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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 13, pp. 4768 - 4773
Chondroitin sulfate proteoglycans (CSPGs) represent a major barrier to regenerating axons in the central nervous system (CNS), but the structural diversity of... 
Axons | Growth cones | Polysaccharides | Neurites | Receptors | Neurons | Antibodies | Epitopes | Sulfates | Sulfation | FUNCTIONAL RECOVERY | PROTEOGLYCANS | GLIAL SCAR | MULTIDISCIPLINARY SCIENCES | GROWTH | RECEPTOR | CNS | TYROSINE-PHOSPHATASE-SIGMA | SPINAL-CORD-INJURY | MICE | EXTENSION | Chondroitin Sulfate Proteoglycans - chemistry | Antibodies, Monoclonal - pharmacology | Nerve Regeneration - physiology | Neurites - enzymology | Axons - drug effects | Antibodies, Neutralizing - pharmacology | Antibodies, Blocking - pharmacology | Axons - physiology | Chondroitin Sulfates - chemistry | Growth Cones - pathology | Chondroitin Sulfate Proteoglycans - immunology | Epitopes - immunology | Animals | Growth Cones - metabolism | Signal Transduction - drug effects | Axons - pathology | Chickens | Receptor-Like Protein Tyrosine Phosphatases, Class 2 - metabolism | Mice | Growth Cones - drug effects | Carbohydrate Conformation | Ganglia, Spinal - drug effects | Chondroitin Sulfates - immunology | Ganglia, Spinal - metabolism | Carbohydrates | Physiological aspects | Regeneration (Biology) | Health aspects | Wounds and injuries | Antigenic determinants | Proteins | Nervous system | Cell growth | T cell receptors | Index Medicus | glycosaminoglycans | Biological Sciences | Physical Sciences | glycopolymers | protein tyrosine phosphatase | chondroitin sulfate proteoglycans (CSPGs) | chondroitin sulfate-E (CS-E)
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2012, Volume 18, Issue 19, pp. 5352 - 5363
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 10/2010, Volume 102, Issue 19, pp. 1496 - 1512
Background The cell surface proteoglycan, chondroitin sulfate proteoglycan 4 (CSPG4), is a potential target for monoclonal antibody (mAb)-based immunotherapy... 
STEM-CELLS | MELANOMA-ASSOCIATED ANTIGEN | MDA-MB-435 CELLS | ONCOLOGY | PHOSPHORYLATION | GENE-EXPRESSION PATTERNS | HMW-MAA | ANTIIDIOTYPIC MONOCLONAL-ANTIBODIES | CHONDROITIN SULFATE PROTEOGLYCAN | M14 MELANOMA | NG2 NULL MOUSE | Lung Neoplasms - drug therapy | Immunotherapy - methods | Apoptosis - drug effects | Breast Neoplasms - immunology | Humans | Immunoblotting | Lung Neoplasms - pathology | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Breast Neoplasms - metabolism | Pleural Effusion - pathology | Cell Movement - immunology | Chondroitin Sulfate Proteoglycans - drug effects | Signal Transduction - immunology | Flow Cytometry | Biomarkers, Tumor - metabolism | Female | Antineoplastic Agents - pharmacology | Disease Models, Animal | Cell Survival - drug effects | Antibodies, Monoclonal - pharmacology | Membrane Proteins - immunology | Cell Survival - immunology | Reverse Transcriptase Polymerase Chain Reaction | Breast Neoplasms - drug therapy | Chondroitin Sulfate Proteoglycans - immunology | Cell Movement - drug effects | Lung Neoplasms - immunology | Animals | Apoptosis - immunology | Confounding Factors (Epidemiology) | Signal Transduction - drug effects | Breast Neoplasms - pathology | Melanoma - immunology | Melanoma - drug therapy | Cell Line, Tumor | Membrane Proteins - drug effects | Aged | Cell Proliferation - drug effects | Mice | Care and treatment | Immunotherapy | Development and progression | Breast cancer | Genetic aspects | Research | Metastasis | Health aspects | Gene expression | Tumors | Index Medicus | Cell proliferation | Animal models | Cell survival | Proteoglycans | Statistical analysis | Tumor cells | Lung | Blood vessels | Pleural effusion | Regression analysis | Cell surface | Metastases | Nodules | Signal transduction | Xenografts | Monoclonal antibodies | Antitumor activity | Chondroitin sulfate | Microenvironments | Cell migration | Apoptosis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 2014, Volume 20, Issue 4, pp. 962 - 971
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2007, Volume 282, Issue 36, pp. 26409 - 26417
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 08/2010, Volume 59, Issue 8, pp. 1197 - 1209
Melanoma chondroitin sulfate proteoglycan (MCSP; also called CSPG4, NG2, HMW-MAA, MSK16, MCSPG, MEL-CSPG, or gp240) is a surface antigen frequently expressed... 
