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Chemical Science, ISSN 2041-6520, 11/2013, Volume 4, Issue 11, pp. 4137 - 4145
The number of people suffering from Alzheimer's disease (AD) is expected to increase dramatically in the coming decades. Currently, acetylcholinesterase... 
PERIPHERAL SITE | TACRINE HYBRIDS | PEPTIDES | MULTIFUNCTIONAL AGENTS | ALZHEIMERS-DISEASE | CHOLINESTERASE ACTIVITY | ANTIOXIDANT | COORDINATION | PRECURSOR PROTEIN | BINDING | CHEMISTRY, MULTIDISCIPLINARY | Retarding | Inhibitors | Aggregates | Chelation | Biochemistry | Inhibition | Assembly | Modulators
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2012, Volume 20, Issue 21, pp. 6513 - 6522
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 03/2009, Volume 108, Issue 5, pp. 1116 - 1125
Acetylcholinesterase inhibitors (AChE‐inhibitors) are used for the treatment of Alzheimer’s disease. Recently, the AChE‐inhibitor donepezil was found to have... 
donepezil | amyloid‐β | glycogen synthase kinase‐3 | nicotinic acetylcholine receptors | neuroprotection | phosphoinositide 3 kinase | Neuroprotection | Amyloid-β | Glycogen synthase kinase-3 | Donepezil | Nicotinic acetylcholine receptors | Phosphoinositide 3 kinase | SURVIVAL | MEDIATED NEUROPROTECTION | ALZHEIMERS-DISEASE | PHOSPHATIDYLINOSITOL 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAT CORTICAL-NEURONS | GLYCOGEN-SYNTHASE KINASE-3 | TAU-PHOSPHORYLATION | NEUROSCIENCES | amyloid-beta | glycogen synthase kinase-3 | EXTRACELLULAR ACETYLCHOLINE | NICOTINIC ACETYLCHOLINE-RECEPTOR | HYDROCHLORIDE E2020 | Apoptosis - drug effects | Embryo, Mammalian | Peptide Fragments - toxicity | Nicotinic Antagonists - pharmacology | Cerebral Cortex - cytology | Sincalide - metabolism | Nicotine - pharmacology | Dose-Response Relationship, Drug | Neuroprotective Agents - pharmacology | Piperidines - pharmacology | Mecamylamine - pharmacology | Neurons - physiology | Indoles | Phosphorylation - drug effects | Chromones - pharmacology | Neurons - drug effects | Nicotinic Agonists - pharmacology | Amyloid beta-Peptides - toxicity | Cell Survival | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cells, Cultured | Morpholines - pharmacology | Rats | Glycogen Synthase Kinase 3 - metabolism | Rats, Sprague-Dawley | Serine - metabolism | Animals | Analysis of Variance | Cholinesterase Inhibitors - pharmacology | Indans - pharmacology | Index Medicus
Journal Article
Journal Article
CURRENT PHARMACEUTICAL DESIGN, ISSN 1381-6128, 2019, Volume 25, Issue 18, pp. 2108 - 2112
Background: The inhibition of cholinesterase enzymes is one of the promising strategies to manage several neurological disorders that include Alzheimer's... 
cholinesterase enzymes | DRUG POSIPHEN | Acetylcholine esterase | molecular docking | phenserine | ALZHEIMERS-DISEASE | inhibition | PHARMACOLOGY & PHARMACY | AMYLOID PRECURSOR PROTEIN | kinetics | BETA PEPTIDE
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Journal Article
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