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cartilage (1072) 1072
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in-vitro (620) 620
collagen (581) 581
chondrocytes - drug effects (528) 528
chondrocytes - metabolism (525) 525
gene expression (511) 511
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cell differentiation (484) 484
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biotechnology & applied microbiology (453) 453
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articular-cartilage (405) 405
osteoarthritis (394) 394
gene-expression (384) 384
cell proliferation - drug effects (361) 361
regeneration (360) 360
tissue engineering - methods (358) 358
materials science, biomaterials (346) 346
analysis (336) 336
chondrogenesis - genetics (336) 336
repair (317) 317
osteogenesis - drug effects (315) 315
rats (310) 310
mesenchymal stem cells (306) 306
biochemistry & molecular biology (304) 304
bone (298) 298
bone marrow (295) 295
orthopedics (288) 288
stromal cells (285) 285
chondrogenic differentiation (284) 284
bone-marrow (281) 281
mesenchyme (281) 281
adult (272) 272
gene expression regulation - drug effects (270) 270
cell culture (267) 267
cell proliferation (265) 265
article (264) 264
osteogenesis (263) 263
collagen type ii - metabolism (258) 258
immunohistochemistry (257) 257
progenitor cells (255) 255
biomedical materials (253) 253
rabbits (251) 251
hydrogels (248) 248
proteins (241) 241
proliferation (230) 230
research (229) 229
tissue scaffolds - chemistry (229) 229
biocompatibility (228) 228
medicine, research & experimental (225) 225
scaffolds (222) 222
extracellular matrix - metabolism (220) 220
tissue (220) 220
bone marrow cells - cytology (218) 218
cell differentiation - physiology (215) 215
cell line (213) 213
cartilage - drug effects (212) 212
middle aged (210) 210
cartilage - cytology (209) 209
growth (208) 208
transplantation (208) 208
bone morphogenetic proteins (207) 207
glycosaminoglycans - metabolism (204) 204
cartilage - metabolism (200) 200
growth factors (199) 199
signal transduction (199) 199
research article (198) 198
cells (195) 195
developmental biology (193) 193
medicine (192) 192
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stem-cells (184) 184
physiological aspects (183) 183
arthritis (182) 182
stem cells - cytology (181) 181
extracellular-matrix (177) 177
human articular chondrocytes (175) 175
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Stem Cells, ISSN 1066-5099, 03/2010, Volume 28, Issue 3, pp. 564 - 572
Human mesenchymal stem cells (hMSCs) are multipotent cells that can differentiate into many cell types. Chondrogenesis is induced in hMSCs cultured as a... 
Cell shape | Rac1 | Chondrogenesis | Smooth muscle cells | N-cadherin | Mesenchymal stem cells | MYOBLAST FUSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | ADHESION | ONCOLOGY | MESENCHYMAL PROGENITOR CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE-EXPRESSION | CYTOSKELETAL TENSION | DIFFERENTIATION | RHO-GTPASES | PROTEINS | HEMATOLOGY | MODULATION | MAMMARY EPITHELIAL-CELLS | Chondrocytes - cytology | Chondrogenesis - drug effects | Cadherins - metabolism | Humans | Extracellular Matrix - metabolism | Antigens, CD - genetics | Cell Lineage - drug effects | Transforming Growth Factor beta3 - metabolism | Antigens, CD - metabolism | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Cadherins - genetics | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Chondrocytes - metabolism | Transforming Growth Factor beta3 - pharmacology | Mesenchymal Stromal Cells - drug effects | Cell Adhesion - genetics | Muscle Development - physiology | Cells, Cultured | Gene Expression Regulation - physiology | Mesenchymal Stromal Cells - metabolism | Up-Regulation - genetics | Antigens, CD - drug effects | Cadherins - drug effects | Cell Adhesion - drug effects | Cell Lineage - physiology | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Muscle Development - drug effects | rac1 GTP-Binding Protein - drug effects | Cell Differentiation - drug effects | Cell Shape - physiology | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Index Medicus
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2005, Volume 203, Issue 2, pp. 398 - 409
Human mesenchymal stem cells (hMSCs) expanded with and without fibroblast growth factor (FGF) supplementation were compared with respect to their proliferation... 