Cytolytic synapse | Epitope | T cell | MCSP | Melanoma | BiTE antibody | Redirected lysis | REGRESSION | SURVIVAL | CONSTRUCTS | MONOCLONAL-ANTIBODY | CANCER-IMMUNOTHERAPY | IMMUNOLOGY | THERAPY | ONCOLOGY | SPANNING PROTEOGLYCAN | NG2 | CHONDROITIN SULFATE PROTEOGLYCAN | TUMOR-GROWTH | Recombinant Fusion Proteins - immunology | Cricetulus | Chondroitin Sulfate Proteoglycans - chemistry | Humans | Antibodies, Bispecific - genetics | Antigens, Neoplasm - chemistry | Recombinant Fusion Proteins - metabolism | Single-Chain Antibodies - metabolism | Single-Chain Antibodies - genetics | Cancer Vaccines | Protein Engineering | Epitopes, T-Lymphocyte - immunology | CHO Cells | Cricetinae | Antigens, Neoplasm - immunology | Membrane Proteins - immunology | Melanoma - pathology | Antibodies, Bispecific - immunology | Chondroitin Sulfate Proteoglycans - immunology | Epitopes, T-Lymphocyte - chemistry | Animals | Antibodies, Bispecific - metabolism | Membrane Proteins - chemistry | Melanoma - immunology | CD3 Complex - immunology | Protein Binding | Recombinant Fusion Proteins - genetics | Melanoma - therapy | Single-Chain Antibodies - immunology | Cytotoxicity, Immunologic | Proteins | Oncology, Experimental | Monoclonal antibodies | Research | Sulfates | T cells | Cancer | Antigenic determinants | Protein binding | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 43, pp. 35860 - 35872
Journal Article
Protein Engineering, Design and Selection, ISSN 1741-0126, 09/2017, Volume 30, Issue 9, pp. 639 - 647
Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 2006, Volume 14, Issue 2, pp. 101 - 113
To identify the major aggrecanase- and matrix metalloproteinase (MMP)-generated aggrecan fragments in human osteoarthritis (OA) synovial fluid and in human OA... 
Cartilage | Synovial fluid | Aggrecan | Aggrecanase | Matrix metalloproteinase | Osteoarthritis | INTERGLOBULAR DOMAIN | BOVINE ARTICULAR-CARTILAGE | aggrecanase | osteoarthritis | cartilage | HYALURONAN | PROTEOLYSIS | RHEUMATOLOGY | aggrecan | CLEAVAGE-SITE | ADAMTS-4 | synovial fluid | G1 DOMAIN | matrix metalloproteinase | DEGRADATION | PROTEINS | ORTHOPEDICS | KERATAN SULFATE | Glycosaminoglycans - analysis | Humans | Lectins, C-Type - immunology | Cartilage, Articular - enzymology | Extracellular Matrix Proteins - analysis | Osteoarthritis - enzymology | Lectins, C-Type - metabolism | Protease Inhibitors - pharmacology | Knee Joint | Aggrecans | Peptide Fragments - immunology | Lectins, C-Type - analysis | Extracellular Matrix Proteins - metabolism | Chondroitin Sulfate Proteoglycans - analysis | Endopeptidases - metabolism | Blotting, Western - methods | Peptide Fragments - metabolism | Glycosaminoglycans - metabolism | Chondroitin Sulfate Proteoglycans - metabolism | Antibodies, Monoclonal - isolation & purification | Synovial Fluid - enzymology | Chondroitin Sulfate Proteoglycans - immunology | Peptide Fragments - analysis | Extracellular Matrix Proteins - immunology | Matrix Metalloproteinases - metabolism | Proteoglycans | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Klinisk medicin
Journal Article
Journal Article
Cancer Letters, ISSN 0304-3835, 10/2014, Volume 352, Issue 2, pp. 228 - 235
Highlights • Binding of a CSPG4-specific immunotoxin to rhabdomyosarcoma cells is demonstrated. • The IT is rapidly internalized into RMS cells and efficiently... 
Hematology, Oncology and Palliative Medicine | Immunotoxin | CSPG4 | Immunotherapy | Rhabdomyosarcoma | MOLECULAR CHARACTERIZATION | NUDE-MICE | MELANOMA-ASSOCIATED ANTIGEN | SINGLE-CHAIN IMMUNOTOXIN | BREAST-CANCER | ONCOLOGY | ALVEOLAR RHABDOMYOSARCOMA | ANTIBODY-BASED IMMUNOTHERAPY | CHONDROITIN SULFATE PROTEOGLYCAN | FACTOR-I RECEPTOR | EXPRESSION | Apoptosis - drug effects | Humans | Rhabdomyosarcoma - metabolism | Rhabdomyosarcoma - pathology | Immunotoxins - pharmacology | Exotoxins - metabolism | Dose-Response Relationship, Drug | Single-Chain Antibodies - metabolism | Time Factors | Immunotoxins - metabolism | Inhibitory Concentration 50 | Membrane Proteins - metabolism | Rhabdomyosarcoma - immunology | ADP Ribose Transferases - metabolism | Cell Survival - drug effects | Immunotoxins - immunology | Single-Chain Antibodies - pharmacology | Chondroitin Sulfate Proteoglycans - metabolism | Membrane Proteins - immunology | Exotoxins - pharmacology | Chondroitin Sulfate Proteoglycans - immunology | Bacterial Toxins - metabolism | Bacterial Toxins - pharmacology | ADP Ribose Transferases - pharmacology | Cell Line, Tumor | Protein Binding | Virulence Factors - metabolism | Single-Chain Antibodies - immunology | Virulence Factors - pharmacology | Tumors | Antigens | Pediatrics | Flow cytometry | Melanoma | Breast cancer | Metastasis | Cancer therapies | Patients | Proteins | Studies | Biopsy | Medical prognosis | Chondroitin sulfate | Mutation | Index Medicus
Journal Article