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2010, 1. Aufl., ISBN 9780470410301, xviii, 625
"This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism,... 
Cholinesterase-inhibiting insecticides | Toxicology | Chemistry | SCIENCE | Industrial & Technical
Book
Journal of Medicinal Chemistry, ISSN 0022-2623, 2/2008, Volume 51, Issue 3, pp. 347 - 372
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2009, Volume 52, Issue 9, pp. 2724 - 2732
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2013, Volume 56, Issue 22, pp. 9089 - 9099
A novel series of compounds obtained by fusing the cholinesterase inhibitor donepezil and the antioxidant ebselen were designed as multi-target-directed... 
MAMMALIAN THIOREDOXIN | CHEMISTRY, MEDICINAL | ACETYLCHOLINESTERASE | PEROXYNITRITE | DIPHENYL DISELENIDE | AMYLOID-BETA-PEPTIDES | ORGANOSELENIUM COMPOUNDS | HUMAN HEALTH | NITRIC-OXIDE | THIOREDOXIN REDUCTASE | BIOLOGICAL ASSESSMENT | Cholinesterase Inhibitors - toxicity | Organoselenium Compounds - chemical synthesis | Humans | Azoles - metabolism | Cholinesterase Inhibitors - chemical synthesis | Toxicity Tests, Acute | Molecular Targeted Therapy | Organoselenium Compounds - pharmacology | Cholinesterase Inhibitors - metabolism | Piperidines - pharmacology | Thioredoxin-Disulfide Reductase - metabolism | Butyrylcholinesterase - metabolism | Azoles - toxicity | Glutathione Peroxidase - metabolism | Piperidines - toxicity | Chemistry Techniques, Synthetic | Protein Structure, Secondary | Piperidines - metabolism | Indans - metabolism | Alzheimer Disease - drug therapy | Electrophorus | Acetylcholinesterase - chemistry | Azoles - chemical synthesis | Azoles - pharmacology | Piperidines - chemical synthesis | Organoselenium Compounds - toxicity | Peptide Fragments - chemistry | Animals | Cholinesterase Inhibitors - pharmacology | Peroxynitrous Acid - metabolism | Indans - toxicity | Indans - chemical synthesis | Ligands | Mice | Molecular Docking Simulation | Amyloid beta-Peptides - chemistry | Kinetics | Acetylcholinesterase - metabolism | Organoselenium Compounds - metabolism | Protein Multimerization - drug effects | Indans - pharmacology | Index Medicus
Journal Article
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 96 - 103
Inhibitory effect of the -hexane, dichloromethane, ethyl acetate, and ethanol extracts from L. (dill) cultivated under organic (AG-O) and conventional (AG-C)... 
Enzyme inhibition | Anethum graveolens | Oil | Dill | Phenolic acid | Antioxidant activity | CHOLINESTERASE | BUTYRYLCHOLINESTERASE | ESSENTIAL OILS | TURKEY | FOOD SCIENCE & TECHNOLOGY | IN-VITRO | ACETYLCHOLINESTERASE | PLANTS | TOXICOLOGY | VEGETABLES | EXTRACTS | CONSTITUENTS | Oils, Volatile - chemistry | Plant Extracts - pharmacology | Solvents - chemistry | Anethum graveolens - chemistry | Antioxidants - metabolism | Oils, Volatile - pharmacology | Iron Chelating Agents - metabolism | Butyrylcholinesterase - chemistry | Cholinesterase Inhibitors - metabolism | Butyrylcholinesterase - metabolism | Cholinesterase Inhibitors - isolation & purification | Fish Proteins - antagonists & inhibitors | Enzyme Inhibitors - metabolism | Fruit - chemistry | Enzyme Inhibitors - pharmacology | Fish Proteins - metabolism | Cholinesterase Inhibitors - analysis | Electrophorus | Enzyme Inhibitors - analysis | Food, Organic - analysis | Plant Extracts - isolation & purification | Acetylcholinesterase - chemistry | Enzyme Inhibitors - isolation & purification | Iron Chelating Agents - analysis | Iron Chelating Agents - isolation & purification | Fruit - growth & development | Cholinesterase Inhibitors - pharmacology | Antioxidants - isolation & purification | Monoterpenes - metabolism | Monoterpenes - analysis | Acetylcholinesterase - metabolism | Plant Extracts - chemistry | Anethum graveolens - metabolism | Depsides - analysis | Fungal Proteins - antagonists & inhibitors | Monophenol Monooxygenase - antagonists & inhibitors | Monophenol Monooxygenase - metabolism | Cinnamates - metabolism | Antioxidants - analysis | Fruit - metabolism | Depsides - metabolism | Nitric Oxide - antagonists & inhibitors | Antioxidants - pharmacology | Oils, Volatile - isolation & purification | Drug Discovery | Animals | Iron Chelating Agents - pharmacology | Horses | Cinnamates - analysis | Anethum graveolens - growth & development | Fungal Proteins - metabolism | Antioxidants | Monounsaturated fatty acids | Analysis | Index Medicus
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2017, Volume 337, pp. 67 - 75
The prevalence of obesity is increasing at an alarming rate in the United States with 36.5% of adults being classified as obese. Compared to normal... 
