysis | Liver | Cytochrome P-450 | Physiological aspects | Fish as food | Polystyrene | Index Medicus
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6. Full Text A review on cholinesterase inhibitors for Alzheimer’s disease
by Anand, Preet and Singh, Baldev
Archives of pharmacal research, ISSN 0253-6269, 4/2013, Volume 36, Issue 4, pp. 375 - 399
Alzheimer’s disease | Pharmacy | Donepezil | Pharmacology/Toxicology | Acetylcholinesterase | Flavonoid | Tacrine | Alzheimer's disease | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Alzheimer Disease - physiopathology | Brain - physiopathology | Humans | Cholinesterase Inhibitors - chemistry | Alzheimer Disease - drug therapy | Brain - enzymology | Nootropic Agents - therapeutic use | Structure-Activity Relationship | Alzheimer Disease - enzymology | Cognition - drug effects | Nootropic Agents - chemistry | Brain - drug effects | Plaque, Amyloid | Animals | Amyloid beta-Peptides - metabolism | Molecular Structure | Cholinesterases - metabolism | Cholinesterase Inhibitors - therapeutic use | Alzheimer Disease - psychology | Acetylcholine | Heterocyclic compounds | Galanthamine | Amyloid beta-protein | Target marketing | Index Medicus | 약학
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7. Full Text Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer’s disease
by Xu, Rui and Xiao, Ganyuan and Li, Yan and Liu, Hongyan and Song, Qing and Zhang, Xiaoyu and Yang, Ziyi and Zheng, Yunxiaozhu and Tan, Zhenghuai and Deng, Yong
Bioorganic & medicinal chemistry, ISSN 0968-0896, 05/2018, Volume 26, Issue 8, pp. 1885 - 1895
Benzo[d]isothiazol-3(2H)-one derivatives | Acetylcholinesterase inhibitors | Aβ aggregation inhibitors | Monoamine oxidase inhibitors | Multifunctional agents | Alzheimer’s disease | Alzheimer's disease | Antioxidants - chemistry | Antioxidants - metabolism | Humans | Cholinesterase Inhibitors - chemistry | Structure-Activity Relationship | Monoamine Oxidase - genetics | Alzheimer Disease - pathology | Benzylamines - metabolism | Monoamine Oxidase - chemistry | Cholinesterase Inhibitors - metabolism | Amyloid beta-Peptides - metabolism | Drug Design | Protein Aggregates - drug effects | Monoamine Oxidase Inhibitors - therapeutic use | Recombinant Proteins - metabolism | Permeability - drug effects | Alzheimer Disease - drug therapy | Recombinant Proteins - chemistry | Acetylcholinesterase - chemistry | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Benzylamines - chemistry | Monoamine Oxidase Inhibitors - metabolism | Thiazoles - chemistry | Monoamine Oxidase Inhibitors - chemistry | Amyloid beta-Peptides - chemistry | Kinetics | Cholinesterase Inhibitors - therapeutic use | Acetylcholinesterase - metabolism | Monoamine Oxidase - metabolism | Index Medicus
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8. Full Text Synthesis and biological evaluation of a new series of ebselen derivatives as glutathione peroxidase (GPx) mimics and cholinesterase inhibitors against Alzheimer’s disease
by Luo, Zonghua and Liang, Liang and Sheng, Jianfei and Pang, Yanqing and Li, Jianheng and Huang, Ling and Li, Xingshu
Bioorganic & medicinal chemistry, ISSN 0968-0896, 02/2014, Volume 22, Issue 4, pp. 1355 - 1361
Alzheimer’s disease | GPx mimics | Cholinesterase inhibitors | Alzheimer's disease | Biocompatible Materials - metabolism | Organoselenium Compounds - chemical synthesis | Antioxidants - metabolism | Humans | Azoles - metabolism | Azoles - therapeutic use | Cholinesterase Inhibitors - chemical synthesis | Organoselenium Compounds - chemistry | Biocompatible Materials - chemical synthesis | Butyrylcholinesterase - chemistry | Cholinesterase Inhibitors - metabolism | Glutathione Peroxidase - chemistry | Butyrylcholinesterase - metabolism | Organoselenium Compounds - therapeutic use | Glutathione Peroxidase - metabolism | Alzheimer Disease - drug therapy | Acetylcholinesterase - chemistry | Antioxidants - chemical synthesis | Azoles - chemical synthesis | Azoles - chemistry | Antioxidants - therapeutic use | Protein Binding | Biocompatible Materials - therapeutic use | Cholinesterase Inhibitors - therapeutic use | Acetylcholinesterase - metabolism | Organoselenium Compounds - metabolism | Peroxidase | Analysis | Amyloid beta-protein | Index Medicus