PROGENITOR CELLS | CROSS-TALK | PROTEIN-KINASE-C | IN-VITRO | PHYSIOLOGY | ATDC5 CELLS | DEFICIENT MDX MICE | STROMAL CELLS | GENE-EXPRESSION SIGNATURES | CHONDROCYTE DIFFERENTIATION | N-CADHERIN | CELL BIOLOGY | Chondrocytes - cytology | Chondrogenesis - drug effects | Age Factors | Oligonucleotide Array Sequence Analysis | Humans | Fibroblast Growth Factor 2 - pharmacology | Bone Marrow Cells - physiology | Gene Expression Profiling | Cell Culture Techniques - methods | Proteoglycans - drug effects | Cell Differentiation - genetics | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Chondrocytes - physiology | Collagen - drug effects | Up-Regulation - physiology | Bone Marrow Cells - drug effects | Mesenchymal Stromal Cells - physiology | Mesenchymal Stromal Cells - drug effects | Tissue Engineering - methods | Bone Marrow Cells - cytology | Gene Expression Regulation - genetics | Extracellular Matrix Proteins - genetics | Cells, Cultured | Proteoglycans - metabolism | Down-Regulation - drug effects | Extracellular Matrix Proteins - drug effects | Down-Regulation - physiology | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Chondrogenesis - physiology | Collagen - metabolism | Mitosis - drug effects | Mitosis - physiology | Signal Transduction - drug effects | Cell Differentiation - drug effects | Signal Transduction - physiology | Cell Proliferation - drug effects | Index Medicus
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 07/2004, Volume 77, Issue 2, pp. 192 - 204
Bone marrow stromal cells (MSC), which represent a population of multipotential mesenchymal stem cells, have been reported to undergo rapid and robust... 
transdifferentiation | mesenchymal stem cell | multipotential | neuronal differentiation | bone marrow | Mesenchymal stem cell | Bone marrow | Multipotential | Neuronal differentiation | Transdifferentiation | RAT | SPINAL-CORD | INTRACELLULAR CYCLIC-AMP | ADULT PROGENITOR CELLS | EMBRYONAL CARCINOMA | NEUROSCIENCES | MESENCHYMAL STEM-CELLS | NEURAL CELLS | DIMETHYL-SULFOXIDE | EXPRESSION | Chondrogenesis - drug effects | Osteogenesis - physiology | Actins - metabolism | Gene Expression Regulation, Developmental - genetics | Adipocytes - drug effects | Cell Lineage - drug effects | Fibroblasts - ultrastructure | Neurons - ultrastructure | Actin Cytoskeleton - drug effects | Neurites - ultrastructure | Nerve Tissue Proteins - biosynthesis | Stromal Cells - drug effects | Adipocytes - ultrastructure | Bone Marrow Cells - drug effects | Neurons - metabolism | Neurons - drug effects | Cell Differentiation - physiology | Neurites - drug effects | Fibroblasts - metabolism | Embryonic Induction - genetics | Actin Cytoskeleton - metabolism | Osteogenesis - drug effects | Stromal Cells - metabolism | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | Rats | Neurites - metabolism | Nerve Tissue Proteins - drug effects | Bone Marrow Cells - ultrastructure | Cell Lineage - physiology | Chondrogenesis - physiology | Phenotype | Stromal Cells - ultrastructure | Animals | Cell Differentiation - drug effects | Adipocytes - metabolism | Fibroblasts - drug effects | Culture Media - pharmacology | Biomarkers | Growth Substances - pharmacology | Actin Cytoskeleton - ultrastructure | Bone Marrow Cells - metabolism | Embryonic Induction - drug effects | Index Medicus
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 10/2017, Volume 32, Issue 10, pp. 2128 - 2141
Autophagy is activated during nutritionally depleted or hypoxic conditions to facilitate cell survival. Because growth plate is an avascular and hypoxic... 