Chlorpyrifos | Organophosphate | Endocannabinoid | Acetylcholinesterase | Carboxylesterase | High-fat diet | TRIACYLGLYCEROL HYDROLASE | PARAOXONASE-1 RESPONSE | NATIONAL-HEALTH | PERSISTENT ORGANIC POLLUTANTS | RAT-LIVER MICROSOMES | NONDIABETIC ADULTS | SERUM CONCENTRATIONS | DECREASES BLOOD-LIPIDS | INSULIN-RESISTANCE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | HEPATIC STEATOSIS | Endocannabinoids - metabolism | Activation, Metabolic | Cholinesterase Inhibitors - toxicity | Liver - enzymology | Male | Obesity - blood | Chlorpyrifos - metabolism | Monoacylglycerol Lipases - metabolism | Arachidonic Acids - metabolism | Cholinesterase Inhibitors - metabolism | Liver - drug effects | Diet, High-Fat | Erythrocytes - enzymology | Hepatocytes - drug effects | Disease Models, Animal | Amidohydrolases - metabolism | Mice, Inbred C57BL | Cells, Cultured | Glycerides - metabolism | Polyunsaturated Alkamides - metabolism | Rats, Sprague-Dawley | GPI-Linked Proteins - metabolism | Erythrocytes - drug effects | Obesity - metabolism | Hydrolysis | Phenotype | Animals | Insecticides - metabolism | Chlorpyrifos - toxicity | Obesity - enzymology | Insecticides - toxicity | Acetylcholinesterase - metabolism | Carboxylic Ester Hydrolases - metabolism | Hepatocytes - enzymology | Obesity | Enzyme inhibitors | Analysis | Insecticides | Mice | Xenobiotics | Fatty acids | Index Medicus
Journal Article
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 04/2017, Volume 138, pp. 154 - 162
Journal Article
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 06/2016, Volume 128, pp. 21 - 29
Journal Article
Ecotoxicology, ISSN 0963-9292, 2/2008, Volume 17, Issue 2, pp. 93 - 101
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2009, Volume 623, Issue 1, pp. 14 - 21
We have recently demonstrated that bis(7)-Cognitin, a promising multifunctional anti-Alzheimer s dimer, can remarkably reduce the generation of amyloid β... 
Bis-Cognitin | Amyloid β peptide | α-Secretase | Protein kinase C | BACE-1 | BETA-SECRETASE | INDUCED NEURONAL APOPTOSIS | D-ASPARTATE RECEPTORS | AMYLOID-PRECURSOR-PROTEIN | HUPERZINE-A | alpha-Secretase | PKC ACTIVATION | DISEASE | PHARMACOLOGY & PHARMACY | Amyloid beta peptide | MULTIPLE-TARGETS | BIS-TACRINE | ACETYLCHOLINESTERASE INHIBITORS | Enzyme Activators - pharmacology | Amyloid Precursor Protein Secretases - genetics | AMP-Activated Protein Kinases - metabolism | Humans | Enzyme Activators - metabolism | Receptors, Muscarinic - metabolism | Aspartic Acid Endopeptidases - genetics | Dose-Response Relationship, Drug | Tacrine - pharmacology | Protein Isoforms - metabolism | Cholinesterase Inhibitors - metabolism | Protein Kinase C - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Phorbol Esters - pharmacology | Neurons - metabolism | Neurons - drug effects | Tacrine - analogs & derivatives | Muscarinic Antagonists - metabolism | Receptors, Muscarinic - genetics | Tacrine - metabolism | Peptide Fragments - metabolism | Cells, Cultured | Mutant Proteins - genetics | Alzheimer Disease - drug therapy | Rats | Mutant Proteins - metabolism | Protein Kinase C - antagonists & inhibitors | Amyloid Precursor Protein Secretases - metabolism | Phorbol Esters - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Cholinesterase Inhibitors - pharmacology | Aspartic Acid Endopeptidases - metabolism | Neurons - enzymology | Cell Line, Tumor | Mice | Protein Isoforms - genetics
Journal Article