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9. Full Text Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity
by Ozmen Ozgun, Dilan and Gul, Halise Inci and Yamali, Cem and Sakagami, Hiroshi and Gulcin, Ilhami and Sukuroglu, Murat and Supuran, Claudiu T
Bioorganic chemistry, ISSN 0045-2068, 03/2019, Volume 84, pp. 511 - 517
Cytotoxicity | Sulfonamide | Carbonic anhydrase | Acetylcholinesterase | Pyrazoline | Cell Survival - drug effects | Sulfonamides - chemistry | Humans | Carbonic Anhydrase II - metabolism | Carbonic Anhydrase Inhibitors - chemical synthesis | Cholinesterase Inhibitors - chemical synthesis | Structure-Activity Relationship | Acetylcholinesterase - chemistry | Carbonic Anhydrase Inhibitors - pharmacology | Carbonic Anhydrase I - metabolism | Sulfonamides - pharmacology | Carbonic Anhydrase II - antagonists & inhibitors | Pyrazoles - chemistry | Cholinesterase Inhibitors - metabolism | Cholinesterase Inhibitors - pharmacology | Carbonic Anhydrase I - antagonists & inhibitors | Sulfonamides - metabolism | Cell Line, Tumor | Carbonic Anhydrase Inhibitors - metabolism | Acetylcholinesterase - metabolism | Isoenzymes | Sulfonamides | Enzyme inhibitors | Index Medicus
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10. Full Text Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease
by Sang, Zhipei and Pan, Wanli and Wang, Keren and Ma, Qinge and Yu, Lintao and Liu, Wenmin
Bioorganic & medicinal chemistry, ISSN 0968-0896, 06/2017, Volume 25, Issue 12, pp. 3006 - 3017
MAO-B inhibitor | BuChE inhibitor | Alzheimer’s disease | 3,4-Dihydro-2(1H)-quinoline-O-alkylamines | Blood-brain barrier | MAO-A inhibitor | AChE inhibitor | Alzheimer's disease | Monoamine Oxidase Inhibitors - pharmacology | Cholinesterase Inhibitors - pharmacokinetics | Humans | Quinolines - chemistry | Cholinesterase Inhibitors - chemistry | Alzheimer Disease - drug therapy | Electrophorus | Cholinesterase Inhibitors - chemical synthesis | Alzheimer Disease - enzymology | Monoamine Oxidase Inhibitors - chemical synthesis | Quinolines - pharmacology | Blood-Brain Barrier - metabolism | Monoamine Oxidase Inhibitors - pharmacokinetics | Quinolines - chemical synthesis | Quinolines - pharmacokinetics | Animals | Cholinesterase Inhibitors - pharmacology | Butyrylcholinesterase - metabolism | Swine | Drug Design | Monoamine Oxidase Inhibitors - chemistry | Acetylcholinesterase - metabolism | Monoamine Oxidase - metabolism | Oxidases | Alkaloids | Enzyme inhibitors | Surface active agents | Analysis | Resveratrol | Quinoline | Acetylcholine | Drug therapy | High performance liquid chromatography | Index Medicus
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11. Full Text Discovery of potent carbonic anhydrase and acetylcholinesterase inhibitors: 2-aminoindan β-lactam derivatives
by Genç, Hayriye and Kalin, Ramazan and Köksal, Zeynep and Sadeghian, Nastaran and Kocyigit, Umit M and Zengin, Mustafa and Gülçin, İlhami and Özdemir, Hasan
International journal of molecular sciences, ISSN 1661-6596, 10/2016, Volume 17, Issue 10, pp. 1736 - 1736
Enzyme inhibitionenzyme purification | Carbonic anhydrase | 2-azetidinone | Acetylcholinesterase | β-lactam | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Indans - chemistry | Carbonic Anhydrase Inhibitors - chemistry | Humans | Cholinesterase Inhibitors - chemistry | Neurotransmitter Agents - metabolism | Acetylcholine - metabolism | Azetidines - chemistry | beta-Lactams - chemistry | Acetylcholinesterase - metabolism | Carbonic Anhydrases - metabolism | carbonic anhydrase | acetylcholinesterase | enzyme purification | enzyme inhibition
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