ENDOCHONDRAL OSSIFICATION | AUTOPHAGY | GROWTH PLATE CHONDROCYTES | ATG7 | ER STRESS | MATRIX | CHONDROCYTES | ENDOPLASMIC-RETICULUM STRESS | CELL-DEATH | UNFOLDED PROTEIN RESPONSE | PATHWAY | ENDOCRINOLOGY & METABOLISM | GROWTH-PLATE | BONE | DIFFERENTIATION | Chondrogenesis - drug effects | Apoptosis - drug effects | eIF-2 Kinase - metabolism | Autophagy-Related Protein 7 - metabolism | Growth Plate - embryology | Cartilage - drug effects | Autophagy - drug effects | Chondrocytes - drug effects | Gene Deletion | Phenylbutyrates - pharmacology | Tibia - growth & development | Growth Plate - ultrastructure | Chondrocytes - metabolism | Femur - growth & development | Endoplasmic Reticulum Stress - drug effects | Osteogenesis - drug effects | Cells, Cultured | Femur - drug effects | Cartilage - metabolism | Growth Plate - metabolism | Organ Specificity | Tibia - drug effects | Autophagy-Related Protein 7 - genetics | Mice, Knockout | Animals | Activating Transcription Factor 4 - metabolism | Cell Differentiation - drug effects | Chondrocytes - ultrastructure | Cell Proliferation - drug effects | Embryonic Development - drug effects | Transcription Factor CHOP - metabolism | Autophagy-Related Protein 7 - deficiency | Analysis | Stress (Physiology) | Cell proliferation | Cell survival | Growth rate | Homeostasis | Collagenase 3 | Autophagy | Ossification | Cartilage | Growth plate | Bone growth | Rodents | Chondrocytes | Hypoxia | Chondrogenesis | Stress response | Endoplasmic reticulum | Bone (endochondral) | Phenylbutyric acid | Phagocytosis | Apoptosis | Index Medicus
Journal Article
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 12/2011, Volume 99A, Issue 3, pp. 467 - 478
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 10, pp. 2848 - 2857
Abstract Adult bone marrow derived mesenchymal stem cells are undifferentiated, multipotential cells and have the potential to differentiate into multiple... 
Advanced Basic Science | Dentistry | Cartilage | Silk fibroin | Chitosan | Tissue engineering | Mesenchymal stem cells | PORE-SIZE | MATERIALS SCIENCE, BIOMATERIALS | BOVINE ARTICULAR CHONDROCYTES | ENGINEERING, BIOMEDICAL | REGENERATION | CHITOSAN SCAFFOLDS | MESENCHYMAL STEM-CELLS | TISSUE ENGINEERING APPLICATIONS | 3D SCAFFOLDS | BIOMATERIALS | STROMAL CELLS | Chondrogenesis - drug effects | Rats, Wistar | Male | Cartilage - drug effects | Tissue Scaffolds - chemistry | Mesenchymal Stromal Cells - cytology | Flow Cytometry | Mesenchymal Stromal Cells - ultrastructure | Stromal Cells - drug effects | Chitosan - pharmacology | Bone Marrow Cells - drug effects | Extracellular Matrix Proteins - metabolism | Mesenchymal Stromal Cells - drug effects | Bone Marrow Cells - cytology | Cell Separation | Extracellular Matrix Proteins - genetics | Stromal Cells - metabolism | Cells, Cultured | Fibroins - pharmacology | Mesenchymal Stromal Cells - metabolism | Rats | Cartilage - metabolism | Cell Adhesion - drug effects | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Microscopy, Confocal | Animals | Cell Differentiation - drug effects | Fluorescent Antibody Technique | Cell Proliferation - drug effects | Porosity | Bone Marrow Cells - metabolism | Microscopy, Fluorescence | Stromal Cells - cytology | Silk | Glycosaminoglycans | Biological products | Collagen | Stem cells | Polyelectrolytes | Histochemistry | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 22, pp. 5571 - 5580
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 83, pp. 156 - 168
Abstract Conventional 3D printing may not readily incorporate bioactive ingredients for controlled release because the process often involves the use of heat,... 
