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Journal of Cellular Physiology, ISSN 0021-9541, 07/2006, Volume 208, Issue 1, pp. 87 - 96
Canonical Wnt signaling (β‐catenin/TCF) has emerged as a key regulator of skeletogenesis. In this study, chondrogenesis is examined in a mouse model in which... 
ENDOCHONDRAL OSSIFICATION | IN-VITRO | PHYSIOLOGY | TGF-BETA | BONE-FORMATION | GENE-EXPRESSION | GROWTH-PLATE | INDIAN HEDGEHOG | BETA-CATENIN | CARTILAGE DEVELOPMENT | N-CADHERIN | CELL BIOLOGY | Growth Plate - pathology | Immunohistochemistry | Intercellular Signaling Peptides and Proteins - analysis | Chondrocytes - chemistry | Osteogenesis - physiology | Bone Morphogenetic Proteins - physiology | Fibroblasts - physiology | Collagen Type II - analysis | Core Binding Factor Alpha 1 Subunit - analysis | Gene Expression Profiling | Hypertrophy - pathology | Membrane Proteins - analysis | Trans-Activators - physiology | Hedgehog Proteins | Membrane Proteins - physiology | beta Catenin - physiology | Gene Expression Regulation, Developmental - physiology | Chondrocytes - pathology | Membrane Proteins - genetics | High Mobility Group Proteins - analysis | Core Binding Factor Alpha 1 Subunit - physiology | Signal Transduction - genetics | Fibroblasts - pathology | Reverse Transcriptase Polymerase Chain Reaction | Wnt Proteins - analysis | Blotting, Western | Mice, Knockout | Mice | Transcription Factors - analysis | Wnt Proteins - physiology | Growth Plate - physiopathology | SOX9 Transcription Factor | Collagen Type X - analysis | Collagen Type X - physiology | beta Catenin - analysis | Gene Expression Regulation, Developmental - genetics | RNA, Messenger - analysis | Trans-Activators - analysis | Hypertrophy - physiopathology | Intercellular Signaling Peptides and Proteins - physiology | Cell Differentiation - genetics | Transforming Growth Factor beta - analysis | Wnt Proteins - genetics | Chondrocytes - physiology | Trans-Activators - genetics | Bone Morphogenetic Proteins - genetics | Cell Differentiation - physiology | Osteogenesis - genetics | Fibroblasts - chemistry | Bone Morphogenetic Proteins - analysis | Collagen Type II - physiology | Transcription Factors - physiology | Bone Morphogenetic Protein 2 | RNA, Messenger - genetics | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Transforming Growth Factor beta - physiology | Collagen Type X - genetics | Transcription Factors - genetics | Collagen Type II - genetics | beta Catenin - genetics | Animals | Transforming Growth Factor beta - genetics | Signal Transduction - physiology | High Mobility Group Proteins - physiology | Core Binding Factor Alpha 1 Subunit - genetics | Growth Plate - chemistry | High Mobility Group Proteins - genetics | Index Medicus
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 07/2006, Volume 208, Issue 1, pp. 77 - 86
We investigated the molecular mechanisms underlying canonical Wnt‐mediated regulation of chondrocyte hypertrophy using chick upper sternal chondrocytes.... 
SYNOVIAL JOINT FORMATION | SIGNAL-TRANSDUCTION PATHWAYS | PHYSIOLOGY | RETINOIC ACID | RUNX/CBFA/AML FACTORS | WNT/BETA-CATENIN | BETA-CATENIN | PEPTIDE PTHRP | EXPRESSION IN-VIVO | SKELETAL DEVELOPMENT | BONE-DEVELOPMENT | CELL BIOLOGY | Chondrocytes - chemistry | TCF Transcription Factors - physiology | Bone Morphogenetic Proteins - physiology | Collagen Type II - analysis | Hypertrophy - pathology | Alkaline Phosphatase - physiology | beta Catenin - physiology | Chondrocytes - pathology | TCF Transcription Factors - analysis | Alkaline Phosphatase - genetics | High Mobility Group Proteins - analysis | Core Binding Factor Alpha 1 Subunit - physiology | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Wnt Proteins - analysis | Chick Embryo | Blotting, Western | Transcription Factors - analysis | Wnt Proteins - physiology | Mutation | SOX9 Transcription Factor | Collagen Type X - physiology | beta Catenin - analysis | RNA, Messenger - analysis | Avian Sarcoma Viruses - genetics | Promoter Regions, Genetic - genetics | Hypertrophy - physiopathology | Transforming Growth Factor beta - analysis | Transfection | Wnt Proteins - genetics | Chondrocytes - physiology | Alkaline Phosphatase - analysis | Electrophoretic Mobility Shift Assay | Bone Morphogenetic Proteins - genetics | Bone Morphogenetic Proteins - analysis | Collagen Type II - physiology | Transcription Factors - physiology | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Cells, Cultured | Transforming Growth Factor beta - physiology | Gene Expression Regulation - physiology | Collagen Type X - genetics | Transcription Factors - genetics | Collagen Type II - genetics | Animals | Promoter Regions, Genetic - physiology | Signal Transduction - physiology | High Mobility Group Proteins - physiology | TCF Transcription Factors - genetics | Core Binding Factor Alpha 1 Subunit - genetics | High Mobility Group Proteins - genetics | Index Medicus
Journal Article
Journal Article
Development (Cambridge), ISSN 0950-1991, 01/2017, Volume 144, Issue 2, pp. 221 - 234
Fractures heal predominantly through the process of endochondral ossification. The classic model of endochondral ossification holds that chondrocytes mature to... 