Advanced Basic Science | Dentistry | Cartilage regeneration | Scaffold | MSC | Customized tissue engineering | 3D printing | HYDROGELS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | CHONDROGENIC DIFFERENTIATION | ACRYLATE | MESENCHYMAL STEM-CELLS | ELASTOMERS | SPHEROIDS | FABRICATION | LAYER | EXPRESSION | Chondrogenesis - drug effects | Chondrogenesis - genetics | Humans | Ink | Cell Aggregation - drug effects | Extracellular Matrix - metabolism | Hyaluronic Acid - pharmacology | Male | Polyethylene Glycols - chemistry | Cartilage - drug effects | Tissue Scaffolds - chemistry | Polyurethanes - pharmacology | Mesenchymal Stromal Cells - cytology | Solutions | Water - chemistry | Cartilage - physiology | Polyethylene Glycols - pharmacology | Amides - pharmacology | Biomarkers - metabolism | Transforming Growth Factor beta3 - pharmacology | Mesenchymal Stromal Cells - drug effects | Rabbits | Tissue Engineering - methods | Implants, Experimental | Polyurethanes - chemistry | Extracellular Matrix - drug effects | Gene Expression Regulation - drug effects | Regeneration - drug effects | Animals | Cell Proliferation - drug effects | Pyridines - pharmacology | Printing, Three-Dimensional | Delayed-Action Preparations | Crosslinked polymers | Tissue engineering | Stem cells | Hyaluronic acid | Transforming growth factors | Polyurethanes | Index Medicus | Polyurethane resins | Cartilage | Ingredients | Biochemistry | Scaffolds | Controlled release
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 3, pp. E338 - E347
Pathologic extraskeletal bone formation, or heterotopic ossification (HO), occurs following mechanical trauma, burns, orthopedic operations, and in patients... 
Cartilage | Heterotopic ossification | Mesenchymal condensation | HIF1α | Prx | HYPOXIA-INDUCIBLE FACTOR | PX-478 | RISK-FACTORS | MULTIDISCIPLINARY SCIENCES | cartilage | heterotopic ossification | RECEPTOR | mesenchymal condensation | CANCER | HUMAN SKELETAL-MUSCLE | BONE-FORMATION | IN-VIVO | HIF1 alpha | GROWTH-FACTOR | HIF-1-ALPHA | Ossification, Heterotopic - drug therapy | Chondrogenesis - drug effects | Mustard Compounds - pharmacology | Chondrogenesis - genetics | Tendons - drug effects | Humans | Tenotomy | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Luminescent Measurements | Gene Regulatory Networks - drug effects | RNA, Messenger - metabolism | X-Ray Microtomography | Adipose Tissue - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Tendons - surgery | Integrases - metabolism | Burns - complications | Wound Healing - drug effects | Disease Models, Animal | SOX9 Transcription Factor - metabolism | Mesenchymal Stromal Cells - drug effects | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Wounds and Injuries - pathology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | RNA, Messenger - genetics | Wounds and Injuries - complications | Ossification, Heterotopic - diagnostic imaging | Activin Receptors, Type I - metabolism | Sirolimus - pharmacology | Mice, Knockout | Up-Regulation - drug effects | Phenylpropionates - pharmacology | Animals | Signal Transduction - drug effects | Models, Biological | Tendons - pathology | Ossification, Heterotopic - prevention & control | Ossification, Heterotopic - genetics | Adipose Tissue - drug effects | Burns - genetics | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Journal Article