Pluripotency programs | Fracture repair | Endochondral ossification | Chondrocyte transformation | OSTEOBLAST DIFFERENTIATION | MARROW | DEVELOPMENTAL BIOLOGY | SIGNALING CENTER | MESENCHYMAL STEM-CELLS | CHONDROCYTE DIFFERENTIATION | CRE ACTIVITY | OCT4 EXPRESSION | IN-VIVO | HYPERTROPHIC CHONDROCYTES | SOX9 | Human Umbilical Vein Endothelial Cells | Bony Callus - growth & development | Chondrocytes - cytology | Osteogenesis - physiology | Humans | Male | Cell Transdifferentiation - genetics | Chondrocytes - physiology | Cartilage - cytology | Fracture Healing - physiology | Cartilage - physiology | Osteoblasts - cytology | Bone and Bones - cytology | Bone and Bones - physiology | Neovascularization, Physiologic - genetics | Mice, Inbred C57BL | Osteoblasts - physiology | Pluripotent Stem Cells - physiology | Cells, Cultured | Up-Regulation - genetics | Mice, Knockout | Chondrogenesis - physiology | Neovascularization, Physiologic - physiology | Animals | Mice | Fracture Healing - genetics | Bony Callus - metabolism | Callus | Transformation | Therapeutic applications | Oct-4 protein | Cell division | Bone healing | Osteoblasts | Endothelial cells | Ossification | Cartilage | Growth plate | Regeneration | Fractures | Molecular modelling | Rodents | Chondrocytes | Bone (endochondral) | Pluripotency | Hypertrophy | Apoptosis | Index Medicus | Stem Cells and Regeneration
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 03/2012, Volume 22, Issue 3, pp. 597 - 609
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2005, Volume 203, Issue 2, pp. 398 - 409
Human mesenchymal stem cells (hMSCs) expanded with and without fibroblast growth factor (FGF) supplementation were compared with respect to their proliferation... 
PROGENITOR CELLS | CROSS-TALK | PROTEIN-KINASE-C | IN-VITRO | PHYSIOLOGY | ATDC5 CELLS | DEFICIENT MDX MICE | STROMAL CELLS | GENE-EXPRESSION SIGNATURES | CHONDROCYTE DIFFERENTIATION | N-CADHERIN | CELL BIOLOGY | Chondrocytes - cytology | Chondrogenesis - drug effects | Age Factors | Oligonucleotide Array Sequence Analysis | Humans | Fibroblast Growth Factor 2 - pharmacology | Bone Marrow Cells - physiology | Gene Expression Profiling | Cell Culture Techniques - methods | Proteoglycans - drug effects | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Chondrocytes - physiology | Collagen - drug effects | Up-Regulation - physiology | Bone Marrow Cells - drug effects | Mesenchymal Stromal Cells - physiology | Mesenchymal Stromal Cells - drug effects | Tissue Engineering - methods | Bone Marrow Cells - cytology | Gene Expression Regulation - genetics | Extracellular Matrix Proteins - genetics | Cells, Cultured | Proteoglycans - metabolism | Down-Regulation - drug effects | Extracellular Matrix Proteins - drug effects | Down-Regulation - physiology | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Collagen - metabolism | Mitosis - drug effects | Mitosis - physiology | Signal Transduction - drug effects | Cell Differentiation - drug effects | Signal Transduction - physiology | Cell Proliferation - drug effects | Index Medicus
Journal Article